This invention discloses a purification method for isopropanol, a
reagent for spectroscopic analysis. The method includes: S1 mixing industrial-grade isopropanol with an
alkali metal compound, adjusting the pH to 7.0–8.0, and obtaining a neutralized filtrate through
solid-liquid separation; S2 continuously adsorbing and removing impurities from the neutralized filtrate by passing it sequentially through a
molecular sieve adsorption unit, a modified
activated carbon adsorption unit, and a γ-
alumina adsorption unit; S3 subjecting the adsorbed liquid to staged total
reflux distillation, controlling the
reflux ratio at 5–15:1 and the total
reflux time at 1–3 hours, and collecting the top product; S4 filling and sealing the top product under
inert gas protection. This invention achieves closed-
loop control of the entire process by setting online
conductivity and
moisture sensors,
infrared detection devices, and online concentration sensors at key nodes. This method has the advantages of high purity, low
energy consumption, high
recovery rate, and process
controllability, and is suitable for the industrial production of high-purity isopropanol for spectroscopic analysis.