21 results about "Quadrupole mass analyzer" patented technology

The invention discloses a wide-temperature-range ultrahigh vacuum system gas component testing device and method, the device comprises an inner vacuum cavity, an outer vacuum cavity, a sample supporting plate, a quadrupole mass spectrometer, a vacuum system, a vacuum coupling sample transfer rod and a control device, the outer vacuum cavity is used for loading, unloading and transferring a sample, and the inner vacuum cavity is used for maintaining and testing the ultrahigh vacuum system. The vacuum system adopts a mechanical pump, a molecular pump, an ion pump and other multi-stage vacuum pumps to vacuumize, and adopts multiple groups of vacuum gauges to measure different vacuum degrees. A quadrupole mass spectrometer is adopted to analyze and detect gas components generated by the parts.

The invention relates to the technical field of mass spectrometers, and discloses an analytical instrument based on glow discharge and quadrupole mass spectrometry combination, which comprises an ion source, an ion transmission system and an ion separator, wherein the ion source is a glow discharge ion source; the ion separator is a quadrupole rod mass analyzer, and the quadrupole rod mass analyzer comprises four electrodes which are arranged in parallel. Compared with an existing analytical instrument, the glow discharge ion source can directly analyze a solid sample without being pretreated into a solution, and compared with an inductively coupled plasma source, the glow discharge ion source is small in matrix effect and especially suitable for high-salt and high-carbon samples; the quadrupole rod mass analyzer is simple in structure, small in size, low in cost, especially suitable for commercialized popularization and high in scanning speed.

The application discloses a high-inert electrostatic dissipation type collision cell device and a mass spectrometer system thereof, comprising a collision cell device, one end of the collision cell device is connected with a first quadrupole mass analyzer, the other end of the collision cell device is connected with a third quadrupole mass analyzer, and a metal flange is assembled at the positions where the collision cell device is connected with the first quadrupole mass analyzer and the third quadrupole mass analyzer.The high-inert electrostatic dissipation type collision cell device and the mass spectrometer system thereof increase a gas path precise regulation and control module, the module can accurately adjust the gas inlet flow, pressure and gas inlet rate of the collision gas according to the type and ion property of the detected sample, cooperates with a gas flow guide structure in the gas chamber shell, realizes uniform distribution of the collision gas in the gas chamber, supports dynamic switching and precise proportioning of the collision gas at the same time, adapts to different collision dissociation requirements, and improves the universality and detection flexibility of the device.

A shield member for a mass sensor includes a body including an outer shield surface and an inner shield surface defining shield sides and a body portion that is positioned between the shield sides. The shield member further includes a support member configured to support at least a portion of the body and structured to enable airflow though the support member. The body of the shield member is configured to shield one or more components of a mass sensor from a magnetic field.

In various aspects, the methods and systems disclosed herein are capable of operating a Fourier transform mass spectrometer (FTMS) quadrupole mass analyzer in two modes of operation: transmission mode and trapped mode. In trapped mode, ions are first trapped and cooled within the FTMS mass analyzer, then subjected to an excitation pulse and ejected from the FTMS mass analyzer for detection. However, in transmission mode, the FTMS mass analyzer can provide faster analysis because the excitation pulse is applied to ions of a beam of ions that are continuously transmitted through the FTMS mass analyzer.

The invention belongs to the technical field of mass spectrometry, and particularly relates to an on-line soil detection quadrupole mass spectrometer based on an element analysis technology and an analysis method. The sampling system comprises an automatic sampling mechanical arm moving device, a washing device, a blowing device, a sample cabin, a sealing O ring, a sample transmission mechanism, a laser and a primary reflecting plate, and the analysis system comprises a laser reflecting lens, a transmission lens, an ion source, a mass analyzer, a detector, a vacuum transfer cavity, a vacuum analysis cavity, a mechanical pump, a molecular pump and a control computer. A mass analyzer, an ion source and a transmission lens are arranged in a cavity body of the vacuum transfer cavity, the molecular pump is connected with the vacuum transfer cavity, and the vacuum transfer cavity and the analysis vacuum cavity are two-stage differential systems. Laser and ion source double ionization is adopted to improve the ion yield, interference is reduced in combination with a two-stage differential vacuum system, and the quadrupole mass spectrometer is high in vibration tolerance and suitable for field complex environments such as unmanned farms.

The invention provides a control circuit and a control method of an electron ionization source and a quadrupole mass spectrometer. The control circuit comprises a first filament heating circuit, a second filament heating circuit, a detection circuit and a logic circuit. The logic circuit is electrically connected with the detection circuit, the first filament heating circuit and the second filament heating circuit, and controls the first filament heating circuit and the second filament heating circuit according to the detected current. According to the invention, the filament is directly protected in the control circuit according to the size of the ion current, so that the response delay is minimized. And multiple-level improvement of the sensitivity of the ion source can be realized. In a conventional mode, a user can select the double filaments to work alternately, and the maintenance frequency of the ion source is not affected.

A method for multiple transition monitoring of at least one analyte in a sample using a quadrupole mass analyzer (110) is disclosed. The method comprises the following steps: a) at least one voltage application step (112), wherein in the voltage application step a direct current (DC) voltage and a radio frequency (AC) voltage are applied between two pairs of electrodes (114) of at least one mass filter (116) of the quadrupole mass analyzer (110), wherein the AC voltage has an amplitude V AC , and the DC voltage has an applicable voltage V DC , wherein a supplementary AC voltage is superimposed on the AC voltage and the DC voltage, wherein the amplitude AV DC of the supplementary AC voltage is V DC,最大 , wherein V DC,最大 is the maximum voltage output of the DC voltage and b is the bit size of at least one electronic board (118) of the mass filter (116) of the quadrupole mass analyzer (110); b) at least one measurement step (122), wherein at least one transition of the analyte is determined with at least one detector (120) of the quadrupole mass analyzer (110).

This application relates to the field of quadrupole mass analyzer technology and provides an assembly fixture for a quadrupole mass analyzer, including: a base, a first clamping fixture, a second clamping fixture, a third clamping fixture, a rectangular positioning component, and a cross-shaped equally spaced positioning component. This assembly fixture for the quadrupole mass analyzer can improve the assembly accuracy of the quadrupole mass analyzer, reduce the requirements for assembly personnel, and improve the production efficiency of the quadrupole mass analyzer. The cross-shaped equally spaced positioning component and the rectangular positioning component can define the relative positions between the four poles, and the first, second, and third clamping fixtures can fix the positions of the four poles and the ceramic base, making the assembly process more stable and achieving high-efficiency and high-precision assembly of the quadrupole mass analyzer.

The invention discloses a multi-path residual gas analysis and collaborative detection system based on a single ion source. The multi-path residual gas analysis and collaborative detection system mainly comprises an ion source assembly, a quadrupole rod mass analyzer, a detection system and a control and data fusion module, the ion source assembly comprises a filament module and two transmission lenses, residual gas is ionized into ions by the filament module, the ions flow into the quadrupole rod mass analyzer through the transmission lenses and are screened, and ions with specific mass flow into the detection system from the quadrupole rod mass analyzer and are converted into digital signals to be transmitted to the control and data fusion module; the control and data fusion module fuses digital signals of the two detection systems into a single spectrogram. According to the invention, through a combined RGA design, comprehensive application and linkage of multiple process scenes are realized; simultaneous scanning in positive and negative ion modes can be realized, and acquired data information is richer; when full-spectrum information is scanned, sectional scanning can be realized, and the scanning speed is at least doubled.

The invention discloses a quadrupole mass spectrometer capable of inhibiting interference of high-abundance ions on a low mass end. The quadrupole mass spectrometer comprises an ion source, a quadrupole mass analyzer, a first power supply device, a second power supply device and a third power supply device, wherein the ion source comprises an ionization chamber and a filament assembly arranged at an electron inlet of the ionization chamber; the quadrupole rod mass analyzer is arranged at the downstream of the ion source; the first power supply device is connected with the filament assembly and used for providing first direct-current voltage capable of controlling electronic kinetic energy for the filament assembly. The second power supply device is connected with the quadrupole rod mass analyzer and is used for providing alternating voltage capable of scanning from low ion mass number to high ion mass number and second direct current voltage capable of controlling ion axial kinetic energy for the quadrupole rod mass analyzer; the third power supply device is connected with the ionization chamber and is used for providing third voltage capable of controlling electronic kinetic energy and ion kinetic energy for the ionization chamber; the third power supply device applies a first level and a second level to the ionization chamber in the low-quality scanning stage and the high-quality scanning stage respectively, and the first level is lower than the second level. According to the invention, the problem that the ion screening capability of the existing quadrupole mass spectrometer is lost due to the fact that the quadrupole scanning voltage approaches zero at the initial stage of mass scanning is effectively solved. According to the problem, a large number of high-abundance and high-quality ions pass through a quadrupole rod mass analyzer in a low-quality scanning interval and are detected by a detector, so that a strong interference peak is generated, a target signal is covered, instantaneous saturation of the detector is easily caused, and aging of the detector is accelerated.

The application discloses a Dewar internal atmosphere testing and analyzing device and a testing and analyzing method, which comprises a first valve, a first molecular pump, a first partition valve, a first dry pump, a quadrupole mass spectrometer, a second valve, a high vacuum gauge, a heating cover, a Dewar assembly to be tested, a heating cover support, a composite vacuum gauge, a third valve, a second molecular pump, a second partition valve and a second dry pump; the quadrupole mass spectrometer and the high vacuum gauge constitute a testing and analyzing system; the heating cover, the Dewar assembly to be tested and the composite vacuum gauge constitute a gas accumulation heating system; the first dry pump, the first partition valve, the first molecular pump and the first valve constitute a main pumping system; the second dry pump, the second partition valve, the second molecular pump and the third valve constitute an auxiliary pumping system; and the testing and analyzing system and the gas accumulation heating system are connected through the second valve. The application adopts a static accumulation method to improve sensitivity and adopts independent pumping to avoid that equipment pollutes the gas accumulation heating system.

The present invention relates to the technical field of gas-phase reaction dynamics of sample ions and molecules, and in particular to an in-situ device for studying the dynamics of ion-molecule reactions, comprising: a main cavity assembly; an electrospray ion source assembly; an ion funnel assembly disposed in the main cavity assembly and connected to the electrospray ion source assembly; a guide assembly disposed in the main cavity assembly; a quadrupole mass analyzer disposed in the main cavity assembly; a linear ion trap disposed in the main cavity assembly, wherein gas-phase ions react with target gas in the linear ion trap; and a detector for acquiring and receiving signals. The device can perform structural analysis of sample components and ions generated therein, further react in the ion trap, introduce molecular dynamics into an electrospray mass spectrometer, and obtain information such as a clear reaction channel, reaction rate, and reaction efficiency. Liquid-phase sampling is implemented, thereby improving ion transmission efficiency and analytical performance, as well as multi-stage tandem analysis efficiency and sensitivity.

The present invention discloses an assembly device for a quadrupole mass analyzer, which belongs to the field of mass spectrometry technology. A connecting plate receives a fixed barrel of a quadrupole mass analyzer, and two mounting ends receive two ends of a pole of the quadrupole mass analyzer respectively. Each mounting end is provided with a mounting groove, and the end of the pole is located in the mounting groove. A tensioning member is mounted on the mounting end and cooperates with the pole to tighten each pole. A differential head is rotatably mounted on the mounting end and extends into the mounting groove. The end of the differential head contacts the pole to move the pole in the mounting groove to adjust the relative position between the four poles. The present application only requires common parts such as a differential head to adjust the position of the pole, and does not require high-precision parts that are difficult to process. Since the differential head rotates to contact the pole to adjust the position of the pole, the assembly device can assemble quadrupoles of different sizes, and has strong versatility. The present invention also relates to an assembly method for a quadrupole mass analyzer implemented by the above-mentioned assembly device for a quadrupole mass analyzer.

The invention relates to a quadrupole rod mass analyzer based on nonlinear dynamic change of resolution and application thereof, the quadrupole rod mass analyzer comprises an FPGA (Field Programmable Gate Array), a digital-to-analog converter, a comparator, a chopping differential converter, a power amplifier and a high-voltage converter which are connected in sequence, and the output of the high-voltage converter is also connected to the comparator through a feedback attenuation circuit; the FPGA and digital-to-analog converter is used for setting the output voltage of the radio frequency power supply and converting and outputting the output voltage; the comparator is used for carrying out error comparison on the preset voltage and the voltage fed back by the radio frequency high voltage so as to output error voltage; the chopping differential converter is used for chopping the error voltage and filtering to screen out a fundamental frequency signal; the power amplifier is used for performing power amplification on the fundamental frequency signal, and a primary coil of the high-voltage converter is driven by a half bridge; and the feedback attenuation circuit is used for attenuating AM amplitude modulation signals of the high-voltage converter, detecting and feeding back the AM amplitude modulation signals to the comparator for comparison. According to the invention, the non-linear relation between RF and DC voltage is precisely controlled, so that the resolution capability of different mass intervals is dynamically optimized.

The invention discloses an EI source quadrupole mass spectrometer of an electrostatic lens and ion trap composite structure and a control method, and relates to the technical field of ion transmission, the EI source quadrupole mass spectrometer comprises an EI ion source, the electrostatic lens and ion trap composite structure, a quadrupole mass analyzer and a detector which are arranged in sequence, the EI ion source is used for generating and extracting ions, and the quadrupole mass analyzer is used for detecting the EI ion source. The electrostatic lens and ion trap composite structure comprises an electrostatic lens assembly and a miniature ion trap, and the electrostatic lens assembly is used for dynamically adjusting voltage according to the molecular weight of ions, forming a gradient electric field, achieving accurate collimation and focusing of ion beams and improving the ion transmission efficiency. The micro ion trap is used for temporarily storing and enriching ions and increasing the number of ions entering the quadrupole rod mass analyzer, the quadrupole rod mass analyzer is used for carrying out mass scanning and screening on the ions, and the detector is used for detecting the screened ions, so that the detection precision of a low-concentration trace organic matter sample is improved.

The present invention provides a quadrupole mass analyzer. The ion source (21) of the quadrupole mass analyzer (100) has: a filament (211) which is subjected to a voltage to release electrons; an ionization chamber (212) which provides electrons to ionize the sample; and a blocking member (214) disposed between the filament (211) and the ionization chamber (212) to block the movement of a coating forming a film that forms a coating in the ionization chamber (212) into the ionization chamber (212).

A quadrupole mass spectrometer includes a quadrupole mass filter including: a main rod portion including four main rod electrodes; a pre-rod portion including four pre-rod electrodes, where, at an end opposite to the main rod portion, the four pre-rod electrodes are disposed to be aligned on an inscribed circle having the same radius centered on the ion optical axis, and, at the other end facing the main rod portion, two pre-rod electrodes facing each other across the ion optical axis and the other two pre-rod electrodes are disposed to be aligned on an inscribed circle having different radii centered on the ion optical axis; a main voltage applying unit to apply, to each main rod electrode, a voltage created by superimposing a DC voltage and an RF voltage; and a pre-voltage applying unit to apply an RF voltage having a same frequency as the RF voltage to each pre-rod electrode.

The present invention relates to the technical field of mass spectra. Disclosed are a novel ion storage system and method based on a quadrupole-ion trap tandem mass spectrometry. The system sequentially comprises a heating capillary, a tube lens, a skimmer, a first ion guide, a second ion guide, a quadrupole mass analyzer, an ion trap mass analyzer, and a detector; a first lens is provided between the first ion guide and the second ion guide; a second lens and a third lens are provided between the second ion guide and the quadrupole mass analyzer, wherein operation modes of the first ion guide and the second ion guide comprise an ion transmission mode and an ion storage mode. Compared with conventional time sequence control methods, more ions are stored during the same time according to the present invention, thereby improving the sensitivity of the instrument.

The present invention discloses a method for assembling a quadrupole mass analyzer, belonging to the field of mass spectrometry analysis. The method includes steps such as device construction, electrode rod pre-placement, electrode rod position measurement and adjustment, ceramic ring installation, ceramic ring fixation, and device disassembly. Through the above steps, the quadrupole field circle accuracy is completely determined by the mandrel processing accuracy, reducing the dimensional chain; the assembly process difficulty is reduced, and the electrode rod position adjustment during the process becomes simpler; the field-diameter ratio control of the quadrupole becomes more precise, and the tolerance band of the electrode rod group rod diameter is widened, reducing the process difficulty and improving the yield rate. The present invention also relates to a quadrupole mass analyzer assembly device that implements the above quadrupole mass analyzer assembly method.

The invention relates to a photoionization light intensity selectable quadrupole mass spectrometer and a use method thereof. The photoionization light intensity selectable quadrupole mass spectrometer comprises a light source cavity, a main cavity, a quadrupole mass analyzer, a photomultiplier, a molecular pump and a light intensity selection assembly. The light intensity selection assembly is used for selecting light intensity; the main cavity comprises an ionization chamber and an analysis chamber, an ion collimating lens for focusing ions formed by ionization is mounted in the ionization chamber, and the focused ions enter the analysis chamber through a through hole; the quadrupole rod mass analyzer is used for screening ions with different mass-to-charge ratios and sending the ions into the photomultiplier, the photomultiplier is used for amplifying an ion current signal and sending the ion current signal to the processor for processing, and the processor is used for detecting gas to be detected. The light intensity of the light beam entering the ionization chamber is selected through the light intensity selection assembly, flexible selection of the light intensity of photoionization is achieved, the complex operation of light intensity selection of a traditional photoionization mass spectrum system is greatly optimized, and the working efficiency of the mass spectrum system is greatly improved.