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Patch for treating pediatrics febricide

A patch and pediatric technology, applied in the field of antipyretic patches for children, can solve problems such as toxic and side effects, achieve the effect of less irritation, no toxic and side effects, and improve bioavailability

Inactive Publication Date: 2008-06-18
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Generally, after children have a fever, they are usually treated with medicines, mostly oral medicines or injections, but both oral medicines and injections have toxic side effects, and they will produce a reaction through the first-pass effect of the liver and the release of the digestive tract, which brings safety to the patient. question

Method used

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  • Patch for treating pediatrics febricide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1 (high dose)

[0033] The weight ratio is based on 1kg per serving:

[0034] Aspirin 60kg, phenobarbital 30kg, natural borneol 10kg, peppermint oil 6kg.

Embodiment 2

[0035] Embodiment 2 (high dosage)

[0036] The weight ratio is based on 1kg per serving:

[0037] Paracetamol 50kg, phenobarbital 30kg, natural borneol 10kg, peppermint oil 6kg.

Embodiment 3

[0038] Embodiment 3 (low dosage)

[0039] The weight ratio is based on 1kg per serving:

[0040] Aspirin 30kg, phenobarbital 15kg, natural borneol 3kg, peppermint oil 3kg.

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PUM

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Abstract

The invention relates to a patch for abating fever of children, which is composed of the following components according to the weight proportion: 5 to 10 portions of wrinkled glanthyssop leaves, 3 to 10 portions of origanum vulgare leaves and 3 to 10 portions of mentha leaves. According to the proportion, the raw materials are well mixed and ground, and the particle size of each component is 100 to 200 microns; the raw materials are supercritical fluid extracted by CO2; the needed fraction is fractionated to be obtained by the fractionator; after through nanometer dispersion equipment, the components in the formula are prepared into nanometer propellant slurry; due transdermal enhancer and pressure sensitive adhesive are added into the nanometer propellant slurry; the nanometer propellant slurry is sent into the hover type low temperature drying coater; and after coated, the nanometer propellant slurry is sheared, inspected by quality and packaged to be stored in the warehouse. The invention processes and extracts the medicinal materials with scientific method; filled and loaded inside the skeleton of matrix, the patch matrix has good solubility with skin, which is favorable for the drug molecules to pass through; the drug is released slowly; the administration is stable; the stimulation is slight without side effect; and the invention solves the problem that the oral drugs and injections bring side effect, and avoids the side effect caused by oral administration.

Description

technical field [0001] The invention relates to a traditional Chinese medicine patch, in particular to an antipyretic patch for treating children. Background technique [0002] Generally, after children have a fever, they are usually treated with medicines, mostly oral medicines or injections, but both oral medicines and injections have toxic side effects, and they will produce a reaction through the first-pass effect of the liver and the release of the digestive tract, which brings safety to the patient. question. Contents of the invention [0003] The main purpose of the present invention is to solve the toxic and side effects of oral medicines and injections on the human body, and provide a antipyretic patch for treating children that avoids the toxic and side effects of oral administration and does not undergo the first-pass effect of the liver and the dilution of the digestive tract. . [0004] The technical solution adopted by the present invention to solve its tec...

Claims

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Application Information

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IPC IPC(8): A61K31/616A61K31/515A61K9/70A61K47/42A61P29/00A61K31/045A61K31/167A61K47/32
Inventor 李建民高惠明
Owner TIANJIN ZHONGBAO PHARMACY
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