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Extractive of pomegranate seeds, prepn. method and application in preparing medicine thereof

A pomegranate seed extract and a technology of pomegranate seeds are applied in the field of extracts of natural plants, and can solve the problems of unreasonable utilization of pomegranate seeds, no reports on the preparation method for medicinal properties of pomegranate seed oil, and waste of resources.

Inactive Publication Date: 2006-06-14
HUAZHONG UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to reports, the pomegranate seed kernel rate is 29.9%, and the pomegranate seed kernel oil content rate is as high as 50.9%, and has very high dietary value; however, the medicinal properties and preparation methods of pomegranate seed oil have not been reported yet.
Pomegranate seeds discarded after deep processing of pomegranates cannot be rationally utilized, resulting in a waste of resources

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] 100g of pomegranate seeds were washed, ventilated and dried, crushed, put the pomegranate seed powder into a 500ml round bottom flask, added 120ml of petroleum ether, put the flask into a microwave oven with a power of 320w, intermittent treatment for 210s (radiation 3 times, 70s each time), and took out Filter with a suction filter bottle. The filtrate was recovered with a vacuum rotary evaporator: vacuum degree -0.02Mpa, temperature 30°C. Petroleum ether was recovered to obtain 11 g of pomegranate seed oil, gas chromatography detection: 66.6% punicic acid; 10.0% linoleic acid, 9.5% stearic acid, 4.7% palmitic acid, 9.2% oleic acid.

Embodiment 2

[0058] 100g of pomegranate seeds were washed, ventilated and dried, crushed, put the pomegranate seed powder into a 500ml round bottom flask, add 300ml of n-hexane, put the flask into a microwave oven, adjust the power to 160w, and radiate intermittently for 250s (radiation 5 times, 50s each time). Take out and filter with a suction filter bottle. The filtrate was recovered with a vacuum rotary evaporator: vacuum degree -0.05Mpa, temperature 45°C. Petroleum ether was recovered and 12.5 g of pomegranate seed oil was obtained. Gas chromatography detection: 71% punicic acid; 10% linoleic acid, 7.5% stearic acid, 4.5% palmitic acid, 7.0% oleic acid.

Embodiment 3

[0060] 100g of pomegranate seeds were washed, ventilated and dried, crushed, put the pomegranate seed powder into a 500ml round bottom flask, added 420ml of ether, put the flask into a microwave oven, adjusted the power to 600w, intermittently irradiated for 90s (radiation 8 times, 30s each time), and took it out Suction filter bottle to filter. The filtrate was recovered with a vacuum rotary evaporator: vacuum degree -0.08Mpa, temperature 40°C. Petroleum ether was recovered and 11.6 g of pomegranate seed oil was obtained. Gas chromatography detection: 65.5% punicic acid; 9.7% linoleic acid, 10.0% stearic acid, 5.0% palmitic acid, 9.8% oleic acid.

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PUM

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Abstract

An extract of pomegranate seed for preparing the medicines or health-care food to prevent and treat hyperlipemia and tumor contains punicic acid (65-95 Wt%), linoleic acid (1-10), stearic acid (1-10), palmic acid (2-5) and oleic acid (1-10). Its preparing process includes such steps as washing pomegranate seeds, drying, crushing, and extracting in organic or by supercritical extraction.

Description

technical field [0001] The invention belongs to natural plant extracts, in particular to a natural plant seed extract, its preparation method and its application in the preparation of medicine or health food. Background technique [0002] Pomegranate (Punica granatuml) belongs to the Pomegranate family and has been a medicinal and edible plant since ancient times. Its peel, petals and leaves can be used as medicine. Pomegranate peel has been recorded in all previous editions of Chinese Pharmacopoeia. Existing pharmacological studies have shown that it has unique activities such as preventing and treating sexually transmitted diseases, antibacterial, antiviral, and anticancer; ursolic acid and sitosterol in pomegranate flowers are used as astringent Pomegranate flower extract can significantly reduce blood sugar in rats; pomegranate leaf extract can significantly increase cerebral microcirculation blood flow in rats. According to reports, the pomegranate seed kernel rate is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A23L33/105A23L33/12A61P35/00A61P39/06
Inventor 敖明章余龙江李文敏
Owner HUAZHONG UNIV OF SCI & TECH
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