140results about How to "Improve heterogeneity" patented technology

The invention provides a method for identifying and interpreting carbonate rock ancient karst reservoir layer three-dimensional structure. Steps of identifying a single well cave preferably comprise that: according to a cave growing segment with definite rock core and electric imaging well logging information, conventional well logging response characteristics of the cave growing segment are summarized; cave sensitive well logging parameters are preferably selected via a well logging parameter intersection method, and an identification graph plate is established; a multi-parameter normalization weighting method is utilized to establish a cave identification function; steps of identifying an inter-well cave preferably comprise that: a synthetic seismic recording method is utilized toward each single well to calibrate a cave interpreting result of a depth domain to an acoustic inversion data volume of a time domain; then threshold values of a cave segment and a non-cave segment are confirmed so that the inter-well cave is effectively identified; continuous tracking is performed along the middle of caves which are large in scale and great in continuity so that a three-dimensional tracking layer is obtained, an average value of 2ms acoustic save impedance around the tracking layer is computed, and thus a three-dimensional space growing position of an ancient karst reservoir layer is obtained.

The invention discloses a distributed traffic simulating platform based on a Service-Oriented Architecture (SOA) and a simulating method thereof. The distributed traffic simulating platform mainly comprises modules, such as an interactive intelligent agent, a simulating result processing intelligent agent, a coordinating intelligent agent, a road network generating intelligent agent, an area simulating module, a data service center, and the like. The simulation based on a large-scale real road network is finished by the mutual coordination of different intelligent agents. The modules are finished by a service component architecture (SCA), Visual C++ and Visual Basic. In addition, the invention is provided with an SOA access module based on the SCA, which is used for integrating the traditional single-machine simulating program. The invention meets the requirement of the distributed simulating platform on isomerism, improves the flexibility of a system, the reusability of a business model and the interoperability of service and leads the system to be easy for integration.

A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed mimic receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. A system in accordance with some embodiments is a contact lens for delivering a drug through contact with an eye. In some embodiments, the drug is an anti-microbial, such as an anti-fungal agent for treatment of large animals. In some embodiments, a comfort molecule hyaluronic acid (HA) is delivered. In some embodiments, ketotifen fumarate (anti-histamine) and/or diclofenac sodium (anti-inflammatory) are delivered.

The present embodiments relate to producing a radiation treatment plan. In one embodiment, the method may include specifying a dataset in which an object requiring to be irradiated is represented; determining a target volume requiring to be irradiated within the object; ascertaining a metric identifying a density heterogeneity for a region that will be struck by the planned treatment beam; and determining as a function of the ascertained metric a safety margin for the target volume requiring to be irradiated.

The invention relates to a composite profile control and oil displacement extraction method for a thickened oil reservoir through water injection and exploitation. The method provided by the invention comprises the following steps: preparing a polymer and water into a polymer solution with the concentration of 500-5000mg/L; preparing a cross-linking agent and water into a cross-linking agent solution with the concentration of 500-5000mg/L; mixing the polymer solution and the cross-linking agent solution according to the mass ratio of (1:1)-(10:1) to obtain a polymer gel solution; preparing a movable micro-gel and water into a movable micro-gel solution with the concentration of 1000-5000mg/L; respectively injecting the polymer gel solution and the movable micro-gel solution into a well to form an oil displacement segmentation plug, wherein the polymer is partial hydrolysis polyacrylamide; the cross-linking agent is an organic chromium cross-linking agent; and the movable micro-gel is a copolymer of acrylamide and N-N methylene bisacrylamide. The method provided by the invention can obviously improve the anisotropism in storage layers, among the layers and on planes, relieves the water injection and exploitation contradictions of the oil reservoir, solves the problems of tonguing and fingering and obviously enlarges the swept volume of a displacing solution, thereby greatly improving the recovery ratio of crude oil.

Methods, program code, computer readable medium, and apparatus estimating permeability at unsampled (uncored) but logged interval locations in a reservoir based upon a similarity with log signatures from cored intervals, are provided. An example of a method can include performing a core plug-by-core plug blind test, defining an objective function which qualifies the quality of the permeability prediction to minimize discrepancies between measured and predicted permeability, optimizing calculated parameters, and estimating permeability values of uncored logged intervals. The method can also include applying a debiasing/variance restoration to compensate for inherent averaging artifacts

The invention discloses a crossed scraping-impacting composite drill bit belonging to the field of rock blasting tools for drilling equipment for oil and gas, mine engineering and building foundation engineering construction, geology, hydrology and the like. The crossed scraping-impacting composite drill bit comprises a drill bit body, a fixed cutting structure, a disc cutter cutting structure and a hydraulic structure, wherein the fixed cutting structure, the disc cutter cutting structure and the hydraulic structure are arranged on the drill bit body; the drill bit body is also provided with an impact cutting structure; and the impact cutting structure comprises a force transferring mechanism for transferring impact forces and impact cutting teeth, wherein the impact cutting teeth are solidified on a punch arranged at the tail end of the force transferring mechanism, and the punch can slide or slidingly impact relative to the drill bit body in the impact force transferring direction. Compared with a drill bit for blasting a rock in a cutting way, the crossed scraping-impacting composite drill bit is not only beneficial to the drilling of the cutting teeth of the drill bit to stratums and the increment of the rock blasting efficiency, but also beneficial to the retardance of the wear rate of the cutting teeth and particularly has remarkable technical advantages for higher-strength and stronger-abrasiveness stratums which are difficult to drill.

The invention discloses an ocean observation network system and method based on an EC-REST system structure. Edge sensing equipment of a data source for sensing ocean observation data performs preliminary processing and storage on the collected data; the data acquisition layer is used for acquiring and transmitting ocean observation data sensed by a data source and transmitting the acquired data to a data storage layer; the data storage layer preprocesses the data transmitted by the data acquisition layer by utilizing an edge gateway and then uploads the data to the data processing layer; thedata processing layer realizes unified and coordinated migration and scheduling of resource loads such as computing tasks among sensing devices deployed in a distributed manner and between the sensingdevices and the edge gateway through an EC-REST architecture for data uploaded by the edge gateway; and the data application layer applies the result processed by the data processing layer. Interactivity and resource load balance of each sensing device in the ocean observation network are maintained, and high-efficiency and low-energy-consumption real-time observation of massive heterogeneous data in the ocean is realized.

The invention provides an exome potential pathogenic mutation detection method based on a family line. The detection method comprises the following steps: 1) reading a result file of an exome sequencing data processing flow, and conducting function filtering; 2) reading the file obtained in the last step, extracting mutations in all samples, calculating a union set, and then combining all samples, so that a matrix is constituted; 3) extracting mutation information in the matrix obtained in the last step, enumerating and assessing pathogenicity of single mutation and pathogenicity of combined dual-site mutation, so that a potential pathogenic mutation list is obtained; and 4) in accordance with the list obtained in the last step, calculating the appearance situations of sites in various samples and target genes. According to the method disclosed by the invention, data integration and basic filtration are completed by taking an output result of the common exome sequencing processing flow as an input condition; by virtue of a special mutation screening algorithm, a candidate set of the potential pathogenic mutations is provided; and the method focuses on solving a problem on potential pathogenic mutation mining of sequencing data with high heterogeneity, high mutation rate and high noise.

The invention discloses a profile control-unplugging combining technique for a water injection well. The profile control-unplugging combining technique comprises the steps that (1), well input fluid is prepared; (2), pressure is gradually increased, water is injected into a stratum, a relation curve of injection pressure and displacement is drawn, and an injection pressure curve knee P* is determined; (3), a cellulose plugging agent A is injected at the injection pressure smaller than P* and used for remote well profile control; (4), a profile control agent B forming glue through acid catalysis is injected at the injection pressure smaller than P*; (5), displacement fluid is injected; (6), well shutting for waiting on cement setting is carried out for 2-6 hours; (7), acid liquor C is injected at the injection pressure larger than P*; (8), pressure release is carried out; (9), normal water injection is restored, and if normal water injection can be achieved, construction is completed. According to the profile control-unplugging combining technique for the water injection well, water reducing oil increase of a high water content oil well is achieved, profile control and unplugging ofthe multilayer oil deposit water injection well are achieved, an injection profile is improved, and the oilfield development effect is improved; and construction operation of the water injection wellis easy, convenient, safe and efficient, and wide market application prospects are achieved.

Heterosis designates the increased growth or other augmented action resulting from crossing, however it is produced. Male sterility of female parent is an important biological mechanism for the commercial production of hybrid seed. Male sterility can be created by genetic manipulation, environmental influences, chemical induction and biological engineering. In principle, male sterility is a physiological disorder and the creation of complete male sterility either is costly or brings about other physiological disordrs. Integrating the resistance gene to a non-selective herbicide into male parent and spraying the herbicide onto the hybrid population resulting from mating with the male parent for securing hybrid purity reduces the strict demand for complete male sterility. Therefore, simple and practical methodologies such as environmental and chemical means can be employed in the induction of male sterility, and the conflict of male sterility with other physiological disorders can be well balanced. The concept of this invention is applicable to all the crops and plants in which male sterility has been studied for heterosis purposes including, for example, forage and vegetable crops and cereals.

The invention relates to a temporary plugging steering acidification method applicable to a sandstone reservoir, which belongs to the technical field of yield increasing and injection increasing of oil and gas fields. By adopting pad-acid and synergistic liquid, the temporary plugging of a high permeable layer of the non-homogenous sandstone reservoir can be realized, and the temporary plugging performance is good, so that the subsequently injected main body acid liquid can be successfully diverted to enter a low permeable layer and to acidify the low permeable layer. By adopting the acidification method, the sandstone reservoir can be effectively and homogenously acidified, and the non-homogeneity of the reservoir can be improved.

A flexible manufacturing and executing system based on radio communication comprises data collection unit, RS232 communication interface, workshop information management unit, radio data transmitting unit, application program server APS, SQL server databank, web browser and web server. It is featured as transmitting collected data to APS through Internet network and radio data transmitting unit, storing said data in SQL server databank and forming decision after said data is processed by calling APS, issuing decision on web server and using web browser to link with web server by client end for carrying out access on decision content and for obtaining or inquiring data stored in SQL server databank. .

By altering amino acid sequences, the present inventors successfully produced constant regions that can confer antibodies with particularly favorable properties for pharmaceutical agents. When used to produce antibodies, the altered constant regions produced according to the present invention significantly reduce heterogeneity. Specifically, the antibody homogeneity can be achieved by using antibody heavy chain and light chain constant regions introduced with alterations provided by the present invention. More specifically, the alterations can prevent the loss of homogeneity of antibody molecules due to disulfide bond differences in the heavy chain. Furthermore, in a preferred embodiment, the present invention can improve antibody pharmacokinetics as well as prevent the loss of homogeneity due to C-terminal deletion in antibody constant region.

The invention discloses a cloud-based secure instant messaging method and system. The system comprises a sending end, a receiving end and a communication application server which are arranged at a cloud and a locally arranged key management center (KMC), wherein the KMC generates terminal initialization keys (TIKs), transmission master keys (TMKs), terminal local master keys (TLMKs) and terminal application keys (TAKs) and sends the keys to the sending end and the receiving end; the sending end and the receiving end each comprise a communication module and a key module, the communication module receives key data, the key module is in charge of decrypting, storing and managing the key data, establishing an encryption channel by use of the received TAKs, and the TAKs employed for establishing the encryption channel each time are different. Through the technical scheme provided by the invention, the safety of the whole system is high, the compatibility is good, and the isomerism is high.

This process makes it possible to manufacture articles of any shape by stamping, in which articles the matrix of the alloy has to have a coarse-grained structure. According to the invention, a partial hot-forming operation is carried out by stamping a blank made of an oxide-dispersion-strengthened alloy, especially a nickel-based alloy, having an initial ultrafine-grained structure, in order to form a shaped component, this shaped component is subjected to a secondary recrystallization heat treatment so as to develop an abnormal grain growth, and then a new hot-forming operation is carried out by stamping in order to give the recrystallized shaped component the final shape of the article.

A hydrocarbon well remediation/stimulation treatment based on an Y-Grade natural gas liquid injection fluid mixture, including prescribed amounts of gas, nanoparticles with wettability alteration properties, foaming agents (including nanoparticles with foam stabilization properties), and solvent additives. The fluid mixture may be tuned to address multiple factors contributing to production decline, such as liquid blockage, wettability properties, fines/debris/scale build-up and organic deposits, reservoir heterogeneity/permeability, and/or reservoir fluid and hydrocarbon compositions, resulting in hydrocarbon production enhancement. The treatment is typically applied with a Huff-n-Puff process, however may also be applied with a flooding process.

The invention discloses a method for modifying sandy soil and silt soil by electroosmosis and microbial grouting. The method comprises the following steps: firstly cultivating microbes for 24 hours in a fermentation medium to obtain a bacteria solution, injecting an electrolyte with the calcium ion concentration of 0.05 mol/L into a hollow electrode bar of the anode of an electroosmosis device, and continually electrifying; and then injecting the bacteria solution and nutritive salt into the hollow electrode bar of the anode of the electroosmosis device at intervals. In the whole process, continuous electrifying is performed, the voltage gradient between electrodes is controlled to be 0.5-1.0 V/cm, temperature changes in soil are monitored by a thermometer, and the soil temperature is controlled to be lower than 50 DEG C. Compared with the prior art, the method has the advantages that an additional electric field is applied to transfer the bacteria solution and nutritive salt, so that the distribution effect of microbe precipitated calcium carbonate in soil can be improved, and the adverse situation that the grouting effect is influenced by deposition of a large quantity of calcium carbonate near a grouting opening is improved.

The invention relates to an isothermal adsorption curve correction method based on a gravimetric method. The method comprises steps of carrying out a blank test before a rock core isothermal adsorption test, calculating the volume of a sample barrel under different test pressures, and finely characterizing the dynamic change of the volume of the sample barrel under different test pressures; respectively carrying out pretreatment test, buoyancy test and methane isothermal absorption test of a granular sample which is crushed to a laboratory test standard, in a buoyancy test phase, finely representing the dynamic change characteristics of the sample and the sample barrel under different test pressures, in combination with the dynamic change of the volume of the sample barrel under the same test pressure, constructing a dynamic change mathematical model of the sample volume under different test pressures, realizing fine representation of the sample volume under different test pressures, calculating the adsorbed state methane mass under different test pressures in the methane absorption test stage based on the fine representation, and drawing an accurate isothermal absorption curve based on a gravimetric method. The method can effectively guide evaluation of coal bed gas, shale gas and other unconventional natural gas resources.

Spectral clustering is used for clustering high dimensional data via sparse representation. The sparsity is increased by data pre-processing via weighted local principal component analysis. The approach is suitable for many applications, including financial applications such as anti-money laundering (AML). Other features are also provided.

The invention discloses a spectral characteristic variable selection and optimization method based on a Stacking integration framework, and the method comprises the steps: constructing a sample set, and dividing the sample set into a training sample set and a testing sample set; selecting a representative characteristic variable selection method from the large classes of the variable interval selection method, the variable information selection method and the variable optimization selection method; constructing a plurality of base learners, integrating the base learners by adopting a Stackingintegration framework, constructing a meta-learner, and taking the output of the base learners as the input of the meta-learner; training and testing a base learner and a meta learner of the Stackingintegrated framework by using the sample set; and inputting the to-be-detected spectrum information into the basic learner, and obtaining a detection result of the to-be-detected spectrum according tothe output of the meta-learner. According to the spectral characteristic variable selection and optimization method based on the Stacking integrated framework, the defects of a single characteristicvariable selection method are overcome, the detection precision of a test sample is high, and the stability of a detection result is good.