18 results about "Platinum nanoclusters" patented technology

The invention relates to the technical field of mycotoxin rapid detection, in particular to an electrochemical luminescence sensor for citrinin detection and a detection method of the citrinin. A sensing substrate of the sensor is prepared by loading platinum nanoclusters (Pt NCs) on a NiCo-LDH / MXene composite substrate through an in-situ growth strategy; the high conductivity of MXene and the LDH confinement effect are utilized to synergistically promote three-dimensional exposure of Pt active sites, the efficiency of generating active oxygen through electro-catalysis is remarkably enhanced, and a light-emitting signal is improved. And a CRISPR / Cas12a system is further integrated, so that a regulation mechanism of recognition-cutting-signal de-suppression is realized, and food matrix interference is effectively avoided. And a new technology is provided for monitoring the fungaltoxin by combining a dual enhancement mechanism of material catalytic optimization and enzymatic signal amplification.

This invention relates to rare-earth single-atom doped alumina-supported platinum cluster catalysts, their preparation methods, and applications. The catalyst comprises a catalyst support and platinum nanoclusters dispersed on the catalyst support. The catalyst support is an alumina support doped with rare-earth elements in single-atom form. The preparation method includes the following steps: Step 1: preparing a rare-earth-aluminum composite metal oxide precursor; Step 2: preparing a catalyst support; Step 3: loading platinum onto the catalyst support; Step 4: activating the platinum-supported catalyst support. The catalyst is applied in the dehydrogenation reaction of cycloalkane. This invention, by precisely doping rare-earth elements into the alumina lattice in single-atom form, constructs stable rare-earth-oxygen active sites within the lattice, significantly promoting the migration and diffusion of hydrogen atoms from the platinum clusters to the support surface, thereby greatly enhancing the hydrogen spillover effect, improving the utilization efficiency of active hydrogen, and achieving precise control over complex reaction pathways.

The invention provides an artificial neural network potential energy function development method for simulating a dynamic process of a molecular sieve packaged platinum cluster in an oxygen environment, which comprises the following steps of: performing potential energy surface sampling on a system of a Silicalites molecular sieve packaged platinum nanocluster and O2 and Pt-O structures by using a random surface walking global optimization method of LASP software; a part of structures are randomly extracted from a data set obtained through sampling, VASP software is used for structural optimization, and the obtained structures and data such as energy and force of the structures are added into a DFT training set. Neural network training is carried out on the DFT data set by means of machine learning, and an artificial neural network potential energy function G-NN is obtained; the artificial neural potential energy function obtained by training not only meets the expectation in calculation precision, but also has the advantage of magnitude order in calculation speed, and overcomes the defects of traditional molecular dynamics in calculation systems and calculation speed.

The invention discloses a primer group for detecting methicillin-resistant staphylococcus aureus, a kit and application, and relates to the technical field of detection. The invention provides a primer group and a kit for detecting methicillin-resistant staphylococcus aureus. The primer group comprises F3, B3, FIP and BIP; the detection method comprises the steps of enrichment of target bacteria, nucleic acid extraction, loop-mediated isothermal amplification, amplification signal reading and data analysis, and belongs to the technical field of biological detection. Specific primers are designed for highly conservative mecA gene sequences of the methicillin-resistant staphylococcus aureus, a novel loop-mediated isothermal amplification signal reading form is constructed on the basis of cationic platinum nanoclusters (CS-PtNCs), and dual-mode detection of the methicillin-resistant staphylococcus aureus in a sample can be achieved within one hour. Qualitative detection and quantitative detection are realized, and the kit has the characteristics of high sensitivity and high portability.

The application belongs to the technical field of food detection, and particularly relates to a gas-sensitive composite material for detecting triethylamine, a preparation method, a gas sensor and application. The unique composite structure of the porous zinc oxide carrier and the ultrafine platinum nanocluster is constructed, and the synergistic effect of the two is utilized, so that the adsorption, catalysis and electronic modulation performance for triethylamine gas are significantly improved. The gas sensor has the characteristics of high sensitivity with a detection range of 0.1ppm-50ppm, a low detection limit of 37.5ppb, excellent selectivity and rapid response, and is particularly suitable for fields such as food freshness monitoring.

The application discloses a urine detection method based on platinum ultra-nanoparticles responding to hypoxia and application thereof. The platinum ultra-nanoparticles PNCA are formed by covalently connecting the ultra-small platinum nanoclusters after amination with 4,4'-dicarboxylic azobenzene azo responding to hypoxia through EDC / NHS reaction, and after wrapping the nanoparticles with a layer of hyaluronic acid HA, the nanoparticles can specifically target tumor sites. Then, under the action of the hypoxia environment reductase in the tumor site, the PNCA nanoparticles can be reduced and degraded into many small PtNCs, re-entering the blood circulation, and since the particle size is less than the critical value 5.5 nm that can be removed by the kidney, the nanoparticles can be excreted from the kidney to the urine for disease state detection. Due to the excellent hypoxia response effect of the PNCA nanoparticles and the high kidney removal effect of the PtNCs, the application has obvious advantages in in vivo application.

The application discloses a kind of platinum supported cerium-based nanoscale enzyme and its preparation and application, the nanoscale enzyme includes cerium oxide nanorod carrier and the Pt active component loaded on its surface, the Pt active component is dispersed in the form of single atom or nanocluster on the surface of cerium oxide nanorod, the surface of cerium oxide nanorod has oxygen defect, by first loading platinum monolayer on the surface of cerium dioxide nanorod, then by reduction treatment, platinum atom forms platinum nanocluster on the surface of cerium dioxide and obtains.The nanoscale enzyme of the application effectively adjusts the oxygen vacancy and Pt site on the surface of cerium dioxide, has good peroxidase-like characteristics, can be used to construct TMB colorimetric system for colorimetric analysis of thiol reducing substances, and further used for disease screening, significantly improves the distinguishing effect.

The invention discloses a large-scale synthesis method of metal platinum nanoclusters based on electrochemistry, which belongs to the technical field of metal nanocluster synthesis and comprises the following steps: preparing a Pt source on carbon paper; producing hydroxyl groups and defects on the carbon paper or ALK film or GDE based on electrochemical oxidation and reduction reactions; and depositing the Pt nanocluster on the carbon paper or the ALK film or the GDE through a constant-current electrolytic reaction. The carrier with hydroxyl and defects is used as a working electrode, the Pt source is used as a counter electrode for electrolytic reaction, the Pt nanocluster with small particle size and uniform metal distribution is prepared and synthesized in a green, clean and large-scale manner by using an electrochemical method under the room temperature condition in an electro-deposition manner, the reaction condition is mild, heating is not needed, the operation is simple and convenient, and the method is suitable for industrial production. The product is easy to separate, and the carbon-supported metal platinum nanocluster catalyst is easy to recover. The whole synthesis process does not need to use toxic and dangerous organic reagents, the reaction efficiency and the yield are high, and mass production in the industry can be realized.

The invention relates to the technical field of biosensing and nanomaterials, in particular to a trypsin fluorescent probe based on human serum albumin-platinum nanoclusters and a preparation method and application of the trypsin fluorescent probe. The preparation method comprises the following steps: mixing a human serum albumin aqueous solution and a chloroplatinic acid aqueous solution, carrying out a first reaction under an alkaline condition, adding a sodium borohydride aqueous solution, carrying out a second reaction, and dialyzing after the reaction is completed to obtain the fluorescent platinum nanocluster probe, the fluorescent platinum nanocluster probe is the trypsin fluorescent probe based on the human serum albumin-platinum nanocluster. The probe can cause damage to the structure of the platinum nanocluster through specific degradation of a protein template on trypsin, so that fluorescence quenching of the platinum nanocluster is caused, and sensitive detection on the trypsin is realized.

The invention relates to the technical field of biosensing detection, and provides an enzyme cascade dual-mode sensor as well as a preparation method and application thereof. The sensor comprises a three-dimensional (3D) PCN / BS-rGO carrier, PtAuNCs (PtAuNCs) loaded on the 3D PCN / BS-rGO carrier, and Enzyme fixed on the carrier. The invention further discloses a preparation method of the sensor. According to the enzyme cascade dual-mode sensor, the electron transfer rate is increased by constructing the three-dimensional carrier and doping B, S and P, the platinum nanoclusters PtAuNCs are loaded on the three-dimensional carrier, and due to the aggregation-induced emission effect of the PtAuNCs and the carrier, the fluorescence intensity of the PtAuNCs is greatly improved; the natural enzyme is loaded on the nano composite material, so that the stability of the immobilized enzyme is improved, the loss of an intermediate product of an enzyme cascade reaction is reduced, the enzyme cascade reaction is accelerated, and the efficiency of the enzyme cascade reaction is improved.

This invention relates to a fluorine and chlorine co-doped carbon nanosheet-supported platinum nanoclusters hydrogen evolution catalyst and its preparation method. The catalyst consists of a fluorine / chlorine co-doped two-dimensional carbon nanosupport, platinum nanoclusters supported on its surface, and nitrogen-containing organic ligands. The preparation process includes: using an alkali metal chloride as a template and a chlorine source, and a fluorine-containing polymer as a carbon-fluorine dual source, a layered carbon support is obtained through high-temperature calcination, grinding, and washing; platinum nanoclusters are loaded into a composite structure using a wet chemical method; and nitrogen-containing organic ligands are introduced into an acidic electrolyte to achieve in-situ surface modification. The core innovation of this invention lies in optimizing the hydrogen adsorption energy of the platinum clusters through electronic regulation of the support, while simultaneously utilizing organic ligands to reconstruct the interfacial hydrogen bond network, synergistically improving proton transfer efficiency and electrochemical stability. The resulting catalyst can be directly used as the cathode of a proton exchange membrane electrolyzer, exhibiting a significantly reduced hydrogen evolution overpotential and excellent long-term stability in an acidic environment. It also avoids the use of binders and significantly improves the utilization rate of noble metal atoms, effectively reducing the cost of platinum-based hydrogen production catalysts.

The invention discloses a Pt nanocluster catalyst capable of resisting atom redispersion as well as a preparation method and application of the Pt nanocluster catalyst, and belongs to the technical field of catalysts. Uniformly mixing cerium dioxide and water to obtain a first mixed solution; mixing a platinum-containing precursor material with the first mixed solution to obtain a second mixed solution; performing rotary evaporation on the second mixed solution by using a rotary evaporator to obtain solid powder; calcining the obtained solid powder in the air at 700-900 DEG C to obtain a Pt / CeO2 catalyst precursor; and reducing the Pt / CeO2 catalyst precursor in a reducing atmosphere at 250-350 DEG C to obtain the Pt nanocluster catalyst. The average size of the Pt nanocluster is 1.0-1.5 nm, and high-temperature calcination of the Pt nanocluster can effectively inhibit in-situ atoms of the Pt nanocluster from being re-dispersed into Pt single atoms in a CO oxidation reaction. The catalyst shows excellent CO oxidation activity on the premise of keeping the Pt nanocluster structure.

This invention discloses a method for synthesizing platinum nanoclusters (ZIF-8@PtNCs) based on ZIF-8 encapsulation, and its application in the quantitative detection of doxycycline hydrochloride (Dox). Using acidic medium bleaching blue B as a stabilizer, potassium hexachloroplatinate as a raw material, and sodium borohydride as a reducing agent, a fluorescent platinum nanoclusters (PtNCs) are obtained after a mixed reaction. Then, ZIF-8 is synthesized in the PtNCs solution, allowing PtNCs to assemble onto ZIF-8, forming ZIF-8@PtNCs. The synthesized ZIF-8@PtNCs have a maximum excitation wavelength of 323.0 nm and a maximum emission wavelength of 450.0 nm. The fluorescence intensity and fluorescence stability of the prepared ZIF-8@PtNCs are improved compared to traditional PtNCs. The fluorescence intensity of ZIF-8@PtNCs is quenched upon the addition of Dox. Based on the linear relationship between the fluorescence intensity quenching value of ZIF-8@PtNCs and the Dox concentration, the Dox content can be detected. The method for synthesizing ZIF-8@PtNCs in this invention is simple and easy to achieve on a large scale. Its application in the detection of Dox is simple and low-cost, and it has potential application value in the detection of Dox content in water samples.

The invention discloses a monolithic catalyst for hydrogen production through hydrolysis of ammonia borane, and a preparation method and application thereof. The monolithic catalyst comprises a titanium foil substrate; the iron-doped titanium dioxide nano array is formed on the titanium foil substrate, and iron is dispersed in a monatomic form; the iron-doped titanium dioxide nano array is loaded on the substrate, and the platinum nano cluster is loaded on the iron-doped titanium dioxide nano array; and a Pt-O-Fe bond is formed between the platinum nanocluster and the iron-doped titanium dioxide nano array. The monolithic catalyst provided by the invention can efficiently catalyze ammonia borane hydrolysis for hydrogen production at normal temperature, has high conversion efficiency, very high catalytic activity and stability, and is a catalyst with great development prospects.

The application belongs to the cross field of nanomaterials and coordination chemistry, and specifically discloses a fluorescent silver-platinum nanocluster material, a preparation method and application as a mercury ion detection probe in mercury ion detection. 162 H 156 Ag 14 Cl4P 12 Pt, which is abbreviated as Ag 14 Pt(Dppp)6Cl4, belongs to a monoclinic system; a space group is P21 / c, alpha=90 degrees, beta=112.279(4) degrees, gamma=90 degrees, and a molecular weight is 4321.57 Da. The preparation method provided by the application does not need a complex process flow, and synthesis is carried out at normal temperature and pressure, the operation steps are simple, and raw materials are easy to obtain. The fluorescent silver-platinum nanocluster material has high stability, an electrochemical energy gap is as high as 1.53 V, can be stored for at least 30 days under normal temperature and pressure conditions, shows excellent fluorescence selectivity and sensitivity to mercury ions, and has good application prospect.

The invention aims to provide a preparation method and application of a gouty arthritis diagnosis and treatment integrated bionic nanoprobe, and belongs to the technical field of life medicine and inorganic nanomaterials. An alloy structure formed by gold-platinum nano-clusters is constructed through a chemical reduction method to serve as an inner core of the nano-clusters, and the exterior of the nano-clusters is coated with an erythrocyte membrane to obtain the gold-platinum nano-clusters. The nanoprobe coats an erythrocyte membrane, and is long in cycle half-life period and high in safety. The nanoprobe has uricase-like activity and catalase-like activity, can degrade hydrogen peroxide as a byproduct of uric acid while degrading uric acid, and relieves oxidative stress damage. The enzyme-like activity can be improved through in-vivo and in-vitro mild photothermal therapy, and the treatment effect of the probe on acute gouty arthritis is comprehensively improved.

The invention discloses a metal ceramic composite material for preparing hydrogen-rich water and preparation and application of the metal ceramic composite material. The composite material is of a porous structure and is prepared by mixing, forming and sintering raw materials; the raw materials comprise a nano metal phase, doped aluminum-based alloy particles, a ceramic matrix, a functional additive, a pore forming agent and a sintering additive in a weight ratio of (10-30): (10-30): (30-60): (5-15): (5-10): (2-5); the nano metal phase is magnesium-nickel alloy particles coated with zinc oxide; the doped aluminum-based alloy particles are aluminum-gallium-indium alloy of which the surfaces are loaded with platinum nano-clusters; the functional additive is hydrophilic graphene quantum dots. The composite material is high in catalytic activity, capable of releasing hydrogen for a long time and firm in surface bonding, and the problems that a traditional material is limited in hydrogen production efficiency, short in service life and poor in reaction controllability, and powder is prone to falling off from the surface of the material are solved.

The invention discloses a preparation method of a tungsten oxide-loaded platinum nanocluster catalyst containing oxygen vacancy, which comprises the following steps: dispersing tungsten chloride in absolute ethyl alcohol, performing ultrasonic stirring to fully dissolve the tungsten chloride, transferring the tungsten chloride to a polytetrafluoroethylene hydrothermal kettle, pouring out supernate after the reaction is finished, and drying to obtain the tungsten oxide-loaded platinum nanocluster catalyst containing oxygen vacancy. Centrifugally washing the product with deionized water and absolute ethyl alcohol, and drying in a drying oven to obtain tungsten oxide; the preparation method comprises the following steps: dissolving tungsten oxide in deionized water, stirring for a period of time, dissolving and dispersing metal precursor salt of platinum, slowly dropwise adding into the solution, and stirring for reaction; after the reaction is finished, centrifuging the solution, and drying the obtained solid to obtain a solid product; and calcining the solid product in an inert atmosphere to obtain a final product. According to the invention, efficient and stable preparation of the electrolytic water hydrogen evolution catalyst is realized; the obtained catalyst is a tungsten oxide loaded Pt nanocluster electrocatalyst, and the catalyst is uniformly dispersed and is a good water electrolysis hydrogen evolution catalyst.