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Lamiophlomis rotata cataplasm and preparation method thereof

A unique and cataplasmic technology, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., can solve the problems of long disintegration time, low bioavailability, and poor stability of oral sugar-coated tablets , to achieve good moisturizing properties, less skin irritation, and good drug compatibility

Inactive Publication Date: 2010-01-06
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the above-mentioned products also have some problems, such as low bioavailability, poor stability, long disintegration time of oral sugar-coated tablets, slow dissolution, large dosage and other shortcomings

Method used

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  • Lamiophlomis rotata cataplasm and preparation method thereof
  • Lamiophlomis rotata cataplasm and preparation method thereof
  • Lamiophlomis rotata cataplasm and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Prepare Duyiwei Qing Gao as follows:

[0027] Weigh a sufficient amount of unique herbal medicine, coarsely crush it, add water to decoct three times, add water respectively 10 times, 8 times, and 8 times, each time for one hour, and combine to obtain a medicinal solution; filter the obtained medicinal solution, and the filtrate is under normal pressure When concentrated to 50°C, a clear paste with a relative density of 1.30 was obtained.

[0028] Then prepare the matrix as follows:

[0029] Add 8 to 16 parts of water to gelatin, stir and dissolve at 50°C, add 10 parts of zinc oxide to obtain component 1.

[0030] Disperse 8 parts of sodium polyacrylate in 15 parts of sorbitol and 5 parts of propylene glycol, add 20 parts of water to dissolve into a clear colloidal solution, and obtain component 2.

[0031] Take 2 parts of polyvinyl alcohol and add 15 parts of water, heat to 70°C, stir to dissolve, then add 3 parts of sodium carboxymethyl cellulose, stir evenly to obt...

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PUM

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Abstract

The invention relates to lamiophlomis rotata cataplasm and a preparation method thereof. The cataplasm comprises lamiophlomis rotata extracts, appropriate matrix and auxiliary materials. The lamiophlomis rotata cataplasm has excellent therapeutic effects of clearing heat, eliminating tumescence, activating blood circulation and relieving pain without causing any adverse reaction.

Description

technical field [0001] The invention relates to a unique cataplasm and a preparation method thereof. The preparation can be used for preventing and treating incision pain, bleeding, trauma fracture, soft tissue contusion, rheumatic arthralgia, cervical spondylosis and the like in various surgical operations. Background technique [0002] Lamiophlomis rotata (Benthl) Kudo is a plant of the genus Lamiophlomis rotata (Benthl). There is only one species of this genus. It is also known as Dubutong. It is called "Daba" and "Dabuba" in Tibetan. It grows on gravel beaches above 3000m above sea level. Among them, they are distributed in Gansu, Qinghai, Sichuan, Yunnan, Tibet and other places. Its root and whole herb are used as medicine, and it is one of the commonly used folk medicines of Tibetan, Mongolian, Naxi and other ethnic groups in my country. It has analgesic, anti-inflammatory, hemostatic, antibacterial, immune-enhancing, anti-tumor effects. Orally administered to mice, ...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K9/70A61K47/42A61K47/46A61P29/00A61P19/08A61P7/04
Inventor 李馨儒刘艳
Owner PEKING UNIV
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