Weight-losing and lipid-lowering health-care product and preparation method thereof

Abstract

The invention relates to the technical field of health-care products, in particular to a weight-losing and lipid-lowering health-care product and a preparation method thereof. The weight-losing and lipid-lowering health-care product comprises chitosan, L-carnitine tartrate, polypeptide, a sweetening agent, an auxiliary protective agent and a filling agent. The invention also provides a preparation method of the composition. Compared with the prior art, the method has the advantages that the white kidney bean enzymatic hydrolysate, the trehalose and the plant extract are used as fermentation substrates for mixed fermentation, and the plant extract contains a large number of active ingredients which have the effect of promoting proliferation of probiotic strains and promoting fermentation, so that a large number of nutrient substances in the white kidney beans are dissolved out; further degrading into nutrient substances such as polypeptide, glucose, amino acid and the like which are easily absorbed by human beings; meanwhile, a large number of beneficial nutrition molecules are generated during mixed fermentation of the plant extract and the white kidney bean enzymatic hydrolysate, a large number of lipid-lowering substances can be generated, and meanwhile the good weight-losing effect is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of health care products, in particular to a health care product for reducing weight and reducing blood lipids and a preparation method thereof. Background Art

[0002] With the rapid development of the economy, people's living standards are getting better and better, which leads to people enjoying life too much and not paying attention to their lifestyle, behavior habits, and eating habits, thus causing diseases. Obesity, high blood sugar, and high blood lipids have now become one of the public health problems. Among them, overweight and obesity usually refer to excessive accumulation of body fat due to excessive food intake or changes in body metabolism, resulting in excessive weight gain and causing pathological and physiological changes or lurking in the human body. Blood lipids are the general term for neutral fats and lipid substances in plasma, and the main components are triglycerides, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol. When the level of one or more lipids in the blood increases (HDL-C decreases), and the content exceeds the normal value, it is called hyperlipidemia, or hyperlipidemia for short. Excessive blood lipids cause "thick blood", deposit on the blood vessel wall, form small plaques (commonly known as "atherosclerosis"), gradually block blood vessels, slow blood flow, and in severe cases, blood flow is interrupted, causing coronary heart disease, cerebral stroke, decreased vision, blindness, renal artery sclerosis, renal failure, limb necrosis, ulceration and other diseases.

[0003] At present, drugs used to treat obesity and blood lipids are divided into traditional Chinese medicine and Western medicine, but Western medicine has serious side effects, complicated production process, and is not easy to take for a long time; traditional Chinese medicine has poor therapeutic effect. Therefore, people began to seek health products for weight loss and lipid regulation that are both medicinal and edible and have no toxic side effects, and improve their daily diet. At the same time, health products have a relatively mild effect on the human body, and the method of "medicine and food treatment" can further reduce the side effects of drugs on the human body.

[0004] CN105685990A discloses a health product for reducing fat and losing weight, which includes the following components: antler extract, snail protein powder, sunflower seed extract, black ant extract, pineapple powder, lemon powder, carrot powder, Poria cocos and Bletilla striata, and the weight content of each component is: 10-20 parts of antler extract, 22-37 parts of snail protein powder, 9-19 parts of sunflower seed extract, 15-30 parts of black ant extract, 15-25 parts of pineapple powder, 15-25 parts of lemon powder, 30-40 parts of carrot powder, 5-15 parts of Poria cocos and 5-15 parts of Bletilla striata. Through the above method, the present invention has the effects of moisturizing the intestines and relieving constipation, reducing fat and blood pressure, is suitable for long-term use, and has a good weight loss effect.

[0005] CN101940319A discloses a new type of health care product with the functions of weight loss, lipid reduction, detoxification and beauty care. The new type of health care product with the functions of weight loss, lipid reduction, detoxification and beauty care is prepared by natto, tea polyphenols, L-L-carnitine, sea buckthorn seed oil and vitamin E. The proportion of each component (by weight percentage) is: 10-70% natto, 1.5%-20% tea polyphenols, 10-80% L-L-carnitine, 10-70% sea buckthorn seed oil, and 0.1-5% vitamin E. It is mainly used for weight loss, lipid reduction, elimination of toxins in the body, whitening skin, freckle removal and beauty, skin repair, anti-oxidation, and improvement of female menopausal syndrome. This product has the characteristics of novel raw materials, clear pharmacology, rapid weight loss and beauty effect, no rebound in weight loss, safe use, and wide range of people. It is easy to promote industrialization and has positive social and economic benefits. However, the weight loss and lipid reduction functions need to be further improved.

[0006] Therefore, the present invention discloses a weight-loss and lipid-lowering health product with a simple preparation method and excellent performance. Summary of the invention

[0007] To achieve the above object, the present invention provides a weight loss and lipid-lowering health product and a preparation method thereof.

[0008] A health product for reducing weight and lowering blood lipids comprises the following raw materials: 1-5 parts by weight of chitosan, 1-6 parts by weight of L-carnitine tartrate, 10-15 parts by weight of polypeptide, 1-5 parts by weight of sweetener, 5-12 parts by weight of auxiliary protective agent and 15-25 parts by weight of filler.

[0009] The sweetener is at least one of fructose, glucose, galactose, erythritol, maltitol and sorbitol.

[0010] The auxiliary protective agent is at least one of lecithin and coconut oil.

[0011] The filler is at least one of hydroxyethyl cellulose, gum arabic, alginate, microcrystalline cellulose and pregelatinized starch.

[0012] The polypeptide is a white kidney bean polypeptide or a functionalized white kidney bean polypeptide. Further preferably, the preparation method of the functionalized white kidney bean polypeptide is: (1) soaking white kidney bean kernels, peeling them, homogenizing them for 10-20 minutes, adjusting the pH to 8, and using ultrasonic treatment (15-20kHz, 100-300W)

[0013] 60-120min, soak overnight and then centrifuge to remove the oil layer and lower precipitate, adjust the pH to 4-5, stir for 20-30min and then centrifuge, take the precipitate and wash with water until neutral, dry to obtain white kidney bean protein powder;

[0014] (2) adding white kidney bean protein powder and trehalose to water and mixing them evenly, heating to 50-60° C., adding endoprotease, performing enzymolysis for 1-3 hours, inactivating the enzyme, filtering, and obtaining a first-grade enzymolysis solution of white kidney bean; wherein the mass ratio of white kidney bean protein powder, trehalose, and water is 1:(0.1-0.5):(40-80); and the content of the endoprotease is 0.1-0.5% of the mass of the white kidney bean protein powder;

[0015] (3) adding flavor protease to the first enzymatic hydrolysate of white kidney bean, heating to 40-50° C. for enzymatic hydrolysis for 1-2 hours, inactivating the enzyme, filtering, and obtaining a second enzymatic hydrolysate of white kidney bean; wherein the content of flavor protease is 0.1-0.5% of the mass of the white kidney bean protein powder;

[0016] (4) adding plant extract and trehalose to the secondary enzymatic hydrolysate of white kidney bean and mixing them evenly, then inoculating probiotic bacteria seed solution, fermenting and culturing at 32-38° C. for 12-24 hours, sterilizing after the fermentation, and obtaining a primary fermentation product of white kidney bean; wherein the content of plant extract is 1-10% by weight of the secondary enzymatic hydrolysate of white kidney bean; the content of trehalose is 1-6% by weight of the secondary enzymatic hydrolysate of white kidney bean; and the inoculation amount of the probiotic bacteria seed solution is 1-5wt%;

[0017] (5) Inoculating the Aspergillus niger seed liquid into the above-mentioned white kidney bean primary fermentation product, fermenting at 35-38° C. for 12-24 hours, sterilizing and filtering the supernatant after the fermentation, concentrating, and freeze-drying to obtain the functionalized white kidney bean polypeptide. The inoculation amount of the blackberry fungus seed liquid is 1-5wt%.

[0018] The plant extract is at least one of hemp seed extract, coix seed extract, bitter melon extract, and wheat germ extract. More preferably, the plant extract is a mixture of hemp seed extract and coix seed extract in a mass ratio of (1-3): (1-3).

[0019] The probiotic is at least one of Bifidobacterium bifidum and Lactobacillus plantarum;

[0020] The endoprotease is at least one of alkaline protease, neutral protease and bromelain.

[0021] Chitosan is the product of chitosan deacetylation. It is a natural cationic polymer that is non-toxic, harmless, safe, reliable, easily degradable, and has a wide range of sources and uses. Chitosan can be decomposed and absorbed, has a strong affinity with human cells, and has a strong adsorption capacity. It also has the functions of regulating immunity, pH, and hormone secretion, lowering cholesterol, blood sugar, and blood pressure, and easily excreting excess harmful cholesterol, heavy metal ions, toxins, and inhibiting the growth of cancer cells, inhibiting cancer metastasis, and inhibiting the toxins released by the proliferation of cancer cells.

[0022] When the body lacks L-carnitine, it is easy to cause lipid metabolism disorders, and lipid substances accumulate in muscle fibers and liver, resulting in obesity and fatty liver. L-carnitine can make full use of the energy converted from fat, increase its burning rate, and reduce the accumulation of excess fat; L-carnitine tartrate acts as a carrier to transport long-chain fatty acids from the outside of the mitochondrial membrane to the inside of the membrane in the form of acylcarnitine, and performs B-oxidation in the mitochondria to generate energy. L-carnitine tartrate reduces the intestinal absorption of lipid substances in food, controls the body's calorie intake, prevents new fat storage, and consumes the original excess fat in the form of heat production, speeding up the metabolic rate of fat, converting it into protein sugar, maintaining the balance of the body's original nutritional components, and playing a role in regulating human fat and blood lipids.

[0023] The protein content of white kidney bean is 19.9%-20.0%, the fat content is 1.6%-2.1%, the carbohydrate content is 37.6%-48.5%, and the Ca and Fe contents are 7 times and 4 times that of chicken, respectively, with high nutritional value; white kidney bean protein contains a natural α-amylase inhibitor, which can be used to treat obesity and diabetes, etc. Therefore, the present application provides a functional white kidney bean polypeptide, which uses white kidney bean as raw material, and uses endo-enzyme and exo-enzyme interaction to enzymolyze the white kidney bean, so that the effective active substances in the white kidney bean are effectively released, and at the same time The amino acids, proteins and other substances in white kidney beans are enzymatically hydrolyzed to form small molecule peptides; at the same time, white kidney bean enzymatic hydrolysate, trehalose and plant extracts are used as fermentation substrates for mixed fermentation. The plant extracts contain a large number of active ingredients, which can promote the proliferation of probiotic strains and promote the fermentation process, so that a large amount of nutrients in white kidney beans are dissolved and further degraded into nutrients such as polypeptides, glucose and amino acids that are easily absorbed by humans; at the same time, the plant extracts and white kidney bean enzymatic hydrolysate produce a large number of beneficial nutritional molecules during mixed fermentation, which can produce a large number of lipid-lowering substances and have a good weight loss effect.

[0024] Endoprotease, also known as endopeptidase, cuts the inside of protein molecules to form peptides with smaller molecular weight; neutral protease interacts with bromelain to hydrolyze large molecular proteins into products such as amino acids, which are easily digested and absorbed by the human body; flavor protease contains aminopeptidase and carboxypeptidase, which can hydrolyze polypeptides through the end; the present application uses endoprotease to perform the first enzymatic hydrolysis on white kidney bean protein powder, and uses flavor protease to perform the second enzymatic hydrolysis on it. The two interact with each other to form polypeptides with smaller molecular weight, thereby increasing the yield of polypeptides and making them easier to be absorbed by the human body.

[0025] The present application uses the second enzymolysis liquid as the fermentation base, and adds plant extracts at the same time, which provides a carbon source for probiotics while promoting the proliferation of probiotics, shortening the fermentation time and increasing the fermentation efficiency; Hemp seed, also known as cannabis seed, is the dried mature seed of the Moraceae plant hemp (Cannabis sativa L.), and is a traditional Chinese medicine with a long history of medicinal use. Hemp seed contains a large amount of unsaturated fatty acids, which has the effect of regulating blood lipids. Hemp seed is rich in protein, with a content of about 20%, of which the content of essential amino acid arginine is extremely high. Hemp seed protein is very easy to digest, and its digestibility reaches 88%-91%, which is significantly higher than soy protein (71%), and has excellent balanced nutrition and the effect of improving physical fitness. Studies have found that hemp seed protein can generate lipid-lowering and antioxidant polypeptide substances after enzyme and fermentation degradation. At the same time, hemp seed extract has a proliferation effect on Bifidobacterium bifidum and Lactobacillus plantarum. Coix seed extract is the seed kernel of coix seed, an annual and perennial herbaceous plant. It is flat in nature and sweet in taste. It has the functions of strengthening the spleen and promoting diuresis, clearing away heat and draining pus. It mainly contains protein, fat, sugar, 8 essential amino acids for the human body, linoleic acid, coix seed blood lipids, coix seed extract, polysaccharides, B vitamins V, calcium, iron, Zinc and other trace elements; Modern medical research and believe that coix seed has the effects of lowering blood lipids, lowering blood sugar, laxative, weight loss, anti-fatigue, etc.; Bitter melon extract: Bitter melon is a flowering vine plant of the Cucurbitaceae family. The fruit tastes bitter and is usually used in cooking. Studies have found that bitter melon extract can significantly reduce the blood sugar level of rats with adrenaline hyperglycemia, significantly reduce the blood sugar level and MDA content of rats with alloxan hyperglycemia, increase SOD content and insulin level, and has the effect of lowering blood sugar and lipids in hyperglycemic animals. Wheat germ extract: Wheat germ, also known as malt powder, is golden granular and is one of the organs for wheat germination and growth. It accounts for about 2.5% of the total weight of the whole wheat grain. It is rich in fiber, trace elements needed by the human body, unsaturated fatty acids, vitamin E and vitamin B1, as well as oryzanol, unsaturated fatty acids, folic acid and enzymes and other nutrients. It is the part with the highest nutritional value in wheat. The extract from wheat germ can improve brain health, promote the decomposition of toxins in the body, relieve allergic reactions, and promote sugar metabolism; these plant extracts contain a variety of active ingredients, and are mixed and fermented with white kidney bean hydrolysate, trehalose, and plant extracts as fermentation substrates. The plant extracts contain a large number of active ingredients, all of which can promote the proliferation of probiotic strains and promote the fermentation process, so that a large amount of nutrients in white kidney beans are dissolved and further degraded into nutrients such as peptides, glucose, and amino acids that are easily absorbed by humans; at the same time, the plant extracts and white kidney bean hydrolysate produce a large number of beneficial nutritional molecules during mixed fermentation, which can produce a large amount of lipid-lowering substances and have a good weight loss effect.

[0026] Specifically, the present invention also discloses a method for preparing a weight-loss and lipid-lowering health product, comprising the following steps:

[0027] Step 1, mix the polypeptide and the auxiliary protective agent evenly, add water and mix evenly, wherein the amount of water added is 1-5 times the total mass of the polypeptide and the auxiliary protective agent, then add chitosan, L-carnitine tartrate, and sweetener, continue stirring for 10-20 minutes, and obtain a mixture;

[0028] Step 2, adding the filler into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 1-5 times the mass of the filler;

[0029] Step 3: Stir the mixture and the filler solution for 1-2 hours, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0030] Beneficial effects of the present invention:

[0031] (1) The present invention uses chitosan, L-carnitine tartrate, polypeptide, sweetener, auxiliary protective agent and filler as raw materials to prepare a weight loss and lipid-lowering health product, which has good weight loss and lipid-lowering performance, and at the same time, the raw material cost is low and the preparation method is simple.

[0032] (2) The present invention uses white kidney bean as raw material, and uses the interaction of endo-enzyme and exo-enzyme to enzymatically hydrolyze the white kidney bean, so that the effective active substances in the white kidney bean are effectively released, and at the same time, the amino acids, proteins and other substances in the white kidney bean are enzymatically hydrolyzed to form small molecule peptides; at the same time, the white kidney bean enzymatic hydrolyzate, trehalose and plant extract are used as fermentation substrates for mixed fermentation. The plant extract contains a large amount of active ingredients, which have the effect of promoting the proliferation of probiotic strains and promoting the fermentation process, so that a large amount of nutrients in the white kidney bean are dissolved, and further degraded into polypeptides, glucose, amino acids and other nutrients that are easily absorbed by humans; at the same time, the plant extract and the white kidney bean enzymatic hydrolyzate produce a large amount of beneficial nutritional molecules during the mixed fermentation, which can produce a large amount of lipid-lowering substances and have a good weight loss effect. DETAILED DESCRIPTION

[0033] The endpoints and any values ​​of the ranges disclosed in the present invention are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of each range, the endpoint values ​​of each range and the individual point values, and the individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be regarded as specifically disclosed in the present invention.

[0034] Introduction of some raw materials used in the embodiments of the present invention:

[0035] White kidney bean kernels, white kidney bean, its biological name is Phaseolus multiflorus, belonging to the Fabaceae, Fabaceae subfamily, Phaseolus genus, Phaseolus tribe, commercially available.

[0036] Neutral protease, product number: D832687, 50u / mg, purchased from Shanghai MacLean Biochemical Technology Co., Ltd.;

[0037] Bromelain, product number: B38620, 600u / mg, purchased from Shanghai Jizhi Biochemical Technology Co., Ltd.;

[0038] Flavor protease, product number: F861436, 20u / mg, purchased from Shanghai MacLean Biochemical Technology Co., Ltd.;

[0039] The preparation method of the hemp seed extract described in the embodiment is: take hemp seed, add water to decoct and extract 2 times, each time 8 times of water, filter, combine the water extract, condense into a clear paste with a relative density of 1.15, add 90% ethanol to adjust to an alcohol content of 60%, stir, leave standstill for 36 hours, filter, recycle ethanol in the filtrate under reduced pressure, and concentrate to a relative density of 1.2 to obtain the hemp seed extract.

[0040] The preparation method of the coix seed extract described in the embodiment is: take coix seed, add water to boil and extract twice, each time with 8 times the amount of water, filter, combine the water extract, concentrate into a clear paste with a relative density of 1.15, add 90% ethanol to adjust the alcohol content to 60%, stir, let stand for 36 hours, filter, reduce the pressure of the filtrate to recover ethanol, and concentrate to a relative density of 1.2 to obtain the coix seed extract.

[0041] Bifidobacterium bifidum, CGMCC1.5090, Latin name: Bifidobacterium bifidum, was purchased from China General Microbiological Culture Collection Center;

[0042] Lactobacillus plantarum, CGMCC1.12974, Latin name: Lactobacillus plantarum, purchased from China General Microbiological Culture Collection Center;

[0043] Aspergillus niger, CGMCC3.15663, Latin name: Aspergillus niger, purchased from China General Microbiological Culture Collection Center;

[0044] The method for preparing the probiotic strain seed liquid is as follows: the probiotic strain is inoculated into the PDA culture medium, the culture temperature is 35° C., the time is 18 hours, and the probiotic strain seed liquid is cultured respectively, and the bacterial content is 10 8 cfu / mL; the inoculation amount of the probiotic strain was 3wt%.

[0045] The preparation method of the Aspergillus niger seed liquid is as follows: inoculate the Aspergillus niger species into a PDA culture medium, culture at a temperature of 35° C. for 18 hours, and culture into Aspergillus niger seed liquids with a bacterial content of 10 8cfu / mL; the inoculation amount of Aspergillus niger was 3wt%.

[0046] Other raw materials not mentioned are common raw materials in the art. The above content is only to help illustrate the present invention and should not be construed as a strict limitation of the present invention. Those skilled in the art can directly purchase or prepare the same / similar raw materials from the market. These contents will not be repeated in the examples.

[0047] The following will be combined with the specific embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0048] Example 1

[0049] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0050] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0051] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0052] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0053] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0054] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0055] (2) adding white kidney bean protein powder and trehalose to water and mixing evenly, heating to 50° C., adding endoprotease, performing enzymolysis for 2 hours, inactivating the enzyme, filtering, and obtaining a first-grade enzymolysis solution of white kidney bean; wherein the mass ratio of white kidney bean protein powder, trehalose, and water is 1:0.8:50; the content of the endoprotease is 0.4% of the mass of the white kidney bean protein powder; wherein the endoprotease is prepared by mixing neutral protease and bromelain in a mass ratio of 1:1;

[0056] (3) adding flavor protease to the first-level enzymatic hydrolyzate of white kidney bean, heating to 45°C for enzymatic hydrolysis for 1 hour, inactivating the enzyme, filtering the supernatant, concentrating, and freeze-drying to obtain white kidney bean polypeptide; wherein the content of flavor protease is 0.3% of the mass of white kidney bean protein powder.

[0057] Comparative Example 1

[0058] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0059] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0060] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0061] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0062] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0063] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0064] (2) Add white kidney bean protein powder and trehalose to water and mix them evenly, heat to 50° C., add endoprotease, perform enzymolysis for 2 hours, inactivate the enzyme, filter and obtain the supernatant, concentrate and freeze-dry to obtain white kidney bean polypeptide; wherein the mass ratio of white kidney bean protein powder, trehalose and water is 1:0.8:50; the content of the endoprotease is 0.4% of the mass of the white kidney bean protein powder; wherein the endoprotease is prepared by mixing neutral protease and bromelain in a mass ratio of 1:1.

[0065] Comparative Example 2

[0066] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0067] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0068] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0069] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0070] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0071] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0072] (2) Add white kidney bean protein powder to water and mix evenly, heat to 45° C., add flavor protease, perform enzymolysis for 1 hour, inactivate the enzyme, filter out the supernatant, concentrate, and freeze-dry to obtain white kidney bean polypeptide; wherein the mass ratio of white kidney bean protein powder to water is 1:50; and the content of flavor protease is 0.3% of the mass of white kidney bean protein powder.

[0073] Example 2

[0074] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0075] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0076] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0077] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0078] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0079] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0080] (2) adding white kidney bean protein powder and trehalose to water and mixing them evenly, then inoculating probiotic bacteria seed liquid, fermenting and culturing at 38° C. for 12 hours, and sterilizing after the fermentation to obtain a white kidney bean primary fermentation product; wherein the mass ratio of white kidney bean protein powder, trehalose, and water is 1:0.8:50; the inoculation amount of the probiotic bacteria seed liquid is 5wt%; the probiotics are prepared by mixing Bifidobacterium bifidum and Lactobacillus plantarum in a mass ratio of 1:2;

[0081] (3) Inoculating the Aspergillus niger seed liquid into the above-mentioned white kidney bean primary fermentation product, fermenting at 38° C. for 12 h, sterilizing and filtering the supernatant after the fermentation, concentrating and freeze-drying to obtain white kidney bean polypeptide; wherein the inoculation amount of the Aspergillus niger seed liquid is 3 wt %.

[0082] Comparative Example 3

[0083] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0084] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0085] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0086] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0087] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0088] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0089] (2) Add white kidney bean protein powder and trehalose to water and mix them evenly, then inoculate probiotic seed liquid, ferment and culture at 38° C. for 12 hours, sterilize and filter the supernatant after fermentation, concentrate and freeze-dry to obtain white kidney bean polypeptide; wherein the mass ratio of white kidney bean protein powder, trehalose and water is 1:0.8:50; the inoculation amount of the probiotic seed liquid is 5wt%; the probiotics are mixed with Bifidobacterium bifidum and Lactobacillus plantarum in a mass ratio of 1:2.

[0090] Comparative Example 4

[0091] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0092] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0093] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0094] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0095] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0096] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0097] (2) Add white kidney bean protein powder and trehalose to water and mix them evenly, then inoculate Aspergillus niger seed liquid, ferment and culture at 38° C. for 12 hours, sterilize and filter the supernatant after the fermentation, concentrate and freeze-dry to obtain white kidney bean polypeptide; wherein the mass ratio of white kidney bean protein powder, trehalose and water is 1:0.8:50; and the inoculation amount of the blackberry fungus seed liquid is 3wt%.

[0098] Example 3

[0099] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0100] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0101] Step 2, mix the white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0102] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0103] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0104] The preparation method of white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging, removing the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0105] (2) adding white kidney bean protein powder and trehalose to water and mixing evenly, heating to 50° C., adding endoprotease, performing enzymolysis for 2 hours, inactivating the enzyme, filtering, and obtaining a first-grade enzymolysis solution of white kidney bean; wherein the mass ratio of white kidney bean protein powder, trehalose, and water is 1:0.8:50; the content of the endoprotease is 0.4% of the mass of the white kidney bean protein powder; wherein the endoprotease is prepared by mixing neutral protease and bromelain in a mass ratio of 1:1;

[0106] (3) adding flavor protease to the first enzymatic hydrolysate of white kidney bean, heating to 45° C. for 1 hour, inactivating the enzyme, filtering, and obtaining a second enzymatic hydrolysate of white kidney bean; wherein the content of flavor protease is 0.3% of the mass of the white kidney bean protein powder;

[0107] (4) adding trehalose to the secondary enzymatic hydrolysate of white kidney bean and mixing evenly, then inoculating the probiotic bacteria seed solution, fermenting and culturing at 38° C. for 12 hours, and sterilizing after the fermentation to obtain a primary fermentation product of white kidney bean; wherein the trehalose content is 5% of the mass of the secondary enzymatic hydrolysate of white kidney bean; the inoculation amount of the probiotic bacteria seed solution is 5wt%; the probiotics are mixed with Bifidobacterium bifidum and Lactobacillus plantarum in a mass ratio of 1:2;

[0108] (5) Inoculating the Aspergillus niger seed liquid into the above-mentioned white kidney bean primary fermentation product, fermenting at 38° C. for 12 h, sterilizing and filtering the supernatant after the fermentation, concentrating and freeze-drying to obtain white kidney bean polypeptide; wherein the inoculation amount of the Aspergillus niger seed liquid is 3 wt %.

[0109] Example 4

[0110] A method for preparing a weight-loss and lipid-lowering health product comprises the following steps:

[0111] Step 1: weigh 5 parts by weight of chitosan, 6 parts by weight of L-carnitine tartrate, 12 parts by weight of functionalized white kidney bean polypeptide, 4 parts by weight of erythritol, 9 parts by weight of lecithin, and 20 parts by weight of filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1);

[0112] Step 2, mix the functionalized white kidney bean polypeptide and lecithin evenly, add water and mix evenly, wherein the amount of water added is 3 times the total mass of the polypeptide and lecithin, then add chitosan, L-carnitine tartrate, and erythritol, continue stirring for 20 minutes, and obtain a mixture;

[0113] Step 3, adding a filler (hydroxyethyl cellulose and alginate in a mass ratio of 1:1) into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 3 times the mass of the filler;

[0114] Step 4: Stir the mixture and the filler solution for 1 hour, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

[0115] The preparation method of the functionalized white kidney bean polypeptide is as follows: (1) soaking and peeling white kidney bean kernels, homogenizing for 20 minutes, adjusting the pH to 8, subjecting to ultrasonic treatment (15kHz, 200W) for 60 minutes, soaking overnight and centrifuging to remove the oil layer and the lower precipitate, adjusting the pH to 5, stirring for 30 minutes and then centrifuging, taking the precipitate and washing it with water until it is neutral, and drying it to obtain white kidney bean protein powder;

[0116] (2) adding white kidney bean protein powder and trehalose to water and mixing evenly, heating to 50° C., adding endoprotease, performing enzymolysis for 2 hours, inactivating the enzyme, filtering, and obtaining a first-grade enzymolysis solution of white kidney bean; wherein the mass ratio of white kidney bean protein powder, trehalose, and water is 1:0.8:50; the content of the endoprotease is 0.4% of the mass of the white kidney bean protein powder; wherein the endoprotease is prepared by mixing neutral protease and bromelain in a mass ratio of 1:1;

[0117] (3) adding flavor protease to the first enzymatic hydrolysate of white kidney bean, heating to 45° C. for 1 hour, inactivating the enzyme, filtering, and obtaining a second enzymatic hydrolysate of white kidney bean; wherein the content of flavor protease is 0.3% of the mass of the white kidney bean protein powder;

[0118] (4) Add plant extract and trehalose to the secondary enzymatic hydrolysate of white kidney bean and mix them evenly, then inoculate the probiotic strain seed solution, ferment and culture at 38°C for 12 hours, sterilize after the fermentation, and obtain the primary fermentation product of white kidney bean; wherein the content of plant extract is 6% of the mass of the secondary enzymatic hydrolysate of white kidney bean; the content of trehalose is 5% of the mass of the secondary enzymatic hydrolysate of white kidney bean; the inoculation amount of the probiotic strain seed solution is 5wt%; the probiotics are prepared by mixing Bifidobacterium bifidum and Lactobacillus plantarum in a mass ratio of 1:2; the plant extract is prepared by mixing hemp seed extract and coix seed extract in a mass ratio of 2:1.

[0119] (5) Inoculating the Aspergillus niger seed liquid into the above-mentioned white kidney bean primary fermentation product, fermenting at 38° C. for 12 h, sterilizing and filtering the supernatant after the fermentation, concentrating and freeze-drying to obtain a functionalized white kidney bean polypeptide; wherein the inoculation amount of the Aspergillus niger seed liquid is 3 wt %.

[0120] Example 5

[0121] The method is basically the same as Example 4, except that the plant extract used is hemp seed extract.

[0122] Example 6

[0123] The method is basically the same as Example 4, except that the plant extract used is coix seed extract.

[0124] Test Example 1

[0125] 120 SPF male C57 mice of equivalent weight were selected, and the experiment was started after 7 days of adaptive feeding. The mice were evenly divided into 12 groups (blank control group, obesity model group, embodiment 1-6 and comparative example 1-4), 10 in each group; the blank control group was fed with ordinary feed, and the remaining groups of mice were fed with high-fat feed, and were fed continuously for 30 days to establish a nutritional obesity model. After successful modeling, each component was given an equal amount of health products of embodiment 1-6 and comparative example 1-4 from the 31st day, and the medicinal liquid of 10mg / mL was configured with normal saline, and 10mL / kg.BW was gavaged every day, and the blank control group and the obesity model group were gavaged with the corresponding volume of normal saline. During this period, each group was quantitatively fed, and the blank control group continued to feed ordinary feed, and the others continued to feed high-fat feed. The weight and food intake of mice were recorded every day since the administration, and the weight mean value of different time stages was calculated to the 6th week, and the statistical weight gain rate and food intake inhibition rate after the experiment were recorded.

[0126] Table 1 Test results of weight gain rate and food intake suppression rate of weight loss and lipid-lowering health products

[0127]

[0128]

[0129] Six weeks after the experiment, the mice were weighed 12 hours after the last intragastric administration. After the experiment, the mice were fasted for 12 hours and blood was collected from the orbits to measure the levels of triglyceride and cholesterol in the serum.

[0130] Table 2 Test results of triglyceride and cholesterol of weight loss and lipid-lowering health products

[0131]

[0132]

[0133] The invention uses chitosan, L-carnitine tartrate, polypeptide, sweetener, auxiliary protective agent and filler as raw materials to prepare the weight-loss and lipid-lowering health care product, which has good weight-loss and lipid-lowering performances, and has low raw material cost and simple preparation method.

[0134] The present application uses white kidney bean as raw material, and adopts the interaction of endo-nuclease and exo-nuclease to enzymolyze the white kidney bean, so that the effective active substances in the white kidney bean are effectively released, and at the same time, the amino acids, proteins and other substances in the white kidney bean are enzymolyzed to form small molecule peptides; at the same time, white kidney bean enzymolyzate, trehalose and plant extract are used as fermentation substrates for mixed fermentation. The plant extract contains a large number of active ingredients, which have the effect of promoting the proliferation of probiotic strains and promoting the fermentation, so that the nutrients in the white kidney bean are dissolved in large quantities and further degraded into nutrients such as polypeptides, glucose and amino acids that are easily absorbed by humans; at the same time, the plant extract and the white kidney bean enzymolyzate produce a large number of beneficial nutritional molecules during the mixed fermentation, which can produce a large number of lipid-lowering substances and have a good weight loss effect.

[0135] The performance of Example 1 is better than that of Comparative Examples 1-2. The possible reason is that the white kidney bean protein powder is hydrolyzed for the first time by endoprotease and then hydrolyzed for the second time by flavor protease. The two interact with each other to form a polypeptide with a smaller molecular weight, thereby increasing the yield of the polypeptide and making it easier to be absorbed by the human body.

[0136] The performance of Example 4 is better, and the possible reason is that the present application uses the second enzymolysis liquid as the fermentation base, and adds plant extracts at the same time, which provides a carbon source for probiotics while promoting the proliferation of probiotics, shortening the fermentation time and increasing the fermentation efficiency; Hemp seed, also known as cannabis seed, is the dried mature seed of the Moraceae plant hemp (Cannabis sativa L.), and is a traditional Chinese medicine with a long history of medicinal use. Hemp seed contains a large amount of unsaturated fatty acids, which has the effect of regulating blood lipids. Hemp seed is rich in protein, with a content of about 20%, and the essential amino acid arginine content is extremely high. Hemp seed protein is very easy to digest, and its digestibility reaches 88%-91%, which is significantly higher than soy protein (71%), and has excellent balanced nutrition and the effect of improving physical fitness. Studies have found that after hemp seed protein is degraded by enzymes and fermentation, it can generate polypeptide substances with lipid-lowering and antioxidant activities. At the same time, hemp seed extract has a proliferation effect on Bifidobacterium bifidum and Lactobacillus plantarum. Job's tears seed extract is the seed kernel of the annual and perennial herbaceous plant Job's tears seed; it is flat in nature and sweet in taste; it has the functions of strengthening the spleen and promoting diuresis, clearing away heat and draining pus; it mainly contains protein, fat, sugar, 8 kinds of essential amino acids for the human body, linoleic acid, coix seed blood lipids, coixol, polysaccharides, B group V, calcium, iron, zinc and other trace elements; modern medical research and believe that Job's tears have the effects of lowering blood lipids, lowering blood sugar, It has laxative, weight loss, anti-fatigue and other effects; these plant extracts contain a variety of active ingredients, and are mixed and fermented with white kidney bean hydrolysate, trehalose, and plant extracts as fermentation substrates. The plant extracts contain a large number of active ingredients, which can promote the proliferation of probiotics and promote the fermentation process, so that a large amount of nutrients in white kidney beans are dissolved, and further degraded into nutrients such as peptides, glucose, and amino acids that are easily absorbed by humans; at the same time, plant extracts and white kidney bean hydrolysate produce a large number of beneficial nutritional molecules during mixed fermentation, which can produce a large amount of lipid-lowering substances and have a good weight loss effect.

[0137] Test Example 2

[0138] The white kidney bean polypeptide or functionalized white kidney bean polypeptide prepared in the examples and comparative examples was made into a 10 mg / mL sample solution, 1 mL of the sample solution was mixed with 4 mL of 0.12 mmol / L DPPH solution (prepared with anhydrous ethanol), and the absorbance was detected at a wavelength of 517 nm after standing in a sealed container for 30 minutes at room temperature. The control group was a 10 mg / mL vitamin C solution, and the clearance rate was calculated as follows:

[0139] DPPH clearance rate (%) = [1-(A1-A2) / A0] × 100%

[0140] In the formula, A1 is the absorbance value of the reaction between the sample and DPPH;

[0141] A2 is the absorbance value of the sample replaced by ethanol;

[0142] A0 is the absorbance of distilled water instead of the sample.

[0143] Table 3 Antioxidant performance test results of weight loss and lipid-lowering health products

[0144]

[0145]

[0146] The present application uses white kidney bean as raw material, and adopts the interaction of endo-nuclease and exo-nuclease to enzymolyze the white kidney bean, so that the effective active substances in the white kidney bean are effectively released, and at the same time, the amino acids, proteins and other substances in the white kidney bean are enzymolyzed to form small molecule peptides; at the same time, white kidney bean enzymolyzate, trehalose and plant extract are used as fermentation substrates for mixed fermentation. The plant extract contains a large number of active ingredients, which have the effect of promoting the proliferation of probiotic strains and promoting the fermentation, so that the nutrients in the white kidney bean are dissolved in large quantities and further degraded into nutrients such as polypeptides, glucose and amino acids that are easily absorbed by humans; at the same time, the plant extract and the white kidney bean enzymolyzate produce a large number of beneficial nutritional molecules during the mixed fermentation, which can produce a large number of lipid-lowering substances, and at the same time have a good weight loss effect and good antioxidant properties.

[0147] The preferred specific embodiments of the present invention are described in detail above. It should be understood that a person skilled in the art can make many modifications and changes based on the concept of the present invention without creative work. Therefore, any technical solution that can be obtained by a person skilled in the art through logical analysis, reasoning or limited experiments based on the concept of the present invention on the basis of the prior art should be within the scope of protection determined by the claims.

Claims

1. A health product for reducing weight and lowering blood lipids, characterized in that: The invention comprises the following raw materials: chitosan, L-carnitine tartrate, polypeptide, sweetener, auxiliary protective agent and filler.

2. The weight loss and lipid-lowering health product according to claim 1, characterized in that: The invention comprises the following raw materials: 1-5 parts by weight of chitosan, 1-6 parts by weight of L-carnitine tartrate, 10-15 parts by weight of polypeptide, 1-5 parts by weight of sweetener, 5-12 parts by weight of auxiliary protective agent and 15-25 parts by weight of filler.

3. The weight loss and lipid-lowering health product according to claim 1 or 2, characterized in that: The sweetener is at least one of fructose, glucose, galactose, erythritol, maltitol and sorbitol.

4. The weight loss and lipid-lowering health product according to claim 1 or 2, characterized in that: The auxiliary protective agent is at least one of lecithin and coconut oil.

5. The weight loss and lipid-lowering health product according to claim 1 or 2, characterized in that: The filler is at least one of hydroxyethyl cellulose, gum arabic, alginate, microcrystalline cellulose and pregelatinized starch.

6. The weight loss and lipid-lowering health product according to claim 1 or 2, characterized in that: The polypeptide is a white kidney bean polypeptide or a functionalized white kidney bean polypeptide.

7. The health product for reducing weight and lowering blood lipids according to claim 6, characterized in that: The preparation method of the functionalized white kidney bean polypeptide comprises: (1) soaking white kidney bean kernels, peeling, homogenizing, adjusting pH, ultrasonic treatment, soaking overnight and then centrifuging, removing the oil layer and the lower precipitate, adjusting pH, stirring and then standing and centrifuging, taking the precipitate and washing it with water until it is neutral, and drying to obtain white kidney bean protein powder; (2) adding white kidney bean protein powder and trehalose into water and mixing evenly, heating, adding endoprotease, enzymolysis, inactivating enzyme, filtering, and obtaining a first-level enzymolysis solution of white kidney bean; (3) adding flavor protease to the first enzymatic hydrolyzate of white kidney bean, heating for enzymatic hydrolysis, inactivating the enzyme, filtering, and obtaining a second enzymatic hydrolyzate of white kidney bean; (4) adding the plant extract and trehalose to the white kidney bean secondary enzymatic hydrolysate and mixing them evenly, then inoculating the probiotic bacteria seed solution, fermenting and culturing, and sterilizing after the fermentation is completed to obtain the white kidney bean primary fermentation product; (5) inoculating the Aspergillus niger seed liquid into the above-mentioned white kidney bean primary fermentation product, fermenting, sterilizing, filtering and obtaining the supernatant after the fermentation is completed, concentrating and freeze-drying to obtain the functionalized white kidney bean polypeptide.

8. The health product for reducing weight and lowering blood lipids according to claim 7, characterized in that: The endoprotease is at least one of alkaline protease, neutral protease and bromelain.

9. The weight loss and lipid-lowering health product according to claim 7, characterized in that: The probiotics are at least one of Bifidobacterium bifidum and Lactobacillus plantarum.

10. The method for preparing the weight-loss and lipid-lowering health product according to any one of claims 1 to 9, characterized in that: The following steps are involved: Step 1, mix the polypeptide and the auxiliary protective agent evenly, add water and mix evenly, wherein the amount of water added is 1-5 times the total mass of the polypeptide and the auxiliary protective agent, then add chitosan, L-carnitine tartrate, and sweetener, continue stirring for 10-20 minutes, and obtain a mixture; Step 2, adding the filler into water and mixing evenly to obtain a filler solution, wherein the amount of water added is 1-5 times the mass of the filler; Step 3: Stir the mixture and the filler solution for 1-2 hours, then add them into an extrusion microcapsule granulator for extrusion granulation, and finally freeze-dry the obtained particles.

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