The invention relates to a high-performance tire tread rubber and a preparation method thereof, wherein the high-performance tire tread rubber comprises, by mass, 60-90 parts of natural rubber, 0-20 parts of cis-1,4-polybutadiene rubber, 9-20 parts of a low molecular weight trans butadiene-isoprene copolymerization rubber, 40-60 parts of carbon black, 0-20 parts of white carbon black, 0-2 parts ofa silane coupling agent, 1-5 parts of zinc oxide, 1-5 parts of stearic acid, 0.3-3 parts of sulfur, 0.5-5 parts of an accelerator, 1-3 parts of an anti-aging agent, and 1-10 parts of other auxiliaryagents. According to the present invention, the tire tread rubber is modified with the low molecular weight trans butadiene-isoprene copolymerization rubber, such that the tensile strength of the vulcanized rubber is increased by 15-20%, the tear strength is increased by 1%-20%, the 60 DEG C loss factor is reduced by 4-20%, and the wear is reduced by 10-25%; and various performances of the tire tread rubber material of the present invention meet the performances of the tire tread rubber.