Hydrogel for assisting in controlling diet and preparation method and application thereof

An auxiliary control and hydrogel technology, which is applied in the field of medical assistance, can solve the problems of gel group volume affecting gastrointestinal digestion and small expansion rate, and achieve the effect of good satiety and good collapse solubility

Active Publication Date: 2021-01-26
吴良平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, methyl cellulose cannot evenly contact with water in the body. The outer layer absorbs water and swells into micelles, which will prevent water from entering the inner layer, resulting in a small expansion rate. It needs to be taken in large quantities to meet the functional requirements, and the formed gel group may have a large volume. affect gastrointestinal digestion

Method used

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  • Hydrogel for assisting in controlling diet and preparation method and application thereof
  • Hydrogel for assisting in controlling diet and preparation method and application thereof
  • Hydrogel for assisting in controlling diet and preparation method and application thereof

Examples

Experimental program
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Embodiment 1

[0041] This example is an embodiment of the hydrogel for assisting diet control of the present invention. The types of raw materials used in the hydrogel for assisting diet control in this embodiment and the amount of each raw material are shown in Table 1, which mainly consists of the following raw materials in parts by weight Cross-linked: 80.0 parts by weight of sodium carboxymethyl cellulose, 20.0 parts by weight of hydroxyethyl cellulose, and 1.0 parts by weight of citric acid; wherein the manufacturers and models of sodium carboxymethyl cellulose are shown in Table 2, and its DS ( The degree of substitution) is 0.7-1.2, and the viscosity of an aqueous solution with a mass concentration of 1% prepared by the sodium carboxymethylcellulose at 25°C is 5000-15000mPa·s; the manufacturer and model of hydroxyethylcellulose As shown in Table 2, the viscosity of the aqueous solution with a mass concentration of 2% prepared from the hydroxyethyl cellulose at 25° C. is 300-400 mPa·s....

Embodiment 2-7

[0054] Examples 2-7 are all one embodiment of the hydrogel for assisting diet control of the present invention. The types of raw materials used in these hydrogels for assisting diet control and the amount of each raw material are shown in Table 1. The preparation method is the same as in Example 1. Wherein used sodium carboxymethyl cellulose and water-soluble polysaccharide macromolecule producer and model are respectively as described in Table 2.

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Abstract

The invention discloses hydrogel for assisting in controlling diet and a preparation method and application thereof, and belongs to the technical field of medical assistance. The hydrogel with pH sensitivity is prepared by taking sodium carboxymethylcellulose, water-soluble polysaccharide macromolecules and polybasic carboxylic acid as raw materials and performing cross-linking reaction; the obtained hydrogel can swell in acidic gastric juice and neutral small intestine juice and can scatter and dissolve in alkaline colon juice; and by controlling the using amount of the polybasic carboxylic acid and adopting the non-ionic water-soluble polysaccharide macromolecules, the obtained hydrogel has a higher swelling ratio in a stomach acidic environment. The hydrogel disclosed by the invention can be used for preparing hydrogel capsules for assisting in controlling the diet, is safe and harmless to a human body, has very good satiety and does not influence the absorption of the human body tonutrients.

Description

technical field [0001] The invention belongs to the technical field of medical assistance, and in particular relates to a hydrogel for assisting diet control, a preparation method and application thereof. Background technique [0002] In 2016, the famous British medical journal "The Lancet" published a survey report on the weight of adults worldwide. The survey found that my country's obese population exceeded 90 million, surpassing the United States to become the country with the largest obese population in the world, including 43.2 million men and 46.4 million women, respectively. Accounting for 16.3% and 12.4% of the world. In the past few decades, obesity has become a global epidemic disease. Obesity will also be accompanied by complications, including diabetes, fatty liver, hypertension, coronary heart disease, sleep apnea syndrome, etc. Severe obesity may also induce myocardial Infarction and stroke seriously threaten people's health. At present, the main methods for ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00A23L29/20
CPCA23L33/00A23L29/20A23V2002/00A23V2200/228A23V2200/332A23V2250/51088A23V2250/51086A23V2250/032A23V2250/5108A23V2250/044A23V2250/02A23V2250/5024A23V2250/036A23V2250/056
Inventor 吴良平戴晓江黄红艳
Owner 吴良平
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