164 results about "Pharmaceutical Plants" patented technology

A catalyst comprising a plurality of support nanoparticles and a plurality of catalytic nanoparticles. At least one catalytic nanoparticle is bonded to each support nanoparticle. The catalytic particles have a size and a concentration, wherein a first configuration of the size and the concentration of the catalytic nanoparticles enables a first catalysis result and a second configuration of the size and the concentration of the catalytic nanoparticles enables a second catalysis result, with the first and second configurations having a different size or concentration, and the first and second catalysis results being different. In some embodiments, the first catalysis result is a selective reduction of a first selected functional group without reducing one or more other functional groups, and the second catalysis result is a selective reduction of a second selected functional group without reducing one or more other functional groups.

Process for preparing a powder comprising the steps of providing at least one first component in liquid form at ambient temperature, providing at least one second component having a melting point or melting range in the range from above ambient temperature to below the degradation temperature of said first component, forming a homogenous liquid mixture comprising the at least one first component and the at least one second component by stirring and heating the mixture to or keeping the mixture at a temperature in the range from above the melting point or melting range of the second component and below the degradation temperature of the first component, transferring the liquid mixture to at least one spray congealing unit, spray congealing the mixture, and isolating the powder obtained upon spray congealing.

The Spiro compound represented by the following general formula [Ia], its pharmaceutically acceptable salt or a solvate thereof

This invention involves a mushroom cultivation material and production process, it belongs to the field of bio-engineering technology. This mushroom cultivation material contains Chinese crud drug residue 30 ~ 40 share, cotton shells 50 ~ 60 share, urea 1 ~ 2 share, wheat bran 5 ~ 7 share, potassium sulfate 0.5 to 1.5 share, calcium superphosphate 0.5 to 1.2 share, zinc sulfate, magnesium sulfate, borax, ferrous sulfate together for 0.4~1 share, calcined lime 0.5 to1.3 share. Because of using materials containing substances such as Chinese crud drug residue, the produced mushroom cultivation material of this invention has antibacterial effect. Through the implementation of the invention reached so no longer waste residue cause environmental pollution, reduce the factory heavy economic burden caused by the sewage problem.

The use of substituted amides for modulating the activity of 11β-hydroxysteroid dehydro-genase type 1 (11βHSD1) and the use of these compounds as pharmaceutical composi-tions, are described. Also a novel class of substituted amides, their use in therapy, phar-maceutical compositions comprising the compounds, as well as their use in the manufac-ture of medicaments are described. The present compounds are modulators and more specifically inhibitors of the activity of 11βHSD1 and may be useful in the treatment of a range of medical disorders where a decreased intracellular concentration of active gluco-corticoid is desirable.

This invention features a compound of the following formula: T-(-L-C)m, T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C is a non-antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or 8, in which the transportophore has an immune selectivity ratio of at least 2, the transportophore is covalently bonded to the non-antibiotic therapeutic agent via the bond or the linker, and the compound has an immune selectivity ratio of at least 2.

The invention discloses rhodococcus ruber FQ-2 and an application thereof in degradation of acetone and other common industrial organic pollutants. The application method comprises the steps: an inorganic salt culture medium containing acetone and other common industrial pollutants is inoculated with the rhodococcus ruber FQ-2, a degradation reaction is carried out under the conditions of the temperature of 30 DEG C and the rotating speed of 160 r/min, and thus the organic pollutants are degraded; the common organic pollutants comprise acetone, n-hexane, carbon disulfide, chlorobenzene, butylacetate, ethyl acetate or alpha-pinene. The rhodococcus ruber FQ-2 is taken from activated sludge of an aeration tank of a pharmaceutical factory in Zhejiang province, has good degradation effect on VOCs organic pollutants, especially acetone, and can completely convert acetone into harmless substances such as CO2, H2O, cell biomass and the like; at the same time, the bacterial strain also can degrade common industrial pollutants such as carbon disulfide and chlorobenzene in different extent, so the bacterial strain has broad application prospects in biological purification of industrial wastegas and wastewater.

Provided is an ORL-1 receptor agonist having improved bioavailability based on superior metabolic stability and strong and high selectivity, as compared to conventional compounds. A compound represented by the formula (I) wherein each symbol is as defined in the claims.

The invention provides a package for storing medical devices that substantially eliminates reaction of a pharmaceutical agent, antimicrobial agent or both with light, which agent is incorporated into the device or contained in a solution in which the device is packaged.

A method of coating a pharmaceutical substrate includes the steps of applying an active coating material to a surface of the substrate to form an active coating layer and applying a cover coating material onto the active coating layer to form a cover coating layer. The active coating layer is substantially completely covered by the cover coating layer.

The scheme relates to a processing device of a pharmaceutical plant, namely pueraria, and in particular relates to a pueraria powder processing device; the pueraria powder processing device comprises an impact tank for containing pueraria and an impact hammer arranged in the impact tank; the other end of a hammer handle of the impact hammer passes through a locating plate; a stop block is fixed on the other end of the hammer handle of the impact hammer; a vertical circular ring is arranged in the centre of the hammer handle; a pressure spring is arranged between the circular ring and the locating plate; a cam connected to a motor is arranged in the centre of the circular ring; a smooth bump is arranged on the inner wall of the circular ring in the second quadrant; the bump is gradually increased along the clockwise direction; two opposite ejection blocks are arranged on the outer edge of the cam; the distance between the outer edges of the ejection blocks and the rotation centre is gradually increased along the anticlockwise direction of the cam; and the distribution angle of single ejection block is 90 DEG C. The pueraria powder processing device in the technical scheme provided by the invention is capable of effectively impacting pueraria, so that slurry in pueraria can be separated from pueraria better.

A method is disclosed for removing impurities from an elastomer intended for medical or pharmaceutical use, which includes a step of performing a first solvent extraction process on the elastomer by contacting the elastomer with a first extracting solvent in a non-supercritical state to substantially remove impurities from the elastomer, thereby leaving a residue of said first extracting solvent in the elastomer. The elastomer is there after subjected to a second solvent extraction process, by contacting the elastomer with a second extracting solvent, which is a supercritical fluid or a mixture of super critical fluids, in order to remove substantially reduce the concentration of the residue of the first extracting solvent remaining in the elastomer after the first solvent extraction process.

The invention relates to metal fullerols and its application in preparing inhibition tumor medicine. Its general formula is M@C2m(OH)x, which M can be Gd, La, etc, m=41 or 30, x is not less than 10 and less than 50; it also can be M@C2mOxHy. Compared with clinic common using cyclophosphamide, cisplatin, paclitaxel etc, the metal fullerols M@C2m(OH)x or M@C2mOxHy has the advantages of little use level, low toxicity, high tumor inhibition ratio.

The invention discloses novel triazoles compounds, whose chemical names are 3-(substituted phenyl)-1-(2,4-difluorophenyl)-2-(1,2,4-triazol-1-yl)-2-propen-1-one, 1-[3-(substituted phenyl)-1-(2,4-difluorophenyl)-2-(1,2,4-triazol-1-yl)allyl]piperidinium, 3-(substituted phenyl)-1-(2,4-difluorophenyl)-2-(1,2,4-triazol-1-yl)-2-propen-1-ol, and 1-[3-(substituted phenyl)-1-(2,4-difluoropheny)-2-(1,2,4-triazol-1-yl)proyl]piperidinium, with antimicrobial activity; further discloses the preparation method and pharmaceutical use thereof.

A biomedical and pharmaceutical waste sterilization system includes a vessel comprising a treatment chamber, wherein the vessel is disposed in an open frame for support thereof and the vessel comprises an opening on a top side configured to receive biomedical waste and a shredding system to treat the biomedical waste; and a chemical loading system configured to receive liquid ozone for introduction into the treatment chamber prior to and during a treatment cycle for the biomedical waste.

The invention discloses a biological straw fertilizer, and a production method and application thereof, and belongs to the field of fertilizer. The biological straw fertilizer contains the following components: nitrogen, phosphorus and potassium (N + P2O5 + K2O); straw organic matters; and biological synergist. A single nutrient content of the nitrogen, phosphorus, potassium and straw organic is not less than 1.6-2.5%; and the biological synergist is prepared by biological fermentation on soybean straw, mung bean straw, pea straw, millet straw, barley straw, rape straw, peanut straw, capsicum rod, tomato rod and drug residue from industrial scale pharmaceutical factory. The biological straw fertilizer protected by the present invention combines effects of microbial fertilizer, and organic and inorganic fertilizer, and can protect the ecological environment. From farm to table, standard safe production of grain can be executed. Therefore, the biological straw fertilizer is a non-toxic, harmless, green and environment-friendly fertilizer.

The invention provides a method for preparing hepatitis-resisting active sites mainly from medicinal herbal Swertiamarin, which comprises: (1) disintegrating and extracting in water or water hydrophilic organic solvent through backflow, filtering to obtain merged concentration liquid, freezing, centrifugally filtrating, obtaining extract, (2) passing through macroscopic adsorption resin columns, (3) water scrubbing the resin columns, purging with 10-70% ethanol or methanol, collecting the eluent and concentrating.

PEO-PPO-PEO polymers and vinyl monomers are used to prepare several block copolymers via consecutive atom transfer radical polymerization (ATRP). The block copolymers provide good delivery characteristics and can be used as a gene/drug delivery carrier for therapy and diagnosis.

A tablet (4) for pharmaceutical use has on at least one part of its surface a diffractive microstructure (11) which generates diffraction effects which can be perceived in the visible spectral range and which serve as visual safety feature. The tablet (4) consists of a plurality of individual powder particles, where the diffractive microstructures (11) are impressed into the surface of the individual powder particles. A compression tool (1, 1a, 1b, 3) to produce such tablets (4) has on one pressing surface of the compression tool (1, 1a, 1b, 3) micro-structures (11), where said microstructures (11) have dimensions which are smaller than the dimensions of the individual crystallites (30) of the material of the pressing surface of the compression tool (1, 1a, 1b, 3). The micro-structures (11) of the compression tool can be produced for example by ion etching or by imprinting.

The invention provides a siRNA (small-interference ribonucleic acid) which has the following sequences: a sense strand of 5'-GGAAACUACUGUUGUUAGAdTdT-3' and an antisense strand of 5'-UCUAACAACAGUAGUUUCCdTdT-3'; and the siRNA has modification from one of the modes shown in E1 to E8. The invention also provides a medicine composition for preventing and/or treating hepatitis B, which contains the siRNA provided in the invention as active constituents. The invention also provides an application of the siRNA in preparing medicaments for preventing and/or treating the hepatitis B. With specific modification, the purpose of increasing the serum stability of the siRNA can be achieved by only introducing a little modification so that the modified siRNA potential cytotoxicity and influences on biological activity are reduced.

The present invention provides a compound represented by the formula

wherein R¹ is a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or a heterocyclic group optionally having substituent(s), R² is a hydrogen atom or a hydrocarbon group optionally having substituent(s), R³ is a hydrogen atom, a halogen atom, a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or mercapto optionally having a substituent, Xa, Xb, Xc and Xd are each a carbon atom or a nitrogen atom, provided that any one or two of Xa, Xb, Xc and Xd is/are nitrogen atom(s), m is 0 to 2, and rings A to C are each a ring optionally having substituent(s), or a salt thereof, which is useful as an agent for the prophylaxis or treatment of a disease relating to an action of melatonin, and the like.

The invention discloses a method for preparing organic fertilizer for tea by fermentation of solid wastes of traditional Chinese medicine residues and the like. The method comprises the following steps of uniformly mixing traditional Chinese medicine residue sections, fermenting bacteria, traditional Chinese medicine residues, vinasse, crop straws or livestock and poultry manure, preparing compostraw materials with certain ratios of C/N (carbon/nitrogen) and C/P (carbon/phosphor), and fermenting twice, so as to obtain the organic fertilizer for the tea. The prepared organic fertilizer for thetea has the characteristics that the fertilizer effect is stable, humus and various nutritional elements are rich, and the pollution is avoided; the quality of the tea is improved. The preparation method of the special fertilizer for the tea is an innovative project with small investment, short cycle, quick effect, and circulating and sustainable features; the technical resources of reutilized wastes are provided for pharmaceutical factories, wine factories, farmers, livestock farms and the like; the development space is broad, and the market prospect is good.

The present invention is asafetida extract and its pharmaceutical use, and aims at eliminating offensive odor of asafetida and providing one new use. The asafetida extract contains alpha-terpinene, 2-borneol, terpine tetraol, D-fenchol, pinocarveol, etc. and is extracted via conventional process. The asafetida extract is used in preparing drug addiction stopping medicine, and the medicine may be injection, capsule, tablet or granule.