Traumatic rheumatism plaster and preparation method thereof

Abstract

The invention discloses a traumatic rheumatism plaster which comprises an ointment and a medicinal plaster matrix. The ointment comprises traumatic rheumatism liquid extract which is prepared from flos carthami, radix saposhnikoviae, rhizoma zingiberis, unprocessed radix aconiti kusnezoffii, herba schizonepetae, unprocessed radix aconiti, radix angelicae, herba glechomae, rhizoma kaempferiae and unprocessed semen strychni. Volatile oil is extracted from medicine by adopting supercritical CO2 extraction technology in the preparation process, so that volatile oil extraction rate is increased, and damage to active ingredients is reduced; a volatile medicine inclusion compound is prepared by adopting inclusion technology, so that loss of volatile active ingredients in the process of preparing and storing a musk traumatic rheumatism plaster is reduced, and medicine efficacy is improved; a novel hydrophilic matrix is adopted, so that environment pollution caused by an organic solvent is avoided, allergic reaction which is prone to appearing in the process of medication is reduced, medication compliance of patients is improved, and the traumatic rheumatism plaster has remarkable treatment effect on rheumatism, swelling and joint pain.

Description

technical field [0001] The invention relates to a plaster, in particular to a Dieda Rheumatism plaster and a preparation method thereof. Background technique [0002] Volatile oils (VO), also known as essential oils, are a general term for a class of oily liquids that are volatile and immiscible with water that exist in plants. The volatile oil has the characteristics of strong lipophilicity and low boiling point. In the preparation method of Dieda Rheumatism Plaster on the market, the volatile oil mainly adopts the solvent extraction method. The commonly used solvents in the solvent extraction method are petroleum ether, diethyl ether, and carbon tetrachloride. Etc. Medicinal materials such as Nepeta, Kaevil and Dried Ginger are usually extracted by adding 90% ethanol and heating under reflux. The polarity of 90% ethanol is too high to fully extract the volatile oil in Schizonepeta, Kaevil and Dried Ginger. At the same time, the temperature of the extraction process is high...

AI Technical Summary

Problems solved by technology

The volatile oil has the characteristics of strong lipophilicity and low boiling point. In the preparation method of Dieda Rheumatism Plaster on the market, the volatile oil mainly adopts the solvent extraction method. The commonly used solvents in the solvent extraction method are petroleum ether, diethyl ether, and carbon tetrachloride. Etc. Medicinal materials such as Nepeta, Kaevil and Dried Ginger are usually extracted by adding 90% ethanol and heating under reflux. The polarity of 90% ethanol is too high to fully extract the volatile oil in Schizonepeta, Kaevil and Dried Ginger. At the same time, the temperature of the extraction process is high. , the extraction time is long, it is easy to cause damage to thermally unstable and easily oxidized components, which is not conducive to exerting the curative effect of the drug

In the preparation method of Dieda Fengshi Plaster currently on the market, the volatile oil is directly mixed with the matrix material to make a coating, and the paste is applied, cut into sections, covered with lining, and cut into pieces, which will easily cause the loss of volatile components and reduce the curative effect of the medicine.

The traditional rubber agent uses gasoline pulp, which is not conducive to environmental protection, and it is painful to peel off after use, prone to allergic reactions, and patients' medication compliance is poor

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