The invention relates to a plastic-wood composite material which is characterized by comprising a main material and an auxiliary material, wherein the main material comprises waste plastic and biomass fibers; the auxiliary material comprises a lubricant, a compatilizer, a stabilizer, a dispersant, a coupling agent and an antioxidant; the main material also comprises cement, fly ash and natural stone powder. The plastic-wood composite material has the advantages of high compression resistance, high impact resistance, favorable acid/alkali resistance, favorable high/low-temperature resistance, favorable heat-insulating property, favorable wear resistance, favorable elasticity, favorable aging resistance, long service life and the like, can comprehensively utilize waste materials, is environment-friendly, and can be used for making various articles or appliances instead of wood, plastic and stone. The invention also provides a manufacturing method of the plastic-wood composite material, which is scientific and reasonable in technique, and is easy for formation.