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Nicotine granule composition and preparation method thereof

A technology of nicotine and granules, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations of non-active ingredients, etc., can solve the problems of unreasonable nicotine release rate and unsatisfactory treatment effect, so as to prolong the time of providing pleasure and suppress desire. The desire to smoke, the effect of helping smoking cessation

Active Publication Date: 2021-01-15
重庆市义力医药科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a mixture of nicotine granules to solve the problem of unsatisfactory therapeutic effect due to the unreasonable nicotine release rate provided by the products used in the existing nicotine replacement therapy proposed in the background art

Method used

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  • Nicotine granule composition and preparation method thereof
  • Nicotine granule composition and preparation method thereof
  • Nicotine granule composition and preparation method thereof

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Embodiment Construction

[0034] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the technical solutions in the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0035] The invention provides a technical solution: a mixture of nicotine granules, which is mainly made by mixing nicotine quick-release granules and nicotine sustained-release granules in a ratio of 2:1 by weight;

[0036] The nicotine immediate-release granules are composed of the following components according to weight percentage: 3.53% nicotine bitartrate dihydrate, 25.26% microcrystalline cellulose, 54.9% mannitol, 5.1% povidone, 4.0% sodium carbonate, sodium bicarbonate 6.4%, acesulfame potassium 0.2%, menthol 0.2% a...

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Abstract

The invention relates to the technical field of nicotine replacement therapy products, and discloses a nicotine granule composition, which mainly comprises nicotine quick-release granules and nicotinesustained-release granules, and the nicotine quick-release granules mainly comprise a nicotine raw material, a filler, an adhesive, a buffer agent, a sweetener and an edible essence; the nicotine sustained-release granules mainly comprise the following components: a nicotine raw material, a polymer sustained-release material, an adhesive, a buffer agent, a sweetener and an edible essence. The invention also discloses a method for preparing the nicotine granule mixture and a preparation device thereof. The nicotine granule composition provided by the invention can guarantee the speed of obtaining pleasant sensation of a human body and the duration of nicotine maintaining the concentration with a treatment effect in a human body through the nicotine quick-release granules and the nicotine sustained-release granules, so that smoking addicts can get rid of the dependence on smoking better, and has a better treatment effect than the similar products sold on the market.

Description

technical field [0001] The invention relates to the technical field of products for nicotine replacement therapy, in particular to a nicotine particle composition and a preparation method thereof. Background technique [0002] Tobacco products currently on the market are mainly made of tobacco containing nicotine. After the human body smokes tobacco products, nicotine will enter the brain through the blood in about ten seconds, thereby providing a sense of satisfaction. This sense of satisfaction will stay in the human body for a period of time, causing nicotine to become a highly addictive substance so that the human body will also become dependent on nicotine, making it difficult for smokers to quit smoking. Nicotine itself is less harmful to the human body, but tobacco products will produce a large amount of carcinogens during smoking, such as nitrosamine, carbon monoxide and tar products, which lead to smoking behavior that seriously endangers the health of smokers. ...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K47/38A61K31/465A61P25/34
CPCA61K9/1652A61K31/465A61P25/34Y02A50/30
Inventor 朱波
Owner 重庆市义力医药科技有限公司
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