397 results about "Yeast fermentation" patented technology

The invention relates to the technical field of food processing, in particular to oat fermented milk and a preparation method thereof, and the preparation method comprises the following steps: respectively preparing bacterial suspensions of TZ3-1-2, TG8-1-9 and QF-1-1; adding the TZ3-1-2 bacterial suspension and the TG8-1-9 bacterial suspension into the oat juice, and carrying out lactic acid bacteria fermentation to obtain a lactic acid bacteria fermentation product; adding the QF-1-1 bacterial suspension into the lactic acid bacteria fermentation product for yeast fermentation to obtain a yeast fermentation product; and carrying out after-ripening catalysis on the yeast fermentation product to obtain the oat fermented milk. The lactic acid bacteria TZ3-1-2 are pediococcus pentosaceus, and the preservation number of the lactic acid bacteria TZ3-1-2 is CGMCC (China General Microbiological Culture Collection Center) No.32259; the lactic acid bacteria TG8-1-9 are lactobacillus plantarum, and the preservation number of the lactic acid bacteria TG8-1-9 is CGMCC (China General Microbiological Culture Collection Center) No.32258. The lactic acid bacteria TG8-1-9 are lactobacillus plantarum. According to the method, mixed fermentation and two-stage sequential fermentation technologies are utilized, the fermentation time is shortened, meanwhile, the defects of single fermentation are effectively overcome, and finally the oat fermented milk which is excellent in taste and good in tissue state in all aspects is obtained.

The invention discloses an ulva lactuca composite wall-breaking enzymolysis fermentation product as well as a preparation method and application thereof, and relates to the field of cosmetics. The preparation method comprises the following steps: soaking ulva powder, and performing physical cell wall breaking treatment; mixed enzymes are added for an enzymolysis reaction, wherein the mixed enzymes comprise lipase, cell wall breaking enzyme, enzyme and protease; adding the enzymolysis product into a culture medium, and inoculating bacterial liquid for fermentation culture to obtain fermentation liquid. According to the application, active ingredients such as macromolecular polysaccharide and protein in the ulva lactuca are extracted and decomposed by adopting physical cell wall breaking, composite enzymolysis and bifidus yeast fermentation technologies, and the prepared fermentation product is rich in various composite micromolecular active ingredients such as oligosaccharide, polypeptide, amino acid, polyphenols and flavonoids, has high free radical scavenging capacity, and can be used for preparing the ulva lactuca beverage. The anti-wrinkle and anti-oxidation composition has good anti-wrinkle and anti-oxidation effects, is beneficial to skin absorption when being applied to cosmetics and has high absorption efficiency, and the prepared cosmetics have excellent anti-wrinkle, anti-oxidation, soothing and repairing effects.

The invention relates to a skin care composition containing white truffle and plant exosome and application thereof. The skin care composition containing white truffle and plant exosome comprises white truffle extract, chlorella exosome, DNA sodium, superoxide dismutase and fermentation product filtrate, the fermentation product filtrate comprises any one or a combination of at least two of lactobacillus / soybean milk fermentation product filtrate, lactobacillus / mung bean seed extract / sodium glutamate fermentation product filtrate, bifidobacterium fermentation product filtrate or saccharomycetes / rice fermentation product filtrate. According to the invention, the white truffle extract, the chlorella exosome, the DNA sodium, the superoxide dismutase and the fermentation product filtrate are creatively combined, and the composition has unexpected synergistic interaction in the aspects of inhibiting melanin synthesis, accelerating melanin metabolism and resisting oxidation and aging. The composition is mild in performance and free of irritation and toxic and side effects, and can be applied to cosmetic products more safely.

The invention belongs to the technical field of biology, and relates to a combined method for improving the taste of cerasus humilis clear juice and increasing the content of available calcium and zinc, which comprises the following operation steps: S1, removing impurities from cerasus humilis fruits, cleaning, denucleating and crushing to obtain cerasus humilis pulp; s2, performing primary enzymolysis on the cerasus humilis fruit pulp to obtain primary enzymolysis cerasus humilis fruit pulp; s3, fermenting the cerasus humilis fruit pulp to obtain fermented cerasus humilis fruit pulp; s4, performing secondary enzymolysis on the fermented cerasus humilis fruit pulp to obtain secondary enzymolysis cerasus humilis fruit pulp; and S5, filtering, sterilizing and filling the secondary enzymolysis cerasus humilis pulp to obtain a cerasus humilis clear juice product. The combined method of high-speed dispersion machine release, pectinase enzymolysis, issatchenkia terricola fermentation and joint enzymolysis of cellulase, beta-glucosidase and alpha-rhamnosidase is utilized, the product taste is effectively improved while the yield of the cerasus humilis clear juice product is increased, and the cerasus humilis clear juice product is palatable in sourness and sweetness, clear, transparent and bright, full in flavor and suitable for large-scale production. And the contents of calcium and zinc are increased by more than 65% and 59%. The product has good calcium and zinc supplementing effects.

The invention discloses a Raman spectrum-based online detection method for glucose and ethanol in a yeast fermentation process. The Raman spectrum-based online detection method specifically comprises the following steps: preparing a yeast seed solution, and inoculating the yeast seed solution into a fermentation tank for fermentation; in the fermentation process, an immersion type Raman optical fiber probe is used for collecting a Raman spectrum in real time, and meanwhile sampling is conducted at regular time to measure the concentration of glucose and ethanol; sequentially carrying out median filtering, adaptive iteration reweighted penalty least square method (airPLS) baseline correction, Savitz-golay (SG) smoothing processing and characteristic peak normalization on the acquired spectrum; respectively establishing concentration prediction models of glucose and ethanol by adopting a PLS1 algorithm; and applying the model to a subsequent batch fermentation process to realize online prediction of glucose and ethanol. According to the method, manual sampling is not needed, prediction is accurate, operation is easy and convenient, and in-situ online detection of glucose and ethyl alcohol in the yeast fermentation engineering can be achieved.

The invention belongs to the technical field of probiotic fermentation, and discloses a preparation method and application of a bifidus yeast fermentation product, and the preparation method of the bifidus yeast fermentation product comprises the following steps: S1, preparing a medicinal phellinus igniarius extract A; s2, preparing a compound extract B of rhizoma anemarrhenae, radix puerariae, sophora flower buds and soapberry; s3, preparing a bifidobacterium fermentation product, namely inoculating the bifidobacterium seed solution into a fermentation culture medium, and culturing and fermenting under an anaerobic condition to obtain a primary fermentation liquid C; and adding A, B and a bifidobacterium seed solution into C, carrying out secondary fermentation, and carrying out post-treatment to obtain the bifidobacterium fermentation product. The obtained bifidus yeast fermentation product can reduce skin oxidative stress and inhibit inflammatory factors IL-6 and 5 alpha-reductase, is beneficial to skin absorption when externally applied, has a good transdermal effect on skin and an excellent oil control effect, can promote water-oil balance of skin, and achieves the technical effects of controlling oil, removing acnes and improving pores.

The invention provides a clostridium endophyllum engineering bacterium as well as a construction method and application thereof, and belongs to the technical field of biology, compared with a wild type strain, the clostridium endophyllum engineering bacterium can only produce acetic acid in a low-pH environment under the condition of taking CO2 and H2 as raw materials, and does not generate by-products such as ethanol, lactic acid, 2, 3-butanediol and the like. Besides, the fermentation liquor of the clostridium endophyllum engineering bacteria can be directly used as an acidic substrate to adjust the pH value of downstream yeast fermentation liquor, meanwhile, automatic addition of a carbon source is achieved, zero addition of inorganic salt in the cascade conversion process from CO2 and H2 to grease or yeast protein is achieved, and the economical efficiency and environmental friendliness of the whole process are improved.

The invention provides anti-aging moisturizing essence and a preparation method thereof, and belongs to the technical field of cosmetics. The essence is prepared from a plant extract, sodium pyrrolidone carboxylate, hexapeptide, nicotinamide mononucleotide, vitamin B5, galactose yeast fermentation product filtrate, b-glucan, sodium hyaluronate, glycerol, tranexamic acid, blue copper peptide, arbutin, nicotinamide, vitrin, a bifidus yeast fermentation product, a bifidus yeast fermentation lysate and the like. Wherein the plant extract is prepared by mixing rosemary, frankincense resin, tea flowers, sandalwood and jasmine flowers through ultrasonic extraction, comprehensive skin care is achieved from multiple angles of anti-aging, whitening, moisturizing and repairing, the overall health of the skin is guaranteed, and the skin care cream is suitable for various skin types.

The application belongs to the field of daily chemicals, and discloses a Bifidobacterium adolescentis, the classification name of the Bifidobacterium adolescentis BF23BA001 is Bifidobacterium adolescentis, the preservation number is CGMCC NO.26999, the preservation date is March 31, 2023, the preservation unit is China General Microbiological Culture Collection Center, and the preservation address is No.3, Xibahe Road, Chaoyang District, Beijing City. Compared with other similar bacteria on the market, the bacteria have unique advantages in the production of small molecule peptides and gamma-aminobutyric acid, according to the functional characteristics of the small molecule peptides and gamma-aminobutyric acid, the bacteria have significant anti-wrinkle advantages, and through subsequent functional verification, the bacteria have very important significance for further improving the whitening, brightening, repair and anti-aging effects of yeast fermentation products. In addition, the application also discloses a composition for inhibiting the generation and accumulation of lipofuscin, application based on the composition and cosmetics.

The invention discloses a method for extracting retinol from yeast fermentation liquor. The method comprises the following steps: A, extracting the fermentation liquor to obtain an extraction phase; step B, concentrating the extract phase to obtain concentrated oil; step C, purifying concentrated oil; and optionally step D, concentrating the purified eluent.

The invention discloses a method for preparing maltotetraose, and belongs to the technical field of functional sugar production. Comprising the following steps: preparing a maltodextrin aqueous solution; maltotetraose generating enzyme MFAPS-delta CBM enzyme is added, and primary saccharification is conducted for 8 h to 16 h; then adding debranching enzyme to react for 6-14 hours; finally, adding an MFAPS-wild enzyme, and carrying out secondary saccharification for 12 to 24 hours; and further performing yeast fermentation, activated carbon decoloration, ion exchange desalination and membrane separation impurity removal to obtain the maltotetraose syrup. According to the method, saccharification is divided into two stages, the advantages of two MFAPS enzymes are fully played, substrate conversion is promoted in combination with debranching, the substrate conversion rate reaches 99% or above, maltotetraose accounts for 72% or above in a crude sugar solution, and the purity reaches 98% or above after impurity removal. According to the method, the substrate conversion rate and the maltotetraose yield in the maltotetraose production process are improved, the problems of low conversion rate, high cost, high separation difficulty and the like of a traditional method are solved, the production and purification cost is reduced, and the yield and the industrialization level are improved.

The invention relates to the technical field of food processing, in particular to a grape wine or fruit wine fermentation nutritional agent and application thereof. The invention provides a grape wine or fruit wine fermentation nutritional agent which comprises the following components in percentage by weight: 85-99% of glutathione-containing yeast product and 1-15% of cellulose and / or cellulose derivatives. The yeast product and cellulose substances have an adsorption effect, can adsorb harmful substances such as medium-chain fatty acid generated in the yeast fermentation process, provides crystal nucleuses for release of carbon dioxide and accelerates release of carbon dioxide, and the more carbon dioxide is dissolved in the fermentation process, the more acid is, and the greater the damage to yeast is. According to the invention, the content of solids in the grape juice is improved and a carrier is provided for uniform distribution of yeast by utilizing the synergistic interaction of a yeast product and cellulose substances, and meanwhile, the fermentation nutritional agent disclosed by the invention can reduce the damage of harmful substances generated in the fermentation process, improve the fermentation environment and improve the fermentation effect.

The invention discloses emblic leafflower fruit polysaccharide with sugar-controlling and lipid-lowering activity as well as a preparation method and application of the emblic leafflower fruit polysaccharide. The polysaccharide is prepared by taking fresh phyllanthus emblica pulp as a raw material through hot water extraction, yeast fermentation, desorption after XAD-16 macroporous resin adsorption, alcohol precipitation, ultrafiltration and DEAE-52 cellulose column purification. The low-molecular-weight gulcomannan is separated from phyllanthus emblica for the first time, and monosaccharide composition of the gulcomannan mainly comprises glucose, mannose and galactose and contains trace rhamnose and xylose. The polysaccharide has sugar-controlling and lipid-lowering active action targets in the whole digestive tract (the upper digestive tract: glycolipid digestion and absorption enzymes alpha-amylase, alpha-glucosidase and pancreatic lipase inhibitory activity, starch hydrolysis delay, bile acid adsorption capacity and cholesterol micelle dissolution inhibition capacity; in the lower digestive tract, the multiplication promoting capacity of glycolipid metabolism-related probiotics) shows extremely high biological activity, and can be applied to food and health care products.

The invention discloses a beautifying essence which comprises the following components in percentage by weight: 1% of bifidus yeast fermentation liquor, 3% of boine, 2% of nicotinamide, 0.3% of gallnut extract, 1% of purslane extract, 0.3% of allantoin, 0.2% of centella asiatica extract, 0.3% of tocopherol extract, 0.5% of aesculus chinensis extract, 2% of vitamin E, 0.05% of xanthan gum, 0.05% of sodium hyaluronate, 0.2% of carbomer, 0.5% of p-hydroxyacetophenone, 0.5% of 1, 2-propylene glycol and the balance of water. The cleaning agent is prepared from, by weight, 0.5% of 1, 2-hexanediol, 5% of glycerin, 4% of PEG / PPG-14 / 7 dimethyl ether, 2.2% of glycosylglycerol, 0.2% of tetrahydroxypropyl ethylenediamine, 3% of polyglycerol-3, 0.05% of PDRN powder and the balance water. Effect evaluation test results show that the beauty essence can inhibit the activity of elastase and increase the content of type I collagen in human primary fibroblasts, so that the firming and anti-wrinkle effects are achieved.

The invention relates to an anti-wrinkle and anti-aging composition and application thereof. The anti-wrinkle and anti-aging composition is prepared from hydrolyzed rice protein, a bifidus yeast fermentation product lysate, dipeptide diaminobutyryl benzyl amide diacetate, adenosine, hydroxydecyl ubiquinone, ceramide NP, palmitoyl tripeptide-5, carnosine and acetyl hexapeptide-8. According to the present invention, the components achieve the synergistic effect, such that the fibroblast proliferation can be promoted, the cell metabolism can be improved, the generation of collagen, elastin and the like can be promoted, the excellent oxidation resistance can be provided, and the effects of expression line inhibition, existing wrinkle fading and long-term aging resistance can be combined.

The present invention discloses a composition with a penetration-promoting effect and a preparation method thereof, wherein the composition with a penetration-promoting effect comprises a solvent, a phase A moisturizer, a phase B moisturizer, a phase C moisturizer, a pH regulator, a thickener, a solubilizing agent, a skin conditioner, and a plant extract; wherein the skin conditioner is a compound of a bifid yeast fermentation product filtrate, decarboxylated carnosine hydrochloride, a yeast fermentation product extract, and ergothioneine; wherein the plant extract comprises an baobab seed extract, an echinacea extract, and a wood apple extract. A preparation method of a composition with a penetration-promoting effect is to uniformly stir the components of the composition with a penetration-promoting effect to obtain a composition with a penetration-promoting effect. The present application has the effect of significantly improving skin permeability, promoting effective moisturizing ingredients to penetrate into the stratum corneum of the skin, replenishing moisture for the skin from an endogenous source, and lastingly moisturizing.

The present invention belongs to the technical field of skin care, and discloses a skin repair composition and a skin care product, wherein the skin repair composition comprises the following components by weight percentage: 30-50% wheat germ oil, 1-5% ceramide 3, 1-10% sodium hyaluronate, and 40-60% bifid yeast fermentation product lysate. The present invention utilizes bifid yeast fermentation product lysate to help restore the activity of fibroblasts and keratinocytes, repair cell damage and protect the components in the extracellular matrix ECM, and further strengthens the damage repair speed of ECM by compounding sodium hyaluronate and ceramide, helps cells and extracellular matrix maintain a healthy state and quickly repair damage, and helps strengthen intercellular lipids and cell adhesion at the same time, and finally helps form a good skin surface sebum film through the synergistic effect of wheat germ oil and sodium hyaluronate, and the four cooperate with each other to significantly improve the skin repair effect.

The invention discloses a scalp care solution containing a probiotic fermentation product and a preparation method thereof, which comprises the following raw materials by weight: 87-91 parts of water, 3-5 parts of glycerol, 4-9.3 parts of probiotic fermentation products, 1.3-2.6 parts of plant extracts, 0.4-0.8 parts of 1,2-hexanediol, 0.4-0.8 parts of p-hydroxyacetophenone, 0.1-0.3 parts of carbomer, 0.1-0.2 parts of arginine, 0.1-0.15 parts of trace components, and 7-11 parts of composite nano-carrier liquid. The scalp care solution provides nutrition for scalp probiotics by adding prebiotic fermentation products, such as lactobacillus fermentation products, bifid yeast fermentation product filtrate, altermonas fermentation product extract, and bifid yeast fermentation product lysate, which is beneficial to promoting the growth of scalp probiotics and enhancing the scalp barrier, thereby achieving scalp health.

The invention discloses a rose fermented product as well as a preparation method and application thereof. According to the invention, the fermentation process is optimized, the combination of saccharomycetes, acetic acid bacteria and lactic acid bacteria is innovatively adopted for sequential fermentation, the first fermentation is saccharomycetes fermentation, the second fermentation is acetic acid bacteria fermentation, and the last fermentation is lactic acid bacteria fermentation. The fermented product effectively reduces cytotoxicity, effectively inhibits the generation of reactive oxygen species (ROS), and has a protective effect on oxidative stress injury of cells; compared with similar products, the content of effective components (flavone and total phenols) and the oxidation resistance (DPPH free radical scavenging rate, ABTS free radical scavenging rate and O2-free radical scavenging rate) are improved.

This invention relates to compositions and methods of microbial enhanced oil recovery using biochemical-producing microbes. In specific embodiments, the methods of the subject invention comprise applying a biosurfactant-producing bacteria and / or a growth by-product thereof to an oil-producing site. In preferred embodiments, the bacteria is a strain of Bacillus in spore form. In some embodiments, the methods further comprise applying the bacteria with a yeast fermentation product, an alkaline compound, a polymer, a non-biological surfactant, and / or one or more chelating agents. Advantageously, the subject invention can be useful for stimulating the flow of oil from a well, as well as dissolving scale present in an oil-bearing formation.

The invention discloses a composition with effects of removing dandruff, inhibiting bacteria and relieving itching as well as a preparation method and application thereof, and belongs to the technical field of daily chemicals. The composition is compounded with a yeast fermentation lysate filtrate, a bacillus fermentation product, a fructus kochiae extract, a red clover extract and a cacumen biotae extract; through a'micro-ecology-barrier-inflammation 'triple synergistic path, the synergistic interaction of inhibiting bacteria more quickly, relieving itching for a longer time and removing dandruff more thoroughly is realized. The relative contents of the substances are optimized, so that the efficacy is maximized, and the stability of the composition is ensured. The composition can be used as a cosmetic raw material to be applied to scalp stability maintaining essence, has a good effect of improving the scalp microenvironment, and is mild and non-irritant.

The invention relates to a composition with skin-tendering, firming and anti-wrinkle effects and application thereof. The composition with skin-tendering, firming and anti-wrinkle effects is prepared from bifidus yeast fermentation product filtrate, saccharomycetes / rice fermentation product filtrate and rose water. According to the composition disclosed by the invention, the bifidus yeast fermentation product filtrate, the saccharomycetes / rice fermentation product filtrate and the rose water are reasonably matched and have a synergistic effect, so that the composition has multiple effects of tendering skin, resisting wrinkles, tightening skin and the like.

The invention discloses an extraction method and application of lavender essential oil based on yeast fermentation pretreatment, and belongs to the technical field of plant active ingredient extraction. The method comprises the following steps: activating saccharomycetes, inoculating the saccharomycetes into a mixture containing a crushed lavender raw material and water, and fermenting at 30-38 DEG C for 20-28 hours to obtain fermentation liquor; then sterilizing and centrifuging the fermentation liquor to obtain supernate; and finally extracting the essential oil through steam distillation. Through yeast fermentation pretreatment, the lavender cell wall structure is effectively destroyed, essential oil release and active ingredient conversion are promoted, and the essential oil yield and antioxidant activity are remarkably improved. Compared with a traditional steam distillation method, the method has the advantages that the essential oil yield can be increased from 0.55% to 0.75% or above, and the DPPH free radical scavenging rate can be increased to 51.75% or above. The method is green in process and simple and convenient to operate, a new way is provided for high-value utilization of lavender resources, and the prepared essential oil can be used for developing cosmetics with anti-oxidation and anti-aging effects.

The invention discloses a highland barley rice wine fermented glutinous rice production and preparation process which comprises the following steps: selecting highland barley rice and glutinous rice according to a weight ratio of 1: 1, and cleaning and soaking the selected highland barley rice and glutinous rice; uniformly mixing the soaked highland barley and glutinous rice, and steaming to obtain mixed rice to be fermented; the fermentation distiller's yeast is prepared by mixing flavor distiller's yeast and sweet distiller's yeast according to the weight ratio of 1: 1; adding 6-8 g of fermentation distiller's yeast into each kilogram of the mixed rice to be fermented, and performing double-temperature double-yeast fermentation to obtain the highland barley rice wine fermented glutinous rice after fermentation; and sterilizing, cooling and packaging the highland barley wine fermented glutinous rice. The highland barley and the glutinous rice are used as raw materials to prepare the rice wine fermented glutinous rice, the prepared rice wine fermented glutinous rice can achieve the taste of the rice wine fermented glutinous rice prepared from rice under the double-yeast double-temperature fermentation technology, and the blank of the highland barley fermented rice wine fermented glutinous rice in China is filled.

The invention relates to the technical field of animal feed, in particular to cold-season yak supplementary feeding granules and a supplementary feeding method and application thereof. The supplementary feeding granular material for yaks in the cold season is prepared from the following components in percentage by weight: 10-13% of corn straws, 20-25% of sunflower seed shells, 35-38% of corn kernels, 9.4-10% of soybean meal, 8-10% of cottonseed meal, 0.8-1% of baking soda, 0.8-1% of table salt, 0.5-1% of feed premix and 4-5% of yeast leavening. Through a scientific formula, various nutritional ingredients needed by yaks can be provided, it is ensured that the yaks obtain comprehensive nutritional support in different growth stages, and meanwhile, high-energy nutritional ingredients can be provided to make up for a large amount of energy consumed by the yaks in the growth process; the feed can be converted into meat more efficiently, the growth speed and production benefits of the yaks are improved, and the feed has good digestibility and can be better absorbed by the yaks, so that feed waste is reduced, and the feeding efficiency is improved.

The invention belongs to the field of cosmetics, and discloses an anti-wrinkle soothing composition, application of the anti-wrinkle soothing composition and a cosmetic. Comprising the following components in parts by weight: 15-20 parts of hydroxypropyl tetrahydropyrantriol, 10-15 parts of tetrahydromethylpyrimidine carboxylic acid, 5-10 parts of a leukocyte extract, 5-20 parts of a leontopodium alpinum callus extract solution and the balance of a bifidus yeast fermentation product filtrate, through reasonable compounding of the five components, synthesis of collagen and elastin can be effectively promoted, and good anti-wrinkle and soothing effects are achieved.

The invention discloses rose fermentation liquor as well as a preparation method and application thereof. According to the method, pure rose flowers are fermented by using unique maneosporium fibuligerum, and under the condition of not additionally adding a nitrogen source, a nitrogen source or a growth factor, macromolecular substances such as polysaccharide and protein which are difficult to decompose by lactic acid bacteria can be fully hydrolyzed by using a single strain, so that more rose phenol, rose flavone, vitamin C, anthocyanin and the like are released; meanwhile, the yeast is matched with the roses, so that the rose fermentation liquid is additionally endowed with an oil control effect. The method is short in fermentation time and high in process benefit, secondary high-temperature sterilization is not needed after fermentation is finished, loss of thermosensitive volatile components of the roses is avoided, the fragrance of the roses is reserved, meanwhile, the unique ester fragrance of yeast is fused, and the prepared rose fermentation liquor is richer and lasting in fragrance level and more lasting in fragrance. The rose fermentation raw material has the advantages of multiple functions, strong efficacy and low cost, and has a good application prospect in the daily chemical industry.

The invention provides a double-fermentation thick skin factor liposome, a preparation method thereof and a cosmetic, and relates to the technical field of biomedical materials. The double-fermentation thick skin factor liposome comprises alkaloid, a double-fermentation thick skin factor, phospholipid and short-chain fatty alcohol, the dual-fermentation skinning factor comprises galactose yeast fermentation liquor, lactic acid bacteria NP and glycyrrhetinic acid. According to the double-fermentation thick-skin factor liposome provided by the invention, the double-fermentation thick-skin factor has excellent anti-aging and anti-aging effects, can remarkably improve the cell activity and enhance the skin barrier, and is prepared into a liposome form, and glycyrrhetinic acid in the double-fermentation thick-skin factor and sophocarpidine are utilized to form a supramolecular eutectic. The double-fermentation thick skin factor liposome has double advantages of the supramolecular eutectic solvent and the liposome, the double-fermentation thick skin factor is efficiently promoted to enter the skin, the skin residence rate is increased, and the local treatment effect is effectively improved to play the anti-aging effect of the double-fermentation thick skin factor liposome.

The invention relates to the field of cosmetics, in particular to a blue copper peptide composition with instantaneous cool feeling and infiltration promotion effects and a preparation method and application of the blue copper peptide composition. The composition comprises an active component copper-blue peptide and a cooling and permeation enhancing system formed by compounding at least two of menthane formylethylamine, menthone glyceryl ketal and methyl diisopropyl propionamide, and the active component can further comprise hexapeptide-11, a blue algae extract and a yeast fermentation product. The preparation method of the composition comprises three core steps of providing a water phase, adding the active ingredients and adding the cool and refreshing infiltration promoting system and other components. Through synergistic compounding of specific fresheners, on the premise that the use amount of each single component is remarkably reduced, efficient permeation promotion of the copper-blue peptide is achieved, the layered cool feeling experience which takes effect quickly and is lasting and mild is provided, the common skin irritation problem of a traditional permeation promoter or a high-concentration single freshener is avoided, and the effect is remarkable. And the transdermal patch has excellent transdermal efficiency, active matter stability and use comfort.

The invention relates to the technical field of daily chemicals, in particular to a soothing composition as well as a preparation method and application thereof. The composition is prepared from saccharomycetes fermentation lysate filtrate, peony root extract, spanishneedles herb extract, liquorice root extract, glycerol and tremella fuciformis extract. Small molecule peptides in the fermentation lysate and flavone, polyphenol and triterpenoid components in the plant extract can inhibit inflammation pathways (such as TNF-alpha, IL-6 and COX-2) in a multi-target mode, and skin redness is effectively relieved. The skin barrier repairing capability is high: the tremella acidic polysaccharide and the yeast polypeptide form a synergistic network, so that the water content of a cuticle is favorably enhanced, and barrier lipid synthesis is promoted; a polysaccharide-polypeptide cross-linked chain structure is broken through a high-shear homogenizing treatment technology, so that the wiredrawing and colloid decorous feeling of a finished product are remarkably reduced, and a refreshing skin feeling is obtained.