The invention discloses
carnitine grafted
polyvinyl alcohol cross-linked hydrogel and a preparation method and application thereof, and belongs to the technical field of food, health care products or
medical instruments.The
carnitine grafted
polyvinyl alcohol cross-linked hydrogel is obtained by
grafting L-
carnitine with
polyvinyl alcohol in an acid environment and then conducting cross-linking through polycarboxylic acid. The preparation process does not use organic solvents, and is simple, economical and convenient. The
grafting rate of the L-carnitine grafted polyvinyl
alcohol is 1%-30%, and the swelling multiple of the carnitine grafted polyvinyl
alcohol cross-linked hydrogel is 50-150 times when the carnitine grafted polyvinyl
alcohol cross-linked hydrogel reaches swelling equilibrium in an acidic
aqueous solution with the pH value of 2. The carnitine grafted polyvinyl alcohol cross-linked hydrogel disclosed by the invention is large in water absorption expansion times under an acidic condition, increases the volume occupying the
stomach to provide satiety and reduces
food intake, is limited in water absorption times or degraded and collapsed under a neutral / alkaline condition, is beneficial to being discharged out of a body, can be used for preparing weight-losing products, assists in controlling diet, and has a good market prospect. The effects of preventing or assisting in treating
obesity and diseases caused by
obesity and the like are achieved.