42 results about "Lysine diisocyanate" patented technology

Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.

The present invention relates to a linear polyureaurethane polymer, comprising in its hard blocks, at least two urea groups. The hard block of the polyureaurethane material is preferably synthesized by using diisocyante groups in the form of lysine diisocyanate (LDI). The soft block component of the polyureaurethane material is preferably poly(epsilon-caprolactone) (PCL). The invention also relates to a method of producing a polyureaurethane polymer, which in short comprises the steps of reacting a soft block component with a diisocyante group in order to prepare a prepolymer component, combining the prepolymer component with a catalyst in order to define a reaction solution and adding water to the reaction solution, preferably carried to the reaction solution in vapour phase.

The present invention relates to a linear polyureaurethane polymer, produced without the use of any chain extender. The hard block of the resulting polymer thus consists of diisocyante groups linked to each other via without the presence of any chain extender component. The hard block of the polyureaurethane material is preferably synthesized by using diisocyante groups in the form of lysine diisocyanate (LDI). The soft block component of the polyureaurethane material is preferably poly(epsilon-caprolactone) (PCL). The invention also relates to a method of producing a polyureaurethane polymer, which in short comprises the steps of reacting a soft block component with a diisocyante group in order to prepare a prepolymer component, combining the prepolymer component with a catalyst in order to define a reaction solution and adding water to the reaction solution, preferably carried to the reaction solution in vapour phase.

The invention relates to a method in the technical field of medical materials and in particular relates to a preparation method of an LDI-PCLLA-PEG-PCLLA/hydroxyapatite electrospun fiber membrane as well as a product and application thereof. The preparation method comprises the following steps: taking a main component of a body cross-linked structure biological scaffold which takes polycaprolactone polylactic acid-polyethylene glycol-polylactic acid (PCLLA-PEG-PCLLA) as a soft segment and takes L-lysine diisocyanate (LDI) as a hard segment, taking nano-sized hydroxyapatite particles as an inorganic filling material, and performing electrostatic spinning, thereby obtaining the composite nano fiber membrane. The compounded fiber membrane scaffold achieves effects of promoting bone growth andinducing osteoblast differentiation of cells.

The invention relates to the technical field of biodegradable materials, specifically to a preparation method for a fully-synthetic biodegradable high-strength hemostatic foam applicable to hemostasisof cavities like ears and noses of human or animals. The biodegradable high-strength polyether ester type polyurethane urea foam is prepared from a polyether ester type polyurethane urea material through freeze-molding, wherein the polyether ester type polyurethane urea is prepared through chain extension of dihydroxy-terminal triblock prepolymer by using diisocyanate with a urea structure as a chain extender; the polyurethane urea material has a number average molecular weight of 1.1 x 105 to 1.8 x 105 and a dispersion coefficient of 1.18 to 1.51; and the diisocyanate chain extender containing the urea structure is selected from the group consisting of L-lysine diisocyanate-1,4-butadiamine-L-lysine diisocyanate and L-lysine diisocyanate-1,6-hexane diamine-L-lysine diisocyanate.

The invention discloses degradable foamed plastic and a preparation method thereof. The degradable foamed plastic consists of the following components in parts by mass: 60-80 parts of polylactic acid, 20-30 parts of starch, 1.2-3.6 parts of lysine diisocyanate, 5-15 parts of polycaprolactone, 1-6 parts of trimethylolpropane, 1-3 parts of tetrabutyl titanate, 1-5 parts of polyvinyl ester, 1-3 parts of maleic anhydride, 3-8 parts of glycerol, 2-5 parts of a plasticizer, 1-3 parts of an antioxidant and 2-5 parts of a foam stabilizer. The preparation method of the degradable foamed plastic comprises the following steps: uniformly mixing polycaprolactone, polylactic acid and starch, stirring, then, adding maleic anhydride, lysine diisocyanate, trimethylolpropane, tetrabutyl titanate, the polyvinyl ester and glycerol to mix and stir for 20-40 minutes, adding the rest of the components, putting the mixture into an oven to cure, and taking out the mixture after 20 minutes to obtain a finished product degradable foamed plastic. The preparation process is simple and easy to implement, and the prepared foamed plastic is high in degradation rate and short in degradation period.

The invention discloses a nanometer waterborne polyurethane adhesive and a preparation method therefor. The nanometer waterborne polyurethane adhesive comprises the following components in parts by weight: 20-30 parts of polycaprolactone diol, 10-15 parts of isophorone diisocyanate, 2-6 parts of polyether triol, 3-6 parts of dibutyl phthalate, 0.2-0.8 part of dibutyltin dilaurate, 0.1-0.3 part of ethylene glycol monomethyl acetate, 0.3-0.9 part of trimethylolpropane trimester, 0.2-0.5 part of ethoxy lauryl alcohol, 0.3-0.7 part of lysine-di-isocyanate, 5-10 parts of polyhydric alcohols, 1-4 parts of polyamine, 1-3 parts of sodium alkyl benzene sulfonate, 2-5 parts of sodium dodecyl benzene sulfonate, 1-2 parts of curing agent and 20-40 parts of water. A sulfonate radical hydrophilic chain extender is adopted in the adhesive, the water resistance is improved, the cross-linking agents such as polyhydric alcohols and polyamine are added in a polyurethane system, and the adhesive strength of the adhesive is improved.

The invention discloses an environment-friendly oil-resistant rubber sealing piece and a preparation process thereof. The sealing piece is prepared from the following raw materials: natural rubber, nitrile rubber, silicon rubber, butylene succinate, p-t-octylphenol formaldehyde resin, calcium stearate, L-lysine diisocyanate, crylic acid-acrylonitrile copolymer, ethylene-octylene-alkadiene terpolymer, spraying carbon black, copper ammonia fibers, ethylene glycol salicylate, tea-seed oil acid, tetrachlorophthalic acid dioctyl phthalate, tri-n-butyl citrate, an aluminate coupling agent, dicumyl peroxide, 2,4-DCBP, zinc dibutyl dithiocarbamate, zinc oxide, N-octyl N-octadecyl sulfo-amino MoDDC and butyl acetate. The rubber sealing piece provided by the invention is high in oil resistance and comprehensive mechanical property, green and environment-friendly, and is very suitable for being used as the rubber sealing piece widely applied to various fields.

A novel high-performance biodegradable plastic material based on biodegradable polyester and starch applying LDI(L-Lysine Diisocyanate) as coupling agent.

The invention discloses a production method of bio-based solvent-free polyurethane. The method comprises the following steps: S1, adding a bio-based polymer, polycaprolactone, amino acid diisocyanate,a processing agent, an auxiliary agent and an auxiliary material into a reaction kettle, and uniformly stirring to obtain a mixture; and S2, detecting the obtained mixture, carrying out filtering packaging the qualified product after inspection, and carrying out sub-packaging storage by weight, wherein the viscosity of the bio-based polymer is less than 3000 mPa.S, the bio-based raw material hasthe content of greater than 60%, is prepared by mixing any one or more than two of Sovermol1092, Sovermol810 and Sovermol760 according to any ratio, and does not contain a solvent, the amino acid diisocyanate is lysine diisocyanate or L-lysine diisocyanate and is a degradable non-toxic material, and the processing agent comprises a cross-linking agent and a chain extender. According to the production method of the bio-based solvent-free polyurethane, the reaction effect and the efficiency can be improved, and the overall quality can be improved.

The invention provides a rapidly solidified adhesive. The rapidly solidified adhesive is prepared from the following raw materials in parts by weight: 3-10 parts of lysine diisocyanate, 2-8 parts of Kathan, 3-9 parts of nano-zinc oxide, 4-8 parts of ethyl acetate, 3-7 parts of epoxy diluent, 4-10 parts of dimethylaniline, 2-5 parts of polyacrylamide, 3-8 parts of epoxy resin, 4-7 parts of stearic acid, 1-3 parts of insoluble sulfur, 1-5 parts of fortifier, 1-3 parts of accelerant, 5-9 parts of butadiene styrene rubber and 15-22 parts of propylene glycol monomethyl ether acetate. The rapidly solidified adhesive has the beneficial effects of the capability of rapid solidification, and meanwhile, wide application range, applicability to cementing a plurality of materials, and great economic value.

The invention relates to a waterproof cis-1,4-polybutadiene rubber modified epoxy resin anticorrosive paint. The invention is characterized in that the paint is prepared from an epoxy resin E51, cis-1,4-polybutadiene rubber, dichlorobenzene, benzoyl hydroperoxide, molybdenum trioxide, sodium periodate, sodium tartrate, lysine diisocyanate, diethylaminoethanol, aniline, polystyrene hollow microspheres, phosphoric acid, ammonium persulfate, stearin, dimethylbenzene, n-butanol, nano tin oxide, nano magnesium oxide, dodecyl alcohol ether sodium sulfate, bis imidazolidinyl urea, N,N-di(2-hydroxypropyl) aniline, chloroform and a proper amount of deionized water. The anticorrosive paint provided by the invention has the advantages of high saline water resistance, favorable corrosion resistance, no toxicity and environment friendliness and the like.

The invention provides a polyvinyl alcohol film and a preparation method thereof, and belongs to the field of biodegradable materials. The polyvinyl alcohol film is prepared from the following raw materials in parts by weight: 100 parts of polyvinyl alcohol, 60-120 parts of starch, 10-30 parts of a reinforcing agent, 0.1-1 part of lysine diisocyanate and 5-10 parts of a plasticizer, the polymerization degree of the polyvinyl alcohol is 1500 to 3500, and the alcoholysis degree of the polyvinyl alcohol is 85 to 99 percent. According to the invention, lysine diisocyanate is adopted to carry out reaction compatibilization on PVA and starch molecules, so that the compatibility of two phases can be improved; by adopting the plasticizer, the melting temperature of the PVA composite material can be reduced by reducing the intermolecular or intramolecular hydrogen-bond interaction of PVA and starch. Through cooperation of the raw materials, the obtained polyvinyl alcohol film shows excellent strength and toughness in the transverse direction and the longitudinal direction, and has high tensile strength and elongation at break.

The invention belongs to the field of medicines, and provides a functional polymerization type polyurethane prodrug polymer nano diagnosis and treatment agent, PUCPt is prepared from cyanine dye, cis, cis, trans-[Pt (NH3) 2Cl2 (OH) 2], lysine diisocyanate and polyethylene glycol monomethyl ether derivatives as raw materials. The main chain type platinum (IV) and cyanine dye (HOCyOH) multifunctional polymeric polyurethane prodrug polymer PUCPt provided by the invention is of an amphiphilic structure, can be self-assembled into nano particles in an aqueous solution, has relatively high drug loading capacity and drug loading efficiency, and shows effective intracellular uptake and enhanced cell proliferation inhibition effects on cancer cells. PUCPt, PUCPt NPs, or drug delivery systems comprising them are promising platforms for platinum and HOCyOH co-based multimode imaging, photothermal therapy in combination with chemotherapy.

The invention discloses a phosphorus-nitrogen flame retardant and a preparation method thereof. The phosphorus-nitrogen flame retardant is prepared from the following raw materials: isocyanate, a phosphorus-containing compound DOPO, a solvent and a catalyst, wherein isocyanate includes toluene diisocynate, isophorone diisocyanate, diphenylmethane diisocyanate, dicyclohexylmethane diisocyanate, hexamethylene diisocyanate, lysine diisocyanate and polyisocyanate; and the solvent comprises one or more of benzene, methylbenzene, dimethylbenzene, acetone, butanone, cyclohexanone, dichloromethane, trichloromethane and petroleum ether, a catalyst is added into the solvent, and the catalyst is an imidazole catalyst. The phosphorus-nitrogen flame retardant disclosed by the invention has the advantages of low smoke, low toxicity, high efficiency, good thermal stability, good compatibility with a polymer substrate, migration and volatilization resistance, lasting flame-retardant effect and the like. According to the preparation method provided by the invention, the phosphorus-nitrogen flame retardant can be prepared through a one-step addition reaction, the process steps are simple, the operation is easy, and the preparation method is suitable for large-scale popularization.