30 results about "Nicotine replacements" patented technology

Nicotine in base or salt form combined with cosmetic ingredients to form a lip balm or similar stick. The stick is readily dispensed not only onto a person's lips but also may be used on the skin, for example on the wrist. Packaging the nicotine this way enables a smoker to obtain nicotine discretely anywhere in public, without offending others by smoking. Furthermore, the dosage is readily controlled, and the person's hands and mouth are active, similar to the lighting and smoking of a cigarette.

Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient.

The present invention relates to iontophoretic transdermal delivery of nicotine salts useful for nicotine replacement therapy for an individual in need thereof. The present invention further relates to the iontophoretic transdermal delivery of nicotine maleate and nicotine citrate. Methods of reducing skin irritation generally caused by transdermal nicotine delivery by iontophoretic transdermal delivery of nicotine salts are also disclosed.

A method for predicting nicotine replacement dosage to achieve a target nicotine serum concentration relies on measuring blood nicotine concentration prior to smoking cessation. At least two values corresponding to other patient characteristics, such as body mass, cumulative smoking, psychological dependence, age, and menopausal status, are also determined and used to predict expected blood nicotine concentrations based on nicotine replacement dosages. Such methods are useful in achieving target blood nicotine concentrations for smoking cessation and therapy.

The invention relates to a pharmacologically active combination, having utility in treating insomnia patients, which comprises: (a) at least one first active ingredient selected from melatonin, other melatonergic agents, melatonin agonists and melatonin antagonists; and (b) at least one second active ingredient selected from nicotine and nicotine receptor agonists; to use of a medicament containing component (a) with or without component (b) for alleviation of at least one adverse effect which occurs in a patient in the course of nicotine replacement therapy, or otherwise, selected from impairment of the quality of sleep, impairment of cognition and impairment of memory, as well as to a kit having utility in treating insomnia patients, which comprises components (a) and (b) in unit dosage form.

The present invention relates to a nicotine-containing pharmaceutical composition and methods of using the composition in therapies, such as nicotine replacement therapy.

The invention relates to the technical field of nicotine replacement therapy products, and discloses a nicotine granule composition, which mainly comprises nicotine quick-release granules and nicotinesustained-release granules, and the nicotine quick-release granules mainly comprise a nicotine raw material, a filler, an adhesive, a buffer agent, a sweetener and an edible essence; the nicotine sustained-release granules mainly comprise the following components: a nicotine raw material, a polymer sustained-release material, an adhesive, a buffer agent, a sweetener and an edible essence. The invention also discloses a method for preparing the nicotine granule mixture and a preparation device thereof. The nicotine granule composition provided by the invention can guarantee the speed of obtaining pleasant sensation of a human body and the duration of nicotine maintaining the concentration with a treatment effect in a human body through the nicotine quick-release granules and the nicotine sustained-release granules, so that smoking addicts can get rid of the dependence on smoking better, and has a better treatment effect than the similar products sold on the market.

The present invention is drawn to nicotine-containing pharmaceutical compositions that comprise chocolate and method of using the compositions in different therapies, such as nicotine replacement therapy.

A composition intended to be employed for therapeutic purposes incorporates a source of nicotine and at least one levulinate moiety. Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) or nicotine polacrilex. The levulinate moiety can have the form of an acid (e.g., levulinic acid), a levulinate salt (e.g., sodium levulinate), or an ester of levulinic acid (e.g., methyl levulinate or ethyl levulinate). The composition can incorporate nicotine and levulinic acid in a salt form (e.g., nicotine levulinate). The composition can be composed of at least two forms of nicotine, and one of the forms of nicotine is in the form of nicotine levulinate. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and as a nicotine replacement therapy.

The invention relates to the technical field of nicotine replacement therapy products, and discloses a nicotine granule composition, which mainly comprises nicotine quick-release granules and nicotinesustained-release granules, and the nicotine quick-release granules mainly comprise a nicotine raw material, a filler, an adhesive, a buffer agent, a sweetener and an edible essence; the nicotine sustained-release granules mainly comprise the following components: a nicotine raw material, a polymer sustained-release material, an adhesive, a buffer agent, a sweetener and an edible essence. The invention also discloses a method for preparing the nicotine granule mixture and a preparation device thereof. The nicotine granule composition provided by the invention can guarantee the speed of obtaining pleasant sensation of a human body and the duration of nicotine maintaining the concentration with a treatment effect in a human body through the nicotine quick-release granules and the nicotine sustained-release granules, so that smoking addicts can get rid of the dependence on smoking better, and has a better treatment effect than the similar products sold on the market.

A composition suitable for use in nicotine replacement therapy products includes a nicotine product that includes a synthetic nicotine that is substantially free of one or more contaminants and/or impurities normally associated with tobacco-derived nicotine. For example, the synthetic nicotine is substantially free of one or more of nicotine-1'-N-oxide, nicotyrine, nornicotyrine, 2',3-bipyridyl, cotinine, anabasine, and/or anatabine. The composition further comprises one or more pharmaceutically acceptable excipients, additives and/or carriers. The nicotine replacement therapy products may include any number of such products, including transdermal nicotine delivery patches, nicotine gums, synthetic chewing tobacco, synthetic snuff, and synthetic strips (e.g., dissolvable synthetic tobacco). Additionally, a method of treating nicotine addiction includes administering a nicotine replacement composition, e.g., via a nicotine replacement therapy product, to a user.

A composition intended to be employed for therapeutic purposes incorporates nicotine and at least one other nicotinic compound. Representative forms of nicotine can be as a free base (e.g., as a mixture of nicotine and microcrystalline cellulose), as a form of nicotine salt (e.g., as nicotine bitartrate) or as nicotine polacrilex. The other nicotinic compound is a compound that can be considered to bind selectively to certain nicotinic receptor subtypes, and particularly those of the central nervous system. For example, the other nicotinic compound can be a compound that binds selectively to the nicotinic receptor subtypes a7 or a4ss2. The composition is useful for treatment of central nervous system conditions, diseases and disorders, and as a nicotine replacement therapy.

The present invention relates to nicotine-containing chewing gum compositions and the method of preparing the same. The present invention provides improved and stable nicotine-containing chewing gum compositions for use in nicotine replacement therapy, which provide rapid nicotine release in the oral cavity and effectively satisfy the craving that most smokers experience.

A method of reducing nicotine cravings is described. The method includes inhalation of a dry powder formulation containing a dose of nicotine by a subject seeking nicotine cravings reduction. The formulation includes amounts and concentrations of nicotine that are significantly lower than cigarettes or nicotine replacement therapies.

A smoking cessation device for use in nicotine replacement therapy includes an imitation smoking implement with a body sized and shaped substantially identical to a conventional smoking implement chosen from the group consisting of a cigarette, a cigarillo, a cigar, and a pipe. The device also includes one or more nicotine replacement modules removably disposed at one end of the body, the one or more nicotine replacement modules removable from the imitation smoking implement by a user to ingest said nicotine replacement modules as part of a nicotine replacement therapy. Optionally, a plurality of said imitation smoking implements can be held in a package sized and shaped to resemble a conventional box of cigarettes, cigarillos or cigars. Said imitation smoking implement can be held by the user in their hands or lips while consuming the one or more nicotine replacement modules to simulate a conventional smoking ritual.

A smoking cessation device for use in nicotine replacement therapy includes an imitation smoking implement with a body sized and shaped substantially identical to a conventional smoking implement chosen from the group consisting of a cigarette, a cigarillo, a cigar, and a pipe. The device also includes one or more nicotine replacement modules removably disposed at one end of the body, the one or more nicotine replacement modules removable from the imitation smoking implement by a user to ingest said nicotine replacement modules as part of a nicotine replacement therapy. Optionally, a plurality of said imitation smoking implements can be held in a package sized and shaped to resemble a conventional box of cigarettes, cigarillos or cigars. Said imitation smoking implement can be held by the user in their hands or lips while consuming the one or more nicotine replacement modules to simulate a conventional smoking ritual.

The present invention is drawn to nicotine-containing pharmaceutical compositions that comprise chocolate and method of using the compositions in different therapies, such as nicotine replacement therapy.

The invention provides masticatory pattern cigarette alternative food. The raw materials of the alternative food include barbary wolfberry fruit, peach gum, herba rhodiolae, honey-fried licorice root, rose, peppermint, dried tangerine peel and tobacco leaves. The alternative food can be used as nicotine replacement therapy to relieve the onset of a craving for tobacco and can avoid all the associative negative effects brought by smoking.