120 results about "Quadrupole mass analyzer" patented technology

A mass spectrometer is configured with individual multipole ion guides, configured in an assembly in alignment along a common centerline wherein at least a portion of at least one multipole ion guide mounted in the assembly resides in a vacuum region with higher background pressure, and the other portion resides in a vacuum region with lower background pressure. Said multipole ion guides are operated in mass to charge selection and ion fragmentation modes, in either a high or low pressure region, said region being selected according to the optimum pressure or pressure gradient for the function performed. The diameter, lengths and applied frequencies and phases on these contiguous ion guides may be the same or may differ. A variety of MS and MS/MSⁿ analysis functions can be achieved using a series of contiguous multipole ion guides operating in either higher background vacuum pressures, or along pressure gradients in the region where the pressure drops from high to low pressure, or in low pressure regions. Individual sets of RF, +/−DC and resonant frequency waveform voltage supplies provide potentials to the rods of each multipole ion guide allowing the operation of ion transmission, ion trapping, mass to charge selection and ion fragmentation functions independently in each ion guide. The presence of background pressure maintained sufficiently high to cause ion to neutral gas collisions along a portion of each multiple ion guide linear assembly allows the conducting of Collisional Induced Dissociation (CID) fragmentation of ions by axially accelerating ions from one multipole ion guide into an adjacent ion guide. Alternatively ions can be fragmented in one or more multipole ion guides using resonant frequency excitation CID. A multiple multipole ion guide assembly can be configured as the primary mass analyzer in single or triple quadrupole mass analyzers with or without mass selective axial ejection. Alternatively, the multiple multipole ion guide linear assembly can be configured as part of a hybrid Time-Of-Flight, Magnetic Sector, Ion Trap or Fourier Transform mass analyzer.

A multipole ion guide is configured to improve the transmission efficiency of ions which traverse the length of one ion guide and enter either another multipole ion guide such as a quadrupole mass analyzer or a three dimensional ion trap. The ion transfer multipole ion guide radial dimensions are reduced such that the pole assembly and an appropriately shaped exit lens can be positioned within a portion of the internal space defined by the larger radius second multipole ion guide poles. Ions exiting the first ion guide of reduced size find themselves inside the second ion guide close to the centerline. In this manner ions can be efficiently transferred from one ion guide to another, even for those ions with low kinetic energies. In a second embodiment of the invention, the exit region of a multipole ion guide is configured such that the multipole ion guide poles can be extended into a counterbore of a three dimensional ion trap end cap electrode. With this configuration, ions (including those with low kinetic energies) can be transferred into a three dimensional ion trap with increased trapping efficiency.

Disclosed is a quadrupole mass spectrometer, which is capable of, during an SIM measurement, maximally reducing a settling time-period necessary for an operation of changing an input voltage to a quadrupole mass filter in a staircase pattern, and preventing unwanted ions from excessively entering a detector during a course of changing between a plurality of mass values. Under a condition that a response speed of a DC voltage U to be applied to quadrupole electrodes is less than that of an amplitude of a high-frequency voltage V, a control section 10 is operable to rearrange the mass values in descending order of mass value, and an optimal settling-time calculation sub-section 101 is operable to determine a settling time-period for each of the mass values, based on a mass-value difference and a post-change mass value.

Applicant's present invention comprises mass spectrometer systems that operate in a mass range from 1 to 10¹⁶ DA. The mass spectrometer system comprising an inlet system comprising an aerodynamic lens system, a reverse jet being a gas flux generated in an annulus moving in a reverse direction and a multipole ion guide; a digital ion trap; and a thermal vaporization/ionization detector system. Applicant's present invention further comprises a quadrupole mass spectrometer system comprising an inlet system having a quadrupole mass filter and a thermal vaporization/ionization detector system. Applicant's present invention further comprises an inlet system for use with a mass spectrometer system, a method for slowing energetic particles using an inlet system. Applicant's present invention also comprises a detector device and a method for detecting high mass charged particles.

An apparatus for electronically controlling a quadrupole in a mass spectrometer, comprises radio frequency (RF) drive circuitry and direct current (DC) drive circuitry coupled to a quadrupole, an RF control loop associated with the RF drive circuitry, a DC control loop associated with the DC drive circuitry, and control loop circuitry associated with the DC control loop, the control loop circuitry configured to alter a response of the DC control loop during a settling time period of a step response such that ion transmission through the quadrupole is greater during the settling time than if the response of the DC control loop during the settling time is unaltered.

The apparatus introduces a second adjustable resonant point in a QMS at a frequency that is close to a multiple of the fundamental frequency by adjusting driving point impedance characteristics of the QMS. The apparatus measures the first and second resonant point of the QMS to account for changes in the operational characteristics of the QMS.

The invention relates to a multiphase catalytic reaction device for testing in situ solid-state nuclear magnetic resonance, which is a magic angle spinning multiphase catalytic reactor in which an online solid-state nuclear magnetic resonance system, a quadrupole mass-spectrometer, a gas chromatograph and a laser-induced hyperpolarized 129Xe isotope probe are linked for use. The reactor can apply various solid-state nuclear magnetic resonance techniques to track and detect a catalyst structure, reaction intermediates and species with catalyst activity in the catalytic reaction process; reaction products are qualitatively and quantitatively analyzed by the quadrupole mass-spectrometer and the gas chromatograph, so that the performance of the catalyst is evaluated; simultaneously, laser-induced hyperpolarized 129Xe isotope is used as a probe molecule to study the change of the catalyst structure, adsorption positions and diffusion behaviors of various species in the reaction process and the like. In-situ tracking in the catalytic reaction process and the mechanism of the catalytic reaction can be systematically studied through the various techniques.

A mass spectrometry quantitation technique enables high-throughput quantitation of small molecules using a laser-desorption (e.g., MALDI) ion source coupled to a triple-quadrupole mass analyzer. The ions generated from the ion source are collisionally damped/cooled, and then quantitatively analyzed using the triple-quadrupole analyzer operated in the multiple-reaction-monitoring (MRM) mode. Significantly improved measurement sensitivity is obtained by applying laser pulses to the ion source at a high pulse rate of about 500 Hz or higher. This allows the data acquisition to be performed rapidly, and the speed of about one second for each sample point on the ion source target has been achieved.

In a scan measurement in which a mass scan is repeated across a predetermined mass range, when a voltage is returned from a termination voltage of one scan to an initiation voltage for the next scan, an undershoot or other drawbacks occur to destabilize the voltage value. Therefore, an appropriate waiting time is required. Conventionally, this waiting time has been set to be constant regardless of the analysis conditions. On the other hand, in the quadrupole mass spectrometer according to the present invention, the mass difference ΔM between the scan termination mass and the scan initiation mass is computed based on the specified mass range, and a different settling time is set in accordance with this mass difference. When the mass difference ΔM is small and hence requires only a short voltage stabilization time, a relatively short settling time is set. This shortens the cycle period of the mass scan, which increases the temporal resolution.

In a quadrupole mass spectrometer which measures partial pressure strength according to a gas type in a vacuum system from ion current intensity, a quadrupole mass spectrometer with a total pressure measurement electrode has a total pressure measurement electrode for examining an ion density disposed in a demarcation space which is comprised of a grid electrode and an ion focusing electrode. And, a vacuum system is provided with only the quadrupole mass spectrometer which measures partial pressure strength according to a gas type in the vacuum system from an ion current intensity and does not have an ionization vacuum gauge other than the quadrupole mass spectrometer.

The utility model relates to a quadrangular frustum shaped four-stage mass analyzer with stepped electrodes, comprising four electrodes. The four electrodes can form a space zone, the electrode shape is trapezoid, and the stepped protruding ridge is arranged on the trapezoid electrodes. Two of the four electrodes can form a quadrangular frustum space zone along a bevel edge of the trapezoid respectively. The utility model has the advantages of simple structure and low production difficulty, low production and service costs of the quadrapole spectrometer and wide application.

Provided are a leakage inspection apparatus and a leakage inspection method for inspecting the flow rate of leakage from a tested body disposed in a tested-body chamber 21. The leakage inspection apparatus includes liquid supplying and pressurizing means 11 for supplying a probe liquid to the inside of the tested-body chamber 21 and pressurizing the probe liquid to a high pressure 0.1 MPa or more, vacuum evacuation means 22-b, 23-b and a quadrupole mass spectrometer 34. The tested body 21 is evacuated, the probe liquid is supplied to the inside of the tested body and pressurized to 0.1 MPa or more and the concentration of a probe medium leaked from the tested body and evaporated in a vacuum is measured by the quadrupole mass spectrometer 34, thereby measuring the flow rate of leakage from the tested body. This makes it possible to determine the flow rate of leakage using a liquid as a probe medium and simultaneously possible to perform a pressure tightness inspection at an atmospheric pressure of 0.1 MPa or more, especially at a high pressure ranging from 1 MPa to 1 GPa.

A method for linearizing the sensitivity of a quadrupole mass spectrometric system to allow the sensor to more accurately report partial pressures of a gas in high pressure areas in which the reported data is effected by a number of loss mechanisms. According to the invention, correction factors can be applied empirically or software in a quadrupole mass analyzer system can be equipped with correcting software to expand the useful range of the mass spectrometer.

The invention discloses a material partial pressure gas-release rate test device and method. The device comprises a measuring chamber, a vacuum pump set and a current limiting small hole. The vacuum pump set is connected to the measuring chamber by a gate valve. The front end of the current limiting small hole is connected to the measuring chamber by an angle valve and the rear end of the current limiting small hole is directly connected to the vacuum pump set. Through a quadrupole mass spectrometer and an extractor gauge, base partial pressure values and base nitrogen equivalent total pressure values of different types of gas in the empty measuring chamber and the measuring chamber with a sample are measured so that a sample nitrogen equivalent partial pressure gas-release rate is measured. Only through one quadrupole mass spectrometer, real-time and continuous measurement of a material partial pressure gas-release rate is realized, gas secondary adsorption caused by pressure increasing produced by gas release of a vacuum material in the measuring chamber is reduced and lateral comparison of gas with different components is convenient.

The invention aims to provide a method for testing hydrogen diffusivity or permeability in metal with higher accuracy, and a specific device therefor. The invention is characterized in that the device consists of a sample chamber, an evacuating system, a double-sphere-shaped vacuum chamber, a quadrupole mass-spectrometer, a hydrogen standard leak, a pressure testing system, a vacuum testing system and pipes, wherein both ends of the sample chamber are connected with the evacuating system through the pipes; one end of the sample chamber is connected with a hydrogen source; the pressure testing system is arranged between the sample chamber and the hydrogen source; the upper spherical vacuum chamber of the double-sphere-shaped vacuum chamber is respectively connected with the other end of the sample chamber, the hydrogen standard lead and the quadrupole mass-spectrometer; the lower spherical vacuum chamber of the double-sphere-shaped vacuum chamber is connected with the evacuating system.

The invention discloses a low-temperature enrichment and concentration online high-sensitivity quadripole mass spectroscopy analysis system which comprises a vacuum pump unit, a sample chamber, an analysis chamber, a quadripole mass spectroscopy, a first valve, a second valve and a low-temperature concentrator. The sample chamber, the first valve, the low-temperature concentrator, the analysis chamber, the second valve and the vacuum pump unit are connected in sequence. The analysis chamber is further connected with the quadripole mass spectroscopy. The vacuum pump unit provides needed vacuum degree for the quadripole mass spectroscopy, then, sample gas in the sample chamber is introduced into the analysis chamber through the low-temperature concentrator and analyzed by the quadripole mass spectroscopy. According to the low-temperature enrichment and concentration online high-sensitivity quadripole mass spectroscopy analysis system, the analysis sensitivity of the quadripole mass spectroscopy for trace impurity gas, particularly organic impurity gas is remarkably improved in the vacuum environment.

The present invention relates to a quadrupole mass analyzer which is a core equipment of a majority of mass analyzer, particularly to a quadrupole mass analyzer with a hyperbolic surface made of quartz which is capable of enhancing resolving power and analytical performance of a mass analyzer. The quadrupole mass analyzer according to the present invention includes four quartz tubes separated by predetermined distance to form a shape of rotation symmetry and being parallel to each other; an electric part formed with a predetermined area by a platinum membrane being divided into a prefilter electrode part and a main filter electrode part in a longitudinal direction of the quartz tube in a circumferential surface in an axial direction of the rotation symmetry of the quartz tube, a cross-section of the platinum membrane on an opposing quartz tube forming a substantial hyperbolic surface; a quartz pin being chamfered at both ends in a shape with a same radius curvature as the quartz tube and being closely fixed between the adjacent quartz tubes; and an electrically conductive connection member electrically connecting each of prefilter electrode parts and main filter parts of the opposing quartz tubes so as to apply RF and DC electric source.

The invention discloses a method for determining the content of tin in a tin ore by alkali melting-inductively coupled plasma mass spectrometry. The method comprises the steps: melting and decomposinga sample by sodium oxide, leaching by hot water, acidifying by hydrochloric acid, transferring the solution into a volumetric flask, and separately taking a clarifying liquid; diluting by nitric acid, allowing the sample to enter radio frequency plasma through a sample injection system, and carrying out evaporation, dissociation, atomization and ionization in a high temperature rectangular tube;separating ions by a double-cone interface, an ion mirror and a quadrupole mass analyzer according to the mass/charge size; and finally, detecting by an ion detector, quantitatively analyzing the content of tin by a calibration curve method, and thus quickly, accurately and effectively determining the content of tin in the tin ore. At the same time, the method improves the work efficiency, reducesthe labor intensity of operators, does not cause harm to bodies of the operators, and also has significant social benefits.

The invention discloses a double-ion-source quadrupole mass spectrometer based on single-photon ionization and electron bombardment ionization, and particularly relates to a quadrupole mass spectrometer which can flexibly switch ionization modes according to physical and chemical properties of an analyzed sample. The quadrupole mass spectrometer comprises the components of a single-photon ionization source, an electron bombardment ionization source, an ionization transmission region chamber, a quadrupole mass analyzer chamber, a focusing lens set A, a focusing lens set B, a differential interface pole plate, a differential interface small hole, a sample inlet capillary A, a sample inlet capillary B, a quadrupole mass analyzer, a detector, a side suction valve, a vacuum pump A and a vacuum pump B.