Preparation method of hydrogel medical dressing for promoting wound healing

A technology of hydrogel medicine and wound healing, which is applied in the field of preparation of mixed hydrogel dressings, can solve problems such as destruction, accelerated wound healing, and secondary pain for patients, and achieves simple process, increased targeting efficiency, and low price Effect

Active Publication Date: 2019-05-31
TAIYUAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Medical dressing is a kind of biomedical material used to treat sores, wounds and other skin lesions. It is widely used in daily life. During the reconstruction or recovery period of skin trauma, medical dressing can temporarily play part of the function of skin barrier and promote wound healing. To provide a favorable microenvironment, medical dressings have important functions such as physical barriers, controlling wound secretions and odors, controlling wound infection, hemostasis, reducing or removing scar formation, and accelerating wound healing. Hydrogel medical dressings are A new type of wound dressing developed in recent years is mainly composed of high-molecular polymers that absorb water and swell to form a gel

Method used

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  • Preparation method of hydrogel medical dressing for promoting wound healing
  • Preparation method of hydrogel medical dressing for promoting wound healing
  • Preparation method of hydrogel medical dressing for promoting wound healing

Examples

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Comparison scheme
Effect test

Embodiment 1

[0033] Implement a kind of preparation method for the hydrogel medical dressing that is used to promote wound healing, and this preparation method is carried out according to the following steps:

[0034] Step 1: Weigh 2g of polyvinyl alcohol on weighing paper, put it into 50ml of deionized water, and prepare a 40mg / ml PVA solution. Continue heating and stirring at a high temperature of 90°C for 30 minutes to completely dissolve until clear.

[0035] Step 2: Accurately weigh 0.483g of copper nitrate and dissolve in 25ml of dimethyl sulfoxide solution to form a blue clear solution, add 0.4g of PVP and 0.3g of thioacetamide, and stir magnetically for a period of time until the mixed solution turns light green. The solution was transferred into a 30ml polytetrafluoroethylene reaction kettle, heated with hydrothermal heat, and then the heated solution was centrifuged and dried to obtain CuS nanostructures.

[0036] Step 3: Dissolve 0.75g sodium molybdate and 1.5g thioacetamide in...

Embodiment 2

[0039] Implement a kind of preparation method for the hydrogel medical dressing that is used to promote wound healing, and this preparation method is carried out according to the following steps:

[0040] Step 1: Weigh 2g of polyvinyl alcohol on weighing paper, put it into 50ml of deionized water, and prepare a 40mg / ml PVA solution. Continue heating and stirring at a high temperature of 90°C for 30 minutes to completely dissolve until clear.

[0041] Step 2: Accurately weigh 0.483g of copper nitrate and dissolve in 25ml of dimethyl sulfoxide solution to form a blue clear solution, add 0.4g of PVP and 0.3g of thioacetamide, and stir magnetically for a period of time until the mixed solution turns light green. The solution was transferred into a 30ml polytetrafluoroethylene reaction kettle, heated with hydrothermal heat, and then the heated solution was centrifuged and dried to obtain CuS nanostructures.

[0042] Step 3: Dissolve 0.75g sodium molybdate and 1.5g thioacetamide in...

Embodiment 3

[0045] Implement a kind of preparation method for the hydrogel medical dressing that is used to promote wound healing, and this preparation method is carried out according to the following steps:

[0046] Step 1: Weigh 2g of polyvinyl alcohol on weighing paper, put it into 50ml of deionized water, and prepare a 40mg / ml PVA solution. Continue heating and stirring at a high temperature of 90°C for 30 minutes to completely dissolve until clear.

[0047] Step 2: Accurately weigh 0.483g of copper nitrate and dissolve in 25ml of dimethyl sulfoxide solution to form a blue clear solution, add 0.4g of PVP and 0.3g of thioacetamide, and stir magnetically for a period of time until the mixed solution turns light green. The solution was transferred into a 30ml polytetrafluoroethylene reaction kettle, heated with hydrothermal heat, and then the heated solution was centrifuged and dried to obtain CuS nanostructures.

[0048] Step 3: Dissolve 0.75g sodium molybdate and 1.5g thioacetamide in...

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PUM

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Abstract

Provided is a preparation method of a hydrogel medical dressing for promoting wound healing. The preparation method comprises the steps of firstly preparing a reddish-brown CuS@MoS2 composite structure by a hydrothermal method, then uniformly doping the red-brown CuS@MoS2 composite structure into a polyvinyl alcohol solution, and forming CuS@MoS2 hydrogel after several freeze-thawing cycles to prepare a dressing for promoting wound healing. The preparation method is simple, the production cost is low, the repeatability is good, and satisfactory results are obtained by applying the dressing tolarge area scalds, burns and other wounds which are not easy to heal.

Description

technical field [0001] The invention relates to a preparation method of wound healing dressing, especially a method using photothermal method and CuS@MoS 2 Preparation method of hybrid hydrogel dressing with hydrogel synergistically antibacterial and promoting wound healing. Background technique [0002] Bacterial infectious diseases account for one-third of the global mortality rate. According to reports, 25,000 people in Europe die due to bacterial infections every year. In the treatment of bacterial infectious diseases, the European Union invests 1.5 billion euros every year. As we all know, skin tissue is the body's own defense against the outside world. An important barrier to environmental infection, so avoiding skin tissue from bacterial infection and accelerating wound healing of damaged skin tissue is a very urgent task, currently antibiotic-based therapy is the most common way to treat infection, but excessive use of antibiotics will Lead to enhanced bacterial res...

Claims

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Application Information

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IPC IPC(8): A61L26/00A61K41/00A61K9/06A61P17/02A61P31/02A61P31/04
Inventor 张翔宇张星宇柴茂洲刘小萍姚晓红唐宾
Owner TAIYUAN UNIV OF TECH
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