Preparation method of mesoporous silica nanosphere having dendrimer-like open-framework structure

Abstract

The invention discloses a preparation method of a mesoporous silica nanosphere having a dendrimer-like open-framework structure. In this method, the template is cetyl trimethyl p-toluene sulfonic acid ammonium salt, the alkaline source is small organic molecule amine, the silicon source is tetra alkyl silicate ester, and the regulating agent for particle growth is a room temperature short-chain ion liquid; the mole ratio of the silicone source: template: small organic molecule amine: room temperature or low-temperature short-chain ion liquid: water is 1:0.001-0.6:0.001-8.0:0.001-100:20-1000, and effective modulation can be achieved when the particle size is in a range of 150 to 800 nm. The mesoporous nanosphere synthesized by the method has a uniform size, a specific surface area of 1000 m<2> / g, a hole volume of 2.0 ml / g, and a hole size of 3 to 20 nm; and the nanosphere has a prominent diverging open-framework structure from the inside to the outside, namely the dendrimer-like open-framework structure. The preparation method has the advantages of simple preparation and low synthesis cost.

Description

technical field [0001] The invention relates to a preparation method of a mesoporous molecular sieve, in particular to a preparation method of a highly monodisperse mesoporous silicon dioxide nanosphere with a dendritic pore structure. Background technique [0002] Dendrimer-like mesoporous silica nanoparticles (Dendrimer-like mesoporous silica nanoparticles), also known as hierarchical porous nanoparticles or mesoporous silica nanoparticles with Its structural characteristics, physical and mechanical strength, and large specific surface area and pore volume have broad application prospects in the fields of targeted drug delivery, tissue engineering, gene delivery therapy, molecular imaging, non-invasive surgical synergistic therapy, and catalysis. research interests. Ionic liquids refer to salts that are liquid at or near room temperature and are composed entirely of anions and cations, also known as low-temperature molten salts. Due to the incomparable advantages of many...

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Problems solved by technology

However, there has been no literature report so far, using ionic liquids as particle growth inhibitors to prepare monodisperse colloidally stable dendritic mesoporous silica nanospheres

[0003] The synthesis of dendritic mesoporous nanoparticles has made some progress. How to make full use of these multifunctional nanomaterials to replace or improve some existing nanomaterials with obvious defects or disadvantages requires more efforts, especially The precise control of particle size (10-800 nm) and the research on the formation mechanism are still quite lacking

In 2009, Japanese scientist Okuyama's research group first reported the synthesis of large-diameter dendritic mesoporous silica spherical particles using lysine (Lysine) as an alkali source and particle growth inhibitor (Microporous Mesoporous Mater. 2009, 120, 447? 453.), but it needs the help of complex microemulsion system, the synthesis method is complicated, and the synthesis cost is high

Although the synthesis method is simple to prepare, the colloidal stability of the obtained particles is extremely poor after re-ultrasonic dispersion, and severe agglomeration and coagulation are prone to occur after a few minutes; As well as the type and amount of solvent, the size of the particles did not change significantly (~100 nm)

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