74results about How to "Suitable for industrialization" patented technology

The invention discloses a plant leaf biomimetic material with antifouling, self-cleaning and spectrum simulation properties and a preparation method thereof. The plant leaf biomimetic material sequentially comprises a first liquid injection super-smooth porous elastomer layer, a hydrogel layer, a camouflage yarn-dyed fabric layer, a hydrogel layer and a second liquid injection super-smooth porous elastomer layer from bottom to top, the liquid injection super-lubricity porous elastomer layer is a porous elastomer of which gaps are filled with silicone oil; the first and second liquid injection super-lubricity elastomer layers are made of the same or different materials; the hydrogel layer is one of single-network hydrogel or double-network hydrogel; and the color of the disguise yarn-dyed fabric layer is one of dark green, medium green, yellow green and light green. The plant leaf biomimetic material disclosed by the invention is excellent in plant leaf spectrum simulation effect, can simulate cell tissues of plants, has anti-mud and hydrophobic properties, can still keep the excellent plant leaf spectrum simulation effect after being washed by rainwater, and can realize high-weather-resistance spectrum simulation.

The invention discloses an anti-hair-loss composition, preparation thereof and application of the anti-hair-loss composition in hair washing and caring products, and belongs to the field of cosmetic preparation. The method for preparing the anti-hair-loss composition with the good and lasting anti-hair-loss effect comprises the following steps: (1) uniformly mixing arginine and citric acid, then adding diaminopyrimidine oxide, and continuously and uniformly mixing to form a mixture A; (2) uniformly mixing azelaic acid, nicotinamide and butanediol to form a mixture B; (3) uniformly mixing the mixture A, the mixture B, caffeine, a sanguisorba officinalis root extract, a green tea extract and a cacumen biotae extract to obtain the anti-hair loss composition. The anti-hair loss composition prepared by the invention is simple in component and simple in preparation process; the effect is lasting, and the anti-hair loss effect is good.

The invention belongs to the technical field of composite materials, and particularly relates to a carbon fiber composite material for preventing low-temperature medium leakage and a preparation method and application thereof. The carbon fiber composite material comprises carbon fibers, a resin matrix, modified nano-hydroxyapatite and an anti-seepage film, the mass percentage content of the carbon fiber is 45-69%, the mass percentage content of the resin matrix is 26-37%, the mass percentage content of the impermeable film is 2-10%, and the balance is modified nano-hydroxyapatite; the modified nano-hydroxyapatite, the impermeable film and other raw materials are added into the formula of the carbon fiber composite material, and the impermeable performance of the carbon fiber composite material in a low-temperature medium is comprehensively improved through the modified nano-hydroxyapatite and the impermeable film. Experimental results show that the thickness of the carbon fiber composite material is smaller than 3 mm, and the leakage rate under 3 MPa is smaller than 10 <-5 > Pa.m < 3 > / s.

The invention discloses a soluble expression and purification method of recombinant human bone morphogenetic protein in a prokaryotic system. A gene sequence of a recombinant human bone morphogenetic protein (rhBMP) is spliced at the 3'terminal of a His-Linker-GB1 gene sequence, inserted into a prokaryotic expression system expression vector and transferred into a prokaryotic competent cell to be highly expressed in the cell in a soluble form, and finally, the expressed His-Linker-GB1-BMP fusion protein does not need to be subjected to inclusion body renaturation, so that the recombinant human bone morphogenetic protein (rhBMP) is obtained. The high-purity fusion protein can be obtained through one-step metal chelating chromatography (adsorption-elution mode), and the GB1 tag has small molecular weight and hardly affects the spatial structure and biological activity of rhBMP, so that the situation that an inclusion body is formed by expression of rhBMP in a traditional escherichia coli system and expression is performed in a structure-free and activity-free inclusion body form is avoided, and the expression efficiency is greatly improved. The method is simple and convenient to operate, is suitable for large-scale amplification, and has the characteristics of short period, high purity, stable process and the like.

The invention relates to the technical field of selective impurity removal of valuable elements in acid solutions, in particular to a method for selective iron removal of rare earth pickle liquor. The method comprises the following specific steps: firstly, taking pickle liquor generated in an industrial production process, adding a first medicament, and stirring for pretreatment; adding a second medicament into the pretreated solution, and stirring to selectively remove iron; finally, a coagulant is added for solid-liquid separation, and supernate and iron-containing sediment are obtained. The total iron content in the supernate is lower than 5.0 mg / L, so that the production requirements of enterprises are met. The method has the advantages of simple and easy process, low equipment requirement, convenience in operation, wide application range and the like, and has good social benefits and economic values.

The invention relates to the technical field of preparation of microcrystalline glass, in particular to lithium metasilicate microcrystalline glass and a preparation method thereof, the lithium metasilicate microcrystalline glass comprises the following components in percentage by mass: 62%-78% of SiO2, 3%-10% of Al2O3, 4%-18% of Li2O, 0-5% of K2O, 0.6%-7.5% of P2O5 and 2%-15% of ZrO2, the value of (SiO2 + Al2O3) / Li2O) is 6-15, the value of Al2O3 / Li2O is 0.7-1.3, and P2O5 + ZrO2 is less than 8%. According to the technical scheme, by designing a proper basic glass material formula, a heat treatment crystallization process system and a chemical strengthening process, the high-strength transparent glass ceramic with lithium metasilicate as a main crystal phase is obtained; the glass has the characteristics of large surface compressive stress, high strength, strong ion exchange capacity, excellent impact resistance, excellent falling resistance and the like, so that the application requirement of the glass as a cover plate on an electronic product is met. The problems that in the prior art, glass ceramics are insufficient in strength and transparency and cannot meet the requirements of electronic device protection glass cover plates are solved.

The invention provides a yellow long-afterglow ceramic low-temperature overglaze color pigment as well as a preparation method and application thereof, and belongs to the technical field of ceramic pigments. Noctilucent powder SrAl2O4: Eu < 2 + > and Dy < 3 + > and fluorescent powder Y3Al5O12: Ce < 3 + > or Y3Al5O12: Ce < 3 + > and Gd < 3 + > are combined according to different proportions to form a yellow long-afterglow luminescent pigment, then the yellow long-afterglow luminescent pigment is mixed with a glaze surface combination auxiliary agent, and the low-temperature overglaze color pigment with yellow long-afterglow emission is obtained by utilizing a new principle and technology of energy transfer and reflection-compensation, can be fired on a glaze surface at a relatively low temperature, and has the characteristics of long-afterglow emission and long-afterglow emission. Bright yellow body color is displayed under sunlight or an artificial light source; in the dark, afterglow emission which is adjustable from yellow green to yellow is shown. The yellow long-afterglow ceramic low-temperature overglaze color pigment provided by the invention can improve the unique decorative effect of porcelain, enrich the color of the porcelain and improve the added value of ceramic products, and is a novel luminous pigment with excellent performance.

The invention relates to the technical field of preparation of new energy battery positive electrode material precursors, in particular to a ferromanganese oxalate precursor, a preparation method and a lithium manganese iron phosphate positive electrode material.The method comprises the steps that a solution A is prepared from water, ferric salt, manganese salt, metal M salt and an antioxidant; then, preparing a solution B from water, ammonium oxalate and an antioxidant; and finally, under the protection of inert gas, dropwise adding the solution B into the solution A to obtain the oxalate ferromanganese precursor. According to the method, the alpha-crystal-form ferromanganese oxalate is successfully synthesized, the yield of the beta-crystal-form ferromanganese oxalate in the synthesis process is greatly reduced, the ferromanganese and the ferromanganese can be mixed at the atomic level, and the dissolution of manganese and the Jahn-Teller effect are inhibited; in-situ metal element doping improves the electronic conductivity of the material; the problems that an existing lithium iron manganese phosphate positive electrode material prepared from ferromanganese oxalate is poor in electronic conductivity and electrochemical performance and cannot meet the use requirement of a lithium ion battery are solved.

The invention discloses a method for separating and purifying squalene from squalene fermentation liquor, and belongs to the technical field of squalene extraction. The method comprises the following steps: 1) pretreatment: adding a wall breaking reagent into squalene fermentation liquor for wall breaking, or concentrating the squalene fermentation liquor and then adding the wall breaking reagent for wall breaking; 2) extraction: adding an organic solvent and a demulsifier, layering to obtain a water phase and an organic phase, and collecting the organic phase; 3) impurity removal: adding an aqueous solution, layering to obtain an aqueous phase and an organic phase, and collecting the organic phase; and 4) distilling: distilling to obtain purified squalene. The method is simple to operate, low in equipment investment, simple in post-treatment and low in extraction cost, and the obtained squalene refined product is high in yield, high in purity and suitable for industrialization.

The invention belongs to the technical field of batteries, and particularly discloses a positive electrode material and a preparation method thereof, a lithium ion battery and a power utilization device, the positive electrode material comprises lithium manganese iron phosphate, the unit cell volume of the lithium manganese iron phosphate is # imgabs0 #, the positive electrode material has high compaction density, electronic conductivity and ionic conductivity, and the lithium ion battery can be used as a lithium ion battery. By adopting the positive electrode material, the energy density and the cycling stability of the battery containing the positive electrode material can be improved.

The invention discloses a method for synthesizing 3-(2-hydroperoxy-2-propyl) phenol and a preparation method of the 3-(2-hydroperoxy-2-propyl) phenol. The method comprises the following steps: in the presence of a solvent, 1, 3-bis (2-hydroperoxy-2-propyl) benzene is in contact with a potassium hydrogen sulfate catalyst for an acidolysis reaction, 3-(2-hydroperoxy-2-propyl) phenol is obtained, and the weight ratio of the 1, 3-bis (2-hydroperoxy-2-propyl) benzene to the catalyst is (15-48): 1. According to the method provided by the invention, 1, 3-bis (2-hydroperoxy-2-propyl) benzene (m-DHP) is used as a raw material, and a selective acidolysis reaction is carried out in the presence of a solid potassium hydrogen sulfate catalyst to obtain 3-(2-hydroperoxy-2-propyl) phenol m-HPP. The method has the characteristics of high yield, cleanness, environment friendliness, mild reaction conditions and easiness in industrialization.

The invention discloses a biaryl compound with necroptosis resisting activity as well as a derivative and application of the biaryl compound. The biaryl compound is a compound as shown in # imgabs0 # or a pharmaceutically acceptable salt of the biaryl compound. The synthesis method of the compound is simple, and the obtained compound can inhibit in-vitro necrotic apoptosis of HT-29 cells and can relieve hepatic fibrosis progress of a schistosome infected mouse model. The compound can be used for preparing drugs for treating and / or preventing inflammatory, fibrosis, infectious, ischemic, degenerative or tumor diseases caused by necrotic apoptosis, and has a good market prospect.

The invention discloses a preparation method of 3-amino-2-fluorobenzoyl chloride and a derivative thereof (a formula A-V or a formula B-VI), wherein the formula A-V can adopt the following synthetic route: a route I: # imgabs0 # or a route II: # imgabs1 # and the formula B-VI can adopt the following synthetic route: a route a: # imgabs2 # or a route b: # imgabs3 #, and R, R1, R2, R3, R4, R5 and R6 are defined in the specification. Compared with the prior art, the process route of the preparation method has more competitive advantages.

This application relates to the field of organosilicon polymer materials, specifically disclosing a method for preparing and applying a functionalized MQ silicone resin. A method for preparing a functionalized MQ silicone resin includes the following steps: (1) raw material pretreatment; (2) simultaneous addition reaction: mixing and reacting a hydrogen-containing MQ silicone resin, a terminal olefin monomer containing a benzocyclobutene functional group, and a terminal olefin monomer containing a C-F bond; (3) post-treatment to obtain the functionalized MQ silicone resin; wherein the molar ratio of Si-H bonds in the hydrogen-containing MQ silicone resin, C=C bonds in the terminal olefin monomer containing a benzocyclobutene functional group, and C=C bonds in the terminal olefin monomer containing a C-F bond is 1:(0.2-0.6):(0.1-0.4). This application enables the synergistic effect of the rigid benzocyclobutene group and the fluorinated flexible segment, one-step grafting, and structural controllability, ultimately preparing a functionalized MQ silicone resin with excellent dielectric properties, high temperature resistance, low-temperature flexibility, good hydrophobicity, and excellent mechanical strength.

The invention discloses a transmission-type laser lighting system with high front light efficiency. The transmission-type laser lighting system comprises a light shaping element, a Ce: LuAG ceramic rod, silica gel, a connecting element, a tail fiber laser and a radiator, the Ce: LuAG ceramic rod is connected with the light shaping element through silica gel, the tail fiber laser is connected with the light shaping element through the connecting element, and the radiator is located at the bottom of the tail fiber laser. The illumination system designed by the invention is high in blue light resistance power; the light source is high in luminous efficiency and high in integration level; the process is simple and suitable for industrialization.

The invention provides a separation and purification method of mangiferin monomers in aquilaria sinensis leaves, and relates to the technical field of processing and extraction of traditional Chinese medicinal materials. The method for separating and purifying the mangiferin monomer in the aquilaria sinensis leaves comprises the following steps: step 1, pretreating bay leaves; step 2, extracting and concentrating; step 3, extracting and concentrating; step 4, storing at low temperature; and step 5, washing and suction filtration. The method comprises the steps of aquilaria sinensis leaf raw material pretreatment, extraction, concentration, extraction, concentration, low-temperature storage, pure water washing and suction filtration, and finally high-purity mangiferin is obtained, the separation and purification method is simpler, the process is green and environmentally friendly, the cost is low, the product quality is good, the method is suitable for industrial and large-scale production, aquilaria sinensis leaves are adopted as the raw material, and rich mangiferin is contained; according to the mangiferin preparation method, the mangiferin is high in purity, the variety and number of other impurity components are small, the raw material does not contain allergic components, pesticides are not used in the raw material production process, and the prepared product is high-quality and high-purity mangiferin without allergens and organic pesticide residues.

The invention relates to the technical field of glass thinning liquid recovery treatment, in particular to an adsorbent for cover plate glass thinning liquid recovery and a preparation method and application thereof.The preparation method includes the steps that activated carbon is soaked in a metal salt solution to obtain activated carbon carrying metal ions, the activated carbon carrying the metal ions is subjected to high-temperature calcination to obtain the adsorbent, and the adsorbent is placed in cover plate glass thinning waste liquid for adsorption; desorbing the adsorbent loaded with the adsorption substance to obtain a desorption material which can be directly sold as a raw material; and residual waste liquid is filtered and reused in the thinning process. The method is simple, green and environment-friendly, the adsorption process is simple, resource utilization of cover plate glass thinning waste liquid treatment is achieved, the problem of environmental pollution in the cover plate glass industry can be effectively solved, sustainable development of the cover plate glass industry is promoted, and very good economic value is achieved. The problems that in the prior art, the glass thinning liquid recovery treatment process is tedious, and the economical efficiency is poor are solved.

The invention relates to high-solid-content AlN ceramic slurry for tape casting, a substrate and a preparation method of the substrate, and belongs to the field of ceramic substrates. The ceramic slurry is prepared from the following components in percentage by mass: 60 to 68 weight percent of high-purity AlN powder, 3 to 6 weight percent of dispersing agent, 3 to 5 weight percent of binding agent, 4 to 6 weight percent of plasticizer, 3 to 6 weight percent of sintering aid and 32 to 45 weight percent of solvent, the mass ratio of the plasticizer to the binder ranges from 3: 5 to 4: 5. By regulating and controlling the proportion of the dispersing agent in the AlN ceramic slurry and the solid content of the high-purity AlN powder, the slurry has excellent flowability, dispersity and stability while maintaining high solid content, and is suitable for a tape casting process. The AlN ceramic substrate prepared through sintering is high in density and excellent in heat conductivity, and engineering application can be achieved.

The invention belongs to the field of chemical engineering, and particularly relates to a method for recycling and preparing methyl acetoacetate. The method comprises the following steps: mixing the tower kettle residual liquid of a crude product diethyl methyl ester finished product tower with methanol by taking methanol as an extracting agent, keeping the temperature, stirring, and standing for layering; and taking the upper-layer methyl diethyl ester methanol solution for rectification, and stopping discharging when the kettle temperature rises to 56-60 DEG C to finally obtain methyl diethyl ester. The content of the prepared and recovered diethyl methyl ester is 95.23 to 96.53 percent, and the molar recovery rate of the diethyl methyl ester is 82.99 to 88.21 percent through calculation. According to the method, the loss of the diethyl methyl ester is reduced, the recovery rate of the diethyl methyl ester and the quality of a finished product are improved, meanwhile, harmless treatment is carried out on the tower kettle raffinate, the environmental pollution is reduced, and the waste treatment cost is reduced for chemical enterprises.

This invention relates to the field of high-purity aluminum and aluminum alloy production technology, and particularly to a porous alumina ceramic material, its preparation method, and its application. The material comprises a composite aggregate and an organic binder, wherein the mass ratio of the composite aggregate to the organic binder is 47:3. The composite aggregate comprises 9 wt%–17 wt% inorganic binder and 83 wt%–91 wt% aggregate particles. The inorganic binder comprises: 40 wt%–50 wt% B₂O₃, 20 wt%–29 wt% Al₂O₃, 10 wt%–15 wt% SiO₂, 9.4 wt%–14.4 wt% MgO, 0–0.5 wt% Na₂O, 0–0.5 wt% K₂O, and 0–10 wt% Re₂O₃, where Re is a rare earth element. This method uses corundum or α-Al₂O₃ as a framework and rare earth composite oxides as an inorganic binder. A high-temperature reaction forms sintering necks between the aggregate particles, resulting in a porous alumina ceramic with a bimodal pore distribution. Two different pore sizes are distributed in situ on the surface of the skeleton particles and the sintered neck, achieving a dual-capture filtration effect for aluminum molten inclusions. This solves the problem that filters with large pore sizes cannot simultaneously filter small-grain-sized impurities.

The invention relates to steel and a preparation method and application thereof. The steel comprises the following chemical components in percentage by mass: 0.045% to 0.065% of C, 0.28% to 0.40% of Si, 0.60% to 0.80% of Mn, 0.072% to 0.090% of P, 0.001% to 0.010% of S, 0.25% to 0.28% of Cu, 0.32% to 0.42% of Cr, 0.015% to 0.030% of Ti, less than or equal to 0.007% of N, 0.015% to 0.050% of Als and the balance of Fe and inevitable impurities. The steel is nickel-free, low in production cost, low in yield ratio, excellent in mechanical property, good in stamping performance, good in weather resistance and high in yield, and is suitable for the weather-resistant steel for the low-yield-ratio container for stamping.

The invention relates to a preparation method of beta-methylenepyridine-2-ethyl alcohol. The preparation method comprises the following steps of: adding a catalyst, the preparation method of beta-methylenepyridine-2-ethanol takes 2-picoline as a first raw material, a formaldehyde aqueous solution or paraformaldehyde as a second raw material and urotropine as a catalyst, and comprises the following steps: (1) mixing the first raw material, the second raw material, the catalyst and water, putting the mixture into a high-pressure reaction kettle, heating to 140-160 DEG C, reacting for 18-20 hours, cooling to room temperature, filtering, washing, and drying to obtain beta-methylenepyridine-2-ethanol; a solution containing the beta-methylenepyridine-2-ethanol is obtained; and (2) rectifying the solution containing the beta-methylenepyridine-2-ethanol to obtain a product. According to the method, the urotropine is selected as the catalyst, the reaction selectivity is improved by utilizing the specific space structure and charge distribution of the urotropine, the solvent is friendly in the reaction process, the steps are simple, the beta-methylenepyridine-2-ethanol can be obtained through a one-pot method, and the method is suitable for industrialization.

The invention relates to the technical field of catalyst preparation, in particular to a supported nitrogen-containing ligand-ruthenium-based catalyst, a preparation method and application, and provides guarantee for anchoring and high dispersion of an active substance ruthenium on activated carbon by utilizing interaction force between an N-substituted imidazole compound and metal ruthenium. Due to electron transfer, a Ru-N bond is formed, a low-valence ruthenium active species is stabilized, and the adsorption capacity of the catalyst to a reactant 1-hexene is improved, so that the activity of the catalyst is remarkably improved. The N-substituted imidazole compound enables ruthenium species to be deposited on activated carbon, and loss of precious metal ruthenium is reduced. Compared with heterogeneous catalysts prepared from other noble metals, the catalyst has the characteristics of low cost and good activity, and has better economic value. The problem that the Ru-based heterogeneous catalyst is inactivated due to high-temperature agglomeration or leaching loss in the prior art is solved.

The invention provides a preparation method of a rosuvastatin calcium intermediate, and belongs to the technical field of organic synthesis. (S)-4-chloro-3-hydroxybutyronitrile is used as a raw material, and the rosuvastatin calcium intermediate 2-(4R, 6S)-2, 2-dimethyl-6-[(5-methyl-1, 3, 4-thiazole-2-sulfonyl) methyl)-1, 3-dioxane] tert-butyl acetate (YD5-2) is synthesized through the steps of upper protection, addition, deprotection, chiral reduction, upper protection, addition, oxidation and the like. According to the preparation method of the rosuvastatin calcium intermediate, raw materials are easy to obtain, reaction conditions are mild, the safety coefficient is high, operability is high, the process is simple, industrialization is easy to achieve, and the product is high in purity and stable in quality.

The present application provides a kind of herbal shoe pad and its preparation method and application, the preparation method includes the following steps: herbal raw material is crushed to obtain herbal short hair, then mixed with chemical fiber, by air laying to obtain cotton-like mixture, then the upper and lower surfaces of cotton-like mixture are attached with non-woven fabric, and the herbal shoe pad is obtained after heat bonding.The herbal shoe pad provided by the present application can make the shoe pad more environmentally friendly in an industrial mass production mode, while also achieving the use of raw herbal state to absorb foot sweat, decompose and dilute odor, achieve uniform structure, controllable thickness, wear-resistant and usable through air laying and heat bonding, and have the characteristics of original ecology, high adsorption and easy degradation.

The present invention relates to the technical field of camptothecin derivative preparation, particularly to a camptothecin derivative synthesis method, which uses 2-nitroacetophenone and isopropylamine as raw materials, and the camptothecin derivative is obtained through a Mannich reaction, a methylsulfonylation reaction, a nitro reduction reaction and a ring closing reaction. According to the synthetic method of the camptothecin derivative, the complex camptothecin derivative is split into two segments 1-(2-aminophenyl)-3-(N-isopropyl-N-methylsulfonylamino) propan-1-one and a compound V which are easy to prepare, and finally, a plurality of rings and chemical bonds are constructed simultaneously through one-step efficient ring closing reaction. The yield attenuation caused by progressive multiplication of the yield in the traditional linear synthesis is avoided, and the total yield is improved.

The invention discloses a high-fracture-toughness silicon nitride ceramic ball and a preparation method thereof, and belongs to the field of high-performance structural ceramic materials. The ceramic ball is prepared by taking high-purity alpha-SiN powder as a matrix and adopting a composite sintering aid system composed of an oxygen-free rare earth compound, aluminum nitride and beta-SiN seed crystal through an air pressure sintering process controlled by program pressure. Under the synergistic effect of the auxiliary system and a specific process, 'bimodal distribution 'beta-SiN columnar crystals and high-melting-point and high-toughness intergranular phases are generated in situ in the material, so that the fracture toughness of the material is remarkably improved on the premise of not sacrificing hardness and strength. The fracture toughness of the silicon nitride ceramic ball is up to 8.5-11.0 MPa.m / , the bending strength is 750-1050 MPa, and the silicon nitride ceramic ball is particularly suitable for precision bearings under high-speed and high-load working conditions, such as a wind power generation main shaft, an aerospace engine main shaft and the like.

The invention relates to the technical field of drug synthesis, and discloses a brivaracetam synthesis method, which comprises: (1) carrying out nitrilase catalysis on 3-cyanocapronitrile to prepare (R)-3-cyanohexanoic acid, carrying out hydrogenation catalysis to obtain (R)-3-aminomethyl hexanoic acid, and carrying out amidation to obtain a compound represented by a formula I; (2) reacting the compound as shown in the formula I with methyl-2-methyl bromobutyrate in an organic solvent in the presence of alkali to obtain a compound as shown in a formula II; and (3) carrying out ammonolysis on the compound as shown in the formula II, and separating a mixture obtained by reaction through chromatography to obtain a brivaracetam product as shown in a formula III. The brivaracetam synthesis process provided by the invention is more convenient, can reduce the cost, is environment-friendly, green and efficient, and is suitable for industrialization.

The invention discloses a composite sensing electrode and a preparation method and application thereof. The electrode comprises a basic electrode, an Al / Co-MOFs / rGO layer and a bifunctional monomer molecularly imprinted polymer film, wherein the Al / Co-MOFs / rGO layer and the bifunctional monomer molecularly imprinted polymer film cover the surface of the basic electrode. The preparation method comprises the following steps: preparing an Al / Co-MOFs / rGO suspension liquid, dripping the suspension liquid on the surface of an electrode, drying the electrode, placing the electrode in a solution containing o-phenylenediamine, dopamine and template molecules, carrying out an electropolymerization reaction, and demolding to obtain the electrode. The composite sensing electrode provided by the invention has the advantages of multiple binding sites, uniform dispersion, good conductivity, good structural stability, strong specific recognition capability and the like, can realize rapid and accurate detection of perfluorinated and polyfluoroalkyl substances, can effectively reduce false positive records existing in the detection process, and can be widely applied to detection of perfluorinated and polyfluoroalkyl substances. The method has the advantages of short detection period, high detection sensitivity, high accuracy and the like, and is high in use value and good in application prospect in the fields of environment monitoring, food safety, water quality condition diagnosis and the like.

The invention discloses a synthesis method of a compound 5-bromo-[1, 1 '-biphenyl]-3-alcohol, and belongs to the technical field of organic synthesis. The synthesis method comprises the following steps: mixing a copper catalyst, alkali, a ligand, 1-phenyl-3, 5-dibromobenzene and a solvent, and stirring to react under the protection of inert gas to obtain a reaction solution; and carrying out post-treatment to obtain the 5-bromo-[1, 1 '-biphenyl]-3-alcohol. According to the invention, the compound 1-phenyl-3, 5-dibromobenzene is used as a raw material, the target compound 5-bromine-[1, 1 '-biphenyl]-3-alcohol is obtained through a copper-catalyzed nucleophilic aromatic substitution reaction and a one-step reaction, the steps are simple and short, the reaction conditions are mild, the post-treatment and purification are simple, an expensive catalyst is not needed, and the method is a novel method for preparing the 5-bromine-[1, 1'-biphenyl]-3-alcohol. And a potential route is provided for large-scale production of 1, 1 '-biphenyl]-3-alcohol.