5 results about "Gut immunity" patented technology

This invention relates to a strain of *Lactobacillus plantarum* with accession number 35817 from the China General Microbiological Culture Collection Center (CGMCC), and its application in improving intestinal immune function and promoting human intestinal health. This strain can be used as a probiotic ingredient to prepare compositions with the following functions: enhancing resistance to intestinal bacterial infections, maintaining intestinal barrier function, and regulating inflammatory responses. The compositions can be formulated into foods, beverages, or pharmaceuticals for enhancing intestinal immune function and intestinal health.

The present invention relates to the field of probiotics, in particular to an Akkermansia muciniphila MG784 for alleviating constipation, promoting defecation, improving intestinal barrier function and intestinal immunity, and its uses. The Akkermansia muciniphila MG784 provided by the present invention has the deposition number DSM 35549. The Akkermansia muciniphila MG784 provided by the present invention can increase the levels of motilin (MTL), gastrin (GAS), and acetylcholine in the gastrointestinal tract, promote intestinal peristalsis, improve the small intestine propulsion rate, and ameliorate defecation time and fecal output. Furthermore, Akkermansia muciniphila MG784 can also alleviate colonic mucosal inflammation, improve the thickness of the digestive tract muscular layer, modulate the structure of the intestinal microbiota, significantly increase the abundance of beneficial bacteria, and decrease the abundance of harmful bacteria.

Bacillus strain compositions and methods for converting (i) one or more polysaccharides into short chain polysaccharides and / or monosaccharides and / or (ii) one or more proteins into short chain polypeptides and / or amino acids are provided. The Bacillus strain composition can comprise Bacillus subtilis 750 or an active variant thereof, and optionally at least one of Bacillus subtilis 747, Bacillus subtilis 839, Bacillus subtilis 1781, Bacillus subtilis 1999, Bacillus subtilis 2018, or an active variant thereof. Compositions provided herein can be fed to animals in an effective amount to increase digestibility of one or more polysaccharides and / or one or more proteins; increase nutrition efficiency and / or energy partitioning; increase nutrient absorption; enhance gut immunity and / or gut barrier integrity; and / or inhibit a pathogen in the gastrointestinal tract of the animal.

The invention relates to the field of biological medicine, and discloses a composition targeting a lactobacillus johnsonii-tryptophan metabolic axis and application of the composition. The composition comprises a traditional Chinese medicine extract and lactobacillus johnsonii, the traditional Chinese medicine extract is prepared from radix bupleuri, radix paeoniae alba, fructus aurantii immaturus and honey-fried licorice root. Traditional Chinese medicine extracts of radix bupleuri, radix paeoniae alba, fructus aurantii immaturus and honey-fried licorice root are compounded with lactobacillus johnsonii according to a specific proportion, tryptophan is promoted to be converted into 5-hydroxytryptamine, kynurenine is inhibited from being generated, depression-like behaviors are effectively relieved, the traditional Chinese medicine composition can cooperate with anticancer drugs to remarkably inhibit cancer cell growth, meanwhile, the intestinal barrier function can be improved, the intestinal immunity can be improved, and the curative effect is good. The invention provides a high-safety synergistic treatment scheme with triple effects of tumor inhibition, depression resistance and intestinal tract improvement for patients with liver cancer and depression.

A Bifidobacterium longum subsp. infantis YLGB-1496 bacterial preparation, a preparation method, and a use thereof. The bacterial preparation is prepared by fermentation of a viable bacterium of Bifidobacterium longum subsp. infantis, and is prepared from the viable bacterium of Bifidobacterium longum subsp. infantis and its metabolite of specific composition; and the bacterial preparation is used for intestinal health regulation, has efficacies such as an anti-inflammatory efficacy, enhanced gut immunity, regulation of gut microbiota, and alleviation of intestinal bloating, can be used for the preparation of fermented foods, drugs, or animal feed, and has wide application prospects.