The invention discloses an isosteviol
crystal form I as well as a preparation method and application thereof, the isosteviol
crystal with the
crystal form I has obvious characteristic
diffraction peaks at least at positions of 9.98, 13.54, 15.88, 16.60, 17.26, 18.56, 19.30, 20.76 and 26.04 of 2 theta angles (+ / -0.02) expressed by degrees through X-
ray powder diffraction analysis measured by a Cu-
K alpha ray, and the isosteviol crystal with the crystal form I has the characteristic
diffraction peaks at least at positions of 9.98, 13.54, 15.88, 16.60, 17.26, 18.56, 19.30, 20.76 and 26.04 of the 2 theta angles (+ / -0.02) expressed by degrees. The crystal is characterized by chemical analysis means such as X-
ray powder diffraction analysis (XRD),
thermogravimetric analysis (TG), a polarizing
microscope and
infrared spectroscopy (IR), the crystal has the advantages of high
crystallinity, high stability, high biological
accessibility and the like, the
crystal structure of the crystal is still kept stable after the crystal is placed at normal temperature for 12 months, and the crystal has a good application prospect. The method is suitable for wider application fields.