Bactericidal composition containing berberine and tebuconazole

A technology of tebuconazole and berberine, which is applied in the field of pesticides, can solve the problems of environmental pollution, rapid development of germ resistance, and large dosage of pesticides, and achieve the effects of reducing costs, reducing dosage, and reducing pollution

Active Publication Date: 2015-12-02
BONTECH WELFARE ACADEMY OF ENVIRONMENTAL SCI BEIJING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The purpose of the present invention is to provide a highly efficient and safe bactericidal composition containing berberine and tebuconazole in order to overcome the shortcomings of the above-mentioned single bactericide, such as large dosage of medicament, serious environmental pollution, and fast generation of germ resistance.

Method used

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  • Bactericidal composition containing berberine and tebuconazole
  • Bactericidal composition containing berberine and tebuconazole
  • Bactericidal composition containing berberine and tebuconazole

Examples

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Effect test

example 1

[0029] Bioassay Example 1 : Indoor Toxicity Determination of Berberine and Tebuconazole Complex against Rice Bacterial Leaf Spot

[0030] Test object: Bacterial leaf spot of rice collected from the field

[0031] Test method: make the mother liquor with a certain concentration of the test agent, and then dilute it with water according to the set ratio to prepare 5-6 concentrations. Set clean water as the control, and add the concentration of bacteria containing 1×10 7 In the cfu / mL NB culture medium, in a constant temperature shaker at 28°C and 130r / m, after culturing for 24 hours, use a UV spectrophotometer to measure the absorbance value at a wavelength of 600nm, and calculate the antibacterial rate according to formula 2-3. The drug concentration was converted into logarithm, and the bacteriostatic rate was converted into a probability value for linear regression, and the toxicity regression equation and EC50 value (HalfMaximalEffectiveConcentration, EC50) were calculated....

Embodiment 1

[0047] Example 1 : 1% Berberine. Tebuconazole Granules

[0048]

[0049] Add xylene to berberine and tebuconazole, and then stir them fully to dissolve them completely; under stirring, slowly add propylene glycol to the system, stir fully for 30 minutes, dissolve them completely, and form a stable solution.

[0050] First add 12-60 mesh zeolite into the mixer, then add the above stable solution into it, mix for 30 minutes, after screening and testing, you can get 1% berberine. Tebuconazole granules.

Embodiment 2

[0051] Example 2 : 10% Berberine. Tebuconazole microcapsule suspension

[0052]

[0053] Dissolve 2% prothiostrobin and 8% tebuconazole in 5% xylene, then pump in 0.3% tributyl phosphate, 2.4% carboxymethyl cellulose, and 2.7% sodium alginate under high shear High-speed shear in the kettle for 30 minutes, add 20% urea-formaldehyde resin prepolymer, heat up and solidify for 60 minutes under stirring at 2000 rpm, then add deionized water, 4.5% sodium dinaphthyl methane disulfonate, 1.8% bentonite, and stir 10% berberine·tebuconazole microcapsule suspension can be obtained evenly.

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Abstract

The invention discloses a bactericidal composition containing berberine and tebuconazole. The bactericidal composition is prepared by compounding the active ingredients including berberine and tebuconazole in a mass ratio of (1 to 9)-(9 to 1). The bactericidal composition can be prepared into conventional dosage forms in the pesticide science, such as wettable powder, water dispersible granules, suspensions, microcapsule suspensions, granules or emulsion in water. The bactericidal composition has the advantages of high efficiency, little environmental pollution, capability of delaying the resistance of germs to drugs, and the like, and can be used for controlling diseases of various crops, especially rice bacterial leaf streak.

Description

technical field [0001] The invention belongs to the technical field of pesticides, and relates to a pesticide composition, in particular to a bactericidal composition containing berberine and tebuconazole. Background technique [0002] During the entire growth process of crops, they are faced with the threat of many pests such as diseases, insects, and weeds. Among them, diseases, especially fungal diseases, are characterized by various types, complex symptoms, rapid spread, serious damage, and compound occurrence. It makes it more difficult to control and poses a huge threat to crop yield and quality. In the process of agricultural production, in order to reduce the losses caused by fungal diseases, chemical control is one of the more significant means at present. The currently used medicaments produce different degrees of resistance, and it is reported that due to this unscientific drug use method, the resistance generation time of various medicaments is shortened year by...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N43/90A01P1/00A01P3/00A01N43/653
Inventor 张宗斌
Owner BONTECH WELFARE ACADEMY OF ENVIRONMENTAL SCI BEIJING CO LTD
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