Lamiophlomis rotata soft capsule and preparation method thereof

A unique, soft capsule technology, applied in capsule delivery, pharmaceutical formulations, medical preparations with inactive ingredients, etc., can solve the problems not mentioned, achieve energy consumption and cost reduction, production process green environmental protection, production cycle the effect of shortening

Active Publication Date: 2014-02-05
SHIJIAZHUANG HUAXIN PHARMA
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the patent description does not mention the technical content of how to increase the content of active ingredients in th...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Lamiophlomis rotata soft capsule and preparation method thereof
  • Lamiophlomis rotata soft capsule and preparation method thereof
  • Lamiophlomis rotata soft capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 Preparation of unique soft capsules of the present invention (1000 capsules)

[0023]

[0024] Preparation:

[0025] (1) Extraction of Duyiwei extract fine powder: Take the pulverized Duyiwei medicinal material, mix it with cellulase, D-amino acid oxidase, and phospholipase, and the weight ratio of cellulase, D-amino acid oxidase, and phospholipase 5:10:1, the total weight of the three is 0.5 times the weight of the unique medicinal material, add water and decoct for 25 minutes, filter, the filtrate is concentrated at 60°C to an extract with a relative density of 1.20, and depressurized at 80°C Dried unique extract powder, set aside,

[0026] (2) Preparation of the content: Mix the fine powder of the unique extract obtained in step (1) with grape seed oil and mannitol at 50°C, and set aside;

[0027] (3) Preparation of glue solution: add gelatin to purified water, heat to 35°C, add glycerin, polyethylene glycol 400, bright black and xylitol, stir for 1...

Embodiment 2

[0029] Embodiment 2 Preparation of unique soft capsules of the present invention (1000 capsules)

[0030]

[0031] Preparation:

[0032] (1) Extraction of Duyiwei extract fine powder: Take the pulverized Duyiwei medicinal material, mix it with cellulase, D-amino acid oxidase, and phospholipase, and the weight ratio of cellulase, D-amino acid oxidase, and phospholipase 10:12:1, the total weight of the three is 0.8 times the weight of the unique medicinal material, add water and decoct for 25 minutes, filter, the filtrate is concentrated at 60°C to an extract with a relative density of 1.20, and depressurized at 80°C Dried unique extract powder, set aside,

[0033] (2) Preparation of the content: Mix the fine powder of the unique extract obtained in step (1) with grape seed oil and mannitol at 50°C, and set aside;

[0034] (3) Preparation of glue solution: add gelatin to purified water, heat to 35°C, add glycerin, polyethylene glycol 400, bright black and xylitol, stir for ...

Embodiment 3

[0036] Embodiment 3 Preparation of Duyiwei Soft Capsules of the present invention (1000 capsules)

[0037]

[0038]

[0039] Preparation:

[0040] (1) Extraction of Duyiwei extract fine powder: Take the pulverized Duyiwei medicinal material, mix it with cellulase, D-amino acid oxidase, and phospholipase, and the weight ratio of cellulase, D-amino acid oxidase, and phospholipase 8:11:1, the total weight of the three is 0.7 times the weight of the unique medicinal material, add water and decoct for 25 minutes, filter, the filtrate is concentrated at 60°C to an extract with a relative density of 1.20, and depressurized at 80°C Dried unique extract powder, set aside,

[0041] (2) Preparation of the content: Mix the fine powder of the unique extract obtained in step (1) with grape seed oil and mannitol at 50°C, and set aside;

[0042] (3) Preparation of glue solution: add gelatin to purified water, heat to 35°C, add glycerin, polyethylene glycol 400, bright black and xylitol,...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a lamiophlomis rotata capsule and a preparation method thereof, belongs to the technical field of medicines, and in particular belongs to the technical field of medicinal preparations. The lamiophlomis rotata soft capsule consists of a content and a soft capsule shell, wherein 0.063-0.078mg of rutin which contains total flavonoids with a molecular formula of C27H30O16 is contained in each mg of the content. The lamiophlomis rotata capsule has the remarkable characteristics of stable property, long storage time, short disintegration, quick dissolution and the like which are not possessed by common soft capsules.

Description

technical field [0001] The invention relates to a soft capsule preparation and a preparation method thereof, in particular to a Duyiwei soft capsule and a preparation method thereof, belonging to the technical field of medicine, in particular to the technical field of pharmaceutical preparations. Background technique [0002] Unique flavor, medicinal material, perennial herb. Bitter, slightly cold. It is slightly poisonous. It has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, and is used for bruises, fractures, and lumbar sprains. Its chemical components are luteolin (luteolin), luteolin-7-O-glucoside (luteolin-7-O-glucoside), quercetin (quercetin), quercetin-3-O-arabinoside ( quercetin-3O-glucoside), Quercetin (quercetin), quercetin-3-O-arabinoside (quercetin-3-O-arabinoside), apigenin-7-O-nobi-nobiside (api-genin-7-O-neohesperidoside). [0003] Duyiwei soft capsule is a preparation made of unique medicinal ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/53A61K9/48A61K47/44A61K47/26A61K47/42A61P29/00A61P19/08
Inventor 马海波张硕张云王敏郭卿李双梅吴少聪
Owner SHIJIAZHUANG HUAXIN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap