Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Skin care cosmetic containing liposome recombinant human growth hormone and preparation method thereof

A technology for human growth hormone and skin care, which is applied in skin care preparations, cosmetic preparations, cosmetics and other directions, can solve the problems of the decline of the activity of recombinant human growth hormone, and achieve the effect of improving the encapsulation rate and maintaining the activity for a long time.

Inactive Publication Date: 2010-05-26
江西宇骏生物工程有限公司
View PDF1 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The recombinant human growth hormone in the technical solution recorded in the 03129040.X patent is not protected by liposomes. When the recombinant human growth hormone is used in cosmetics, the activity of the recombinant human growth hormone gradually decreases over time

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, a kind of cosmetics containing liposome recombinant human growth hormone for skin care, wherein: mixed by the following raw materials in weight ratio: 1.80 parts of polyoxyethylene fatty alcohol ether, 0.75 parts of polysorbate fat 60, 7.30 parts Glyceryl monolaurate, 1.75 parts cetyl alcohol, 4.00 parts liquid paraffin, 6.95 parts glycerin, 0.20 parts sodium polyacrylate, 0.20 parts polyvinylpyrrolidone K30, 1.95 parts alpha-lipoic acid, 0.80 parts fragrance, 0.80 parts preservative, 71.40 parts of ionized water, 0.15 parts of liposomal human growth hormone.

Embodiment 2

[0021] Embodiment 2, a preparation method of cosmetics containing liposome recombinant human growth hormone for skin care, wherein: mixed with the raw materials in the following weight ratio: 1.80 parts of polyoxyethylene fatty alcohol ether, 0.75 part of polysorbate 60 , 7.30 parts of glyceryl monolaurate, 1.75 parts of cetyl alcohol, 4.00 parts of liquid paraffin, 6.95 parts of glycerin, 0.20 parts of sodium polyacrylate, 0.20 parts of polyvinylpyrrolidone K30, 1.95 parts of α-lipoic acid, 0.80 parts of fragrance, 0.80 parts Preservatives, 71.40 parts of ionized water, 0.15 parts of liposomal human growth hormone;

[0022] The preparation method of liposomal human growth hormone is as follows:

[0023] The weight ratio of the main raw materials is: 1 part of lecithin, 7 parts of absolute ethanol, 2 parts of trehalose, and 1 part of recombinant human growth hormone;

[0024] After dissolving 1 part of lecithin with 6 parts of absolute ethanol, add phosphate buffer to adjust ...

Embodiment 3

[0025] Embodiment 3, a kind of preparation method of cosmetics containing liposome recombinant human growth hormone for skin care, wherein: mixed by the raw materials of following weight ratio: 7.30 parts of glyceryl monolaurate, 1.75 parts of cetyl alcohol, 4.00 parts Liquid paraffin, 7.00 parts of glycerin, 0.20 parts of sodium polyacrylate, 0.20 parts of polyvinylpyrrolidone K30, 1.95 parts of α-lipoic acid, 0.80 parts of spices, 0.80 parts of preservatives, 71.40 parts of ionized water, 0.15 parts of liposomal human growth hormone;

[0026] The preparation method of liposomal human growth hormone is as follows:

[0027] The weight ratio of the main raw materials is: 1 part of lecithin, 7 parts of absolute ethanol, 2 parts of trehalose, 1 part of recombinant human growth hormone, 1.8 parts of polyoxyethylene fatty alcohol ether, 0.7 part of polysorbate 60;

[0028] After dissolving 1.8 parts of polyoxyethylene fatty alcohol ether, 0.7 part of polysorbate 60 and 1 part of le...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a skin care cosmetic, in particular to a skin care cosmetic containing liposome recombinant human growth hormone. The cosmetic comprises polyoxyethylene fatty alcohol ether, polysorbate 60, monolaurin, hexadecanol, liquid paraffin, glycerol, sodium polyacrylate, polyvinylpyrrolidone K30, alpha-lipoic acid, perfume, preservative, ionized water, liposome human growth hormone. A surface active agent is introduced in the preparation process of liposome so that the encapsulation rate of the liposome human growth hormone is obviously improved. The invention can emulsify a product by a production technology of micro-emulsion to prepare millimicro-emulsion with the grain diameter of 100-200mm, thereby improving the local penetrability of the cosmetic on the skin, enabling an active substance to directly act on the horny layer to be uniformly distributed and showing more favorable effects of aging resistance, facial care, and the like and being more suitable for sensitive skin.

Description

technical field [0001] The invention relates to skin care cosmetics, in particular to skin care cosmetics containing liposome recombinant human growth hormone (rhGH) and a preparation method thereof. Background technique [0002] Recombinant human growth hormone is a drug approved by the national drug administration department, and it is recorded in the Chinese Pharmacopoeia on page 494 of the second part of the 2000 edition. [0003] Recombinant human growth hormone is a protein composed of 191 amino acid residues or 192 amino acid residues with -methionine at the N-terminal. It belongs to biologically active peptide analogues. Influenced by enzymes and other factors, it is directly used in cosmetics. Although it has a certain skin care effect, it is difficult to obtain better results. [0004] Experiments have proved that: Cosmetics containing recombinant human growth hormone: can promote skin epidermal hyperplasia and keratinization, enhance cell activity, accelerate the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K8/92A61K8/64A61Q19/00
Inventor 周隆才吴云江楼根福楼秀余梁华正
Owner 江西宇骏生物工程有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com