Optical coherent elastic imaging method and device

An elastography and optical coherence technology, applied in measurement devices, material analysis through optical means, scientific instruments, etc., can solve the problem of inability to comprehensively and accurately evaluate the anisotropic elastic characteristics of biological tissues and obtain axial elastic information and other issues to achieve a comprehensive and accurate assessment

Active Publication Date: 2020-07-28
BEIJING INFORMATION SCI & TECH UNIV
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Problems solved by technology

[0004] However, in the prior art, when the ultrasonic beam-induced optical coherent elastography method is used to image biological tissue, only the lateral elastic information of the measured biological tissue perpendicular to the external force direction can be obtained, but the measured biological tissue cannot obtain the Axial elastic information in the direction of external force, resulting in the inability to comprehensively and accurately evaluate the anisotropic elastic characteristics of biological tissues

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  • Optical coherent elastic imaging method and device
  • Optical coherent elastic imaging method and device
  • Optical coherent elastic imaging method and device

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Embodiment Construction

[0047]As mentioned in the background technology, when the ultrasonic acoustic beam-induced optical coherence elastography method in the prior art is used to image biological tissues, it can only obtain the lateral elasticity information of the measured biological tissue in the direction of vertical external force, but cannot obtain the measured biological tissue. The axial elastic information of biological tissue parallel to the direction of external force, the specific reason will be explained below.

[0048] When measuring the elasticity of biological tissue, first use external force to induce elastic waves in the tissue, then detect the propagation of elastic waves through the imaging platform, and finally calculate the elastic modulus in the direction of elastic wave propagation according to the propagation speed of elastic waves. Therefore, in the elastic measurement of anisotropic biological tissue, the construction of the elastic wave imaging platform is the basis of the...

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Abstract

The invention discloses an optical coherent elastic imaging method and a device. The optical coherent elastic imaging method uses an ultrasonic sound beam to induce a sample to be tested to generate afirst elastic wave and a second elastic wave perpendicular to a vertical propagation direction, so that when the optical coherence tomography method is used for imaging the first elastic wave and thesecond elastic wave, an imaging result containing elastic information in the first direction and the second direction can be obtained, so that the elastic information of the to-be-tested sample in the first direction and the elastic information of the to-be-tested sample d in the second direction can be obtained according to the imaging result, the purpose of measuring the axial and lateral elastic information of the tested sample is realized, and the purpose of comprehensive and accurate evaluation of the anisotropic elastic characteristics of the tested sample is realized.

Description

technical field [0001] The present application relates to the field of imaging technology, and more specifically, to an optical coherent elastography method and device. Background technique [0002] The difference in the elastic mechanical properties of biological tissues comes from the differences in the composition, structure and interaction of biomolecules, cells and samples. The measurement of the elasticity of biological tissues is of great significance for evaluating the physiological functions of samples, and can be used for eyeball, cardiovascular, breast, etc. , liver and other parts of the disease diagnosis. Age-related macular degeneration (AMD), a degenerative disease of the pigment epithelium in the macular area of ​​the retina, is one of the main causes of irreversible blindness in people over 60 years old. Retinal elasticity measurement can be used for risk assessment and early diagnosis of wet AMD, so as to achieve early intervention and treatment, so as to ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B8/00G01N21/84G01N29/04
CPCA61B5/0066A61B8/485A61B8/488A61B8/4483A61B8/4488G01N29/041G01N21/84
Inventor 朱疆樊凡祝连庆杨强王重阳
Owner BEIJING INFORMATION SCI & TECH UNIV
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