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Chinese medicine composition for clearing away and toxic material, drying damp and treating dysentery and its preparing method and application

A heat-clearing and detoxifying, composition technology, applied in the field of medicine, can solve problems such as adverse reactions of chemical drugs, and achieve the effect of avoiding more adverse reactions, less toxic and side effects, and definite curative effect

Inactive Publication Date: 2006-11-08
HEILONGJIANG ZBD PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, most of the drugs used to treat dysentery are chemical drugs, such as norfloxacin, ciprofloxacin, amoxicillin, etc., and chemical drugs often have adverse reactions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1 The preparation of Chinese medicine composition capsule of the present invention

[0029] Take 25g of berberine hydrochloride, 375g of celandine, 375g of Pulsatilla chinensis, 375g of Qinpi, except for berberine hydrochloride, other celandine and other three herbs, decoct twice with water, 2 hours each time, combine the decoction, filter , the filtrate is concentrated to a thick paste with a relative density of 1.31 (50°C), let it cool, add three times the amount of 80% ethanol, stir well, let stand for 24 hours, filter, reclaim the ethanol, and concentrate to a relative density of 1.30 (50°C ) thick paste, add berberine hydrochloride and starch 150g, mix evenly, make granules, dry, pack into capsules and make 1000, to get final product.

Embodiment 2

[0030] Embodiment 2 The preparation of Chinese medicine composition oral liquid of the present invention

[0031] Take 22g of berberine hydrochloride, 350g of celandine, 400g of Pulsatilla chinensis, 400g of Qinpi, except for berberine hydrochloride, other celandine and other three-flavored medicinal materials, add water to decoct once, decoct for 2 hours, filter, and concentrate the filtrate to Thick paste with a relative density of 1.32 (50°C), let it cool, add three times the amount of 80% ethanol, stir well, let stand for 18 hours, filter, recover ethanol, concentrate to a thick paste with a relative density of 1.31 (50°C) , add berberine hydrochloride, and add an appropriate amount of water, adjust the pH value to 7.0, stir well, refrigerate (4-8°C) for 48 hours, filter, add 600g sucrose to the filtrate, stir to dissolve, then add an appropriate amount of essence and adjust the pH When the value reaches 7.0, add water to 2500ml, stir evenly, filter, fill, and sterilize. ...

Embodiment 3

[0032] Embodiment 3 The preparation of Chinese medicine composition tablet of the present invention

[0033] Take 20g of berberine hydrochloride, 300g of celandine, 450g of Pulsatilla chinensis, 300g of chrysanthemum bark, except for berberine hydrochloride, other celandine and other three-flavored medicinal materials, add water to decoct twice, 1.5 hours each time, combine the decoction, filter , the filtrate is concentrated to a thick paste with a relative density of 1.25 (50°C), let it cool, add three times the amount of 80% ethanol, stir well, let it stand for 28 hours, filter, reclaim the ethanol, and concentrate to a relative density of 1.25 (50°C ) thick paste, add berberine hydrochloride and starch to granulate, add magnesium stearate, mix well, and compress into tablets to obtain.

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PUM

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Abstract

The present invention provides a kind of Chinese medicine composition for clearing away heat and toxic matter, drying damp and treating dysentery and its preparation process and application. The Chinese medicine composition has effective components prepared with berberine hydrochloride, celandine, Chinese pulsatilla and ash bark in certain weight proportion. It is prepared into oral liquid, tablet, capsule or granule. The present invention also provides the application of the Chinese medicine composition in preparing medicine for treating diarrhea and dysentery caused by dampness and heat in the large intestine.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for clearing away heat and detoxification, drying dampness and stopping dysentery, and a preparation method and application thereof. Background technique [0002] At present, the drugs used to treat dysentery are mostly chemical drugs, such as norfloxacin, ciprofloxacin, amoxicillin, etc., and chemical drugs often have adverse reactions. There are few traditional Chinese medicines currently used to treat diarrhea and dysentery, and there are only a few kinds such as Gegen Qinlian Micro Pills and Compound Berberine Tablets. Contents of the invention [0003] (1) Technical problems to be solved [0004] The purpose of the present invention is to provide a traditional Chinese medicine composition for clearing away heat and detoxification, drying dampness and stopping dysentery, its preparation method and application. [0005] (2) Technical solut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61K31/4375A61P1/12
CPCY02A50/30
Inventor 方同华王春生
Owner HEILONGJIANG ZBD PHARMA
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