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192results about How to "Avoid effectiveness" patented technology

Genetic inhibition by double-stranded RNA

InactiveUS20080050342A1Low concentrationEffectiveness of inhibitionOrganic active ingredientsBiocideGene expressionNucleotide sequenc
A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the duplex region of the RNA and of a portion of the target gene are identical. The present invention is distinguished from prior art interference in gene expression by antisense or triple-strand methods.
Owner:CARNEGIE INSTITUTION OF WASHINGTON +1

Hormone normalization therapy and uses therefor

The present invention discloses a novel method of prevention of birth defects, miscarriages and infertility in women. The two therapies, disclosed herein, the hormone normalization therapy and the aromatase inhibitor-hormone normalization therapy, focus on restoring young hormonal levels in women in order to prevent female infertility and miscarriages, guide follicular and oocyte maturation, and promote correct chromosomal segregation in oocytes and early embryos.
Owner:BERNSTEIN LORI R

Humidifier with ultraviolet disinfection

A humidifier for treating humidified air with germicidal light is provided. The humidifier includes a water reservoir, an atomizer to atomize a supply of water, and an ultraviolet light source to expose the atomized water to germicidal light. The ultraviolet light source extends vertically within a cylindrical channel to irradiate the atomized water dissipating upwardly from the atomizer. The water reservoir can include a carbon filter and a hardness-removing module for removing containments and metal oxides from the water supply. A control panel indicates the remaining useful life of the ultraviolet light source, the carbon filter and the hardness-removing module based on historical humidifier usage and water quality levels.
Owner:ACCESS BUSINESS GRP INT LLC

Genetic inhibition by double-stranded RNA

A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the duplex region of the RNA and of a portion of the target gene are identical. The present invention is distinguished from prior art interference in gene expression by antisense or triple-strand methods.
Owner:UNIV OF MASSACHUSETTS +1

AGV optimization scheduling method based on mixed particle swarm optimization

The invention relates to an AGV optimization scheduling method based on mixed particle swarm optimization. First of all, a mathematics model is abstracted from the work process of an AGV, and an object function of a scheduling scheme is determined, and secondly, the model is solved by use of the mixed particle swarm optimization based on a genetic algorithm, a stimulated annealing algorithm and ant colony optimization, and an optimization scheduling scheme is generated. According to the invention, a contrast analysis is made between the mixed particle swarm optimization and standard particle swarm optimization through examples, and the variation operation of the mixed optimization employs an ant colony optimization thinking mode, ensures intersection of individual best and group best in an intersection operation process, ensures the feasibility of the mixed particle swarm optimization and has the validity for solving large-scale scheduling tasks.
Owner:SHANGHAI JINGXING LOGISTICS EQUIP ENGCO

Selective inhibitors for protein kinases and pharmaceutical composition and use thereof

The present invention provides a compound of formula (I) or the salt thereof:wherein R is at least one selected from the group consisting of unsubstituted C1-4 alkyl, C1-4 alkyl substituted by C6-18 aryl or —OR1, and —C(═O)Z. The compound is a type-S protein kinase inhibitor, which binds to an ATP-binding site and a substrate-recognition site of a protein kinase simultaneously. The present invention further provides a pharmaceutical composition, which includes a compound of formula (I) or a salt and a pharmaceutically acceptable carrier thereof. The present invention further provides a use of a compound of formula (I) or a salt thereof, which is for the manufacture of a protein kinase inhibitor as a drug.
Owner:NAT CHIAO TUNG UNIV

Process For Purification Of Aromatic Carboxylic Acids

InactiveUS20080103333A1Reduced level of impurityEfficient use and handlingOrganic compound preparationMetal/metal-oxides/metal-hydroxide catalystsSolventCarbonyl group
Impure aromatic carboxylic acids such as are obtained by liquid phase oxidation of feed materials comprising aromatic compounds with substituent groups oxidizable to carboxylic acid groups, or comprising aromatic carboxylic acid and one or more aromatic carbonyl impurities that form hydrogenated species more soluble in aqueous solvents or with less color or color-forming tendencies than the aromatic carbonyl impurity, are purified to an aromatic carboxylic acid product with lower levels of impurities by a process comprising contacting an aqueous solution comprising the impure aromatic carboxylic acid with hydrogen at elevated temperature and pressure with an attrition-resistance, acid stable catalyst composition comprising at least one hydrogenation catalyst metal and a support comprising relatively high surface area silicon carbide.
Owner:BP CORP NORTH AMERICA INC

Master node, slave node, system and method for mirror image management of distributed container cluster

The invention discloses a distributed container cluster mirror image management master node, slave nodes, a system and a method, wherein the main node comprises a mirror image database which is a distributed database and is used for storing node information of all nodes in the system; the request input module is used for receiving request content including a request target and command execution content; mirror image management module, the verification module is used for communicating the password and verifying whether the request content acquired by the request record input module is legal; ifit is judged that a request target in the request content is a specified single slave node or grouped slave nodes, sending a communication password and command execution content including a pulling operation, an updating operation, a deleting operation and a cleaning operation to IP addresses corresponding to the slave nodes; and receiving the state feedback content sent by the slave node. According to the invention, the flattening management of the container cluster mirror image is realized, the management efficiency of the cluster container mirror image in a distributed system is improved,and the high reliability and safety of the whole cluster are improved.
Owner:NANJING UNIV OF POSTS & TELECOMM

Message pushing method and device, computer equipment and storage medium

ActiveCN108460115AAvoid pushing duplicate or invalid messagesAvoid duplicationWeb data indexingError avoidanceUser identifierComputer equipment
The invention discloses a message pushing method and device, computer equipment and a storage medium. The method comprises the following steps of: obtaining a message pushing task, wherein the messagepushing task comprises a message pushing task ID and at least one user ID; querying a database on the basis of the message pushing task ID, so as to obtain target message task data, a task state of which is a to-be-pushed state; verifying the target message task data by adoption of at least one verification rule so as to obtain a verification result; and if the verification result is passing theverification, pushing the target message task data to a client corresponding to the at least one user ID, and updating the task state of the target message task data to a pushing success state. According to the message pushing method, target message task data in a to-be-pushed state can be sent to clients of corresponding user IDs, so that the condition of pushing repeated messages or ineffectivemessages is avoided.
Owner:ONE CONNECT SMART TECH CO LTD SHENZHEN

Enhanced electrochemical deposition (ECD) filling of high aspect ratio openings

InactiveUS6869515B2Increase inhibition (or suppression) differentiationEnhancing void-free superfilling mechanismCellsSemiconductor/solid-state device detailsJet flowHigh pressure
Owner:COHEN URI

Chip scale LED (light emitting diode) package structure

The invention discloses a chip scale LED package structure. The chip scale LED package structure comprises an LED chip with electrodes on the bottom surface, and a package adhesive body which packs the top surface and the side surfaces of the LED chip. At least one of the bottom and the side surface of the package adhesive body is provided with a reflect surface which is a reflective curved surface or a reflective flat surface extending from the bottom of the package adhesive body to the side surface of the package adhesive body. By arranging the reflective surfaces with high reflectivity on the bottom surface and / or the side surface of the package adhesive body, the chip scale LED package structure can effectively the deficiency that light is emitted out from the bottom or the side surface of the package adhesive body to result in ineffective light extraction, thereby improving the light extraction efficiency of products and reducing light losses; besides, by means of the reflective surfaces on the side surface and the bottom surface of the package adhesive body, the chip scale LED package structure can well control the light emitting angles of the products, facilitating formation of a single light exiting surface and further facilitating using compatibility of the products on different occasions. The chip scale LED package structure can be widely applied to manufacturing chip scale package LED products in the fields such as backlight and lighting.
Owner:SHENZHEN REFOND OPTOELECTRONICS

Vehicle collision early warning control method and system based on millimeter wave radar and vehicle

The invention provides a vehicle collision early warning control method and system based on a millimeter wave radar and a vehicle. The control method comprises the following steps that the obstacle information identified by the millimeter wave radar is obtained; the obstacle information is processed to obtain a transverse relative distance optimal estimation value, a longitudinal relative distanceoptimal estimation value, a transverse relative speed optimal estimation value and a longitudinal relative speed optimal estimation value; a movement track of an obstacle is established; the longitudinal encounter time and a corresponding transverse relative distance between the vehicle and the obstacle are predicted; and whether a collision risk exists between the vehicle and the obstacle or notis judged; and if yes, a LED light source, corresponding to the current position of the obstacle, in a vehicle long-range lamp is controlled to flash for collision early warning. The millimeter waveradar is adopted as a sensing sensor, the positioning precision of the obstacle is effectively improved, the track tracking and prediction precision of the obstacle are greatly improved, the collisionprediction precision is greatly improved, the reliability of vehicle collision early warning is improved, and the driving safety is improved.
Owner:BEIJING HAINACHUAN AUTOMOTIVE PARTS

Agricultural product production and marketing integration service platform based on Internet and large data

The invention discloses an agricultural product production and marketing integration service platform based on Internet and large data. The platform comprises a data excavation subsystem used by a user and an agricultural data analysis subsystem, wherein the data excavation subsystem is used for effective collection needed by the user and excavating data; and the agricultural data analysis subsystem is used for carrying out refinement management on agricultural production In the invention, production and market demands are tightly cooperated, an effective service is realized and an original profit mode is changed; the service is integrated with a production and marketing service of agricultural products, services are provided for a consumer, an agricultural producer or a cooperative, and a final purpose is to realize a customized and multi-type C2B order type agricultural production and marketing service mode; and the agricultural product production and marketing integration service platform is constructed and an agricultural product production and marketing integration service is realized so that an agricultural production level can be effectively increased and the agriculture performs a great effect in GDP growth, and simultaneously an income level of agricultural population is improved, acceptance of labor forces is increased and new rural construction is promoted.
Owner:四川省巴食巴适电子商务有限公司

Method for coating a suture

The method of the present invention is for coating a suture thread. The suture thread is coated with a protein film, such as fibrinogen. An active enzyme inhibitor, such as a matrix metallo proteinase inhibitor, is immobilized to or associated with the film.
Owner:ASPENBERG PER VILHELM +2

Rainfall amount-based geological disaster monitoring method and system

The embodiment of the invention provides a rainfall amount-based geological disaster monitoring method and system. The method comprises the following steps: a base station monitors rainfall amount data of a region to be monitored to obtain the rainfall amount data of the region to be monitored; a corresponding control strategy is obtained according to the rainfall amount data, and is sent to an on-site acquisition terminal; the on-site acquisition terminal acquires disaster data of the region to be monitored according to the control strategy, and sends the acquired disaster data to a server through the base station, wherein the disaster data comprise at least one of inclination angle data, displacement data, settling data, prestress and seepage pressure data; the server analyzes the disaster data, thus obtaining an analysis result corresponding to a current geological disaster monitoring situation. According to the rainfall amount-based geological disaster monitoring method provided by the invention, the problem that in case of a geological disaster, key monitoring indexes cannot be measured and recorded in time and effectively due to the suddenness and the contingency of the geological disaster is avoided, and prewarning of the geological disaster is realized.
Owner:CHENGDU UNIVERSITY OF TECHNOLOGY

Production method of oversized-diameter anode phosphorus copper ball

The invention belongs to the technical field of phosphorus copper balls for electroplating and particularly relates to a production method of an oversized-diameter anode phosphorus copper ball. The method comprises the following steps of: firstly melting pure copper and phosphorus copper intermediate alloy to obtain a phosphorus copper alloy solution and producing a phosphorus copper alloy rod by utilizing the uniformly mixed phosphorus copper alloy solution through an upward casting method; feeding the obtained phosphorus copper alloy rod into a continuous extruding machine for extrusion, wherein the phosphorus copper alloy rod is driven by an extrusion wheel to be forcedly pressed into an extrusion cavity and is extruded according to the designed size so as to obtain an ultra-fine grain phosphorus copper rod blank; and finally performing cold heading and molding on the obtained ultra-fine grain phosphorus copper rod blank by utilizing a cold header, so as to form phosphorus copper ball of design specification. The phosphorus copper ball obtained by utilizing the production method has a smooth, round and complete surface and a compact internal crystal structure, and has the advantage of obviously improved appearance and internal quality compared with the phosphorus copper ball obtained by utilizing an existing technology.
Owner:铜陵有色股份铜冠电工有限公司

Methods for diet and weight control by altering the senses of smell and taste

This invention comprises a method for diet and weight control by altering the senses of smell and taste. The topically applied composition hinders the use of the olfactory nerves by either chemical or mechanical means. A further embodiment comprises a scent diffuser that blocks a food's smell. The loss of smell and taste caused by the composition and devices effectively decreases the appetite of an individual, enabling the individual to eat less and lose weight.
Owner:JACKSON MILTON S

Baseband precoding MSK signal demodulation method based on deep learning under pulse noise

The invention belongs to the technical field of communication, and relates to a baseband precoding MSK signal demodulation method based on deep learning under pulse noise. The demodulation method based on deep learning is designed to solve the problem that pulse noise model parameter estimation is complex when a traditional baseband precoding MSK signal is demodulated. According to the method, under the condition that a channel model is not known, a channel feature training demodulation network can be learned from transmitting and receiving data, a transmitting sequence is recovered or codingbit soft information is output at a receiving end in real time, reliable receiving is guaranteed, and meanwhile operation complexity is reduced.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Therapeutic contact lenses with anti-fungal delivery

A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed preferably mimic receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. A system in accordance with an embodiment of the invention is a contact lens for delivering a drug through contact with an eye. In a particular embodiment of the invention, the drug is an anti-microbial, such as an anti-fungal agent for treatment of large animals, such as horses.
Owner:AUBURN UNIV

Antimicrobial multilayer wound dressing

A wound dressing includes one or more layers containing an antimicrobial agent and optionally at least one of: a chelating agent, a second antimicrobial agent, a zinc-containing agent, a cell-signaling agent, and an additional active ingredient or agent.
Owner:TYCO HEALTHCARE GRP LP

Recommendation method and device for Web service combination

The invention provides a recommendation method and a device for Web service combinations. The method includes obtaining a Web service combination requirement of a user, wherein the Web service combination requirement comprises at least two Web service function requirements; determining candidate service combinations corresponding to each Web service function; performing association rules analysis on historically called service combinations, determining candidate Web service with a frequency index larger than that of a preset standard in the candidate service combinations, and generating a frequency service combination including the candidate Web service with the frequency index larger than that of the preset standard; performing service combination relation analysis on the Web service combinations to obtain at least two combination relations between the Web service combination requirements; and determining recommendation Web service corresponding to each Web service function requirement to form recommendation Web service combinations according to the frequency indexes of each candidate Web service in the frequency service combination and global quality of service (QoS) attribute which uses the candidate Web service on the basis of the combination relations.
Owner:BEIHANG UNIV

Method and system for sending messages

The invention provides a method and a system for sending messages. The method comprises the following steps of judging whether the state of each message sending progress in the N message sending progresses is a valid state or not; determining the states of K message sending progresses to be valid states from the N message sending progresses on the basis of judgment, wherein K is integer which is greater than 1 but less than or equal to N; determining one message sending progress from the K message sending progresses to be a main message sending progress; starting a message scheduler in a message task server where the main message sending progress is positioned by the main message sending progress; acquiring at least one message to be sent without progress attribution from a message queue of a database by the message scheduler; allocating one message sending progress for each message to be sent in at least one message to be sent without progress attribution; and sending at least one message to be sent without progress attribution by K message sending progresses.
Owner:ALIBABA GRP HLDG LTD

Treatment of organic materials

Processes for the treatment of solutions used for the decontamination of radioactively contaminated surfaces wherein the solution contains radioactive metal ions and organic complexing agents are described herein. The processes include treating the solutions with a reagent suitable for the destruction of the complexing agent and contains a metal capable of existing in more than one oxidation state, and raising the pH of the resultant solution to a level at which the metal of the reagent precipitates or flocs out of the solution. Processes in which the contaminated solutions are treated with electromagnetic radiation, treated with UV or visible radiation, and treated at an ambient temperature are also described herein.
Owner:NUCLEAR DECOMMISSIONING AUTHORITY

Abnormity identification method and monitoring platform for domestic sewage treatment facility

The invention discloses an abnormity identification method and a monitoring platform for domestic sewage treatment facility. The method comprises the following steps: S1, acquiring current and outletflow data of a sewage lift pump in a normal working state within a specific time, and current and outlet flow data of the sewage lift pump before a fault occurs and within a specific time, so as to construct an abnormity analysis data set, S2, performing clustering analysis on the abnormity analysis data set through a clustering algorithm to obtain an abnormity data cluster; S3, obtaining a numerical boundary according to the exception type data cluster, and constructing an abnormity identification model; S4, collecting current and outlet flow data of the sewage lift pump, and inputting the current and outlet flow data into the abnormality identification model to perform abnormality judgment, and further performing sequential analysis on the abnormal data cluster to obtain a time boundary,and adding the time boundary into the abnormal recognition model. According to the abnormity identification method, comprehensive judgment is carried out on the data in the time boundary, and early warning can be carried out on initial abnormal operation of the sewage treatment facility.
Owner:NAT ENG RES CENT OF DREDGING TECH & EQUIP

Rotor nonlinear kinetic characteristic simulation experiment device under multi-field coupling action

The invention provides a rotor nonlinear kinetic characteristic simulation experiment device under a multi-field coupling action. A gas radial bearing, a gas thrust bearing and a gas radial-thrust joint bearing are utilized for simulating a function of a gas flow field; a permanent magnetic rotor and a stator coil are utilized for simulating a function of a magnetic field force; a flexible design of the permanent magnetic rotor is utilized for simulating a rotor elastic deformation function; an exciter is utilized for simulating exciting loads in different forms; an active control rubber vibration isolator is utilized for simulating varied and flexible conditions of an experiment table. The device provided by the invention can be used for simulating a rotor nonlinear kinetic characteristic of a micro gas turbine and high speed permanent magnet motor rotor system under a gas bearing supporting action, a gas-elasticity coupling action, a gas-elasticity-magnetism multi-field coupling action, a multi-exciting force action, and varied and flexible conditions, so that the accuracy of the micro gas turbine and high speed permanent magnet motor rotor system kinetic analysis is improved, and an experiment reference base is provided for simulating calculation.
Owner:INST OF ENGINEERING THERMOPHYSICS - CHINESE ACAD OF SCI

Cartridge-type bearing seal for machine tool spindle

A cartridge type bearing seal facilitates the prevention of contaminant ingress between a spindle rotor and a spindle housing, particularly in situations where a circumferentially uniform fluid pressure is generated within the annular volume of the spindle housing. The cartridge includes ringlike rotor and stator sections which can be compressed axially to snap fit together, in a manner which enables relative rotation about a common axis. When interconnected, the sections define an inside surface and an outside surface, and a fluid flow path which extends radially outwardly therebetween, and which traverses a collar and tangs construction which enables the snap fit connection. The tangs are arcuate in shape and spaced equidistantly around the axis. The total arcuate space occupied by the tangs is relatively small, compared to the total arcuate space residing between the tangs, and bounded by the two sections adjacent the collar. This structure allows the pressurized purge fluid to flow outwardly from the cartridge during use, to prevent contaminant ingress during operation of the spindle. This construction may be readily adapted to accommodate a spindle of virtually any size or shape, at relatively low cost, and is particularly suitable for retrofitting an existing spindle which has experienced a failed seal.
Owner:SETCO SALES
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