The invention discloses a joint noise reduction method based on variational mode decomposition and permutation entropy, and belongs to the technical field of signal processing. The joint noise reduction method comprises the following steps: firstly, reading a noisy signal x (t); calculating the scale index a value of x (t), and determining the decomposition number K of variational mode decomposition (VMD) according to the a value; secondly, performing K-layer VMD decomposition on the noisy signal x (t) to obtain a series of variational mode components uk; then, calculating the permutation entropy of each variational mode component uk, and further determining the value of K; and finally, removing the noise uk component, and reconstructing the remaining uk component to obtain a noise-reducedand filtered signal. The method has the advantages of adaptively determining the decomposition number, effectively removing noise components and being high in robustness and real-time performance, effective noise reduction and filtering processing can be carried out on signals, and the method has good technical value and application prospects for non-stationary signal noise reduction methods.