56 results about "Sample integrity" patented technology

An assay device, a fluid analyte sample separator device and methods for use of thereof for determining whether the integrity of a fluid analyte sample has been compromised and for contemporaneously assaying the sample for the presence or absence of multiple analytes, such as drugs of abuse. The device is composed of a housing having separate slots therein for insertion of one or more analyte test strips, one end of which protrudes from the housing, and one or more units of a sample integrity monitoring system. The device may be used in dipstick or cassette form. An analyte sample separator for division of sample and retention of uncontaminated sample for further testing is also provided. The analyte test strips and sample integrity monitoring system are replaceable, so that the panel of analytes and of sample condition parameters tested can be customized.

An assay device, a fluid analyte sample separator device and methods for use of thereof for determining whether the integrity of a fluid analyte sample has been compromised and for contemporaneously assaying the sample for the presence or absence of multiple analytes, such as drugs of abuse. The device is composed of a housing having separate slots therein for insertion of one or more analyte test strips, one end of which protrudes from the housing, and one or more units of a sample integrity monitoring system. The device may be used in dipstick or cassette form. An analyte sample separator for division of sample and retention of uncontaminated sample for further testing is also provided. The analyte test strips and sample integrity monitoring system are replaceable, so that the panel of analytes and of sample condition parameters tested can be customized.

Devices and methods for performing dielectrophoresis are described. The devices contain a sample channel which is separated by physical barriers from electrode channels which receive electrodes. The devices and methods may be used for the separation and analysis of particles in solution, including the separation and isolation of cells of a specific type. As the electrodes do not make contact with the sample, electrode fouling is avoided and sample integrity is better maintained.

Device, system and method for sampling of soft sediments with retention of sample material and profile. A barge is anchored and stabilized in position; sampling tubes are driven through underlying sediments using continuous and controllable translational pneumatic force; a torpedo-shaped end piece leads the sampling tubes into the sediments. Once at desired depth, a rotational force is applied to sampling tubes. Fins located around torpedo prevent the torpedo from rotating and connection between leading sampling tube and torpedo is tightened. O-ring located between torpedo and leading sampling tube is squeezed as a result of such tightening and bulges inward pinching the core inside sampling tube. During retrieval, core is more likely to break at the location of the pinch which has introduced structural discontinuity; core above the pinch is capped by compacted material at the pinch. O-ring does not disturb sample integrity during descent. Winch and pulley mechanism may assist.

Devices and methods for performing dielectrophoresis are described. The devices contain sample channel which is separated by physical barriers from electrode channels which receive electrodes. The devices and methods may be used for the separation and analysis of particles in solution, including the separation and isolation of cells of a specific type. As the electrodes do not make contact with the sample, electrode fouling is avoided and sample integrity is better maintained.

An improved biopsy kit for the collection, storage, transportation, and processing of biopsy tissue samples is disclosed. The disclosed biopsy kit consists of a typical specimen container and an improved tissue cassette with adhesively attached polyvinyl alcohol foam pads on both the base and lid portions. An excised tissue sample is sandwiched between the pads upon cassette closure, simultaneously isolating and securing the sample in its original orientation. Superior wicking, absorbency, and moisture retention rate of these polyvinyl alcohol pads allows maximum tissue fixation as well as maintains sample integrity. Once the tissue is placed by the physician at the patient's side, it remains there until the tissue is ready to be processed. This eliminates transfer errors as well as tissue loss.

An improved pipette tip (100) including an elongate body stretching between a proximal end (116) and a distal end (114). The body (112) is typically made from a plurality of layers (e.g. 130, 132, 134, 136, 138) configured and arranged to provide a fluid path extending from the distal end toward the proximal end. The improved pipette tip (100) includes a sensor component disposed to electrically interrogate fluid flowing along the fluid path. An operable sensor component includes an electrode (e.g. 154,192) that is disposed in the fluid path to contact fluid therein. A pipette tip (100) may be embodied to: count particles, verify sample integrity (e.g. freedom from bubbles), monitor sample flow rate, and confirm an inspired volume, among other uses.

Devices and methods for performing dielectrophoresis are described. The devices contain sample channel which is separated by physical barriers from electrode channels which receive electrodes. The devices and methods may be used for the separation and analysis of particles in solution, including the separation and isolation of cells of a specific type. As the electrodes do not make contact with the sample, electrode fouling is avoided and sample integrity is better maintained.

Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can include an additive system for adding an additive to a sample to reduce the adverse affects of bubbles and microbubbles in the sample. Some systems and methods disclosed herein include performing an auxiliary measurement cycle in the event of a failure of a scheduled measurement cycle. Some systems and methods disclosed herein include a measurement system configured for use with multiple patients.

An improved pipette tip (276) including an elongate body stretching between a proximal end (277) and a distal end. The body typically includes a plurality of thin film layers (e.g. 154, 156, 102, 158, 202) configured and arranged to provide a fluid path extending from the distal end toward the proximal end (277). The improved pipette tip (276) includes an interrogation zone in which to interrogate fluid flowing along the fluid path. One operable interrogation arrangement, generally (100), includes structure configured to permit detection of radiation resulting from a Stokes-shift. Optionally, a sensor component may include one or more electrode (e.g. 248, 250) that is disposed in the fluid path to contact fluid therein for electrically-based interrogation. A pipette tip (276) may be embodied to: count particles, verify sample integrity (e.g. freedom from bubbles), monitor sample flow rate, and confirm an inspired volume, among other uses.

A system for obtaining a representative sample of a natural gas stream, particularly a stream which is at or below its hydrocarbon dew point temperature (H.C.D.P.). The preferred embodiment of the present invention contemplates a sample cylinder having a flexible isolation barrier and integrated valving to provide a controlled ingress of sample gas at nominal pressure differential. The system thereby avoids throttling of the sample gas and the inherent cooling problems associated therewith when the stream is at or below hydrocarbon dew point temperature. The flexible isolation barrier of the present invention is relatively inexpensive and is configured for quick and easy replacement, which may be routinely performed to insure sample integrity. Alternative embodiments of the invention contemplate a spherical sample cylinder configuration with flexible isolation barrier, as well as an improvement for piston-type sample cylinders to provide constant sample pressure.

The invention discloses a lacustrine core sampling device for sediments in lakes with different depths. The lacustrine core sampling device comprises a handle rod, a drilling rod and a rotary core capturing device which are sequentially fixedly connected from top to bottom, wherein the rotary core capturing device comprises a sample pipe and a rotary blade, a sample pipe body is a semicircular groove body, a connecting rod connected with the drilling rod is arranged at the top end of the semicircular groove body, a drill bit is fixedly arranged on the outer side surface of the bottom end of the semicircular groove body, and two ends of the rotary blade are respectively rotatably connected to the top end and the bottom end of the semicircular groove body. According to the lacustrine core sampling device, the defect of an existing mechanical sediment sampler is overcome, the sampling success rate and the sample integrity are increased, lacustrine cores of water bodies and marshes in different depths are sampled through the arrangement of prolongable drilling rod and a hammer, the dismantling link is greatly simplified, the time is effectively saved, and the demand on research is also met.

The utility model relates to a tobacco rod / filter rod sampling system. The sampling system is provided with a plurality of gripper devices, and grips a plurality of tobacco rod / filter rod samples from an outlet channel through negative pressure suction and air cylinder motions; therefore, the utility model can simultaneously collect a or a plurality of tobacco rod / filter rod samples at one time, and convey the tobacco rod / filter rod samples gripped by the sampling system to an integrative test system through the level-transmission air cylinder without any damage to the samples; the sampling speed and sample integrality are far higher than manpower and any existing sampling method. The sampling system of the utility model conveys samples through mechanical method, and can convey samples with a long distance and free of damages; therefore, two or more tobacco rod / filter rod forming machines only need one integrative test system to complete the test task, thus the utilization rate of the integrative test system is improved and the production cost is reduced.

The invention discloses a thermal power equipment-based state early warning method. The method comprises the steps of obtaining historical data of n detected points, and performing sample extraction on the historical data by taking 1 / h as preset precision to obtain m learning samples; performing learning on the learning samples by utilizing a memory matrix to obtain an indication model; accordingto a quantity relationship of the detected points, the learning samples and the preset precision, calculating sample integrity of the memory matrix, and according to the sample integrity, changing a quantity of the learning samples to correct the indication model; and performing state early warning operation by utilizing the corrected indication model. According to the method, the state early warning accuracy of thermal power equipment can be improved; and a state of the thermal power equipment is subjected to objective and good evaluation. The invention furthermore discloses a thermal power equipment-based state early warning system, a computer readable storage medium and a thermal power equipment diagnosis apparatus, which have the abovementioned beneficial effects.

The invention relates to a scanning electrochemical microscope sample stage for testing a multi-standard sample strip electrolytic cell. The sample stage is formed by a Teflon carrier plate (the electrolytic cell at the upper end) and a U-shaped support. The left end wall and the right end wall of the electrolytic cell are respectively provided with a round hole for placing a counter electrode anda reference electrode respectively. The U-shaped support is fixed by screws with the carrier plate. Cylindrical small rods are riveted into the carrier plate in the positive direction and the negative direction of the X-axis and the positive direction of the Y-axis. The bottom surface is provided with a circular groove, the carrier plate at the center of the electrolytic cell is provided with a circular hole and the circular groove, a rubber gasket is placed in the groove, a test sample is placed on the rubber gasket, and then a metal pressing piece is placed. Bolts on the U-shaped support are adopted for fixation, and a probe is used for scanning the sample at the circular hole. The sample stage is simple and quick in sample preparation, convenient to remove and capable of testing multi-standard samples under the premise that the sample integrity is maintained. The tested sample can be reused for other test analysis, the application field of the SECM is expanded, and the utilizationrate is improved.

Methods, systems, and apparatus make a determination of a level of integrity of a sample of biomolecules. For example, the determination of the integrity of RNA in a sample may be done in a fast and reproducible manner, such that the user can be assured of accuracy of a test (e.g. quantitative polymerase chain reaction qPCR) on the sample and compare results of different samples. The determination of integrity of an RNA sample is performed by comparing a size profile to reference size profiles (degradation standards) obtained from degradation over different lengths of times. As the reference scale of the level of integrity is derived from the actual degradation that occurs in a sample, high accuracy, reproducibility, and efficiency is provided.

The invention discloses a multiple specific primer pair for assisting in identification and detection of alien invasive species of Pomacea canaliculata and Pomacea maculata and further discloses application of the multiple specific primer pair, aiming to overcome the difficulty in identifying and distinguishing Pomacea canaliculata and Pomacea maculata according to morphological characteristics because Pomacea canaliculata and Pomacea maculata are relative species with similar morphology. The specific primer pair is composed of DNA sequences expressed by a sequence 1, a sequence 2 and a sequence 3 of a sequence table. The specific primer pair can be applied to help to identity the alien invasive species of Pomacea canaliculata and Pomacea maculata molecularly without being affected by individual growth states or sample integrity, and has the advantages of high economic efficiency, convenience, accuracy and high sensitivity. The specific primer pair and the application thereof can be applied to plant protection departments and quarantine department in a wide scope and solves the problem about identification of the alien invasive species of Pomacea canaliculata and Pomacea maculata in China, which troubles the plant protection and quarantine departments for a long time.

The invention provides a sintering mould. The sintering mould comprises an outer sleeve, a bottom cover, a top cover, an upper mould, a lower mould, a lower graphite rod and an upper graphite rod, wherein the bottom cover and the top cover are respectively arranged at the bottom and the top of the outer sleeve; the lower mould is placed in a hollow cavity arranged on the outer sleeve and is placed on the bottom cover; the lower part of the upper mould is sleeved at the outer side of the lower mould and the lower graphite rod is inserted into a hollow cavity arranged in the lower mould; and the upper graphite rod is inserted into a hollow cavity arranged in the upper mould and is placed at the top of the lower graphite rod. The three components including the outer sleeve, the bottom cover and the top cover are in a separated design so that the loading of a sample and the replacing of a graphite mould are very easy. A cylindrical protection sleeve of the outer sleeve has the function of preventing from oxidizing the graphite mould at a high temperature, and also increases the compression strength of the graphite mould so as to improve the compression capability is improved by at least 1.5 times. The sample can be more easily taken out through a tapered round table design of the lower mould. When the sintering mould is used at the high temperature, a vacuum cavity does not need to be additionally arranged, a mould unloading process does not need to be forcedly processed, and the sample integrity is 100%, so that the service life of graphite is prolonged.

The invention discloses a lake bottom sediment sampling device which comprises an operation platform, a control device and a sampler, wherein the operation platform comprises a plurality of vacuum oil drums, a steel framework and a wood plate; every two adjacent vacuum oil drums are fixedly connected with each other through the steel framework; the wood plate is fixed on the steel framework; iron rings are fixed at four corners of the wood plate; the control device comprises a drill rig, a dill rod, a bracket, an auxiliary bracket, a pulley and a steel rope; the drill rig, the bracket and the auxiliary bracket are mounted on the midpoint on the upper surface of the wood plate; a sampling hole is formed in the midpoint of the wood plate; the upper end of the drill rod is connected with the steel rope; the steel rope is connected with a winch on the drill rig through the pulley; the lower end of the drill rod penetrates a fixing drill hole right above the sampling hole. The lake bottom sediment sampling device has the advantages that the limitation of a channel is avoided; the cost is low; the efficiency is high; the integrity of a sample is high; disassembly and assembly are fast; on-land towing to any water body for sampling is realized; the sampler is high in strength, and excellent in corrosion resistance and compression resistance.

A system for obtaining a representative sample of a natural gas stream, particularly a stream which is at or below its hydrocarbon dew point temperature (H.C.D.P.). The preferred embodiment of the present invention contemplates a sample cylinder having a flexible isolation barrier and integrated valving to provide a controlled ingress of sample gas at nominal pressure differential. The system thereby avoids throttling of the sample gas and the inherent cooling problems associated therewith when the stream is at or below hydrocarbon dew point temperature. The flexible isolation barrier of the present invention is relatively inexpensive and is configured for quick and easy replacement, which may be routinely performed to insure sample integrity. Alternative embodiments of the invention contemplate a spherical sample cylinder configuration with flexible isolation barrier, as well as an improvement for piston-type sample cylinders to provide constant sample pressure.

An improved pipette tip (100) including an elongate body stretching between a proximal end (116) and a distal end (114). The body (112) is typically made from a plurality of layers (e.g. 130, 132, 134, 136, 138) configured and arranged to provide a fluid path extending from the distal end toward the proximal end. The improved pipette tip (100) includes a sensor component disposed to electrically interrogate fluid flowing along the fluid path. An operable sensor component includes an electrode (e.g. 154, 192) that is disposed in the fluid path to contact fluid therein. A pipette tip (100) may be embodied to: count particles, verify sample integrity (e.g. freedom from bubbles), monitor sample flow rate, and confirm an inspired volume, among other uses.

The invention discloses a thick sludge depth-setting sampler and a sludge depth-setting sampling method, belongs to the technical field of sludge sampling devices and methods, and aims to solve the problem that an existing sampler is not suitable for thick sludge depth-setting sampling. The thick sludge depth-setting sampler is characterized in that a clamping plate with a clamping hole, which ishinged at the top end of a sampling tube, is fastened and clamped with a first fastening section / second fastening section on a pulling rod, so that an opening-closing state of the bottom end opening of the sampling tube is controlled during a process of inserting the sampler into determined depth of the sludge layer and an inserting and sampling process at determined depth. The sampler is simple in structure, is low in producing and manufacturing cost, is convenient to use, is suitable for depth-setting sampling under a thick sludge environment, and is precise in sampling, and the sampled sample is good in integrity and is good in representativeness. The invention correspondingly discloses the sludge depth-setting sampling method applying the sampler, and the method is simple in step, andis suitable for depth-setting sampling under the thick sludge environment.

The invention discloses a primer pair and a kit for identification or assisted identification of stored bean weevils. The primer pair disclosed by the invention is composed of the following five primer pairs: a primer pair 1 (a sequence 1 and a sequence 2), a primer pair 2 (a sequence 3 and a sequence 4), a primer pair 3 (a sequence 5 and a sequence 6), a primer pair 4 (a sequence 7 and a sequence 8) and a primer pair 5 (a sequence 9 and a sequence 10). Used for identification of species of the stored bean, the kit is not affected by the individual development status of a sample and the integrity of the sample, and has the advantages of being time-saving, high-efficient and accurate; and the primer pair and the kit can be widely applied to the food storage departments and quarantine departments.

This disclosure reveals a combination of embodiments that increase the evaporation rate of liquid solutions when subjected to blow-down gas flows. Certain gas flow separator baffles or framed inserts with vanes may be especially effective to enhance evaporation when combined with aggressive blow-down flow rates and centrifugal force. The centrifugal force applied to the evaporating liquid protects sample integrity by preventing the solution(s) from splashing out of the drying container. Such splashing, when high blow-down gas flow rates are directed into the sample containers, affects yield and purity.

The invention discloses a specific primer pair for assisting booklice identification and application thereof. The specific primer pair provided by the invention is composed of DNA shown as a sequence 1 in a sequence table and DNA shown as a sequence 2 in the sequence table. The specific primer pair disclosed by the invention can be used for assisting the booklice identification from a molecular level, is free from influences of sample ontogenesis state and sample integrity, and has the advantages of high efficiency, rapidness and accuracy. According to the invention, the booklice variety identification problem which puzzles the stored grain protection and port quarantine departments for a long time is solved. The specific primer pair disclosed by the invention can be widely applied to thegrain storage department and the quarantine department.

Reagents and methods for using automated laboratory equipment to determine whether the specific gravity of a urine sample is out of normal range as an indication of adulteration. The sodium (Na+) and potassium (K+) normally found in a urine sample can be used as markers. A sodium-potassium dependent β-galactosidase can be utilized with o-nitrophenylgalactoside (o-NPG) which is cleaved into o-nitrophenol, which turns the sample yellow. The sample can be analyzed by spectrophotometry methods utilized in most clinical analyzers at a pre-determined primary wavelength to obtain a Specific gravity Index (SGI). Measurements of the SGI that are outside a known normal range can indicate that the sample integrity has been compromised.

The invention discloses a preparation method of a low-temperature sintering nanosilver paste heat conductivity testing sample. The preparation method comprises the following steps of preparing nanosilver paste; adhering a circular die onto a heat release adhesive tape, and filling the nanosilver paste into the whole die; drying an organic solvent in the nanosilver paste; pressing the nanosilver paste on a worktable, and continuing to fill the nanosilver paste until the nanosilver paste is fully filled into the whole die; pressing again until the nanosilver paste is fully filled into the die; removing the heat release adhesive tape, adhering the other surface of the die to a new heat release adhesive tape, and pressing until the nanosilver paste is fully filled into the die; removing the heat release adhesive tape, and sintering the semi-dry nanosilver paste at low temperature; grinding the sample, until the testing sample meeting the testing size requirement is formed. The preparation method has the advantages that the sample meeting the testing requirement is met; after the nanosilver paste is sintered, the structure is denser, and the mechanical strength and heat conduction property of the sample are improved; by using the heat release adhesive tape, the adhering with the nanosilver paste is avoided, and the sample integrity is better.

The invention discloses a method for improving accuracy of determination of water content of crude oil, and the method comprises the following steps: step B, a distillation solvent is added into a heating bottle and stirred; step C, the crude oil is put into a crude oil homogenization system; step A, the heating bottle, an exhaust pipe and a condenser are connected in sequence; step D, a condenser pipe is communicated with the exhaust pipe by a connecting pipe, and an electromagnetic valve is arranged on the connecting pipe; step E, a liquid level sensor is installed in the condenser; and step F, the electromagnetic valve and the liquid level sensor are respectively connected with a controller. The crude oil is first homogenized, the evenly-mixed crude oil can effectively avoid bumping accidents in the heating distillation process; in the distillation process, the controller adjusts the working state of the electromagnetic valve to distribute oil and gas distilled in the heating bottle to the connecting pipe and the condenser pipe so as to avoid products obtained by the distillation to rush out the condenser and avoid bumping and sample rushing, and sample integrity and the accuracy of the determination of the water content of the crude oil can be ensured.

The invention relates to a device and a method for accurately sampling plating solution in a plating pot in a hot plating production line. The device comprises a frame (6) positioned on the plating pot (18), wherein one end of the frame (6) is provided with a No.1 asynchronous motor (5); the No.1 asynchronous motor (5) drives a No.1 sliding block (11) to drive a No.2 sliding block (12) to do reciprocating motion on a track (7) by driving a screw rod (8) to rotate; a No.2 asynchronous motor (14) drives a sampler (9) and a sealer (10) to descend to or ascend from the plating solution (19) through a driver (13); the sealer (10) opens or closes a spoon gate (9.1) of the sampler (9) under the drive of a cylinder (16); and the No.1 asynchronous motor (5), the No.2 asynchronous motor (14), an air compressor system (2) and an electromagnetic valve (4) are connected with an electronic control system. The device can accurately samples the plating solution at each point in the plating pot, avoids manual sampling errors and ensures sampling integrity, consistency and repeatability.

An improved pipette tip (276) including an elongate body stretching between a proximal end (277) and a distal end. The body typically includes a plurality of thin film layers (e.g. 154, 156, 102, 158, 202) configured and arranged to provide a fluid path extending from the distal end toward the proximal end (277). The improved pipette tip (276) includes an interrogation zone in which to interrogate fluid flowing along the fluid path. One operable interrogation arrangement, generally (100), includes structure configured to permit detection of radiation resulting from a Stokes-shift. Optionally,a sensor component may include one or more electrode (e.g. 248, 250) that is disposed in the fluid path to contact fluid therein for electrically-based interrogation. A pipette tip (276) may be embodied to: count particles, verify sample integrity (e.g. freedom from bubbles), monitor sample flow rate, and confirm an inspired volume, among other uses.