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95results about How to "Accelerate the degradation rate" patented technology
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Integral engineering rack of interface osteochondro tissue with bionic function
InactiveCN101020083AIncrease connection areaImprove connection strengthJoint implantsSubchondral boneBiocompatibility Testing
Owner:THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
Urban domestic sewage treatment process and its method
InactiveCN1412134AReduce contentReduce concentrationWater/sewage treatmentMultistage water/sewage treatmentWater qualitySmall footprint
The city sewage treatment process includes the following steps: utilizing grile and desilting basin to pretreat sewage, adding coagulating agent to make the phosphorus, heavy metal and orgnaic matters existed as colloid and suspended substances feed into anaerobic reactor in the form of sludge to make organic matter convert into impure methane, making the supernatant fluid pass through the next aerobic treatment reactor to remove organic matter and convert the ammoniacal nitrogen into nitric nitrogen, mixing anaerobic discharged water and aerobic discharged water, and making the mixture waterundergo the process of anaerobic treatment to make denitrifcation, finally utilizing secondary aeration and precipitation to completely remove organic matters from sewage so as to attain the goal of cleaning the sewage.
Owner:NANKAI UNIV
Preparation of hyaluronic-acid-based double-targeting nano-composite medicament and application of double-targeting nano-composite medicament
InactiveCN103143027AHigh mechanical strengthAccelerate the degradation rateOrganic active ingredientsPharmaceutical non-active ingredientsTumor targetDispersity
The invention relates to a hyaluronic-acid-based double-targeting nano-composite medicament and a preparation method thereof. Hydrophobic group ursodeoxycholic acid is included in a hyaluronic acid nano-polymer structure and can form an amphipathic polymer and automatically generate micelles in an aqueous solution, and polyethylene glycol can be introduced into the micelles to improve the dispersity and stability of a composite. An anti-tumor medicament can enter a nano-carrier through electrostatic adsorption or physical inclusion to generate a nano-medicament composite, wherein the nano-medicament composite is selectively concentrated in a tumor cell under an active targeting effect of hyaluronic acid and a surface CD44 receptor of a tumor cell, and promotes a tumor tissue to absorb the nano medicament-carrying composite by using a passive osmotic accumulation effect (EPR) at the same time. After an anti-tumor medicament is wrapped by a modified hyaluronic acid polymer, the anti-tumor medicament has the advantages of improving the bioavailability of the medicament, improving the targeting property, reducing the toxic and side effects, prolonging the half-life period of the medicament, being stably stored and the like, so that the tumor targeting therapy efficiency is improved in many ways.
Owner:XIAMEN UNIV
Biodegradable composite film material of controllable degradation rate and preparation method thereof
The invention aims to provide a biodegradable composite film material of controllable degradation rate with good mechanical property, faster and more through degradation and no environmental harm, and a preparation method thereof. The material comprises the following components in parts by weight: 100 parts of matrix resin, 0-40 parts of other biodegradable polymers, 0.5-1.5 parts of heat stabilizer, 0.3-5 parts of nucleating agent, 1-5 parts of compatilizer, 2-15 parts of plasticizer and 0.3-5 parts of opener. The matrix resin is obtained by mixing poly lactic acid (PLA) and 3-hydroxybutyrate-3-hydroxy acid copolyester (PHBH) with each 20-80 parts by weight. The other biodegradable polymers are poly butylenes succinate (PBS), poly propylene carbonate (PPC), 3-hydroxybutyrate-3-hydroxyvalerate copolyester (PHBV) and terephthalic acid-butanediol-adipic acid copolyester (PBAT).
Owner:BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
Preparation method of composite nanometer fiber small-diameter intravascular tissue engineering stent material
InactiveCN101653624AGood physical and mechanical propertiesGood chemical stabilityStentsProsthesisFiberCell adhesion
The invention relates to the field of tissue engineering, in particular to a preparation method of a composite nanometer fiber small-diameter intravascular tissue engineering stent material. The technical scheme is achieved as follows: formic acid is used as a common solvent; RGD-recombinant spider silk protein, polycaprolactone and chitosan are mixed in a mass ratio of 1:8:1 according to the requirements of an intravascular stent to prepare a spinning solution with the concentration of 20-30 percent (w / v); electrospinning process parameters are as follows: the diameter of a cross section of acylindrical rotating shaft is 3-6 mm, the rotating speed is 1,500-3,000rpm, the curing distance is 15-30 cm, the voltage is 50-150kV, the extrusion speed is 3-7ml / h and the temperature is 45-50 DEG C. The small-diameter intravascular stent has favorable cell adhesion-promoting capability, anticoagulant property and mechanical property for resisting physiological environment and can be clinicallyapplied as a small-diameter intravascular tissue engineering stent.
Owner:FUJIAN NORMAL UNIV
Zn-Ge-X ternary biomedical material and preparation method thereof
ActiveCN109966568AGood mechanical propertiesGood blood compatibilitySurgeryMechanical propertyMaterials science
The invention discloses a Zn-Ge-X ternary biomedical material and a preparation method thereof. The Zn-Ge-X ternary biomedical material comprises the following components in percentage by mass: 0.5-6wt% of Ge, 0.1-1wt% of X and the balance of Zn, wherein X is selected from at least one of Mg, Cu, Mn, Sr, Fe, Ca, Ag and Ti. The ternary Zn-Ge-X biomedical material prepared by adopting traditional casting and deformation treatment as the preparation method and through optimizing deformation treatment and the components of the ternary material has excellent mechanical properties, good cell compatibility and suitable biodegradability, and is expected to become a potential degradable biomedical material.
Owner:XIANGTAN UNIV
Biological affinitive hydrophilic modified magnetic filler
InactiveCN104192993AImprove hydrophilicityIncrease chance of contactSustainable biological treatmentBiological water/sewage treatmentPolyvinyl alcoholStearic acid
The invention relates to biological affinitive hydrophilic modified magnetic filler applied in the field of wastewater treatment. The biological affinitive hydrophilic modified magnetic filler comprises the following raw materials: 78%-82% of polypropylene, 6%-8% of polyvinyl alcohol, 2%-4% of active carbon powder, 2%-3% of modified heavy calcium carbonate powder, 2% of hydroxyapatite, 1.6% of stearic acid, 0.4% of white mineral oil and 4% of modified barium ferrite magnetic powder. According to the biological affinitive hydrophilic modified magnetic filler, a biological hydrophilic macromolecular material-polyvinyl alcohol is mainly introduced, so that the pollutant adsorption performance can be improved; the hydroxyapatite is introduced, so that the bioactivity can be improved, a proper nutritional source is provided for microorganisms, the hydrophilicity of the filler is improved, the biofilm formation starting speed is increased, and the wastewater treatment efficiency is improved; the modified barium ferrite magnetic powder containing rare metal is introduced, so that a microscopic high-intensity magnetic field and a macroscopic low-intensity magnetic field are formed, the adsorption effect of degradation bacteria on the surface of the filler is enhanced, and then the biofilm formation speed and the wastewater degradation speed of the filler in wastewater treatment are increased.
Owner:王伟
Preparation method and application of ordered mesoporous carbon-activated carbon fibrofelt composite material
ActiveCN102730801ALarge specific surface areaHigh pore volumeWater/sewage treatment by oxidationDyeing wastewaterOxygen
The invention relates to the technical fields of preparation and application of a novel massive carbon material with an ordered mesoporous structure, and particularly discloses a preparation method and application of an ordered mesoporous carbon-activated carbon fibrofelt composite material. The ordered mesoporous carbon-activated carbon fibrofelt (OMC-ACF) composite material disclosed by the invention is a novel massive carbon material with an ordered mesoporous structure, and is prepared by taking phenolic resin as a carbon source and F127 as a structure directing agent, coating the phenolic resin and the F127 on the surface of an ACF at the same time according to a certain proportion, and performing intermolecular self-assembly, thermal polymerization and calcination under the protection of an inert gas; and the composite material is large in specific area, high in pore volume and large in bore diameter, so that the composite material can be used as a novel electrode material. The novel massive carbon material prepared by the method has the advantages of high catalytic degradation activity, high stability and the like in a test of cathode diffusion oxygen degradation dye wastewater through electro-Fenton reaction; and the novel massive carbon material is simple in production process and low in cost, and can be easily industrialized.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
Preparation method of acellular dermal matrix material
InactiveCN109364298AClean up thoroughlyLow toxicityTissue regenerationProsthesisAntigenSplit skin graft
The invention discloses a preparation method of an acellular dermal matrix material. The preparation method of the acellular dermal matrix material is characterized in that removing flesh and hair from an animal skin, then taking a split-skin graft, and carrying out defatting, unhairing, inactivation of virus, cell extraction, crosslinking modification, cleaning and moisturizing, packing and irradiation sterilization processes to obtain the acellular dermal matrix material. The preparation method of the acellular dermal matrix material has the characteristics that the process time is short, aneffect of removing antigen substances is good, and the material has quite good adhering property, moisture retention property, breathability and the like.
Owner:JIANGYIN BENXIANG BIOTECHOLOGY
Hydrophilic poly-beta-hydroxybutyrate (PHB) fiber and preparation method thereof
InactiveCN102560740AOvercome brittlenessImprove poor hydrophilicityConjugated synthetic polymer artificial filamentsMethacrylic acid copolymerPolylactic acid
The invention discloses a hydrophilic poly-beta-hydroxybutyrate (PHB) fiber, which is prepared by blending and spinning the following raw materials in percentage by mass: 10 to 20 percent of hydrophilic polymer, 0 to 45 percent of polylactic acid (PLLA) and 40 to 80 percent of PHB, wherein the hydrophilic polymer is methacrylic acid copolymer, polyacrylic acid, polyacrylamide, polyethylene glycol, polyoxyethylene, polyvinyl alcohol or polyvinyl pyrrolidone. In addition, the invention also discloses a preparation method for the hydrophilic PHB fiber. By blending and spinning the PHB and the hydrophilic polymer, the brittleness of the PHB is overcome, the problems of poor hydrophilic property and long degrading period of the PHB fiber are solved, the toughness of the PHB fiber is improved, and the processing range of the PHB is widened. The preparation method is easy and convenient, the process conditions are simple and easy to control, and the tensile strength of the prepared hydrophilic PHB fiber at break can reach over 6.1cN / dtex.
Owner:杨青芳
Polylactic-acid-modified magnesium alloy medical composite material and preparation method thereof
ActiveCN107185032AGood biocompatibilityPromote degradationAnodisationPharmaceutical delivery mechanismMicro arc oxidationPlasma electrolytic oxidation
The invention relates to a polylactic-acid-modified magnesium alloy medical composite material and a preparation method thereof. The method comprises: 1) performing micro arc oxidation treatment on a surface of a magnesium alloy substrate, and performing coupling treatment to obtain a silicane coupling substrate; 2) adding a surfactant to a chitosan solution, and performing uniform mixing to obtain a chitosan mixed liquid, and dissolving polylactic acid in trichloromethane to prepare a polylactic acid solution, and adding the polylactic acid solution in the chitosan mixed liquid while performing stirring, and performing high speed emulsification to obtain a film-casting liquid; and 3) coating the surface of the silicane coupling substrate with the film-casting liquid, removing the solvent and the surfactant to obtain a dry film layer, and performing thermal insulation at 80-90 DEG C to obtain the composite material. The composite material is excellent in biological compatibility, surface activity and mechanical properties. The degradation rate of the material can be controlled by adjusting the thickness of a polylactic acid and chitosan film layer. After the material is implanted to a human body, the degradation product can be absorbed by the human body or excreted outside the body with metabolism, so that secondary operation is not required.
Owner:广州雄俊智能科技有限公司
Preparation method and application of municipal sludge derived self-doped iron and nitrogen species carbon material electrode
ActiveCN111646547ALow costReduce typesWater contaminantsWater/sewage treatmentSludgeMaterials science
The invention relates to the technical field of preparation and application of carbon materials, in particular to a preparation method of a municipal sludge derived self-doped iron and nitrogen species carbon material electrode and application of the municipal sludge derived self-doped iron and nitrogen species carbon material electrode as a cathode material to electro-Peroxone reaction to degradetoxic organic pollutants. Municipal sludge serves as a carbon material precursor, after one-step pyrolysis, an obtained carbon material is washed, filtered and dried, the carbon material, acetylene black powder and polytetrafluoroethylene dispersion liquid are mixed and dissolved in an ethanol solvent according to a certain proportion, ultrasonic treatment, stirring, drying and pressing are carried out to form a film, a titanium mesh serves as a carrier for compounding, and the electrode is prepared. The material is self-doped with iron and nitrogen species, iron and nitrogen sources do not need to be additionally added, the preparation method is simple, the cost is relatively low, and the obtained product is more environmentally friendly. And when being used as a cathode material in degradation of toxic organic pollutants by an electric-Peroxone reaction, the composite material shows excellent catalytic degradation activity and degradation rate, and the efficiency of the composite material is far higher than that of a common carbon-based material.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
Degradation-controllable magnesium phosphate cement and preparation method and application thereof
ActiveCN105731990AEasy to operateHigh compressive strengthTissue regenerationProsthesisIonHydroxypropylmethyl cellulose
Provided are degradation-controllable magnesium phosphate cement and a preparation method and application thereof.The degradation-controllable magnesium phosphate cement is characterized by being prepared from, by mass, 35%-65% of magnesia powder, 15%-40% of monopotassium phosphate, 2%-7% of borax, 10%-25% of deionized water, 0%-1% of chitosan and 0%-1% of hydroxypropyl methyl cellulose.Compared with an existing material, the degradation-controllable magnesium phosphate cement is high in strength, good in biological activity and controllable in degradation rate and has a good application prospect in the field of biomedical materials by serving as a bone repair material.
Owner:HENAN POLYTECHNIC UNIV
Urea formaldehyde modifier as well as preparation method and application thereof
InactiveCN107857606AMolecular structure optimization and improvementAccelerate the degradation rateDi-calcium phosphate fertilisersAlkali orthophosphate fertiliserOrganic acidNitrogen
The invention relates to the technical field of modification treatment of urea formaldehyde used for slow-release fertilizers, and in particular relates to a urea formaldehyde modifier as well as a preparation method and application thereof. According to the method provided by the invention, an organic acid prepared by fermentation of starch is adopted as the urea formaldehyde modifier, and the organic acid is used for modification treatment of urea formaldehyde, wherein the organic acid makes nitrogen of the urea formaldehyde released quickly, makes the modified urea formaldehyde more suitable for the production of the slow-release fertilizers, and improves the quality of the slow-release fertilizers; and the added organic acid is obtained by fermentation of biomass components, a plurality of the biomass components are compounded in the organic acid, and after entering soil, the organic acid can effectively improve the soil and provide nutrients for crops.
Owner:GUIZHOU WUGUHUI ECOLOGICAL AGRI TECHCO +1
Preparation method for nano-TiO2 modified micro-channel reactor
ActiveCN104941553ASimple processIncrease channel densityWater/sewage treatment by irradiationEnergy based chemical/physical/physico-chemical processesIonChemistry
The invention provides a preparation method for a nano-TiO2 modified micro-channel reactor. The preparation method comprises the following steps: preparing a micro-channel reactor made of a transparent material, and cleaning the micro-channel reactor for later use; adding a titanium source in an acidic water solution or ammonia water to obtain a mixture, and stirring the mixture to form nano-TiO2 sol; injecting the nano-TiO2 sol in a channel of the later-use micro-channel reactor, staying for 5-30 min, and injecting deionized water in the channel of the micro-channel reactor for cleaning to obtain a nano-TiO2 sol particle modified micro-channel reactor; placing the nano-TiO2 sol particle modified micro-channel reactor in a 500-1,000 W infrared source to be illuminated, ultrasonically cleaning the passage with an acidic cleaning solution and deionized water in sequence, and obtaining the nano-TiO2 modified micro-channel reactor. The preparation method has the characteristics of being simple in preparation process, and easy to achieve industrial production; the micro-channel reactor, prepared according to the preparation method, has the characteristics of being high in density, convenient and high in efficiency.
Owner:QUZHOU UNIV
High-strength biomedical Mg-Zn-Zr-Fe alloy material with rapid biodegradability, and preparation method thereof
The invention discloses a high-strength biomedical Mg-Zn-Zr-Fe alloy material with rapid biodegradability, and a preparation method thereof. The magnesium alloy is prepared from the components in percentage by mass: 5.0 to 6.0 percent of Zn, 0.5 to 1.0 percent of Zr, 0.01 to 0.09 percent of Fe, and the balance Mg and inevitable impurities. The preparation method comprises the concrete steps of smelting, carrying out casting homogenization treatment, hot-extruding and carrying out artificial aging treatment, so that biomedical magnesium alloy sheets, rods and wires meeting the service requirement of the biological fluid environment are obtained. According to the high-strength biomedical Mg-Zn-Zr-Fe alloy material with rapid biodegradability provided by the invention, the alloy elements harmless to a human body are added into the magnesium alloy, so that the alloy has no any toxicity on the human body after being degraded in vivo, and has excellent mechanical property, favorable mechanical property and processability, and appropriate corrosion rate. The high-strength degradable biomedical Mg-Zn-Zr-Fe alloy material provided by the invention has the tensile strength being larger thanor equal to 360MPa and the yield strength being larger than or equal to 320MPa, and is suitable for preparing medical materials such as bone nails.
Owner:NEW MATERIAL INST OF SHANDONG ACADEMY OF SCI
Preparation method and application of humin acid based poly (lactic acid) crystallization nucleating agent and material
The invention relates to the technical field of poly (lactic acid) polymer materials, in particular to a preparation method and application of a humin acid based poly (lactic acid) crystallization nucleating agent and a poly (lactic acid) composite material. The humin acid based poly (lactic acid) crystallization nucleating agent is prepared from the humin acid, carbonyl diimidazole, hydrochloricacid, pyridine and amines. With the humin acid based poly (lactic acid) crystallization nucleating agent, mechanical property, heat resistance, crystallization performance and degradation velocity ofthe poly (lactic acid) composite material are obviously improved, the poly (lactic acid) composite material is excellent in mechanical property, heat resistance, crystallization performance and high in degradation velocity, and the application range of the poly (lactic acid) composite material can be well expanded due to the good mechanical property, degradation performance and heat resistance; the poly (lactic acid) composite material is prepared by using twin-screw extrusion equipment, so that simpleness in technology, short production circle and low production cost are achieved.
Owner:XINJIANG UNIVERSITY
Preparation method of cell substrate protein biological support material used for tissue engineering
A cytostromatic protein bioscaffold material for tissue engineering is prepared through using the buffering acetic acid solution to extract the cytostromatic protein, depositing with inorganic salt, and using the inorganic salt with different gradient to remove the III-type collagen from the cytostromatic protein, resulting in purified cytostromatic protein. Its advantages are high stability, purity and adhesion and no toxic by-effect.
Owner:STOMATOLOGICAL HOSPITAL NO 4 ARMY MEDICAL COLLEGE PLA +1
Hydroxyapatite/polyurethane porous bone repair material with shape memory
InactiveCN113368311AGood shape memory effectHigh porosityTissue regenerationProsthesisBiocompatibilityBiological materials
The invention relates to a biological material for bone injury repair. A hydroxyapatite / polyurethane porous bone repair material with shape memory is mainly prepared by a gas foaming method. The porous bone repair material with the shape memory function is prepared from polycaprolactone and polytetrahydrofuran which are equal in mass and hydroxyapatite in different proportions. The bone repair material shows a good shape memory effect at 37 DEG C, the shape recovery rate of the bone repair material can reach 100%, the bone repair material can change the shape in an extremely short time to fill a defect part, and the material can adapt to and gradually degrade along with repair closing of tissue growth. In addition, the bone repair material also has the advantages of high porosity, good biocompatibility, non-toxic and harmless degradation products and the like, the preparation method is simple, the cost is low, and an effective and feasible way is provided for preparing the hydroxyapatite / polyurethane porous bone repair material with shape memory for the field of biological materials.
Owner:CHENGDU UNIVERSITY OF TECHNOLOGY
Bone cement with induction and degradation characteristics and preparation method of bone cement with induction and degradation characteristics
InactiveCN108379652AAct as a mechanical supportImprove abilitiesTissue regenerationProsthesisBiocompatibility TestingBone growth
The invention belongs to the field of biological medical materials and particularly relates to bone cement with induction and degradation characteristics and a preparation method of the bone cement with the induction and degradation characteristics. The bone cement is made by powder and solidification liquid according to a ratio of 1:(0.3-1.2); the powder is prepared from, by mass, 30%-70% of calcium sulfate salt, 20%-60% of calcium phosphate salt, 0.1%-5% of inorganic additives, 0.1%-5% of organic additives and 0%-20% of DBM bone powder; the solidification liquid is phosphate solution. The bone cement is excellent in compressive strength, biocompatibility, bone conductivity and bone inductivity, and degradation speed of the bone cement is equivalent to bone growth speed. The bone cement can be made into different dosage forms by control of a liquid-solid ratio, injection products can be used for minimal invasive surgery and are great in collapse resistance, and paste products can be shaped arbitrarily to meet various demands of patients.
Owner:湖北联结生物材料有限公司
PLA-based degradable adhesive tape
InactiveCN114015369AGood thermal propertiesPromote degradationProtein adhesivesFilm/foil adhesivesPolymer scienceAdhesive
The invention discloses a PLA-based degradable adhesive tapewhich comprises a release layer, a base material layer and an adhesive layer; the base material layer is prepared from the following raw materials: PLA (polylactic acid), PBAT (butylene adipate-terephthalate) copolymer, starch, nano cellulose, a plasticizer, a cross-linking agent and a stabilizer; the release layer is prepared from a raw material containing silicone oil; and the adhesive layer is prepared from a degradable adhesive. The produced packaging material belongs to a degradable product, is green and environment-friendly and has good water resistance and flexibility, the step of removing an adhesive tape is omitted when a carton using the adhesive tape is recycled, and the recycling cost of the carton is reduced.
Owner:ZHEJIANG GREAT SHENGDA PACKING CO LTD
Preparation method of decellularized porcine dermal matrix dressing by using pork rind
InactiveCN109550075AReduce the risk of containing virusesLow antigenicityTissue regenerationProsthesisAntigenFreeze-drying
The invention discloses a preparation method of decellularized porcine dermal matrix dressing by using pork rind. The preparation method is characterized in that a physical method, a chemical method and a biochemistry method are adopted, a freeze drying technique is adopted, under the premise that a three-dimensional network structure of the pork rind is maintained unchanged, through the steps ofdegreasing, removing hair, alkali treatment for inactivation of virus, decellularizing, cross-linking, post-pretreatment, irradiation sterilization and the like, antigenic substances in the pork rindcan be effectively and thoroughly cleared, the shape of a hypodermal cell epimatrix is completely reserved, and the properties of the physical intensity, the hydrophilicity, the appropriate degradability, the storage stability and the like of the materials are improved.
Owner:JIANGYIN BENXIANG BIOTECHOLOGY
Self-assembled zinc-bismuth-antimony nanorod with self-supporting structure and a preparation method and application thereof
ActiveCN109603805AThe synthesis method is simpleThe preparation process is simple and controllableMaterial nanotechnologyWater/sewage treatment by irradiationHeterojunctionDyeing wastewater
The invention provides a self-assembled zinc-bismuth-antimony nanorod with a self-supporting structure and a preparation method and application thereof. Sodium bismuth, zinc acetate and antimony trichloride are used as raw materials, argon serves as carrier gas, high temperature calcination and conversion serve as main technical paths, and the antimony / zinc bismuth Schottky heterojunction nanorodis prepared by the one-step method. The composite can significantly improve the photocatalytic performance, and especially can improve the degradation rate of dye wastewater. The preparation method ofthe material is simple, low in cost and suitable for large-scale production, and can also be widely used in optical instruments, electronic devices, energy conversion and other fields.
Owner:SHANGHAI NAT ENG RES CENT FORNANOTECH
A kind of triptorelin sustained-release microparticles and preparation method thereof
ActiveCN105267153BQuality assuranceStable physical and chemical propertiesPeptide/protein ingredientsPharmaceutical non-active ingredientsMedicineTriptorelin
Owner:SHANGHAI SOHO YIMING PHARMA
Preparation method and application of ordered mesoporous carbon-activated carbon fibrofelt composite material
ActiveCN102730801BEasy to prepareLow costWater/sewage treatment by oxidationDyeing wastewaterCalcination
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
Naphthalene-degrading strain applied to sewage treatment and microbial agent and application thereof
InactiveCN110117555APromote degradationImprove domestication effectBacteriaWater contaminantsBiotechnologyMicrobial agent
The invention relates to the technical field of biodegradation in sewage treatment technologies, in particular to a naphthalene-degrading stain applied to sewage treatment. The naphthalene-degrading strain comprises bacillus subtilis, corynebacterium and rhodococcus. An incubator cultivation method comprises the steps that s1, degrading bacteria are screened, water samples are collected from petroleum-polluted seaports, and the bacillus subtilis, the corynebacterium and the rhodococcus are screened out; s2, strain domestication is conducted. The invention further discloses a microbial agent ofthe naphthalene-degrading strain applied to sewage treatment. The microbial agent comprises the bacillus subtilis, the corynebacterium and the rhodococcus, and the total viable bacteria number is 1.5*10<8>-6.0*10<8> cfu / mL. The invention further discloses application in inoculating the microbial agent of the naphthalene-degrading strain into a filler and applying the filler in a biodegrading pondfor degrading naphthalene in sewage. The biodegradable bacteria have the efficient and high degradation speed on naphthalene, the survival rate of the naphthalene-degrading strain in high concentration naphthalene-containing sewage is high, the treatment effect is good, the treatment speed is high, and secondary pollution does not exist.
Owner:博瑞德环境集团股份有限公司
Polyhydroxy fatty acid ester blood vessel stent and making method thereof
InactiveCN1258382CGood biocompatibilityPromote degradationSurgeryDilatorsPolytetramethylene terephthalateCell adhesion
The present invention relates to a polyhydroxy alkanoates blood vessel support and its preparation method. Said blood vessel support is made of porous internal membrane, solid external membrane and reinforcing rib. The reinforcing rib is winded around the surface layer of solid external membrane in the form of strip. The described porous internal membrane, solid external membrane and reinforcing rib are made up by using one of polyhydroxy butyrate, polyhydroxybutyric acid-pentanoate or polyhydroxybutyric acid-caproate or their blend and polyglycol-polybutylene glycol terephthalate copolymer blend. Said invention possesses good biological compatibility, anticoagulant property, cell adhesion and proper degrading speed, high mechanical strength and suture strength.
Owner:TSINGHUA UNIV
Novel composite hydrogel stent prepared by 3D biological printing technology and application of novel composite hydrogel stent
ActiveCN113181419AAccelerate the degradation rateImprove adhesionAdditive manufacturing apparatusBandagesCell-Extracellular MatrixCell adhesion
The invention discloses a novel composite hydrogel stent prepared by a 3D biological printing technology and application of the novel composite hydrogel stent. According to the invention, oxidized sodium alginate and sodium alginate are used as substrates, gelatin and calcium chloride are used as cross-linking agents, and calcium carbonate particles are used as a stabilizer. The composite stent is rough in surface, beneficial to cell adhesion, provided with a communicated hole structure uniform in size, capable of remarkably promoting the wound healing effect and good in degradation rate, and the degradation rate can be matched with the tissue regeneration rate. In the early stage of wound healing, the stent quickly absorbs tissue fluid, covers and fills the wound, and provides a microenvironment similar to an in-vivo extracellular matrix for cells; the porous supporting structure induces tissue cells to proliferate in parallel in the stent, collagen deposition is accelerated, and a complete nutrient supply platform is constructed. In the later stage of wound healing, since the scaffold contains oxidized sodium alginate, the degradation process of the oxidized sodium alginate promotes subsequent deposition of skin tissues in the scaffold and proliferation of tissue cells, the healing speed is increased, and scar formation is reduced.
Owner:SUN YAT SEN UNIV
Integral engineering rack of interface osteochondro tissue with bionic function
InactiveCN100522265CIncrease connection areaImprove connection strengthJoint implantsBiocompatibility TestingOrganic layer
The invention discloses an osteochondral composite tissue integrated engineering support with bionic function interface, which is composed of cartilage layer, calcification layer and subchondral bone layer from top to bottom, between the cartilage layer and calcification layer, calcification layer and subchondral bone The organic connection between the layers; the cartilage layer is composed of type II collagen and chitosan, and type II collagen / chitosan is connected in the form of covalent bonds; the composition of the calcified layer is type II collagen and hydroxyapatite, II Type I collagen / hydroxyapatite are connected by covalent bonds; the subchondral bone layer is composed of type I collagen and hydroxyapatite, and type I collagen / hydroxyapatite are connected by covalent bonds; the cartilage layer and More than one pore is provided in the subchondral bone layer, and the pore diameter of the pore is 100 μm to 500 μm. The stent of the present invention has good biocompatibility, controllable degradability and sufficient mechanical strength, and has a bionic functional interface; after being transplanted into the patient's body, it can withstand the stress of the normal state and meet the mechanical requirements of the implanted site; The rate of degradation and absorption matches the growth rate of new tissue in the host.
Owner:THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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