141results about How to "Improve heterogeneity" patented technology

The present embodiments relate to producing a radiation treatment plan. In one embodiment, the method may include specifying a dataset in which an object requiring to be irradiated is represented; determining a target volume requiring to be irradiated within the object; ascertaining a metric identifying a density heterogeneity for a region that will be struck by the planned treatment beam; and determining as a function of the ascertained metric a safety margin for the target volume requiring to be irradiated.

The invention provides a method for identifying and interpreting carbonate rock ancient karst reservoir layer three-dimensional structure. Steps of identifying a single well cave preferably comprise that: according to a cave growing segment with definite rock core and electric imaging well logging information, conventional well logging response characteristics of the cave growing segment are summarized; cave sensitive well logging parameters are preferably selected via a well logging parameter intersection method, and an identification graph plate is established; a multi-parameter normalization weighting method is utilized to establish a cave identification function; steps of identifying an inter-well cave preferably comprise that: a synthetic seismic recording method is utilized toward each single well to calibrate a cave interpreting result of a depth domain to an acoustic inversion data volume of a time domain; then threshold values of a cave segment and a non-cave segment are confirmed so that the inter-well cave is effectively identified; continuous tracking is performed along the middle of caves which are large in scale and great in continuity so that a three-dimensional tracking layer is obtained, an average value of 2ms acoustic save impedance around the tracking layer is computed, and thus a three-dimensional space growing position of an ancient karst reservoir layer is obtained.

The invention discloses a distributed traffic simulating platform based on a Service-Oriented Architecture (SOA) and a simulating method thereof. The distributed traffic simulating platform mainly comprises modules, such as an interactive intelligent agent, a simulating result processing intelligent agent, a coordinating intelligent agent, a road network generating intelligent agent, an area simulating module, a data service center, and the like. The simulation based on a large-scale real road network is finished by the mutual coordination of different intelligent agents. The modules are finished by a service component architecture (SCA), Visual C++ and Visual Basic. In addition, the invention is provided with an SOA access module based on the SCA, which is used for integrating the traditional single-machine simulating program. The invention meets the requirement of the distributed simulating platform on isomerism, improves the flexibility of a system, the reusability of a business model and the interoperability of service and leads the system to be easy for integration.

A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed mimic receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. A system in accordance with some embodiments is a contact lens for delivering a drug through contact with an eye. In some embodiments, the drug is an anti-microbial, such as an anti-fungal agent for treatment of large animals. In some embodiments, a comfort molecule hyaluronic acid (HA) is delivered. In some embodiments, ketotifen fumarate (anti-histamine) and / or diclofenac sodium (anti-inflammatory) are delivered.

The present embodiments relate to producing a radiation treatment plan. In one embodiment, the method may include specifying a dataset in which an object requiring to be irradiated is represented; determining a target volume requiring to be irradiated within the object; ascertaining a metric identifying a density heterogeneity for a region that will be struck by the planned treatment beam; and determining as a function of the ascertained metric a safety margin for the target volume requiring to be irradiated.

The invention relates to a composite profile control and oil displacement extraction method for a thickened oil reservoir through water injection and exploitation. The method provided by the invention comprises the following steps: preparing a polymer and water into a polymer solution with the concentration of 500-5000mg / L; preparing a cross-linking agent and water into a cross-linking agent solution with the concentration of 500-5000mg / L; mixing the polymer solution and the cross-linking agent solution according to the mass ratio of (1:1)-(10:1) to obtain a polymer gel solution; preparing a movable micro-gel and water into a movable micro-gel solution with the concentration of 1000-5000mg / L; respectively injecting the polymer gel solution and the movable micro-gel solution into a well to form an oil displacement segmentation plug, wherein the polymer is partial hydrolysis polyacrylamide; the cross-linking agent is an organic chromium cross-linking agent; and the movable micro-gel is a copolymer of acrylamide and N-N methylene bisacrylamide. The method provided by the invention can obviously improve the anisotropism in storage layers, among the layers and on planes, relieves the water injection and exploitation contradictions of the oil reservoir, solves the problems of tonguing and fingering and obviously enlarges the swept volume of a displacing solution, thereby greatly improving the recovery ratio of crude oil.

The invention discloses a particulate profile control agent self-adaptive to a pore throat size of a stratum and a preparation method for the particulate profile control agent. The particulate profilecontrol agent is prepared from the raw materials in percentage by mass: 0.04%-0.2% of main agent, 0.005%-0.01% of coagulation agent, 0.002%-0.04% of cross-linker, 0.005%-0.01% of additive and the balance of water. The preparation method for the profile control agent comprises the steps of proportionally adding the main agent into the water, carrying out uniform stirring, and then, sequentially adding the additive, the cross-linker and the coagulation agent, thereby forming the profile control agent. Colloidal particles can be formed in situ through pumping the profile control agent into the stratum and carrying out a reaction for a period of time at an oil reservoir temperature, and thus, a high-permeability layer can be plugged. The particulate profile control agent and the preparation method therefor have the advantages that the preparing of the profile control agent is simple and convenient in operation and low in cost; a system is low in initial viscosity and good in injectivity;the particulate profile control agent can react in situ to produce colloidal particles highly matched with pores and cracks of the stratum, the strength of plugging is high, and the reaction time is controllable; and the particulate profile control agent is wide in oil reservoir adaptability and good in colloidal particle viscoelasticity, has the ability for deep migration and can perform pluggingin the oil reservoir step by step, and thus, the recovery ratio of crude oil is remarkably increased.

Methods, program code, computer readable medium, and apparatus estimating permeability at unsampled (uncored) but logged interval locations in a reservoir based upon a similarity with log signatures from cored intervals, are provided. An example of a method can include performing a core plug-by-core plug blind test, defining an objective function which qualifies the quality of the permeability prediction to minimize discrepancies between measured and predicted permeability, optimizing calculated parameters, and estimating permeability values of uncored logged intervals. The method can also include applying a debiasing / variance restoration to compensate for inherent averaging artifacts

The invention discloses a three-dimensional visualization modeling method for a water bearing / resisting stratum of coal measures, and the method comprises the steps: preparing the base materials of research; building a corresponding fault model according to a digitalized structural map and break point data; carrying out the dividing of the water-bearing stratum and the water-resisting stratum, recognizing a corresponding bearing / resisting stratum interface, building a bearing / resisting stratum stratigraphic framework, and building a corresponding stratum model through the Kriging interpolation method; carrying out the research of deposition geologic features of the stratum of the coal measures, and building a depositional microfacies model through combining sequential indication simulation with the sedimentary microfacies distribution features; taking the phase control technology and theory as the basis, and building a physical model of the water-bearing stratum according to the collected and calculated physical data; and displaying the spatial distribution rule of the bearing / resisting stratum of coal measures according to the finally built related model. According to the invention, the method carries out the objective description of the spatial distribution of the bearing / resisting stratum through modeling, visually reflects the three-dimensional spatial distribution of the bearing / resisting stratum and the water abundance features of the water-bearing stratum, and provides a three-dimensional visualization basis for the research of the bearing / resisting stratum.

The invention discloses a crossed scraping-impacting composite drill bit belonging to the field of rock blasting tools for drilling equipment for oil and gas, mine engineering and building foundation engineering construction, geology, hydrology and the like. The crossed scraping-impacting composite drill bit comprises a drill bit body, a fixed cutting structure, a disc cutter cutting structure and a hydraulic structure, wherein the fixed cutting structure, the disc cutter cutting structure and the hydraulic structure are arranged on the drill bit body; the drill bit body is also provided with an impact cutting structure; and the impact cutting structure comprises a force transferring mechanism for transferring impact forces and impact cutting teeth, wherein the impact cutting teeth are solidified on a punch arranged at the tail end of the force transferring mechanism, and the punch can slide or slidingly impact relative to the drill bit body in the impact force transferring direction. Compared with a drill bit for blasting a rock in a cutting way, the crossed scraping-impacting composite drill bit is not only beneficial to the drilling of the cutting teeth of the drill bit to stratums and the increment of the rock blasting efficiency, but also beneficial to the retardance of the wear rate of the cutting teeth and particularly has remarkable technical advantages for higher-strength and stronger-abrasiveness stratums which are difficult to drill.

According to various embodiments of the present invention, an electronic device can comprise: a housing; a flexible display of which at least a portion is accommodated in the housing, wherein the flexible display comprises a window forming at least a portion of the outer side surface of the electronic device, a light-emitting layer arranged below the window, and a protective layer arranged below the light-emitting layer, a transparent region for transmitting light incident from the outside of the electronic device is formed in a portion of a region of the light-emitting layer, and an opening of which at least a portion is aligned with the transparent region is formed in a portion of a region of the protective layer; and a sensor of which at least a portion is accommodated in the housing and at least a portion is aligned with the opening. The electronic device can vary according to embodiments.

The invention discloses an ocean observation network system and method based on an EC-REST system structure. Edge sensing equipment of a data source for sensing ocean observation data performs preliminary processing and storage on the collected data; the data acquisition layer is used for acquiring and transmitting ocean observation data sensed by a data source and transmitting the acquired data to a data storage layer; the data storage layer preprocesses the data transmitted by the data acquisition layer by utilizing an edge gateway and then uploads the data to the data processing layer; thedata processing layer realizes unified and coordinated migration and scheduling of resource loads such as computing tasks among sensing devices deployed in a distributed manner and between the sensingdevices and the edge gateway through an EC-REST architecture for data uploaded by the edge gateway; and the data application layer applies the result processed by the data processing layer. Interactivity and resource load balance of each sensing device in the ocean observation network are maintained, and high-efficiency and low-energy-consumption real-time observation of massive heterogeneous data in the ocean is realized.

The invention provides an exome potential pathogenic mutation detection method based on a family line. The detection method comprises the following steps: 1) reading a result file of an exome sequencing data processing flow, and conducting function filtering; 2) reading the file obtained in the last step, extracting mutations in all samples, calculating a union set, and then combining all samples, so that a matrix is constituted; 3) extracting mutation information in the matrix obtained in the last step, enumerating and assessing pathogenicity of single mutation and pathogenicity of combined dual-site mutation, so that a potential pathogenic mutation list is obtained; and 4) in accordance with the list obtained in the last step, calculating the appearance situations of sites in various samples and target genes. According to the method disclosed by the invention, data integration and basic filtration are completed by taking an output result of the common exome sequencing processing flow as an input condition; by virtue of a special mutation screening algorithm, a candidate set of the potential pathogenic mutations is provided; and the method focuses on solving a problem on potential pathogenic mutation mining of sequencing data with high heterogeneity, high mutation rate and high noise.

A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed preferably mimic receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. A system in accordance with an embodiment of the invention is a contact lens for delivering a drug through contact with an eye. In a particular embodiment of the invention, the drug is an anti-microbial, such as an anti-fungal agent for treatment of large animals, such as horses.

The invention discloses a profile control-unplugging combining technique for a water injection well. The profile control-unplugging combining technique comprises the steps that (1), well input fluid is prepared; (2), pressure is gradually increased, water is injected into a stratum, a relation curve of injection pressure and displacement is drawn, and an injection pressure curve knee P* is determined; (3), a cellulose plugging agent A is injected at the injection pressure smaller than P* and used for remote well profile control; (4), a profile control agent B forming glue through acid catalysis is injected at the injection pressure smaller than P*; (5), displacement fluid is injected; (6), well shutting for waiting on cement setting is carried out for 2-6 hours; (7), acid liquor C is injected at the injection pressure larger than P*; (8), pressure release is carried out; (9), normal water injection is restored, and if normal water injection can be achieved, construction is completed. According to the profile control-unplugging combining technique for the water injection well, water reducing oil increase of a high water content oil well is achieved, profile control and unplugging ofthe multilayer oil deposit water injection well are achieved, an injection profile is improved, and the oilfield development effect is improved; and construction operation of the water injection wellis easy, convenient, safe and efficient, and wide market application prospects are achieved.

Heterosis designates the increased growth or other augmented action resulting from crossing, however it is produced. Male sterility of female parent is an important biological mechanism for the commercial production of hybrid seed. Male sterility can be created by genetic manipulation, environmental influences, chemical induction and biological engineering. In principle, male sterility is a physiological disorder and the creation of complete male sterility either is costly or brings about other physiological disordrs. Integrating the resistance gene to a non-selective herbicide into male parent and spraying the herbicide onto the hybrid population resulting from mating with the male parent for securing hybrid purity reduces the strict demand for complete male sterility. Therefore, simple and practical methodologies such as environmental and chemical means can be employed in the induction of male sterility, and the conflict of male sterility with other physiological disorders can be well balanced. The concept of this invention is applicable to all the crops and plants in which male sterility has been studied for heterosis purposes including, for example, forage and vegetable crops and cereals.

A flexible manufacturing and executing system based on radio communication comprises data collection unit, RS232 communication interface, workshop information management unit, radio data transmitting unit, application program server APS, SQL server databank, web browser and web server. It is featured as transmitting collected data to APS through Internet network and radio data transmitting unit, storing said data in SQL server databank and forming decision after said data is processed by calling APS, issuing decision on web server and using web browser to link with web server by client end for carrying out access on decision content and for obtaining or inquiring data stored in SQL server databank. .

By altering amino acid sequences, the present inventors successfully produced constant regions that can confer antibodies with particularly favorable properties for pharmaceutical agents. When used to produce antibodies, the altered constant regions produced according to the present invention significantly reduce heterogeneity. Specifically, the antibody homogeneity can be achieved by using antibody heavy chain and light chain constant regions introduced with alterations provided by the present invention. More specifically, the alterations can prevent the loss of homogeneity of antibody molecules due to disulfide bond differences in the heavy chain. Furthermore, in a preferred embodiment, the present invention can improve antibody pharmacokinetics as well as prevent the loss of homogeneity due to C-terminal deletion in antibody constant region.

The invention discloses an injection-production production pattern constructing method for a carbonatite fault-karst reservoir. The method includes the steps that a geophysics method is used for recognizing and representing a fracture-cavity structure of carbonatite fault-karst; based on recognition and representation of the fracture-cavity structure, a conceptual model of the carbonatite fault-karst is obtained in an abstract equivalent way; based on representation and the conceptual model for the fracture-cavity structure, a mechanism model for the carbonatite fault-karst is established, and according to the mechanism model, an injection-production pattern for the carbonatite fault-karst reservoir is designed.

The invention discloses a cloud-based secure instant messaging method and system. The system comprises a sending end, a receiving end and a communication application server which are arranged at a cloud and a locally arranged key management center (KMC), wherein the KMC generates terminal initialization keys (TIKs), transmission master keys (TMKs), terminal local master keys (TLMKs) and terminal application keys (TAKs) and sends the keys to the sending end and the receiving end; the sending end and the receiving end each comprise a communication module and a key module, the communication module receives key data, the key module is in charge of decrypting, storing and managing the key data, establishing an encryption channel by use of the received TAKs, and the TAKs employed for establishing the encryption channel each time are different. Through the technical scheme provided by the invention, the safety of the whole system is high, the compatibility is good, and the isomerism is high.

This process makes it possible to manufacture articles of any shape by stamping, in which articles the matrix of the alloy has to have a coarse-grained structure. According to the invention, a partial hot-forming operation is carried out by stamping a blank made of an oxide-dispersion-strengthened alloy, especially a nickel-based alloy, having an initial ultrafine-grained structure, in order to form a shaped component, this shaped component is subjected to a secondary recrystallization heat treatment so as to develop an abnormal grain growth, and then a new hot-forming operation is carried out by stamping in order to give the recrystallized shaped component the final shape of the article.

The invention discloses a particle diameter and rock property well-logging evaluation method under restraint of depositional microfacies, and belongs to the technical field of reservoir well-logging evaluation research. The particle diameter and rock property well-logging evaluation method is characterized in that mudstones are split through a well-logging data-well-logging curve, well-logging recognition on five particle diameter and rock property disclosed thick layers of coarse sandstones, sandy conglomerate, medium sandstones, fine sandstones and siltstones is performed in rock physical model-depositional microfacies well-logging evaluation units to determine heterogeneity of a low-permeability and compact sandstone reservoir; the rock physical model-depositional microfacies well-logging evaluation units are divided out from geologic origin, and innovation is obtained from well-logging recognition on thick layers and the rock property of low-permeability and compact sandstone reservoir; and well-logging data, well-logging information and analysis test data are integrated, so that mudstones split by the well-logging data-well-logging curve and different particle diameters and rock property recognized in the rock physical model-depositional microfacies well-logging evaluation units are combined to form the evaluation method.

A hydrocarbon well remediation / stimulation treatment based on an Y-Grade natural gas liquid injection fluid mixture, including prescribed amounts of gas, nanoparticles with wettability alteration properties, foaming agents (including nanoparticles with foam stabilization properties), and solvent additives. The fluid mixture may be tuned to address multiple factors contributing to production decline, such as liquid blockage, wettability properties, fines / debris / scale build-up and organic deposits, reservoir heterogeneity / permeability, and / or reservoir fluid and hydrocarbon compositions, resulting in hydrocarbon production enhancement. The treatment is typically applied with a Huff-n-Puff process, however may also be applied with a flooding process.

The invention discloses a method for modifying sandy soil and silt soil by electroosmosis and microbial grouting. The method comprises the following steps: firstly cultivating microbes for 24 hours in a fermentation medium to obtain a bacteria solution, injecting an electrolyte with the calcium ion concentration of 0.05 mol / L into a hollow electrode bar of the anode of an electroosmosis device, and continually electrifying; and then injecting the bacteria solution and nutritive salt into the hollow electrode bar of the anode of the electroosmosis device at intervals. In the whole process, continuous electrifying is performed, the voltage gradient between electrodes is controlled to be 0.5-1.0 V / cm, temperature changes in soil are monitored by a thermometer, and the soil temperature is controlled to be lower than 50 DEG C. Compared with the prior art, the method has the advantages that an additional electric field is applied to transfer the bacteria solution and nutritive salt, so that the distribution effect of microbe precipitated calcium carbonate in soil can be improved, and the adverse situation that the grouting effect is influenced by deposition of a large quantity of calcium carbonate near a grouting opening is improved.

The invention relates to an isothermal adsorption curve correction method based on a gravimetric method. The method comprises steps of carrying out a blank test before a rock core isothermal adsorption test, calculating the volume of a sample barrel under different test pressures, and finely characterizing the dynamic change of the volume of the sample barrel under different test pressures; respectively carrying out pretreatment test, buoyancy test and methane isothermal absorption test of a granular sample which is crushed to a laboratory test standard, in a buoyancy test phase, finely representing the dynamic change characteristics of the sample and the sample barrel under different test pressures, in combination with the dynamic change of the volume of the sample barrel under the same test pressure, constructing a dynamic change mathematical model of the sample volume under different test pressures, realizing fine representation of the sample volume under different test pressures, calculating the adsorbed state methane mass under different test pressures in the methane absorption test stage based on the fine representation, and drawing an accurate isothermal absorption curve based on a gravimetric method. The method can effectively guide evaluation of coal bed gas, shale gas and other unconventional natural gas resources.

The invention discloses a chromium-aluminum ion compound profile control agent for a highly permeable duct type oil deposit and a use method thereof and relates to the field of applied chemistry of oil fields. The profile control agent provided by the invention is injected into the highly permeable duct type oil deposit in form a double section slug. A plurality of high molecular polyacrylamides and additives are mixed in the preposed section slug to form a compound polymer to block a highly permeable region and large ducts in the oil deposit; a plurality of low molecular polyacrylamides and additives are mixed in the post-posed section slug to boast the characteristics of low viscosity, high mobility and shear resistance. After the pre-posed section slug is blocked, the profile control agent injected into the oil deposit for profile control and displacement, so that small scaled water channeling and fingering phenomena generated by water drive after blocking can be inhibited; the profile control agent contains a proper amount of surfactant, so that the hydrophilicity of rocks of the oil deposit can be improved and a phenomenon that waxiness, colloids and asphaltene which are hard to control by a conventional profile control method are deposited in an immediate vicinity of wellbore is inhibited. The profile control agent disclosed by the invention is simple in preparation method and can be suitable for prepared water, the degree of mineralization of which is 500-35000mg / L, and the raw materials are cheap and easily available.

The invention relates to a low-permeability sandstone reservoir composite polymer type profile control agent and its application method, which relate to the field of oilfield applied chemistry. The present invention injects low-permeability sandstone reservoirs in the form of double slugs. The pre-slug is a multi-molecular compound polymer, which can be combined with insoluble suspended matter particles in the reservoir to form a polymer with a molecular coil structure around the core. Selective plugging of micro-fractures and large pores in the reservoir; the rear slug is a low-viscosity compound polymer, and an appropriate amount of clay stabilizer and surfactant is added to control and flood unplugged areas, which can suppress low-viscosity The phenomenon of clay swelling in seepage sandstone reservoirs can improve the deposition of wax, colloid and asphaltene near the wellbore; the invention can improve the heterogeneity of reservoirs, increase the follow-up water flooding sweep coefficient, and suppress dead oil areas in low-permeability sandstone reservoirs Formed to improve the disadvantages of traditional oil recovery methods such as low recovery rate and poor economic benefits of low-permeability sandstone reservoirs.

Spectral clustering is used for clustering high dimensional data via sparse representation. The sparsity is increased by data pre-processing via weighted local principal component analysis. The approach is suitable for many applications, including financial applications such as anti-money laundering (AML). Other features are also provided.

The invention provides an oil-resistant adsorption-resistant low-tension foam oil-displacing agent and a preparation method and application thereof, belongs to the technical field of oil-displacing agents, and aims to solve the technical problem that an existing foam oil-displacing agent cannot have oil resistance and adsorption resistance at the same time on the premise of meeting set performance. The oil-resistant adsorption-resistant low-tension foam oil-displacing agent is prepared from the following components in percentage by mass: 30 to 40 percent of fatty alcohol-polyoxyethylene etherglucoside, 20 to 30 percent of alpha-alkenyl sulfonate, 10 to 15 percent of coconut oil acid / lauric acid monoisopropanolamide, 5 to 10 percent of low-carbon alcohol and the balance of water. The foamoil-displacing agent has good oil resistance and adsorption resistance while meeting the established characteristics of the foam oil-displacing agent, can effectively improve the recovery ratio and reduce waste in actual field application, and meets the green and environment-friendly requirements.