The invention relates to an artificial propagating method of semilabeo obscurus and belongs to the technical field of fish product culture. According to the method, domperidone and lutein releasing hormone A2 are injected in gonadosomatic semilabeo obscurus according to a dosage that 1mg of domperidone and 1mug of lutein releasing hormone A2 are injected for each kilogram of body weight, the injection dosage is reduced to a half for milters, and the artificial wet process fertilization is carried out at the effect time of 22 hours and at the water temperature being 21 DEG C; ova and sperms of the gonadosomatic semilabeo obscurus are extruded into a container, 21-DEG C clean water is immediately poured into the container, and the water quantity is proper when the ova and sperms are immersed; then, the ova and sperms are slightly stirred for 30 seconds by chicken feather, and next, the incubation is prepared after the washing by clean water for three times; firstly, the fertilized ova are placed into 0.15ppm Tuzet water solution to be soaked for 15 minutes for sterilization and are then placed into large basins containing 60kg water, 3000 ova with the ovum diameter being 2.2 to 2.5 mm are placed into each basin, oxygenation is carried out through an oxygenation pump, the water temperature is 21 to 22 DEG C, the pH is 7.8 to 8.5, the incubation lasts 36 hours, the complicated reticular yolk system and the well developed somite and blood vessels can be clearly seen, and the semilabeo obscurus fry is obtained after 72-hour hatching. The artificial propagating method has the advantages that the cost is low, the operation is simple and convenient, the hatching rate is high, and the artificial propagating method can be put into production and practical use.