35 results about "Optical coherence elastography" patented technology

The invention discloses a detection device capable of integrating stimulated Brillouin scattering and optical coherent elastic imaging. The detection device comprises a stimulated Brillouin scatteringmeasuring branch and an optical coherent elastic imaging measuring branch. Single longitudinal mode horizontal polarized light is output by a laser, passes through a polarizing beam splitter and a quarter-wave plate sequentially and then is changed into circularly polarized light, the circularly polarized light is reflected by a totally reflecting mirror and is focused into a sample by a lens tostimulate stimulated Brillouin scattering, a scattered signal returns along a back direction by the phase conjugate characteristic, passes through the quarter-wave plate again, is changed into vertical polarization, is reflected by the polarizing beam splitter and the totally reflecting mirror and then passes through a lens, a filter and an F-P standard tool sequentially, and an ICCD signal acquisition system acquires a stimulated Brillouin scattering signal. The detection device has the following advantages: a fingerprint identification database for different sample detection is established by combining absorption spectral features corresponding to different detection samples as well as the bulk modulus, the shear elasticity and the viscosity information of the samples, and an effective method and technology for rapidly detecting various samples is formed finally.

The invention provides a Brillouin scattering and optical coherent elastic imaging in-situ detection method. According to the method, a wavelength division multiplexing method and a confocal optical path are adopted to integrate a Brillouin scattering elastic imaging system and an optical coherent elastic imaging system, then the two detection systems can perform imaging detection without mutual influences through a time sequence control system of a computer, and therefore in-situ detection of a bulk elasticity modulus and a shear elasticity modulus of a sample can be completed under the condition of not moving the sample. The method has the advantages that comparative research of the two elasticity moduli can provide technical support for diagnosis and early prevention of numerous clinical diseases; and the method has important significance and value for diagnosis, treatment and prevention of multiple clinical diseases currently and especially multiple eye diseases.

The invention discloses an optical coherence elastography (OCE) device. The device induce vibration by using ultrasound beams in a sample, vibration in the sample is detected by an imaging device, coupling of a detection light beam and the ultrasound beam is realized through a coupling unit, particularly, the coupling unit comprises a sound reflection surface and a light incidence surface, the sound reflection surface has an optical transparency characteristic and a sound reflection characteristic, so that the detection light beam from the light incidence surface can be transmitted to the to-be-detected sample through the light incidence surface and the sound reflection surface, the ultrasound beam from the light incidence surface is reflected by the sound reflection surface and then transmitted to the to-be-detected sample with the detection light beam in the same direction, same-side incidence of the ultrasound beam and the detection light beam is realized, and the vibration detection sensitivity can be improved. Besides, the device requires no preparation of an annular ultrasound transducer, cannot limit the spreading range of the detection light beam or ultrasound, and bad effects of weaker sound field intensity or light field intensity on the detection sensitivity are avoided.

Retinal diseases, such as age-related macular degeneration (AMD), are the leading cause of blindness in the elderly population. Since no known cures are currently present, it is crucial to diagnose the condition in its early stages so that disease progression is monitored. Systems and methods for detecting and mapping the mechanical elasticity of retinal layers in the posterior eye are disclosed herein. A system including confocal shear wave acoustic radiation force optical coherence elastography (SW-ARF-OCE) is provided, wherein an ultrasound transducer and an optical scan head are co-aligned to facilitate in-vivo study of the retina. In addition, an automatic segmentation algorithm is used to isolate tissue layers and analyze the shear wave propagation within the retinal tissue to estimate mechanical stress on the retina and detect early stages of retinal diseases based on the estimated mechanical stress.

The invention relates to a retina operation auxiliary device, in particular to a retina operation auxiliary device based on an optical coherence elastic imaging system. The technical problem to be solved is to provide the retina operation auxiliary device based on the optical coherence elastic imaging system, which can automatically open eyelids of a patient and can fix the body of the patient. The retina operation auxiliary device based on the optical coherence elastic imaging system comprises a supporting bed board, a positioning bottom frame, a buffering hinge frame, a damping bed board, a sponge mat and the like, the buffering hinge frame is arranged on the upper portion of the positioning bottom frame in a sliding mode, and the supporting bed board is rotationally arranged on the upper portion of the buffering hinge frame, a damping bed plate is arranged inside the supporting bed plate. Through cooperation of the driving mechanism and the limiting mechanism, the shoulder of a patient can be fixed, medical staff can conveniently conduct a cornea operation on the patient, and the situation that the operation is affected due to movement of the upper body of the patient is avoided.

The proposed combination device combines any tonometric metrology with a drug application to administer glaucoma medication on an eye. Several technical concepts are proposed and exemplary embodiments for rebound tonometry and air-puff tonometry are shown. However other methods such as optical coherence elastography (OCE) could also be used. The Solutions provide home care tonometry offerings which host the capability to administer glaucoma medication.

The invention relates to a device for measuring intraocular pressure, in particular to a device for measuring the intraocular pressure based on optical coherence elastography. The device for measuring the intraocular pressure based on the optical coherence elastography has the advantages that the measurement precision is high, the deformation of eyes can be refracted to an elastography photo when gas is sprayed to the eyes, and accurate data of the intraocular pressure can be more intuitively seen. The device for measuring the intraocular pressure based on the optical coherence elastography comprises bottom feet and a fixing frame, the bottom feet are arranged at the four corners of the bottom of the fixing frame, and the fixing frame is of a left-right hollow structure. Through the principle of elastography, information refracted by the eyes is converted into a visible light image, namely an imaging picture, which is habitual to a doctor, then a broadband light source is refracted to the imaging picture, and the visible light image and the imaging picture are overlapped, so that the doctor can judge an intraocular pressure result through the imaging picture.

The invention relates to a corneal removal amount device, in particular to a device for evaluating the corneal removal amount in a refractive operation through optical coherence elastography. The technical problem of the invention is to provide the device for evaluating the corneal removal amount in the refractive operation through optical coherence elastography, which can fix the position of a lens and can prevent the cornea of a patient from being hurt by too strong light. The device for evaluating the corneal removal amount in the refractive operation through optical coherence elastography comprises a first supporting framearranged on one side of a fixing frame and the fixing frame, a concave mirror frame arranged on the first support frame in a sliding manner, and a convex mirror frame arranged on the first support frame in a sliding manner and arranged on one side of the concave mirror frame. Through cooperation of the concave mirror frame, the convex mirror frame, a shading mechanism and a buffer mechanism, the medical staff can detect the cornea thickness of a patient more conveniently, external light can be shielded, and the detection result is more accurate.

The invention relates to a detection device, in particular to a three-dimensional optical coherence elastography detection device applied to a corneal refractive operation. The invention aims to provide the three-dimensional optical coherence elastography detection device applied to the corneal refraction operation, the device can prevent a convex lens from being contaminated by impurities and is relatively high in working efficiency. The three-dimensional optical coherence elastography detection device applied to the corneal refraction operation comprises a detection box body, buffer bases, a shading cover plate, a protection cover and a start button. The multiple buffer bases are arranged at the bottom of the detection box body at intervals, the shading cover plate is arranged on one side of the top of the detection box body, the protection cover is arranged on one side of the detection box body, and the start button is arranged on one side of the upper portion of the detection box body. According to the three-dimensional optical coherence elastography detection device applied to the corneal refraction operation, through cooperation of a material conveying mechanism and a detection mechanism, a convex lens can be automatically conveyed and subjected to light transmittance detection, people do not need to hold the convex lens with hands, and light transmittance detection is prevented from being affected.

The invention relates to a device for detecting crystalline lens elasticity imaging, in particular to a device for detecting crystalline lens elasticity through optical coherence elastography The device for detecting crystalline lens elasticity through optical coherence elastography is good in comfort level and accurate in detection result. The device for detecting elasticity of crystalline lens through optical coherence elastography comprises a base, first sliding rods, a sliding block, a first support, a first sliding sleeve, a connecting block, a hollow frame, a mark block and a marking rod, the first sliding rods are symmetrically arranged on the base, the sliding block is slidably connected between the upper portions of the two first sliding rods, and the first support is arranged on the upper portion of the sliding block; a first sliding sleeve is arranged on the upper portion of the sliding block, a marking rod is slidably connected between the first support and the first sliding sleeve, a hollow frame is arranged on the upper portion of the first support, and a marking block is slidably arranged in the hollow frame. By arranging the buffering mechanism, the comfort degree of crystalline lens elasticity detection is improved.

The invention relates to cornea three-dimensional detection equipment, and particularly relates to cornea three-dimensional detection equipment based on an optical coherence elastography principle. The cornea three-dimensional detection equipment based on the optical coherence elastography principle is easy to operate, the working mode is optimized, and therefore the labor cost is reduced; meanwhile, the position of a lens can be adjusted, and the equipment is suitable for various eye distances. The cornea three-dimensional detection equipment based on the optical coherence elastography principle comprises a main frame, a switch key, an imager, guide pipes and a sliding mechanism, the sliding mechanism is arranged on the upper portion of the main frame, the starting switch key is arranged on the sliding mechanism, the imager is arranged in the sliding mechanism in a sliding mode, and the guide pipes are symmetrically arranged on the sliding mechanism in a sliding mode. A permanent magnet is attracted to a limiting block, and therefore the opening state of a display screen is fixed; in cooperation with reading and observation of data, after the equipment is used, the display screen can be pushed to rotate and be recycled, and the display screen is prevented from being collided and damaged.