Immunoaffinity column operating device

Abstract

The invention relates to improvement of a liquid chromatogram pretreatment instrument, in particular to an immunoaffinity column operating device. A solution tray is located on the rear part of the top end of a case, and thus the space for storing a solution bottle is omitted; and a cleaning pool is located at the front end of the case, a part of the cleaning pool is used for storing sample bottles and recovery bottles, and the other part of the cleaning pool serve as a cleaning part used for an injection needle. The cleaning part is provided with a corresponding cylindrical hole according tothe position of the injection needle, the injection needle is directly put into the hole when cleaned, and the inner wall and the outer wall of the needle are cleaned simultaneously. The problems thatas for an existing immunoaffinity column, the operation mode is long in time, the flow rate of liquid is uncontrollable, and the influence of sample viscosity and cleanliness is large are solved; andaccording to the immunoaffinity column operating device, multiple channels are formed, the flow rate of the liquid can be controlled, positive-pressure sample feeding is achieved, the sample recoveryrate is high, stable and consistent, a pipeline can be cleaned, and the low-residual effect is achieved.

Description

technical field [0001] The invention relates to an improvement of a liquid chromatography pretreatment instrument, in particular to an immunoaffinity column operating device. Background technique [0002] Immunoaffinity Chromatography (IAFC) Immunoaffinity chromatography uses one of the antigens and antibodies as a separation system for ligand affinity adsorption and the other is called immunoaffinity chromatography. [0003] The existing operating device of the immunoaffinity column is connected to the top of the affinity column through the syringe needle, and then the connected two parts are fixed on the bracket, and the sample and the required eluting solution flow through the liquid by its own weight. Affinity column, this operation method takes a long time, the liquid flow rate is uncontrollable, and is greatly affected by the viscosity and cleanliness of the sample. It is not allowed to pass the solution through the affinity column multiple times, and the sample recove...

AI Technical Summary

Problems solved by technology

[0003] The existing operating device of the immunoaffinity column is connected to the top of the affinity column through the syringe needle, and then the connected two parts are fixed on the bracket, and the sample and the required eluting solution flow through the liquid by its own weight. Affinity column, this operation method takes a long time, the liquid flow rate is uncontrollable, and is greatly affected by the viscosity and cleanliness of the sample. The solution cannot be passed through the affinity column multiple times, and the sample recovery rate is greatly different due to human intervention.

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