The invention discloses a radio frequency feed-forward amplifier and a loop self-adaptive control method. The radio frequency feed-forward amplifier comprises a carrier compensation loop, an inter-modulation compensation loop and a chip controller, wherein the carrier compensation loop comprises an amplitude modulator, a phase modulator, a first gain equalizer, a main power amplifier, a delay line and a combiner; the inter-modulation compensation loop comprises a phase regulating circuit, a gain regulating circuit, a second gain equalizer, an error power amplifier, a delay filter and a receiver; the chip controller is used for monitoring the feedback power of the carrier compensation loop and the inter-modulation compensation loop, and self-adaptively regulating the amplitude, phase position and pilot frequency of a corresponding loop. According to the radio frequency feed-forward amplifier and the loop self-adaptive control method, the chip controller is used for monitoring and controlling the two loops, so that the radio frequency feed-forward amplifier is enabled to obtain the optimal compensation effect, rate of convergence and dynamic stability, and the features such as linearity, bandwidth and mode mixing are enabled to be better.