The invention discloses a multifunctional surgical square box. The surgical square box includes a box cover, a box bottom and an operating table frame, wherein the box cover and the box bottom are buckled together; the operating table frame is positioned on the box bottom and is positioned in the box cover; an operating table, a life air and electricity support area, an anesthesia machine, a negative pressure aspirator, an electric knife, a surgical washing machine, a dirt collection box, a monitor, a shadowless lamp, a UPS (Uninterrupted Power Supply), an infusion and injection pump set and one or more of air bottles are positioned on the operating table frame. According to the invention, all relevant medical instruments in an operation are integrated; the arrangement positions of the device are integrated according to requirements of clinical medicine; the design is more reasonable design; and at the same time, the surgical square box has the advantages of small size, complete device function, firm and reliable installation, easiness in transportation, convenience in unfolding for use and putting away and the like, can be put into use quickly, and can better meet the requirements of a field first-aid surgery.