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81 results about "Entire cell" patented technology

Pinpointing single molecule positions with in situ point spread function retrieval for three dimensional nanoscopy of whole cells and tissues

ActiveUS12210167B2Image enhancementImage analysisPupil functionEntire cell
A method of in situ point spread function (PSF) retrieval is disclosed which includes encoding 3D location of molecules into PSFs, receiving molecule-generated images containing PSFs, segmenting the images into sub-PSF, initializing template PSFs from a pupil function, determining a statistical measure of a predetermined function between the sub- and template PSFs, associating each of the sub-PSFs with a template PSF, aligning and averaging the sub-PSF, applying a phase retrieval algorithm to the averaged sub-PSFs to update the pupil function, regenerating the template PSFs, repeating until a difference between a new and a prior generation pupil function is below a predetermined threshold, generating in situ PSFs from the last pupil function, and applying a maximum likelihood estimation algorithm based on the in situ PSFs and the sub-PSF to thereby generate lateral and axial locations of molecules.
Owner:PURDUE RES FOUND

Solar photovoltaic module

The utility model provides a solar photovoltaic module, and belongs to the technical field of solar photovoltaic module manufacturing. The solar photovoltaic module comprises a plurality of battery strings, each battery string comprises a plurality of small battery pieces, the edges of the small battery pieces are sequentially stacked and distributed, the small battery pieces are electrically connected, each small battery piece is obtained by cutting a whole battery piece, and in the extending direction of the battery strings, the number of the small battery pieces is larger than that of the adjacent small battery pieces. The non-cutting edge of the previous small battery piece is located above the cutting edge of the next small battery piece, and the non-cutting edge of the previous small battery piece is located on the light receiving side of the photovoltaic module. The photovoltaic module with the specific structure can effectively improve the power generation efficiency of the photovoltaic module, and has the advantages of short research and development period, low research and development cost and the like.
Owner:HUANSHENG NEW ENERGY (JIANGSU) CO LTD

Liquid circulation module

The utility model discloses a liquid circulation module to solve the problems that an existing cell culture device cannot accurately simulate an in-vivo dynamic circulation process, cross contamination occurs in a conventional cell culture experiment process, and an experiment result is inaccurate. The system comprises two liquid storage tanks, two pressure pumps and a cell culture device which is matched with the two liquid storage tanks for use, during use, liquid is driven by the pressure pump to flow, so that the liquid flows from the first liquid storage tank to the second liquid storage tank after passing through the flowmeter, the cell culture device and the one-way valve according to a set flow rate, liquid is quickly supplemented from the second liquid storage tank to the first liquid storage tank after being cultured for a period of time, and the process is repeated, so that the long-term dynamic circulating culture process of cells is realized; the device is simple in overall structure and convenient to use, the in-vivo dynamic circulation process can be accurately simulated in the cell culture process, cross contamination in the conventional cell culture experiment process is avoided, and therefore the accuracy of the experiment result is improved; the whole cell culture process is in a sealed state, so that the pollution problem is avoided.
Owner:MICRONANO CUBE TECH (BEIJING) CO LTD

Evaluation method, device and system of tumor intervention small molecule effect and storage medium

The invention provides a method, device and system for evaluating the effect of intervening small molecules by tumors and a storage medium, and relates to the technical field of bioinformatics, the method comprises the following steps: obtaining a first transcriptome representation of a tumor cell population before target small molecule intervention and a second transcriptome representation of a normal tissue cell population corresponding to the tumors; inputting the first transcriptome representation and the condition vector into a prediction model to obtain a third transcriptome representation; calculating a first distance and a second distance; an intervention effect is evaluated based on a comparison of the first distance and the second distance. According to the method, the influence of the drug on the transcriptome of the whole cell population is efficiently predicted, and the distance between the transcriptome and the health state is quantitatively compared, so that a set of brand new standard for improving the evaluation target from the traditional'killing cell 'to'reversing disease state' is established, and an objective decision basis is provided for developing more accurate drugs.
Owner:ACADEMY OF MILITARY MEDICAL SCIENCES

Communication method and device

A communication method and apparatus, comprising: a network device sends a plurality of first synchronization signal blocks to cover a whole cell through a plurality of first beams with a relatively large coverage range, thereby reducing the number of beams covering the whole cell, and reducing the period of beam scanning. And then sending the SIB1 corresponding to the plurality of first synchronization signal blocks, so that the terminal equipment sends the first random access signal on the first random access channel opportunity RO indicated by the SIB1. After a first target RO receives a first random access signal from a first terminal device, a first target beam corresponding to the first terminal device having an access requirement is determined from a plurality of first beams, and then the coverage range of the first target beam is scanned through a plurality of second beams with relatively small coverage ranges. On the basis of meeting the access requirement of the terminal equipment, the coverage area needing to be scanned is reduced, and the beam scanning resource overhead and the access time delay of the terminal equipment are reduced.
Owner:CHENGDU HUAWEI TECH CO LTD

Battery cell cover plate, cover plate assembly and battery cell

The present invention relates to the technical field of power batteries, and provides a battery cell cover plate, a cover plate assembly and a battery cell, the battery cell cover plate comprises: a cover plate body having two plate surfaces arranged back to back in the thickness direction of the cover plate body, one of the plate surfaces forming a support surface; the pole hole penetrates through the cover plate body; the supporting convex hull is arranged on the supporting surface in a protruding mode, and the height H1 of the supporting convex hull protruding out of the supporting surface meets the condition that H1 is larger than or equal to (H + 1.0 mm) and smaller than or equal to (H + 2.0 mm); wherein H is the height of the pole protruding out of the supporting surface. When the upper surface of the whole battery pack is impacted by external force, the impact force can be borne by the supporting convex hulls, direct stress of the pole columns is avoided, the short-circuit risk of the battery cell is reduced, the impact external force borne by the supporting convex hulls can be directly dispersed to the cover plate body and even the whole shell of the battery cell, the supporting performance of the shell of the battery cell is exerted, and the mechanical strength of the whole battery pack is improved; and long-term stable operation of the battery cell is ensured. And the supporting convex hulls can also improve the heat dissipation effect of the battery cell and improve the quick charging performance of the battery cell.
Owner:SVOLT ENERGY TECHNOLOGY CO LTD

Hydrogen production system

A hydrogen production system (10) includes: cell stacks (91), (92), (93) to produce hydrogen by electrolyzing water using supplied power; and a control unit (14). The control unit (14) controls at least one specific cell stack of the cell stacks (91), (92), (93). The control unit (14) selectively executes a load adjustment control to adjust a voltage or current of the power supplied to the specific cell stack, based on the amount of hydrogen production required for the entirety of the cell stacks (91), (92), (93), and an ON / OFF control to turn ON or OFF the power supplied to the specific cell stack.
Owner:DENSO CORP

Culture medium and culture method for stem cell-like memory T lymphocytes

The present invention relates to the field of cell culture, and in particular to a culture medium and a culture method for stem cell-like memory T lymphocytes. By adding a GSK-3β inhibitor, an mTOR inhibitor or a PI3K inhibitor, as well as adding IL-15 and using magnetic bead sorting, the present invention can provide a large number of stem cell-like memory T lymphocytes with memory characteristics and low differentiation status, which can be used alone for tumor treatment, or as a basic cell for CAR-T treatment to obtain better anti-tumor ability and survival and proliferation ability than central memory lymphocytes or effector lymphocytes in clinical practice, which has great significance and value to the entire field of cell research and application.
Owner:CYTOCRAFT BIOPHARMACEUTICAL CO LTD

Cell enriching and dyeing integrated equipment

The invention discloses cell enriching and dyeing integrated equipment which comprises a base; the enrichment assembly is arranged on the base and is used for enriching target cells; the dyeing assembly is arranged on the base and is used for dyeing target cells; the liquid adding assembly comprises a first guide rail arranged on the base, a first liquid adding pipe and a second liquid adding pipe, the first liquid adding pipe and the second liquid adding pipe are in sliding fit with the first guide rail, the first liquid adding pipe is used for adding a first reagent to the enrichment assembly, and the second liquid adding pipe is used for adding a second reagent to the dyeing assembly. The enrichment assembly and the dyeing assembly are integrated on the same base, the liquid adding assembly with the first liquid adding pipe and the second liquid adding pipe which can slide along the guide rail is arranged, the guide rail design of the liquid adding assembly ensures the accuracy and repeatability of liquid adding, mechanical operation of reagent adding is achieved, and the reagent adding efficiency is improved. The time and steps for manually taking and placing the reagent are obviously reduced, so that the efficiency of the whole cell enrichment, dyeing and subsequent identification process is effectively improved.
Owner:QINGDAO YANDING BIOMEDICAL TECHNOLOGY CO LTD

Battery liquid injection device and battery liquid injection method

The invention provides a battery liquid injection device and a battery liquid injection method, and relates to the technical field of batteries. The battery liquid injection device comprises a shell, a liquid injection pipe and a vacuumizing assembly, the shell is provided with a cavity, and the shell is configured to be arranged at an opening of a battery cell of a battery to be injected in a sealed and sleeved mode, so that the cavity is communicated with the interior of the battery to be injected. The liquid injection pipe comprises a liquid injection port and a liquid outlet, the liquid injection pipe penetrates through the shell and extends into the battery to be injected, the liquid injection port is located outside the shell, and the liquid outlet is located in the battery to be injected. The vacuumizing assembly is arranged on the shell, and the vacuumizing end of the vacuumizing assembly communicates with the cavity. The battery cell opening of the to-be-injected battery is sealed by the shell, the electrolyte is directly injected into the to-be-injected battery by the electrolyte injection pipe, a pressurization process is omitted, and the whole battery cell opening does not need to be exposed to air, so that the injection of the electrolyte can be realized, and the contact amount and the contact area of the air and the electrolyte can be reduced.
Owner:EVE ENERGY CO LTD

Square steel shell structure and battery

The utility model relates to the technical field of lithium ion batteries, and discloses a square steel shell structure and a battery. The square steel shell structure comprises a square shell provided with a battery cell mounting groove and a cover plate used for blocking a notch of the battery cell mounting groove; a plurality of reinforcing columns are fixedly arranged at the groove bottom of the battery cell mounting groove; and one end, far away from the groove bottom of the battery cell mounting groove, of the reinforcing column is fixedly connected with the cover plate. According to the square steel shell battery cell, the fixing columns are additionally arranged in the square shell, and the square shell and the cover plate are fixed, so that the whole battery cell is subjected to segmented reinforcement, the deformation resistance of each part of the square steel shell structure is enhanced, the problem that the square steel shell structure is easy to deform is effectively solved, and the service life of the square steel shell battery cell is prolonged.
Owner:SHENZHEN HIGHPOWER TECH CO LTD

Metamorphic robot with remote central motion mode and Schnflies motion mode

The invention discloses a metamorphic robot with a remote center motion mode and a # imgabs0 motion mode. The metamorphic robot comprises four mechanical arms and a motion module, wherein every two mechanical arms are connected through a rotation pair. The two ends of the first mechanical arm are connected with the second mechanical arm and the third mechanical arm through right-angle connecting pieces correspondingly. The motion module is installed in the fourth mechanical arm and comprises a spline lead screw shaft, a spline nut and a lead screw nut, wherein the spline nut and the lead screw nut are arranged on the spline lead screw shaft and connected with a lead screw pair in a sleeved mode through a spline pair. The end part of the spline lead screw shaft is provided with a flange connecting actuator; the spline and the lead screw nut are driven independently or simultaneously, so that the spline lead screw shaft can output two-degree-of-freedom movement of rotation and movement. Two ends of the fourth mechanical arm are respectively connected with the other ends of the second mechanical arm and the third mechanical arm through revolute pairs, so that the fourth mechanical arm has two-degree-of-freedom one-rotation and one-movement motion relative to the first mechanical arm; and finally, the whole metamorphic robot can realize two different motion modes of three-movement and one-rotation four-degree-of-freedom # imgabs1 # motion and three-rotation and one-movement four-degree-of-freedom remote center motion.
Owner:BEIHANG UNIV

Shared electrolyzer monitoring system and method

The invention relates to a shared electrolyser monitoring system and method. Electrochemical impedance spectroscopy (EIS) systems and methods are described herein that facilitate the distribution of a single excitation generator across a plurality of electrolyzer stacks, each electrolyzer stack including a set of electrochemical cells. By distributing excitation signals, impedance data of the cells in each electrolyzer stack can be measured, e.g., assessed their condition or the condition of the stack, without the need for a separate excitation block for each electrolyzer stack. In various embodiments, a shared excitation generator is achieved by sequentially directing excitation signals to different stacks. A final response signal indicative of the impedance of the cell or the entire cell stack is locally processed on each respective electrolyzer stack. Advantageously, the excitation generator can be remotely positioned, for example, in a location constrained by less strict security measures, thereby reducing equipment and operating costs.
Owner:ANALOG DEVICES INC

Membrane protein imaging technology

The invention belongs to the technical field of biology, and particularly discloses a membrane protein imaging method and application thereof.The method comprises the steps that different DNA molecules are used as response molecules to mark cell membranes and target membrane proteins, then the response molecules marked on the target membrane proteins can trigger molecular dynamic recruitment based on entropy driven circulation through a strand displacement reaction, and the dynamic recruitment is obtained. Causing a large number of probes in the solution to be recruited to the cell membrane; signals are expanded to the whole cell membrane from the membrane interface protein, so that ectopic amplification imaging of the membrane protein based on molecular dynamic collection is realized; in addition, UCNPs are selected to replace a traditional fluorescent part to further enhance the signal, and the method can effectively enhance the imaging signal of the low-abundance target membrane protein; meanwhile, the biological significance and the dynamic regulation and control process of the cell membrane protein can be known more deeply, and the method has great application value in the field of biological medicine.
Owner:SUZHOU CHIEN SHIUNG INST OF TECH

A MIMO-based base station scheduling method, device and storage medium

The present invention discloses a MIMO-based base station scheduling method, device and storage medium, which obtains multiple empty groups by pairing the antenna ports of each user device with empty allocation, and processes the multiple empty groups, specifically determining the priority of the empty group according to the priority of the antenna port in the empty group, and further determining the number of resource blocks required for each empty group. Finally, according to the priority of urgency or throughput, and under the priority sorting of the empty group, the scheduling of each empty group can be completed to allocate the required number of resource blocks. Therefore, the scheduling method of the present invention is extended and optimized on the existing basis, taking into account the fairness between most user devices and the throughput of the entire cell covered by the base station, and flexibly performing adaptive scheduling, which greatly improves the throughput of the cell, so that the base station can use a better way to handle the complex environment of densely populated areas, such as the scheduling problem of a stadium with tens of thousands of people.
Owner:INST OF COMPUTING TECH CHINESE ACAD OF SCI NANJING INST OF MOBILE COMM & COMPUTING INNOVATION

Cylindrical battery structure with positive and negative electrodes on the same side

This invention relates to the field of cylindrical batteries, specifically a cylindrical battery structure with positive and negative electrodes on the same side. It addresses the technical problems of existing cylindrical battery structures that mostly employ structures where positive and negative electrodes are led out from two opposite end faces. This structure forces current to flow through the casing, resulting in increased internal resistance and severe heat generation in the entire cell. Furthermore, in cell structures with tabs on opposite sides, the current collectors for both positive and negative electrodes occupy battery space, reducing the area for chemical coating on the electrodes and thus lowering the overall capacity of the cell. The invention includes a casing, a lower insulating sheet, a cell, a positive current collector, a negative current collector, an upper insulating sheet, and a top cover. The casing is a cylinder open at one end. The cell has a positive electrode tab area, a negative electrode tab area, and a tabless area, all located on the same side of the cell. The upper insulating sheet has an electrolyte immersion port, a central positioning post, and an opening for the current collector.
Owner:YANTAI LIHUA ELECTRIC POWER TECHNOLOGY CO LTD

Alpha-ketoisocaproic acid producing strain as well as construction method and application thereof

PendingCN120005792ABacteriaMicroorganism based processesIsohexanoic acidEntire cell
The invention provides a strain for producing alpha-ketoisocaproic acid as well as a construction method and application thereof. The strain is obtained by taking C.glutamicum Val19 as an initial strain through a gene modification method and comprises the following steps: knocking out an ltbR gene, and introducing a leuB gene at an NcgCgl0021a site; the method comprises the following steps: introducing a leuCD gene at a site NcgCgl0998a to obtain a strain KlC3; the method comprises the following steps: linearizing a pXtuf plasmid by using Hind III and BamH I, replacing a Ptuf promoter with a Ptac promoter, then connecting a euA gene segment with the Ptac promoter, and electrically transferring the obtained pXtuf-euA plasmid into a KIC3 competent state; the constructed strain can produce alpha-ketoisocaproic acid at high yield, exceeds the previous fermentation result and most of the whole cell catalysis process, and highlights the industrial application potential of alpha-ketoisocaproic acid.
Owner:TIANJIN UNIV OF SCI & TECH

Solar photovoltaic module

The present application relates to the technical field of solar photovoltaic module manufacturing, and provides a solar photovoltaic module. The solar photovoltaic module comprises a plurality of cell strings; each cell string comprises a plurality of cell pieces of which edges are sequentially stacked and which are electrically connected; the cell pieces are obtained by cutting an entire cell; and in an extension direction of the cell string, for two adjacent cell pieces, a non-cutting edge of a preceding cell piece is located above a cutting edge of a subsequent cell piece, and the non-cutting edge of the preceding cell piece is located at a light receiving side of the photovoltaic module. The photovoltaic module having a specific structure can effectively improve the power generation efficiency of the photovoltaic module, and also has advantages such as a short research and development period and low research and development costs.
Owner:HUANSHENG NEW ENERGY (JIANGSU) CO LTD

A closed flow cytometry sample processing device

The present invention relates to the field of cell sample storage technology, and in particular to a closed flow cell sample processing device. The device comprises a sealing ring membrane that separates the storage cavity into a first chamber and a second chamber that are not connected to each other, and the sealing ring membrane comprises a sealing body, a first opening blind seam, a second opening blind seam and a guide slot, wherein the second opening blind seam corresponds to the position of the first opening blind seam; the guide slot is used to quickly break the sealing ring membrane and guide the cell sample to be extruded vertically in a jet-like shape after being pressurized. The present invention can break the sealing ring membrane by pressure in a completely closed state, and extrudes the cell sample in a jet-like shape from the discharge head of the storage device in a jet-like shape after being pressurized, and vertically injects it into the sample tube to be mixed. During the entire cell sample adding operation, the cell sample does not come into contact with the external environment, thereby ensuring that the cell sample is not contaminated by the external environment to a great extent, avoiding external contamination, and improving the sterility of the sample processing.
Owner:南昌大学第一附属医院

Integrated circuit standard cell library layout quality verification method and system

The invention discloses a layout quality verification method for an integrated circuit standard cell library, and aims to solve the problems that design errors are exposed during later integration and the design efficiency is reduced due to the fact that only a single standard cell is checked and an actual application scene cannot be simulated in a traditional method. It is ensured that errors are not reported when unit data are read in the layout and wiring stage; through modular random splicing, a layout and wiring environment can be simulated to the greatest extent, and a complete module is generated. A physical unit is inserted, invalid error reporting is avoided, DRC checking of the module is carried out, and layout and wiring are ensured; the units are spliced in a pairwise surrounding manner, so that the ergodicity of the spliced units and the test coverage rate of the spliced surfaces are ensured; through winding property inspection, it is ensured that accidental DRC is not generated due to connection punching when the layout wiring tool is connected to a standard unit.
Owner:PRIMARIUS TECH CO LTD

Vertical insulated gate power switch with isolated base contact regions

In a vertical power device with trenched insulated gates, there is an npnp layered structure. The vertical gates turn on the device with a suitable gate bias to conduct a current between a top electrode and a bottom electrode. In an example, implanted n+ source regions are formed in the top surface within a p-well. Between some gates, the overlying dielectric is opened up, by etching, to expose distributed p-type contact regions for the p-well. The dielectric is also opened up to expose areas of the n+ source regions. The top electrode metal directly contacts the exposed p-type contact regions and the n+ source regions to provide distributed emitter-to-base short across the cellular array to improve device performance in the presence of transients. The p-contact regions are isolated from the n+ source regions, prior to the deposition of the metal electrode, due to the p-type contact regions not abutting the n+ source regions.
Owner:PAKAL TECH LLC

In-memory processing of vector-matrix multiplications by a hardware accelerator using local multimode decompression of matrix weights

The invention is notably directed to a method of processing data at a hardware accelerator device (or "accelerator" for short). The accelerator (1) includes processing means (2) and an in-memory computing (IMC) device (10). The IMC device has a crossbar array structure of cells, which are designed to store weight values. The method comprises the following steps, which are performed at the accelerator. To start with, data encoding decompression parameters and weight values are received at the accelerator. The weight values are assumed to have been compressed according to a multimode compression scheme, whereby the received data include distinct subsets of the weight values that have been compressed according to respective compression modes. Next, the distinct subsets of the weight values are decompressed using said processing means (2), based on respective decompression modes that are selected in accordance with the decompression parameters. The decompression modes correspond to said compression modes. I.e., a given decompression mode can be regarded as the reciprocal of the corresponding compression mode. The decompressed weight values are subsequently stored across the cells. Eventually, vector-matrix multiplications are performed through to the crossbar array structure (10) as multiply-accumulate operations based on the stored weight values. The above solution leads to reduced data transmission and local storage requirements. Compressed data are transmitted more efficiently and more rapidly to the accelerator, something that is notably beneficial to machine learning (ML) applications. Also, the accelerator can locally store more compressed data (all things being otherwise equal), prior to decompressing such data. Interestingly, the received data can be proactively decompressed in situ, while the IMC device performs VMMs based on weight values that are currently active. Furthermore, the VMMs are efficiently performed, in-memory, by the crossbar array structure of the IMC device. The invention is further directed to related accelerator devices and computer program products.
Owner:AXELERA AI BV

Mobile phone shell with replaceable back panel

The utility model discloses a mobile phone shell with a replaceable back panel, belongs to the technical field of mobile phone shells, and mainly solves the problems that in the prior art, a mobile phone shell is of an integrated shell structure, a back plate behind the shell is difficult to disassemble and replace, the whole mobile phone shell needs to be replaced once decoration needs to be replaced due to the single pattern of the mobile phone shell, and the cost is high. The mobile phone shell comprises a mobile phone shell body, a combination groove is formed in the mobile phone shell body in a penetrating mode, a positioning skirt edge is fixedly connected to the interior of the combination groove, an installation back plate is embedded into the combination groove, and a first magnet block is embedded into the front face of the positioning skirt edge; second magnet blocks corresponding to the first magnet blocks are embedded in the back face of the mounting back plate, clamping grooves are formed in the two sides of the mounting back plate, two symmetrical mounting bases are fixedly connected into the combined groove, guide sliding grooves are formed in the mounting bases, movable blocks are slidably mounted in the guide sliding grooves, and limiting clamping blocks are fixedly connected to one ends of the movable blocks.
Owner:SUPERCASE ENTERPRISE CO LTD

GelMA hydrogel micro-fluidic chip and application thereof in cell culture and drug test

The invention relates to a GelMA hydrogel micro-fluidic chip and application of the GelMA hydrogel micro-fluidic chip in cell culture and drug testing. The micro-fluidic chip is made of GelMA hydrogel and specifically comprises a cell culture chamber, and micro-columns arranged in an array are arranged in the cell culture chamber; the drug delivery channel surrounds the periphery of the cell culture chamber; and the gel bionic barrier layer is arranged between the cell culture chamber and the drug delivery channel and is used for inducing the drug in the drug delivery channel to diffuse into the cell culture chamber. The application of the GelMA hydrogel micro-fluidic chip in cell culture and drug testing comprises the following steps: adding a cell solution from a cell solution inlet until the whole cell culture chamber is filled with the cell solution; a to-be-tested medicine solution is added into the medicine conveying channel, and the action effect of the tested medicine on the cells is simulated. Compared with the prior art, the micro-fluidic chip disclosed by the invention has the advantages that the drug can be diffused from the periphery to the internal cell culture chamber, and the micro-fluidic chip can be applied to cell culture and high-throughput drug test.
Owner:SHANGHAI UNIV

Modular flow cytometer and use method thereof

The invention discloses a modular flow cytometer and a use method thereof, and belongs to the technical field of flow cytometers, a cell sorting and collecting module is detached, then a rotating handle is rotated to enable a connecting shaft to drive a worm to rotate, a plurality of push plates drive a plurality of clamping strips to synchronously move and separate from clamping grooves in a bottom groove, and after a shell of the flow cytometer is lifted upwards, the flow cytometer is separated from the bottom groove. Fastening screws on the two sides of the isolation frame are unscrewed so that the isolation frame can be separated from the two sides of the movable supporting module, the isolation frame is lifted so that insertion holes in the isolation frame can be separated from a plurality of limiting columns in the movable supporting module, and the supporting and protecting module and the isolation frame can be detached from the movable supporting module. According to the cytometer disclosed by the utility model, the convenience of transferring and carrying the cytometer is improved, independent carrying or combined carrying is more labor-saving, the consumption of manpower and material resources can be effectively reduced, modules with problems can be pointedly overhauled or replaced, the whole cytometer does not need to be disassembled, and the maintenance difficulty is reduced.
Owner:WUHAN KANGSHENGDA MEDICAL LAB CO LTD

Efficient delivery of cargo across cell membranes using a continuous flow fluidics system

Methods, systems, processes and devices for transcellular membrane delivery are provided herein. In one aspect, a device includes a substrate including a mixing channel, a processing chamber and a dilution channel to perform a process of transporting an effective load across the entire cell membrane. On the other hand, a system includes a reservoir for a cell suspension, a transfer solution reservoir and a stop solution connected to a pump. The system also includes an agitator, a heater, a temperature controller and a controller for operating the system. On the other hand, cells in the suspension are mixed with a transfer solution in a microfluidic mixing chip. The transfer solution contains a permeabilizing agent that causes cell permeabilization, thereby allowing the effective load to be transported from the transfer solution through the cell membrane into the cell.
Owner:AVECTAS

Cell waste liquid collecting device

The utility model discloses a cell waste liquid collecting device, and relates to the technical field of waste liquid collecting equipment. The cell waste liquid collecting device comprises a base, and further comprises a transferring assembly arranged in the middle of the surface of the top of the base and used for transferring a pore plate and adjusting the inclination angle of the pore plate; the suction assembly is arranged on the surface of the top of the base and located on one side of the transfer assembly, and the suction assembly is used for sucking waste liquid on the pore plate; and the supporting assembly is arranged on the surface of the top of the base and located between the transferring assembly and the suction assembly, and the supporting assembly is used for installing the liquid suction end of the suction assembly and adjusting the position of the liquid suction end of the suction assembly. Therefore, the whole cell waste liquid collection efficiency can be improved, and the working intensity is reduced.
Owner:BETTER WAY (SHANGHAI) COSMETICS CO LTD

Space antenna cell skeleton structure, method, system, medium and equipment

A modular space antenna cell skeleton structure with equal rib length and equal gap, a generation method, a system, a medium and an apparatus. In the method, an upper initial skeleton structure of a central cell is generated, where the lines connecting the six vertices of a regular hexagon and the geometric center point form six ribs, which constitute the upper initial skeleton structure of the central cell; skeleton structures of other cells are generated, where the skeleton structures of other cells are generated in units of ribs, and the newly generated ribs are connected to the ribs, so the vertex at one end of the newly generated rib is known, and the two vertices of the newly generated rib serve as key points. The set of key points of all ribs in a single cell serves as the key point of the cell; all ribs and key points are gradually generated along a path from the center to the edge, and all key points are updated to generate gaps between cells; the key points are extended along the direction from the center of the sphere to itself by the distance of a back frame to obtain new key points; and the key points are connected in sequence to obtain the skeleton structure of the entire cell.
Owner:XI AN JIAOTONG UNIV

Method for dynamically packaging microbial cells by using hydrogen bond organic framework material

The invention relates to a method for dynamically encapsulating microbial cells by using a hydrogen bond organic framework material, and belongs to the technical field of cell encapsulation. The method comprises the following steps: preparing nano HOF, dispersing cells in a culture medium, adding a nano HOF aqueous dispersion, culturing, and dynamically packaging proliferative cells by the HOF. According to the invention, a hydrogen bond organic framework material monomer containing carboxyl is selected to encapsulate cells, self-assembly of organic molecule units on the surfaces of the cells is realized through a dynamic hydrogen bond network, and highly reversible hydrogen bonds interact to construct an intelligent encapsulation shell with a controllable disassembly / assembly function; and continuous packaging protection in the whole cell proliferation process can be realized.
Owner:BEIJING INST OF TECH