2results about How to "Large Stokes shift" patented technology

This invention discloses indole-fused hydrogenated morpholino compounds, their preparation methods, and applications, belonging to the technical fields of fluorescent materials and antitumor compounds. Using enamine ketones and amines as reaction substrates, a series of indole-fused hydrogenated morpholino compounds with different substituents were synthesized in highly polar solvents via the Stork enamine reaction and intramolecular acylation reaction. These compounds exhibit fluorescence wavelengths in the range of 430-700 nm and show certain inhibitory activity against lung cancer A549, breast cancer MDA-MB-231, colon cancer HCT116, liver cancer HepG2, and prostate cancer DU145, providing more options for the preparation of tumor drugs.

The invention discloses a boron difluoride compound capable of realizing long-wavelength absorption and a preparation method of the boron difluoride compound. The boron difluoride compound is a compound with a structure as shown in a formula (I) or a salt of the compound. Compared with the traditional boron dipyrromethene dye, the boron difluoride compound has larger Stokes shift, and shows potential application value in the fields of cell detection, biomarkers and the like. # imgabs0 #