The application discloses a preparation method of tetramethoxysilane and application of the tetramethoxysilane, and the preparation method comprises the following steps: S1, adding a suspended agent after
impurity removal,
silicon powder and a pretreatment catalyst into a reactor, controlling a
reaction temperature to be 180-280 DEG C, introducing
methanol from the bottom of the reactor, and stirring to obtain a crude product; and S2, rectifying the crude product at 90-120 DEG C to obtain the tetramethoxysilane. By using the suspended agent after
impurity removal, the
silicon powder, the pretreatment catalyst and the
methanol are uniformly dispersed in the suspended agent and react, so that the reaction is more sufficient; the tetramethoxysilane prepared by using the method has extremely low
chlorine content, the
organic content of the product is greater than 99.99%, the total content of
metal element impurities is less than 25 ppm, the total content of
potassium,
lithium and
sodium is less than 2.5 ppm, is suitable for synthesizing high-purity
quartz, and the product can be simultaneously applied to
chemical vapor deposition and
sol-
gel method for producing high-purity
quartz.