2results about How to "Achieve infiltration" patented technology

The application belongs to the field of biomedical engineering, and discloses a human live mucosa organoid and a construction method and application thereof. The construction of the organoid comprises the following steps: preparing a cell gel compound, filling the cell gel compound into a support, implanting the support into a nude mouse subcutaneously after gelation, and obtaining the human live mucosa organoid after culturing for 1-3 weeks. The application also discloses the application of the organoid in disease research or drug screening. The application constructs a sustainable in-vivo biomimetic air-mucosa gas-liquid interface, realizes the transition of mucosa from an "ex-vivo static model" to an "in-vivo dynamic live system", and realizes the comprehensive evaluation of the curative effect of anti-infection drugs from three dimensions of pathogenic bacteria elimination, inflammation reaction regulation and immune cell recruitment inhibition in application, thereby breaking through the limitation of traditional models that can only evaluate the in-vitro bacteriostatic activity and being more consistent with the actual effect of clinical drug treatment.

The utility model relates to the technical field of lawn forming facilities, in particular to a lawn ecological floating bed which comprises a frame body, a plurality of layers of non-woven fabrics are detachably connected to the bottom of the frame body, floating bed substrates are laid on the non-woven fabrics, poa pratensis is planted on the floating bed substrates, a filter box is further detachably connected to the lower portion of the frame body, and the filter box is connected with the bottom of the frame body. A through hole is formed in the filter box, a driving pipe is further arranged on the outer side of the frame body, a positioner and a driving module are arranged in the driving pipe, a paddle is arranged at the bottom of the driving pipe, the paddle is rotationally connected with the output end of the driving module, and the driving module is driven through a remote controller. While water body remediation is carried out, agricultural waste resources are effectively utilized for lawn planting, after the lawn is formed, the lawn is rolled into a turf roll to be conveyed and laid, and the win-win situation of water body purification and turf production is achieved.