19 results about "Sample viscosity" patented technology

The invention provides an automatic sample distribution method for flow cytometry, which belongs to the technical field of flow cytometry and comprises the following steps: acquiring basic information of a sample; the method comprises the following steps: pre-analyzing a sample through a micro-fluidic chip to obtain sample density, sample viscosity and sample ion concentration; measuring the micro-channel diameter and the micro-channel length of the micro-fluidic chip by adopting a laser ranging system, and recording the characteristic parameters of the micro-channel material; a target distribution volume is set, a high-precision injection pump system is started for pre-injection, and an initial distribution rate is obtained through measurement of a flow sensor; calculating the initial distribution rate by using a fluid dynamic compensation equation set to obtain a corrected distribution rate; controlling the high-precision injection pump system to perform sample distribution according to the corrected distribution rate; performing real-time monitoring on a sample liquid level by using an ultrasonic sensor, and synchronously acquiring a real-time distribution rate; and sample shunting is performed through the micro-fluidic chip, so that multi-channel parallel distribution is realized.

The invention discloses a full-automatic liquid sample injection analysis system and method. The system comprises a sample management module, a full-automatic sample injection module, a sample pretreatment module, an analysis detection module, a data processing and analysis module, a system control module, a user interaction module and a safety protection module, according to the invention, through seamless connection of sample management, sample introduction, pretreatment, detection and data processing, unattended analysis of batch samples is realized; a sample size correction formula is introduced, and the sample size is dynamically adjusted by combining the viscosity and temperature of the sample, so that the problem that the traditional sample injection is influenced by environment and sample characteristics is solved. A wall-hanging-preventing sample injection needle of the full-automatic sample injection module and a high-pressure bidirectional cleaning process are matched with a secondary cleaning mechanism of turbidity monitoring, so that sample residues and cross contamination are effectively avoided.

The invention discloses a dynamic liquid level detection system and method based on a capacitance-photoelectric dual-mode sensor, and the system comprises a dual-mode sensor module which comprises a capacitance sensor used for measuring the capacitance value change caused by the liquid level change; the photoelectric sensor is used for measuring the light intensity change caused by the liquid level change; the signal processing module is used for processing original signals of the capacitive sensor and the photoelectric sensor; the dynamic calibration module comprises a temperature sensor and a microcontroller MCU, and the microcontroller MCU is configured to receive and process the signal from the signal processing module; dynamically adjusting the excitation frequency of the capacitive sensor according to the temperature value read by the temperature sensor and a preset sample viscosity type; based on a self-adaptive weighted fusion algorithm, fusing the processed capacitance signal and the photoelectric signal, and outputting final liquid level information; and when bubbles are detected, the control system is switched to a pure capacitance detection mode. According to the invention, high-precision liquid level detection can be realized.

The invention relates to SBS modified asphalt viscosity detection equipment, and relates to the technical field of asphalt detection equipment, the SBS modified asphalt viscosity detection equipment comprises a rack and a detector arranged on the rack and used for detecting the viscosity of a sample, a sample cup used for storing the sample is arranged below the rack, and a lifting part used for driving the detector to lift is arranged on the rack; a heat preservation shell is arranged outside the rack, and a heat preservation seat for bearing a sample cup is arranged inside the heat preservation shell; an electric heating piece used for heating air in the heat preservation shell is arranged in the heat preservation shell. A heating assembly used for heating a sample is arranged in the heat preservation shell, and a control assembly used for controlling the heating assembly according to the temperature of the sample is arranged in the heat preservation shell; a storage opening used for storing the sample cup is formed in the side wall of the heat preservation shell in a penetrating mode, and a moving assembly used for driving the heat preservation base to move between the storage opening and the detector in a reciprocating mode is arranged in the heat preservation shell. According to the method, the influence of the environment temperature on the viscosity detection accuracy of the modified asphalt is reduced, and the viscosity detection accuracy of the modified asphalt is improved.

Sensors employing bulk acoustic wave (BAW) resonators are used to assay characteristics of blood. The BAW sensors may be used to sense viscosity of a sample comprising blood to determine coagulation properties of the blood. The viscosity of the blood may be evaluated in the presence of agents that inhibit coagulation or that promote coagulation. The change in viscosity of the sample in the presence of such agents may provide information regarding whether the blood suffers from a coagulation disorder.

The utility model discloses a flow cytometer sorting liquid drop anti-adhesion flow guide device which comprises an installation shell, an installation cover is fixed on the side wall of the installation shell, a detection mechanism is arranged on the outer side of the installation cover, an installation support is fixed on the inner wall of the installation shell through bolts, a material storage mechanism is arranged on the top of the installation support, and a flow cytometer is arranged on the material storage mechanism. A sorting mechanism is arranged at the bottom of the storage mechanism, a flow guide mechanism is arranged at the bottom of the sorting mechanism, and an airflow compensation mechanism is arranged on the outer side of a flow guide pipe. The flow guide mechanism is arranged to guide sheath fluid, so that sheath fluid residues can be effectively reduced, cross contamination is avoided, frequent shutdown for cleaning is not needed, the continuity of the flow cytometer during use is guaranteed, flow guide parameters of the flow guide mechanism are adjusted through the airflow compensation mechanism, and the flow cytometer adapts to viscosity and liquid drop speed changes of different samples; and the angle deviation of liquid drop collision is reduced, so that the adhesion risk of liquid drops with different specifications is reduced.

The invention relates to the technical field of biomedical detection, in particular to a rapid detection method for a specific biomarker of precocious puberty of central girls. When a blood sample is detected, an original light intensity sequence of the chromatographic test strip is obtained and adjusted into a standardized net signal sequence; the color band width is controlled by the chromatography flow velocity and can reflect the fluid diffusion level under the sample viscosity, so that the quality control line reference width and the waveform sharpness are determined, and the waveform distribution characteristics are grasped; if the blood viscosity is increased, the light intensity of quality control and interference capture intervals is distorted, and when the light intensity of the interference capture intervals meets preset conditions, saturation evaluation indexes are determined according to peak shape characteristics and quality control line related parameters of the interference capture intervals, and the saturation degree is evaluated; analyzing the light intensity in a membrane gap interval to obtain a background trailing ratio, and quantifying the leakage flux of free interferents; finally, the saturation evaluation index and the background trailing ratio are fused to obtain a blood sample effective value, the sample condition can be comprehensively and accurately reflected, and whether the sample is suitable for detection or not can be determined.

The invention discloses a magnetic field determination method and device for crude oil viscosity reduction and a storage medium, relates to the technical field of data processing, and aims to solve the problems of high energy consumption and environmental pollution of a crude oil viscosity reduction method. The magnetic field determination method for crude oil viscosity reduction comprises the following steps: acquiring working parameters of a first magnetic field acting on crude oil in a target pipeline; the working parameters comprise action time, magnetic field intensity and frequency; and controlling an inverter deployed in the target pipeline to excite the first magnetic field according to the working parameters so as to adjust the sample viscosity of the crude oil in the target pipeline based on the first magnetic field.

The invention discloses an anti-clogging centrifugal cell sorting device and a use method thereof, and belongs to the technical field of cell sorting, a rotating handle in an adjusting assembly is rotated, a sliding seat presses four hinge rods downwards, the bottom ends of the four hinge rods expand outwards and push a movable frame to deflect, and the cell sorting efficiency is improved. The movable frame drives the protective sleeve to rotate through the two rotating shafts, the protective sleeve drives the centrifugal tubes in the protective sleeve to deflect with the rotating shafts as the center, in the process, the bottoms of the multiple centrifugal tubes are unfolded outwards, the centrifugal angle is increased, when the centrifugal angle is adjusted to be small, a rotating handle is rotated reversely, and in the same way, a sliding base pulls multiple hinge rods upwards, so that the centrifugal tubes are adjusted to be small. Meanwhile, the pointer at the top of the top cover points to the bevel protractor, so that the centrifugal angles are conveniently and accurately adjusted, and the centrifugal angles of the centrifugal tubes are synchronously adjusted in the centrifugal process so as to adapt to the viscosity or density gradient requirements of different samples; the cell layering definition is optimized; the separation purity is improved.

The invention relates to the technical field of biological detection, and discloses a saliva exosome detection kit for non-invasive auxiliary screening of Alzheimer's disease and a preparation method of the saliva exosome detection kit. The specific exosome enrichment system composed of the anti-L1CAM / CD63 double antibody coated capture plate and the anti-MUC1 / KRT19Fab fragment blocking agent is constructed for the first time, about 85% of oral cavity source exosomes can be effectively removed, and the capture purity of neuron source exosomes is remarkably improved; the special saliva preserving fluid containing DTT and a specific enzyme inhibitor is developed, the technical bottlenecks that saliva RNA is easy to degrade and a sample is uneven in viscosity are overcome, and the room temperature stability is prolonged to 8 hours; an RT-qPCR detection system taking saliva exosome miRNA-135a as a core and taking internal reference miRNA-16-5p standardization is established, and clinical sample verification shows that the kit can effectively distinguish the Alzheimer's disease patient from a healthy control, shows excellent inter-group distinguishing ability, and provides a stable, efficient, reliable and complete technical scheme for solving the problem of AD non-invasive early screening.

A control method for an automatic analyzer that can improve robustness, throughput, and measurement accuracy. The automatic analyzer includes a sample loop connected between two sample ports of a plurality of sample ports of a switch valve. The method includes the steps of: adjusting a drive parameter of the syringe corresponding to a viscosity of the sample acquired in advance; switching the switch valve to a first state in which the sipper and the syringe contact with each other without through the sample loop; driving the syringe based on the drive parameter to draw and introduce the sample through the sipper; switching the switch valve to a second state in which the syringe and the sample loop conduct with each other; and driving the syringe based on the drive parameter to introduce the sample into the sample loop.

The invention discloses a quantitative analysis method for heavy metals in water, and relates to the technical field of heavy metal quantitative analysis data processing. The quantitative analysis method for the heavy metals in the water comprises the following steps: analyzing a lead sample collection process; pre-treating and analyzing a lead sample; and analyzing the lead element detection stability. According to the method, the acquisition process analysis is performed through the availability data of the specified lead sample in the distributed water source area, whether the viscosity of the lead sample is optimized is judged, and then the pretreatment analysis is performed based on the pretreatment validity data in the distributed water source area so as to judge whether the digestion acid parameter optimization is performed; and finally, stability analysis is performed based on detection stability data in the distributed water source area, and whether circuit noise parameter optimization is performed or not is judged, so that the effect of improving the accuracy of quantitative analysis of the lead element in the distributed water source in the rural area where debris flow frequently occurs is achieved. The problem that in the prior art, quantitative analysis accuracy of lead elements in distributed water sources in rural areas where debris flow occurs frequently is not high is solved.

The utility model relates to double -chamber series connection type dilution pretreatment device, aims at solving current double -chamber series connection structure, and the mixing assembly of connecting pipeline is static design more, when processing high viscosity sample or the scene of flow fluctuation is bigger, easy to appear " short circuit flow " or " dead volume " phenomenon, lead to dilution evenness decline, influence the quality of the technical problem of pretreatment, including: bottom plate, bottom plate top two sides are equipped with first pretreatment cavity and second pretreatment cavity respectively, first pretreatment cavity height is higher than second pretreatment cavity, and both are connected in series through intercommunication mechanism, the utility model can adjust mixing intensity in real time according to sample viscosity and flow fluctuation through drive assembly drive mixing assembly active rotation, avoid static spiral piece or baffle appearing " short circuit flow " when flow sudden change, namely liquid is not mixed directly through fully, ensure that sample and diluent form global turbulence in connecting pipe, eliminate " dead volume ".

The application discloses a kind of targeted thickening polymer shell breaking and effect time test determination methods, comprising the following steps: S1 preparation targeted thickening polymer solution;S2 targeted thickening polymer solution oxygen removal;S3 test different time point sample viscosity;S4 draw sample different aging time and viscosity curve, determine targeted thickening oil displacement agent initial shell breaking time point and effect time point, the application is applicable to oil and gas field development technical field, by simulating formation environment to test shell breaking and effect time, for different types of reservoirs to provide strong basis for optimum polymer, monitor the performance of targeted thickening polymer, ensure the injection quality of polymer in the field, simple to operate, short time, high efficiency, for improving chemical oil displacement precision, more significantly improve recovery, with great research value and application prospect.

The utility model relates to the technical field of viscosity measurement, and particularly discloses a viscometer with a constant temperature function, the viscometer comprises a viscometer body, a measurer, a sample tube and a constant temperature device, the constant temperature device comprises a heat preservation sleeve, the sample tube is wrapped with the heat preservation sleeve, a sealed heat preservation gap is formed between the inner wall of the heat preservation sleeve and the outer wall of the sample tube, and the heat preservation sleeve is arranged in the heat preservation gap. The heat-insulating gap is used for accommodating a heat-insulating medium; a flow inlet and a flow outlet are formed in the side wall of the heat preservation sleeve and communicate with the heat preservation gap. The temperature of the to-be-measured sample can be controlled when the viscometer is used for measuring, the influence of the temperature on the viscosity of the to-be-measured sample during measurement is reduced, and the viscosity measurement result is more accurate.

A method ascertains the viscosity of a sample using a rotary viscosimeter. A measuring body is arranged on a measuring shaft, and a second measuring part is arranged on the rotary viscosimeter. The distance between the measuring body and the second measuring part is reduced until a flow can pass between the measuring body and the second measuring part, thus defining a zero distance between the measuring body and the second measuring part. The distance between the measuring body and the second measuring part is increased from the zero distance such that a defined measuring gap is set. The second measuring part is removed, a sample is introduced into the second measuring part, and the second measuring part is repositioned. A viscosity measurement is carried out on the sample, and the viscosity of the sample is determined by an analysis unit.

The invention relates to the technical field of automatic control of dyeing equipment, and discloses a control method and system of an integrated flaking and dyeing all-in-one machine, and the method comprises the following steps: synchronously collecting a flow resistance signal and a light transmittance signal of a cell sample; establishing lesion cell sedimentation sensitive parameters; calculating a safe angular velocity interval and a safe centrifugation time interval of layered centrifugation; executing layered centrifugal correction; and executing compensation centrifugal control. In the prior art, a scheme of performing slide preparation control by depending on fixed centrifugal parameters or experience setting, and especially under the condition of large difference or obvious fluctuation of sample viscosity and cell load, sufficient retention of pathological cells and background cleanliness are difficult to consider at the same time. Due to the fact that pathological cell sedimentation sensitive parameter modeling and layered centrifugation safety parameter interval control are introduced, self-adaptive adjustment and result verification in the layered centrifugation process are achieved, and therefore pathological cells are prevented from being removed by mistake or damaged by excessive centrifugation.

This invention relates to the fields of analytical detection and online solid-phase extraction technology, specifically to a rapid detection method for trace plasma samples used in pharmacokinetic studies. The method first measures the empty baseline pressure; after injection, it calculates the net sample pressure and total resistance integral in real time, and identifies the transition point from injection to cleaning to lock the fluid dynamics boundary parameters; during the cleaning phase, it calculates the measured pressure decay rate and extrapolates the theoretical pressure decay rate under ideal emptying conditions, uses the total resistance integral to compensate for viscosity at the measured rate, and then obtains the flow hysteresis ratio characterizing the sample matrix retention effect based on both; finally, it uses the flow hysteresis ratio to adaptively correct a standard threshold to obtain a target threshold, and performs flow path switching when the measured rate reaches the target. This invention effectively decouples sample viscosity from adsorption characteristics, enabling adaptive adjustment of the cleaning time based on real-time sample kinetic feedback, completely eliminating matrix residue contamination while ensuring the recovery rate of polar drugs.

The invention discloses a cosmetic viscosity detection device which comprises a bottom plate, a stand column and a detection table are arranged on the bottom plate, a detection rack is arranged on the stand column, a sample table, a cleaning assembly, a disinfection assembly, an air drying assembly and a driving assembly are arranged on the detection table, the detection rack comprises a sliding frame, and the sliding frame is in sliding connection with the stand column. A machine box and a driving box are arranged on the sliding frame, a rotating main shaft is arranged at the lower end of the machine box, and the rotating main shaft is fixedly connected with a rotor. According to the technical key points, a driving assembly drives a stand column to rotate relative to a detection table and a bottom plate so as to drive a tail end rotor to rotate, and after sample viscosity detection is completed, the driving assembly drives the rotor to sequentially move to a cleaning area of a cleaning assembly, a disinfection area of a disinfection assembly and an air drying area of an air drying assembly; and automatic cleaning, disinfection and air drying of the rotor are achieved, and the rotor does not need to be disassembled, manually cleaned, wiped and then reinstalled.