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Compositions, methods and kits for enhancing weight loss while inhibiting loss of lean body mass

A technology of physique and mixture, which is applied in the field of diet and nutritional supplements, and can solve problems such as reducing lean body mass

Inactive Publication Date: 2009-07-22
SHAKLEE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although many researchers are working on the complex knowledge of physiological energy utilization under caloric restriction, existing nutritional supplements and regimens still result in undesired loss of lean body mass

Method used

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  • Compositions, methods and kits for enhancing weight loss while inhibiting loss of lean body mass
  • Compositions, methods and kits for enhancing weight loss while inhibiting loss of lean body mass
  • Compositions, methods and kits for enhancing weight loss while inhibiting loss of lean body mass

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] raw material

[0067] Soy protein / chromium / free leucine (SCL) compositions for inhibiting loss of lean body mass under conditions of calorie restriction are disclosed herein. The composition contains a certain amount of soybean protein, chromium and free leucine, which can effectively inhibit or even prevent the loss of lean body mass of individuals under caloric restriction conditions.

[0068] As used herein, soy protein refers to protein components obtained from soybean plants and / or concentrated sources such as soy protein isolates. In some cases soy protein is isolated from soybeans by methods well known in the art. For example, a concentrated soy protein fraction is prepared from clean, dehulled soybeans by removing most of the non-protein components such that the isolate contains at least about 80% protein by total weight, including moisture. The soy protein isolate is produced through a series of steps in which the soy protein fraction is separated from most s...

Embodiment 2

[0083] Ways to Promote Weight Loss

[0084] This example discloses a general method for promoting weight loss and / or improving lipid profile. The method comprises ingesting a combination of soy protein, chromium, and free leucine in an amount sufficient to inhibit loss of lean body mass under conditions of calorie restriction. As used herein, weight loss means a conscious effort to lose weight, whether measured by weight or by another measure of weight loss (eg, body mass index or BMI). In some instances, the soy protein / chromium / free leucine combination is ingested as a combined soy protein / chromium / free leucine composition, as described above. In other cases, soy protein, free leucine, and chromium were ingested separately. In some instances, the method also includes instructions for a calorie-restricted diet. In some embodiments, the method promotes weight loss in a subject with metabolic syndrome.

[0085] Also disclosed is a method for treating an overweight subject c...

Embodiment 3

[0098] Reagent test kit

[0099] The components of a dietary regimen may be provided in a kit, such as a package that may or may not contain instructions for a calorie-restricted diet; instructions for following or not following any particular diet; and / or intentionally following or Not intending to follow the instructions for a calorie-restricted diet. In other embodiments, the subject is instructed or not instructed to follow the formulated exercise regimen.

[0100] These kits may include compositions described elsewhere in this specification. For example, the kit may contain powdered drink mixes, snack bars, tea mixes, and supplements.

[0101] The instructions provided with the kit are in fixed form, for example in written form or recorded on audio cassette, video tape, compact disc or digital video disc. The instructions instruct the individual on the amount of the kit components to be ingested by the individual to inhibit the loss of lean body mass while eating, or t...

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PUM

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Abstract

Disclosed are combinations of soy protein, chromium and free leucine in amounts effective to inhibit the loss of lean body mass of a subject under conditions of caloric restriction. The soy protein, chromium and free leucine can be administered in several products, including a powder that is mixable into a liquid beverage (such as a shake), a snack bar, and a nutritional supplement (such as one or more tablets). Some embodiments also include corosolic acid and / or a tea drink that provides an effective dose of taurine. The products may be contained in kits containing the disclosed combinations as well as methods of using the products for weight loss and the inhibition of the loss of lean body mass in a subject during weight loss. The products and methods are also useful in the improvement of lipid profiles (for example reducing total cholesterol and LDL cholesterol levels).

Description

[0001] priority [0002] This application claims priority to US Patent Application Serial No. 11 / 452,004, filed June 12,2006. technical field [0003] The products and methods disclosed herein relate to diets and nutritional supplements for use in weight loss programs. Background technique [0004] Obesity has been recognized as a public health problem in the United States and around the world. Individuals who are overweight or obese are at high risk of developing conditions such as high blood pressure, dyslipidemia, type 2 diabetes (non-insulin dependent diabetes or NIDDM), coronary heart disease, stroke, gallbladder disease, osteoarthritis, sleep apnea and breathing problems . Obesity is also associated with a higher prevalence of endometrial, breast, prostate and colon cancers. It's no surprise, then, that obesity is also associated with increased mortality and premature infant deaths. [0005] The pharmaceutical industry has developed some drugs to help people lose w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/198A61K33/00A61K38/00A61K36/48A61P3/04A61P3/06A61P3/10A61P21/06A23L33/00A61K31/555A61K33/24
CPCA61K33/00A61K38/168A61K36/48A61K31/198A23L1/304A61K45/06A23V2002/00A61K33/06A61K38/00A23L1/3051A23L1/296A61K33/24A61K33/30A23L1/3055A23L2/52A23L33/40A23L33/16A23L33/175A23L33/185A61P21/06A61P3/04A61P3/06A61P3/10A61K2300/00A23V2250/5488A23V2250/1586A23V2250/0628A23V2250/1642A23V2250/161A23V2250/1636A23V2250/0644A23V2250/21A23V2200/08A23V2200/332
Inventor L·费希尔J·麦克马努斯K·泰勒山口春声
Owner SHAKLEE CORP
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