The invention relates to the pesticide field and discloses cockroach plant-source pesticide bait which is mainly made from tea saponin and boric acid. Particularly, the cockroach plant-source pesticide bait is prepared from tea saponin, boric acid, fried soybean meal, potassium sorbate, glycerine, vaseline, xanthan gum and sesame oil. The preparation method of the high-efficiency low-toxicity low-cost pesticide bait comprises the following steps: grinding, screening, sitrring, dissolving and filling. The raw materials of the pesticide bait are all green, environmentally friendly and pollution-free. The product has high efficiency and low toxicity, is convenient to use, has low cost, small dosage, and obvious insecticidal effect on cockroach including German cockroach, moreover, the materials of the cockroach plant-source pesticide bait are easy to obtain. When the two main raw materials, namely tea saponin and boric acid, are in the optimal proportion, the corresponding co-toxicity coefficient (CTC) is up to 128. The product can meet the cockroach-killing demands of places such as domiciles, office buildings, warehouses and restaurants.