9 results about "Bone particle" patented technology

This invention discloses a biodegradable, highly bioactive magnesium bone particle, its preparation method, and its applications, belonging to the field of biomedical materials technology. Using magnesium bone particles as a matrix, an active composite coating layer comprising biodegradable polymer components and inorganic phase components is formed on its surface to construct biodegradable, highly bioactive magnesium bone particles. The biodegradable polymer components are one or more selected from polycaprolactone, polylactic acid, polylactic-co-glycolic acid copolymer, polyhydroxyalkanoates, chitosan, and their derivatives; the inorganic phase is one or more selected from hydroxyapatite, titanium dioxide, calcium phosphate materials, and combinations thereof. The preparation method includes magnesium bone particle matrix preparation, active composite layer slurry preparation, magnesium bone particle coating, and post-treatment. The prepared biodegradable, highly bioactive magnesium bone particles exhibit good degradation regulation performance and excellent bioactivity, and can be used in bone tissue engineering, bone defect repair, and scaffold filling fields.

The application provides a preparation method of a collagen-based bone filling material, comprising the following steps: S1) heating and performing heat crosslinking treatment on a decellularized matrix biomembrane, and then crushing the decellularized matrix biomembrane to obtain a matrix powder; S2) mixing the matrix powder with a solvent to perform whipping treatment, then adding inorganic bone particles to mix, and then performing freeze-drying and heat crosslinking treatment to obtain the collagen-based bone filling material. Compared with the prior art, the collagen-based bone filling material provided by the application is composed of a decellularized matrix biomembrane and natural inorganic bone particles, wherein the decellularized matrix biomembrane is subjected to heat crosslinking treatment, and then is subjected to crushing, swelling and whipping treatment, so that a stable three-dimensional network structure is formed; after physical crosslinking of the inorganic bone particles, the in-vitro degradation time is significantly prolonged; the bone filling material has no chemical reagent residue, has good biocompatibility, good resilience and plasticity, and is convenient to operate.

A surgical tool (10) for shaving and collecting bone particles, comprising: - a handle (20) provided with a handle (21); - a collection chamber (25) having a proximal end close to the handle (21) and a free distal end; - a stem (30) at least partially disposed within the collection chamber (25); - a blade body (40) fixed to a front end (32) of the stem (30), wherein the blade body (40) radially protrudes from the stem (30) and is axially disposed outside the collection chamber (25) in the vicinity of the distal end of the collection chamber (25); and - a spacer (50) interposed between a trailing face (42) of the blade body (40) and the distal end of the collection chamber (25), the trailing face (42) of the blade body (40) being kept at a predetermined non-zero axial distance from the distal end of the collection chamber (25) at least for a circumferential section of the spacer (50), wherein the spacer (50) defines a passage opening (500) for introducing the bone particles shaved by the blade body (40) into the collection chamber (25).

The invention relates to the technical field of crushing equipment, in particular to bone crushing equipment for bone grafting operation suitable for spine surgery. A bone crushing cavity is formed in the bone crushing machine, a bone crushing block is slidably connected to the bottom of the bone crushing cavity, and bone crushing teeth are arranged on the bone crushing block in the moving direction of the bone crushing block and the side wall of the bone crushing cavity in an array mode; an eccentric power mechanism and a pulse mechanism are arranged in the bone crushing block, the eccentric power mechanism is used for driving the bone crushing block to reciprocate, and the pulse mechanism is used for generating pulse jet flow at the bottom of the bone crushing cavity based on movement of the bone crushing block; a filtering mechanism used for filtering bone particles is further arranged on the side wall of the bone crushing cavity, a preset distance is formed between the filtering mechanism and the bottom of the bone crushing cavity, and the filtering mechanism communicates with a collecting mechanism used for collecting the bone particles. According to the invention, autologous bones can be efficiently treated, and high-quality bone particles with uniform sizes can be prepared.

The present application relates to a kind of mesoscopic modeling and analysis method of concrete structure, comprising the following steps: step 1) according to the size characteristic parameter of concrete component, determine lattice node coordinates, and connect lattice node to obtain the frame of lattice model, wherein the lattice model includes lattice node and the lattice unit connected between lattice node each other;Step 2) according to the grading of each component material used by concrete material, determine the particle size and quantity of coarse aggregate and the mesoscopic two-dimensional parameter of each component of concrete;Step 3) generate coarse bone particle mesoscopic random distribution model based on random distribution algorithm, the particle size and quantity of coarse aggregate, and according to the mesoscopic random distribution model of coarse aggregate, give the corresponding material attribute and element attribute of lattice unit, obtain lattice model;Step 4) import lattice model into ABAQUS secondary development platform, and carry out load calculation.Compared with prior art, the present application comprehensively considers the mesoscopic structure characteristics of concrete material, and provides a refined numerical simulation idea.

The utility model discloses a bone grafting set device for minimally invasive spinal surgery, which comprises a sleeve, an armrest frame is embedded and fixed at the lower part of the outer side of the sleeve, a conveying pipe is embedded and fixed at the center of the bottom of the sleeve, a sliding block is matched with the inner side of the conveying pipe in an up-and-down sliding manner, a straight rack is fixedly connected at the center of the top of the sliding block, and the straight rack is fixedly connected with the handle. A transmission gear is rotationally meshed with the left side of the spur rack, the transmission gear leftwards extends out of the sleeve, a gap is reserved between the transmission gear and the sleeve, the outer side of the transmission gear is covered with a protective shell sleeve in an isolated mode, a rotating shaft is fixedly connected to the center of the front side of the transmission gear, and a distance adjusting knob is fixedly connected to the outer side of the front end of the rotating shaft; a common linear pushing mode is replaced with a gear rotating meshing mode, more stable controllability is achieved, force control is more accurate, the bone grain extrusion rate is more stable, in addition, compared with a partial spiral pushing mode, the transmission effect is more direct, and the extrusion rate is higher.

A surgical tool (10) for scraping and collecting bone particles, comprising: —a handle (20) provided with a handgrip (21); —a collection chamber (25) having an end proximal to the handgrip (21) and a free distal end; —a stem (30) at least partially arranged inside the collection chamber (25); —a blade (40) fixed to a front end (32) of the stem (30), wherein the blade (40) protrudes radially from the stem (30) and is axially arranged outside the collection chamber (25) near the distal end thereof; and—a spacer (50) interposed between a rear face (42) of the blade (40) and the distal end of the collection chamber (25), wherein the spacer (50) defines a passage opening (500) for introducing the bone particles scraped by the blade (40) into the collection chamber (25), maintaining at a predetermined non-zero axial distance, for at least a circumferential tract thereof, the rear face (42) of the blade (40) from the distal end of the collection chamber (25).

A method of making infused bone particles employs the following steps: cutting or shaving whole bone into bone particles, washing the bone particles, demineralizing or decalcifying at least partially the whole bone or bone particles and infusing the bone particles with a supernatant of biologic material or a polyampholyte cryoprotectant or a combination of both to create infused bone particles. The step of infusing includes exposing the bone particles to a negative pressure or vacuum to draw the supernatant and / or the polyampholyte cryoprotectant into the bone particles, or alternatively, exposing the demineralized whole bone to a positive pressure to drive the supernatant and / or the polyampholyte cryoprotectant into the bone. The resultant method creates an infused bone grafting composition having bone particles taken from whole bone, demineralized or decalcified at least partially and infused with one or more of a supernatant of biologic material or a polyampholyte cryoprotectant or both.

This utility model relates to the field of low-temperature grinding, and more particularly to a low-temperature bone meal grinding device. This utility model provides such a low-temperature bone meal grinding device, including a shell, controller, cover, grinding barrel, grinding chamber, drive motor, and rotating shaft. The controller is installed on the front side of the shell, and the cover is rotatably connected to the top of the shell. The grinding barrel is fixedly connected to the inner side of the upper part of the shell, and the grinding chamber is fixedly connected to the inner side of the lower part of the shell. The discharge port at the bottom of the grinding barrel is fixedly connected to the grinding chamber. The drive motor is installed on the top of the cover and is electrically connected to the controller. The rotating shaft is fixedly connected to the output shaft of the drive motor. This utility model utilizes a collaborative working mechanism between the grinding head, slide bar, and spring. When the grinding head encounters a strong impact from hard bone particles, the spring can absorb and disperse part of the impact force, effectively reducing the instantaneous pressure on the grinding head.