Hair Care Product

Abstract

With an object of discovering a substance having a testosterone 5α-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and of providing a hair care product having this substance blended therein, and a hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance as an active ingredient thereof, a hair care product of the present invention is made to contain corosolic acid therein, and each of a hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter of the present invention is made to contain corosolic acid as an active ingredient thereof.

Description

TECHNICAL FIELD[0001]The present invention relates to a hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter, a bone morphogenetic protein-2 production promoter, and a hair care product.BACKGROUND ART[0002]Many steroid hormones exhibit their action upon binding to a receptor in the molecular form secreted from the producing organ, but in the case of male hormones called androgens, for example testosterone enters into cells of the target organ and is reduced to 5α-dihydrotestosterone (5α-DHT) by testosterone 5α-reductase, and the 5α-DHT binds to a receptor and exhibits action as an androgen.[0003]Androgens are important hormones, but if androgens act excessively, then various undesirable symptoms are brought about such as male pattern alopecia, hypertrichosis, seborrhea, acne (pimples etc.), benign prostatic hypertrophy, prostatic tumor,...

AI Technical Summary

Benefits of technology

[0024]According to the present invention, a hair care product containing corosolic acid therein, and a hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 (FGF-7) production promoter, a vascular endothelial growth factor (VEGF) production promoter, and a bone morphogenetic protein-2 (BMP-2) production promoter containing corosolic acid as an active ingredient thereof are provided.

[0025]According to the hair care product of the present invention, the testosterone 5α-reductase inhibiting action of corosolic acid allows preventing / ameliorating disorders in which male hormones are involved, while the hair papilla cell growth promoting action of corosolic acid allows preventing / ameliorating alopecia. According to the hair care product of the present invention, the fibroblast growth factor-7 (FGF-7) production promoting action, the vascular endothelial growth factor (VEGF) production promoting action or the bone morphogenetic protein-2 (BMP-2) production promoting action of corosolic acid allow preventing / ameliorating alopecia.

[0026]Through the testosterone 5α-reductase inhibiting action of corosolic acid as the effective ingredient, the hair growth tonic of the present invention allows curbing the effect of male hormones and preventing / ameliorating alopecia, while through the hair papilla cell growth promoting action of corosolic acid as the effective ingredient, the hair growth tonic of the present invention allows promoting hair growth / development thereby preventing / ameliorating alopecia. Through the fibroblast growth factor-7 production promoting action, vascular endothelial growth factor production promoting action or bone morphogenetic protein-2 production promoting action of corosolic acid as the effective ingredient, the hair growth tonic of the present invention allows preventing / ameliorating male pattern alopecia. Through the testosterone 5α-reductase inhibiting action of corosolic acid as the effective ingredient, also, the testosterone 5α-reductase inhibitor of the present invention allows curbing the effect of male hormones, and allows preventing / ameliorating disorders in which male hormones are involved. Through the hair papilla cell growth promoting action of corosolic acid as the effective ingredient, moreover, the hair papilla cell growth promoter of the present invention allows promoting the proliferation of hair papilla cells, thereby preventing / ameliorating alopecia. Through the fibroblast growth factor-7 (FGF-7) production promoting action of corosolic acid as the effective ingredient, furthermore, the fibroblast growth factor-7 (FGF-7) production promote of the present invention allows promoting the production of fibroblast growth factor-7, thereby preventing / ameliorating alopecia. Also, the vascular endothelial growth factor (VEGF) production promoter of the present invention allows promoting the production of vascular endothelial growth factor, thereby preventing / ameliorating alopecia. Moreover, the bone morphogenetic protein-2 (BMP-2) production promoter of the present invention allows promoting the production of bone morphogenetic protein-2, thereby preventing / ameliorating alopecia.

Problems solved by technology

Androgens are important hormones, but if androgens act excessively, then various undesirable symptoms are brought about such as male pattern alopecia, hypertrichosis, seborrhea, acne (pimples etc.), benign prostatic hypertrophy, prostatic tumor, and boy's sexual precocity.

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