Polypeptide composition capable of effectively improving acne and repairing skin damage

A polypeptide composition and composition technology, applied in the direction of medical preparations containing active ingredients, drug combinations, skin care preparations, etc., can solve problems such as delayed treatment timing, damaged skin tissue, and complicated acne course, and promote Effects of regeneration and strengthening, relief of inflammation and symptoms, and promotion of keratinocyte differentiation

Pending Publication Date: 2019-01-04
SHENZHEN WINKEY MEDICAL RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of these products claim to be anti-inflammatory and anti-acne in a short period of time. In fact, most of them contain banned ingredients such as hormones and chemical antibacterial agents. Long-term use of these cosmetics is tantamount to drinking poison to quench thirst, causing skin allergies and causing Propionibacterium acnes , Staphylococcus aureus, etc. develop drug resistance, delay the best treatment opportunity, make the course of acne more complicated, and eventually lead to severe damage to skin tissue, permanent scars on the face, and irreparable harm to patients

Method used

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  • Polypeptide composition capable of effectively improving acne and repairing skin damage
  • Polypeptide composition capable of effectively improving acne and repairing skin damage
  • Polypeptide composition capable of effectively improving acne and repairing skin damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Acne Gel Recipe

[0033]

[0034]

[0035] Preparation method:

[0036] Under the condition of rapid stirring, slowly add the formula amount of Carbomer 940 into some deionized water, fully disperse evenly, and heat to dissolve completely.

[0037] Heat the remaining deionized water to about 35°C, dissolve palmitoyl tripeptide-8 in warm water, continue to add myristoyl hexapeptide-5, glycerin, butanediol, β-glucan, and phenoxyethanol, and stir to make it completely dissolve.

[0038] Mix the above two, stir evenly, add triethanolamine to neutralize, and degas until the product has no bubbles.

Embodiment 2

[0040] Acne Gel Recipe

[0041]

[0042] Preparation method:

[0043] Under the condition of rapid stirring, slowly add the formula amount of Carbomer 940 into some deionized water, fully disperse evenly, and heat to dissolve completely.

[0044] To the remaining deionized water, add myristoyl hexapeptide-5, hexapeptide-9, glycerin, butylene glycol, β-glucan, and phenoxyethanol, and stir to dissolve completely.

[0045] Mix the above two, stir evenly, add triethanolamine to neutralize, and degas until the product has no bubbles.

Embodiment 3

[0047] acne gel prescription

[0048]

[0049] Preparation method:

[0050] Under the condition of rapid stirring, slowly add the formula amount of Carbomer 940 into some deionized water, fully disperse evenly, and heat to dissolve completely.

[0051] Heat the remaining deionized water to about 35°C, dissolve palmitoyl tripeptide-8 in warm water, and continue to add myristoyl hexapeptide-5, hexapeptide-9, glycerin, butylene glycol, β-glucan, and phenoxyethanol , stir to dissolve completely.

[0052] Mix the above two, stir evenly, add triethanolamine to neutralize, and degas until the product has no bubbles.

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PUM

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Abstract

The invention discloses a polypeptide composition capable of effectively improving acne and repairing skin damage. The polypeptide composition comprises antibacterial polypeptides, polypeptides capable of inhibiting inflammatory response and / or polypeptides capable of promoting collagen and keratin regeneration and repairing acne marks. The polypeptide composition has the advantages that the growth and propagation of propionibacterium acnes and staphylococcus aureus can be inhibited, inflammatory response can be inhibited, edema and couperose skin can be prevented, corium layer collagen synthesis is increased, the regeneration and reinforcing of dermal-epidermis junction (DEJ) area structure tissue can be promoted, epidermis cell differentiation and maturation can be promoted, acne marks can be effectively repaired, and effective acne improving and skin damage repairing can be achieved.

Description

technical field [0001] The invention belongs to the technical field of biomedical polypeptide drugs and provides a polypeptide composition for effectively improving acne and repairing skin lesions. Background technique [0002] Acne (acne) is a common chronic inflammatory skin disease that occurs in the pilosebaceous gland. scar. Often said comedo also belongs to acne. [0003] Acne can be caused by various factors inside and outside the body, and its pathogenesis is closely related to factors such as excessive sebum secretion, pilosebaceous gland duct blockage, bacterial infection and inflammatory response. Excessive stress, disordered daily routines, and endocrine disorders will all lead to increased sebum secretion, especially the strong secretion of androgen during puberty, which will promote the secretion of a large amount of oil from the sebaceous glands, and at the same time affect the abnormal keratinization of the pilosebaceous gland ducts, and then block the pilo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/08A61K38/07A61K8/64A61Q19/00A61Q17/00A61P17/00A61P17/10A61K38/06
CPCA61K8/64A61K38/06A61K38/07A61K38/08A61K2800/5922A61Q17/005A61Q19/00A61P17/00A61P17/10A61K2300/00
Inventor 丁文锋
Owner SHENZHEN WINKEY MEDICAL RES DEV
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