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A kind of nicotine particle composition and its preparation method and its preparation device

A technology of nicotine and granules, which is used in drug combinations, devices that make drugs into special physical or taking forms, and pharmaceutical formulations, can solve the problems of unreasonable nicotine release speed and unsatisfactory treatment effect, and achieve prolonged pleasure. time, suppressing the desire to smoke, and helping to quit smoking

Active Publication Date: 2022-05-27
重庆市义力医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The object of the present invention is to provide a mixture of nicotine granules to solve the problem of unsatisfactory therapeutic effect due to the unreasonable nicotine release rate provided by the products used in the existing nicotine replacement therapy proposed in the background art

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  • A kind of nicotine particle composition and its preparation method and its preparation device
  • A kind of nicotine particle composition and its preparation method and its preparation device
  • A kind of nicotine particle composition and its preparation method and its preparation device

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Embodiment Construction

[0044] The technical solutions in the embodiments of the present invention will be described clearly and completely below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the technical solutions in the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of the present invention.

[0045] The invention provides a technical solution: a nicotine granule mixture is mainly prepared by mixing nicotine immediate-release granules and nicotine sustained-release granules in a ratio of 2:1 by weight;

[0046] Wherein the nicotine immediate-release granules are composed of the following components by weight percentage: nicotine distartrate dihydrate 3.53%, microcrystalline cellulose 25.26%, mannitol 54.9%, povidone 5.1%, sodium carbonate 4.0%, sodium bicarbonate 6.4%, acesulfame potassium 0.2%, menthol 0.2% a...

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Abstract

The invention relates to the technical field of products for nicotine replacement therapy, and discloses a nicotine granule composition, which is mainly composed of nicotine immediate-release granules and nicotine sustained-release granules, wherein the components of the nicotine immediate-release granules mainly include: nicotine raw materials, fillers , binders, buffers, sweeteners and food flavors; the components of nicotine sustained-release granules mainly include: nicotine raw materials, polymer slow-release materials, binders, buffers, sweeteners and food flavors. The invention also discloses a method and a preparation device for preparing the nicotine particle mixture. The nicotine granule composition provided by the present invention can ensure the speed at which the human body obtains pleasure and the duration of nicotine in the human body to maintain a therapeutically effective concentration through the nicotine immediate-release granule and the nicotine sustained-release granule, thereby facilitating smokers to better get rid of the habit of smoking The dependence of the drug has better therapeutic effect compared with similar products sold in the existing market.

Description

technical field [0001] The invention relates to the technical field of nicotine replacement therapy products, in particular to a nicotine particle composition, a preparation method and a preparation device thereof. Background technique [0002] Tobacco products currently on the market are mainly made of tobacco containing nicotine. After the human body smokes tobacco products, nicotine will enter the brain through the blood in about ten seconds, thereby providing a sense of satisfaction. This sense of satisfaction will stay in the human body for a period of time, causing nicotine to become a strong addictive substance and the human body will also become dependent on nicotine, making it difficult for smokers to quit smoking. Nicotine itself is less harmful to the human body, but tobacco products will produce a large amount of carcinogens during smoking, such as ammonium nitrite, carbon monoxide and tar products, which lead to smoking behavior and seriously endanger the healt...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K47/38A61K47/26A61K47/32A61K47/02A61K47/10A61K31/465A61P25/34A61J3/00A24B15/16
CPCA61K9/1652A61K9/1635A61K9/1623A61K9/1611A61K9/1617A61K31/465A61P25/34A61J3/00A24B15/16
Inventor 朱波
Owner 重庆市义力医药科技有限公司
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