89 results about "Mesoporous organosilica" patented technology

The present invention provides a new class of organic / inorganic hybrid materials having [ER]n rings interconnected by E′ atoms. In an embodiment a class of materials called high organic group content periodic mesoporous organosilicas (HO-PMO's) with [SiR]3 rings interconnected by O atoms is described. The measured dielectric, mechanical and thermal properties of the materials suggest that an increased organic content achieved by the [SiR]3 rings of a high organic group content periodic mesoporous organosilica leads to superior materials properties potentially useful for a wide range of applications including microelectronics, separation, catalysis, sensing, optics or electronic printing.

The invention discloses a preparation method of a mesoporous silica nanosphere having a dendrimer-like open-framework structure. In this method, the template is cetyl trimethyl p-toluene sulfonic acid ammonium salt, the alkaline source is small organic molecule amine, the silicon source is tetra alkyl silicate ester, and the regulating agent for particle growth is a room temperature short-chain ion liquid; the mole ratio of the silicone source: template: small organic molecule amine: room temperature or low-temperature short-chain ion liquid: water is 1:0.001-0.6:0.001-8.0:0.001-100:20-1000, and effective modulation can be achieved when the particle size is in a range of 150 to 800 nm. The mesoporous nanosphere synthesized by the method has a uniform size, a specific surface area of 1000 m<2> / g, a hole volume of 2.0 ml / g, and a hole size of 3 to 20 nm; and the nanosphere has a prominent diverging open-framework structure from the inside to the outside, namely the dendrimer-like open-framework structure. The preparation method has the advantages of simple preparation and low synthesis cost.

A catalyst system comprising a combination of: 1) an activator; 2) one or more metallocene catalyst compounds; 3) a support comprising an organosilica material, which is a mesoporous organosilica material. The organosilica material is a polymer of at least one monomer of Formula [Z1OZ2 SiCh2]3(i), where Z1 represents a hydrogen atom, a C1-C4 alkyl group, or a bond to a silic-on atom of another monomer and Z2 represents a hydroxyl group, a C1-C4alkoxy group, a C1-C6 salkyl group, or an oxygen atom bonded to a silicon atom of another monomer. This invention further relates to processes to polymerize olefins comprising contacting one or more olefins with the above catalyst system.

The invention provides a method for preparing extra-large pore diameter hollow mesoporous organic silicon nanoparticles. The method comprises the following steps: (1) mixing solid SiO2 microspheres, a surfactant solution, water and ammonia water, adding an organic silicon source under stirring conditions, reacting, thereby obtaining solid core SiO2 microspheres or organic silicon microspheres of mesoporous shell structures; (2) dispersing the solid core SiO2 microspheres or organic silicon microspheres of mesoporous shell structures in an alkaline solution, etching to remove the solid cores, and separating the solid products; and (3) dispersing the solid products in water, performing hydrothermal treatment for the specified time, thereby obtaining the organic silicon microspheres of the extra-large pore diameter hollow mesoporous shell structures.

The present invention discloses a modification method for an ordered mesoporous organosilicon material. The method comprises that: a cyclic oligomer and a coupling agent are subjected to a first contact reaction, and then the product obtained after the reaction and an ordered mesoporous organosilicon material are subjected to a second contact reaction, wherein the cyclic oligomer has hydroxyl, the general formula of the coupling agent is O=C=N-R1-Si-(OR2)3, R1 is C1-C10 alkylidene, and R2 is C1-C10 alkyl. The modified ordered mesoporous organosilicon material prepared according to the method has the excellent absorption performance.

The invention relates to a multilevel porous / mesoporous organic silicon ball and a preparation method thereof, in particular to a multilevel porous / mesoporous silica nanoparticle. The silica nanoparticleis of a multilevel porous structure having large apertures and small apertures at the same time, and comprises a mesoporous silica ball and a dendritic organic silicon envelope layer, wherein the surface of the mesoporoussilica ball is wrapped by the dendritic organic silicon envelope laye, mesoporous aperture of the mesoporous silica ball is smaller than 2nm, and the mesoporous aperture of the dendritic organic silicon envelope layer is 4-9nm. The multilevel porous / mesoporous nanoparticle disclosed by the invention has the advantages of good dispersion, large specific surface area, large pore volume and uniform and adjustable aperture distribution.

The invention discloses a preparation method of imidazole functionalized amphiphilic periodic mesoporous organic silicon material. The method comprises the following steps of: synthesizing functionalized vinyl imidazole by 1-vinyl imidazole and 1, 3-propane sultone, forming a functionalized silicon source containing imidazole group by clicking triethoxysilane with the functionalized vinyl imidazole, slowly hydrolyzing the silicon source and 1, 2-di(triethoxy silicon base) ethane (BTEE) under the action of special surfactant and strong acid to form the PMO (Periodic Mesoporous Organosilicas) material with specific appearance. The PMO material prepared by the above technology has the following advantages that the material in the invention has better appearance and higher regularity; the material in the invention has a lipophilic group, and also can be modified with hydrophilic group later, so that the material can play due role in a wider field; the method in the invention has simple steps, is easy to operate, and can modify the groups having special functions according to actual needs, so that the method has certain development space.

The invention discloses a preparation method of an N-(4-toluenesulfonyl)-1,2-diphenyl ethylenediamine functionalized hollow PMO (Periodic Mesoporous Organosilica) catalyst. The hollow PMO catalyst can be better dispersed into an organic or inorganic solvent, as a result, compared with a traditional PMO material, the hollow PMO catalyst can remarkably increase the reaction speed on the basis of the speed of the traditional PMO catalyst. The catalyst prepared by the preparation method has the following advantages: (1) the reaction speed is further increased; (2) a series of catalysts can be synthesized through coordinating different metals with the catalyst; (3) the catalyst can be better dispersed into a reaction system.

The invention discloses a mesoporous organosilica nanosphere adopting a double-layer yolk-eggshell structure and a preparation method. The mesoporous organosilica nanosphere is a spherical body with an inner-layer hollow structure and an outer-layer hollow structure, wherein the inner layer contains a thioether bond, the outer layer contains an ethane group, and mesoporous channels are formed in the inner layer and the outer layer. Two kinds of organosilicone sources are adopted, organosilane bis(gamma-(triethoxysilyl) propyl) tetrasulfide containing the thioether bond (-(CH3)3-S4-(CH3)3-) and organosilane 1.2-bis(triethoxysilyl) ethane containing the ethane group (-CH2-CH2-) are added to a reaction solution sequentially, and synthesized organosilica has good hydrothermal stability and chemical activity with introduction of the two kinds of organosilicone sources; the mesoporous organosilica nanosphere has a regular shape and uniform size, agglomeration of particles is avoided, a large cavity is formed between the inner layer and the outer layer, and the mesoporous organosilica nanosphere has excellent dispersibility and biocompatibility and has huge application potential in the aspects of catalysis, drug delivery and the like.

The invention discloses a method for detecting uric acid by using mesoporous organic silicon hollow nanosphere fixed uricase, and belongs to the technical field of uric acid detection. The experimenttakes monodispersed SiO2 nanospheres as a hard template, and adopts a one-step growth-induced corrosion method to prepare mesoporous organic silicon hollow nanospheres. The method is simple and easy to operate, is low in requirement and highly controllable in synthesis process, and can synthesize hollow-structured mesoporous organic silicon nanospheres with different functional groups by using different precursors. The synthesized mesoporous organic silicon hollow nanospheres have ordered pore channels and uniform pore diameters, and internally contain hollow cavities. The synthesized mesoporous organic silicon hollow nanosphere fixed uricase is used to detect serum uric acid, so that the method for detecting uric acid by using the mesoporous organic silicon hollow nanosphere fixed uricaseis established, and an application prospect in rapid detection of serum uric acid is achieved.

Provided photo-decontamination catalyst material comprising an optically active molecule embedded / incorporated / bridged in a periodic mesoporous organosilica (PMO). The optically active molecule is a typically a fluorophore or chromophore, more specifically, a porphyrin or phthalocyanine. The periodic mesoporous organosilica can be a template directed molecularly imprinted periodic mesoporous organosilica. The PMO material incorporating an optically active molecule is useful as a catalyst in photo-decontamination applications, as well as a detection element for stand-off point detection system.

The invention discloses a molecular sieve core-mesoporous organosilicon hollow shell hierarchical porous composite material and a preparation method thereof, and belongs to the technical field of nano-composite materials. The hierarchical porous composite material adopting a traditional molecular sieve as a core and mesoporous organosilicon as a shell and generating large hollow cavities is prepared through combining a Stober process with a growth-induced corrosion process for the first time. The outer surface of the molecular sieve is coated with a mesoporous silica layer by the simple Stoberone-step synthesis process to obtain a double-layer core-shell structure, and a silicic acid species, obtained by hydrolysis and self-polymerization of organic organosilane and dissolving of the silica shell under an alkaline condition, is copolycondensed with an oligomer generated by hydrolysis of organosilane in the presence of a surfactant with the double-layer structure as a hard template bythe growth-induced corrosion process to obtain the mesoporous organosilicon shell in order to finally prepare the target product. The material can be widely applied to the fields of catalyzed green organic reactions and adsorption separation.

The invention discloses a preparation method for visible photosensitized periodic mesoporous organosilica (PMO) near-infrared luminescence material grated with a rare earth complex, which comprises the following steps of: modifying 2,2'-bipyridine to prepare a bifunctional ligand bpd-Si; on the basis, synthesizing 2,2'-bipyridine functionalized PMO material (bpd-PMO) by the copolycondensation; meanwhile, preparing a binary rare earth complex Ln(dbm)3(H2O)2(Ln=Er, Yb and Nd); then, mixing products obtained in the previous two steps; taking ethanol as solvent; flowing back under stirring; and washing and drying the obtained solid product to obtain mesoporous hybrid material Ln(dbm)3bpd-PMO(Ln=Er, Yb and Nd) of which the rare earth complex is covalently grafted to a PMO material skeleton. According to the visible PMO near-infrared luminescence material grated with the rare earth complex, the 2,2'-bipyridine functionalized PMO is used as a matrix, and the near-infrared luminescence rare earth complex Ln(dbm)3(H2O)2(Ln=Er, Yb and Nd) is covalently grafted to the hole wall of the PMO material by the ligand exchange reaction to obtain one type of luminescence material which has the mesoporous characteristics and can emit the near-infrared light under the stimulation of visible light.

The invention discloses a preparation method of a phase change composite material with a high phase change enthalpy. The preparation method comprises the following steps: (1) synthesizing nano-flower-shaped mesoporous organic silicon; and (2) preparing shape-stabilized the phase change composite material by taking the nano-flower-shaped mesoporous organic silicon as a carrier. The preparation method disclosed by the invention has the advantages that the nano-flower-shaped mesoporous organic silicon is taken as the carrier for fixing PEG (polyethylene glycol) to prepare the shape-stabilizedphase change composite material, so that the crystallization behavior of PEG molecules is improved, and the phase change enthalpy of the shape-stabilized phase change composite material is increased; the PEG modified by GO forms a cross-linked network, so that the stability of the phase change composite material is increased; and interior of the network of the PEG is filled with the GO to form afilled structure, so that the thermorheological behavior and the crystallization behavior of the phase change composite material are effectively improved.

The invention discloses a nano-drug for tumor ferroptosis-gas synergistic treatment. The nano-drug comprises biodegradable hollow mesoporous organic silicon nano particles, carbonyl iron compounds loaded in the hollow mesoporous organic silicon nano particles and a small molecule drug. The invention further discloses a preparation method of the nano-drug for tumor ferroptosis-gas synergistic treatment and application of the nano-drug to preparation of tumor treatment drugs. The preparation method is simple to operate and can be used for repeated large-scale preparation. According to the nano-drug disclosed by the invention, sulfur-sulfur bonds are introduced to react with over-expressed glutathione in a tumor micro-environment, so that a hollow mesoporous organic silicon skeleton is broken, the loaded small-molecule drug is released, and the whole nano-drug is degraded; and the loaded carbonyl iron compound responds to excessive hydrogen peroxide in a tumor micro-environment, so that CO can be released, ferroptosis can be realized, and the synergistic effect of gas treatment and ferroptosis can be realized.

The invention discloses a novel copper sulfide based high-efficiency anti-tumor composite material and a preparation method and application thereof. The method comprises the following steps of preparing copper sulfide nanoparticles in a sodium alginate aqueous solution, co-loading the copper sulfide nanoparticles and glucose oxidase to mesoporous organic silicon, and performing quick synthesis toobtain the novel copper sulfide based high-efficiency antitumor composite material. The composite material has the advantages of being convenient to prepare, convenient to use, notable in anti-tumor effects and the like. Compared with the prior art, the composite material utilizes the thermal effects and photodynamic effects of the copper sulfide nanoparticles in a united manner; the glucose oxidase is added, the photodynamic effects of the copper sulfide nanoparticles can be notably reinforced, and high-efficiency tumor treatment based on nanometer copper sulfide can be realized. The composite material has important application value in the field of photoinduction high-efficiency tumor treatment.

The invention discloses a preparation method of a pH-responsive degradable hollow mesoporous organosilicon nanoparticle. The preparation method comprises the following steps: at first, preparing a pH-sensitive micromolecule containing an acetal group; and then introducing the pH-sensitive micromolecule in a housing skeleton of the hollow mesoporous organosilicon nanoparticle to obtain the pH-responsive degradable hollow mesoporous organosilicon nanoparticle. A hollow mesoporous structure ensures that when being used as an anti-tumor drug carrier, the organosilicon nanoparticle has relatively high drug loading capacity; and under the weak acid condition, the organosilicon nanoparticle can be degraded, so that the loaded drug can be efficiently released, the degradation of the organosiliconnanoparticle ensures the safety metabolism of the carrier, the toxicity enrichment is avoided, and more selectivity is provided for preparing the anti-tumor drug carrier.

The invention discloses flexible mesoporous organosilicone nanorods and a preparation method and application thereof. The flexible mesoporous organosilicone nanorods have a stick-like morphology, crimping surfaces, large internal cavities and mesoporous channels; during preparation, gold nanorods are used as an inner core, a flexible mesoporous organic silicon oxide shell layer is obtained throughetching of an alkaline solution, and a skeleton contains organic silicon oxide and inorganic silicon oxide at the same time. The preparaiton technology process of the flexible mesoporous organosilicone nanorods is simple, the finished product is lower in Young modulus and higher in cytophagy efficiency, and the flexible mesoporous organosilicone nanorods have a great application potential in thefields of drug delivery, nanometer medical imaging and the like.

The invention relates to an ionic liquid-modified mesoporous material and a preparation method, which is characterized in that a SBA-15 mesoporous material precursor prepared by a sol-gel method and a transition metal-supported methoxy silicon source-bridged bis-imidazole ionic liquid as organic modification groups, and copolycondensation is employed for preparing ionic liquid-modified mesoporous material. The mesoporous material can be expressed by a general formula M-BIM-PMO, M is one or more of transition metals Co, Cu, Mn, Zn and Ni, BIM is the bis-imidazole ionic liquid such as one or more of 1,2- bis-imidazole ethane 1,3-bis-imidazole propane, and 1,4-bis-imidazole butane 1,5-bis-imidazole pentane ionic liquid, PMO is bridged organic group midified mesoporous material, which can be defined as the ordered mesoporous organosilicon material. The ionic liquid modified mesoporous material has the advantages that the dispersion of the organic group is uniform, channels are not obstructed, the specific surface area is large, and the organic ingredient is difficult to lose. The mesoporous material has wide application prospect on the aspects of catalysis and adsorption.

The invention discloses a synthetic method of mesoporous organosilica hollow nanoparticles with asymmetric morphology. The synthetic method comprises the following steps: SiO2-core nanoparticles are prepared with the St ber process; double-Si-based organoalkoxysilane is taken as a silicon source, a cationic surfactant is taken as a pore forming material, and the SiO2 nanoparticles are coated with an organic functional group hybridized SiO2 layer; a SiO2 core of a core-shell material SiO2-PMOs is removed through etching with Na2CO3, HF or ammonia water, and organic functional group hybridized SiO2-based hollow nanoparticles are obtained; a hydrochloric acid-ethanol solution or a NaCl-methanol solution is used for extracting the pore forming material in the organic functional group hybridized SiO2-based hollow nanoparticles, and the mesoporous organosilica hollow nanoparticles with the asymmetric morphology are obtained. The problem that the application of the mesoporous organosilica hollow nanoparticles is limited greatly due to the fact that the morphology, the nanostructure, the composition and the particle size of the mesoporous organosilica hollow nanoparticles are difficult to regulate and control in the prior art is solved.

The invention discloses a covalent bond adjustable colloid molecular structure magnetic mesoporous organic silicon composite microsphere and a preparation method thereof. The preparation method comprises the following steps: preparing water-soluble magnetic ferroferric oxide (Fe3O4) nanoparticles by adopting a solvothermal method; the preparation method comprises the following steps: by taking tetraethyl orthosilicate and dialkyl organosilane as silicon sources and taking a cationic surfactant as a pore-foaming agent and a nucleating agent, carrying out heterogeneous nucleation on the surfacesof Fe3O4 nano-particles and growing organic functional group hybridized silicon oxide spheres to obtain magnetic organic silicon composite microspheres with colloidal molecule structure; regulating and controlling the number of covalent bonds of'colloid molecules' by controlling the sol-gel reaction of the silicon source precursor; and removing the pore-foaming agent in the organic functional group hybridized silicon oxide spheres by adopting an ammonium nitrate ethanol solution to obtain the covalent bond adjustable magnetic mesoporous organic silicon composite microspheres with colloidal molecule structures. The invention provides a controllable preparation method of composite microspheres with the colloidal molecule structure.

The invention discloses a preparation method of periodic mesoporous organosilica (PMO) magnetic ball Fe3O4@PMO material. The synthesis route of the material comprises the following steps of: uniformly dispersing magnetic ferroferric oxide particles into an aqueous solution containing a template agent and alkali, then heating to 80 DEG C, then dropping an organic silicon source, hydrolyzing the silicon source in the presence of the alkali, wrapping the hydrolyzed silicon source on the surface of the magnetic ferroferric oxide in the presence of the template agent so as to form magnetic balls, removing the template agent by using an organic solvent for refluxing, and finally forming the target product Fe3O4@PMO in a mesoporous core-shell structure. The preparation method has the advantages that (1) as a large quantity of silicon hydroxyls are adsorbed on the surface of the material, functional groups can be further modified, so that the material can be widely applied to the fields of catalysis and sewage treatment; (2) the material synthesized through the preparation method can be conveniently and rapidly recycled only by additionally arranging a magnet; and (3) the magnetic material acquired through the preparation method is more uniformly dispersed than conventional magnetic materials, and the synthesis route of the material is simple and convenient.

The invention discloses an ethylenediamine functionalized three-dimensional ordered mesopore organosilicone immobilized Pd(II) catalyst. A preparation method of the Pd(II) catalyst comprises the following steps: firstly carrying out copolycondensation on ethylenediamine bridged silane and phenyl bridged silane in presence of a surfactant to obtain an ethylenediamine functionalized three-dimensional ordered mesopore organosilicone material; and then immobilizing Pd(II) on the ethylenediamine functionalized three-dimensional ordered mesopore organosilicone material to obtain the ethylenediamine functionalized three-dimensional ordered mesopore organosilicone immobilized Pd(II) catalyst. The ethylenediamine functionalized three-dimensional ordered mesopore organosilicone immobilized Pd(II) catalyst can be used for solving the problems that a homogenous Pd(II) catalyst can not be recycled and heavy metal ions and an organic solvent can produce pollution to the environment, is of an ordered three-dimensional hexagonal mesopore structure, has high specific surface area and shows high catalytic activity in water phase Suzuki reaction.

The invention belongs to the technical field of photodynamic therapy, and discloses a photodynamic nano platform with a mitochondrial targeting characteristic and a preparation method and application thereof. The photodynamic nano platform with the mitochondrial targeting characteristic is composed of flexible mesoporous organic silicon oxide, mitochondrial targeting molecules and a photosensitizer, has a collapsed surface, a large internal cavity and mesoporous channels, can efficiently load drugs and has an efficient cell uptake characteristic. The preparation method comprises the following steps: etching through an alkaline solution to obtain the flexible mesoporous organic silicon oxide shell layer, and functionally modifying the mitochondrial targeting molecules and the photosensitizer Ce6 on the surface of the flexible mesoporous organic silicon oxide shell layer. The flexible mesoporous organic silicon nanoparticles are combined with a mitochondrial targeting function, so that the intracellular phagocytic efficiency, the mitochondrial targeting capability and the photodynamic therapy effect are improved. The preparation method is simple and easy to obtain, and the obtained product is high in yield and has huge application potential in the fields of tumor photodynamic therapy and the like.

The invention relates to an application of a normal paraffin isomerization catalyst. The normal paraffin isomerization catalyst is used for an isomerization reaction of C4-C8 normal paraffin. According to the application, a preparation method of the normal paraffin isomerization catalyst comprises the following steps of: dissolving 7.91 g of octadecyl trimethyl ammonium chloride into 224.0 mL of a NaOH water solution with the concentration of 3 mol / L, and then adding 11.0 g of bis(triethoxysilyl)ethane and 2.04 g of 3-thiopropyl triethoxy silane; stirring at room temperature for 20 hours, stirring at 95 DEG C for 24 hours, and filtering to obtain white sediments; washing the sediments at 70 DEG C for 12 hours by using 200 mL of an ethanol solution which contains 3.0 g of 36 percent by mass of hydrochloric acid to remove a surface active agent; treating at room temperature for 24 hours by using 65 percent by mass of HNO3 to obtain a product; and washing the product by using hot water to remove the HNO3, and drying to obtain the normal paraffin isomerization catalyst. The reaction is higher in activity and selectivity and stable in reactivity without environment pollution or equipment corrosion.

The invention provides a fluorescent material which contains an ordered mesoporous material and a modified silicon nanocrystal. The modified silicon nanocrystal is prepared by performing silicon hydrogenation reaction on a silicon nanocrystal and silane compounds of which the general formula is R1Si(OR2)3. The invention also provides a preparation method of the fluorescent material, which comprises the following step: in the presence of an organic solvent, mixing and contacting the modified silicon nanocrystal and the ordered mesoporous material, wherein the modified silicon nanocrystal is prepared by performing silicon hydrogenation reaction on the silicon nanocrystal and silane compounds of which the general formula is R1Si(OR2)3. The invention also provides application of the fluorescent material as a drug conduction carrier. The fluorescent material has fluorescent characteristic, and has the advantages of high capacity for resisting photofading and better drug slow-release property.

The present invention discloses a mesoporous silicon fluorescent nanometer material preparation method, which comprises that: (1) organic silane-modified carbon quantum dots are obtained by using a high temperature cracking method; and (2) with the hydrolysis condensation polymerization of tetraethyl orthosilicate and the modified carbon quantum dots under an alkaline condition, the ordered mesoporous organosilicon fluorescent nanometer material is obtained through a one-step method. Compared to the fluorescent nanometer material in the prior art, the fluorescent nanometer material of the present invention has the following characteristics that the carbon quantum dots are doped in the pore walls instead of the pore channels, the material has smooth and ordered mesoporous pore channels, can be subjected to two-photon excitation, has adjustable fluorescence emission, is monodispersed spherical or ellipsoidal particles, and has small particle size, and the silicon-based material has advantages of low toxicity, good biocompatibility and the like, such that the material of the present invention has wide application prospects in the fields of traceable drug delivery, multi-channel fluorescent biological imaging, and the like.

The invention discloses photoresponsive degradable hollow mesoporous organic silicon nano composite particles as well as a preparation method and application thereof. The preparation method comprisesthe following steps: firstly, preparing a bridged alkoxy silane precursor containing anthraquinone groups; and then introducing the precursor into a shell framework of hollow mesoporous organic silicon nano-particles to obtain hollow mesoporous organic silicon nano-particles, and modifying graphene oxide quantum dots on the surface to obtain the photoresponsive degradable hollow mesoporous organicsilicon nano composite particles. The hollow mesoporous structure ensures that the nano-particles have high drug load when being used as anti-tumor drug carriers; and under the condition of illumination, the nano composite particles can be degraded, so that not only can the loaded drugs be efficiently released, but also the self-degradation ensures the safe metabolism of the carriers and avoids enrichment of toxicity.