The invention discloses a method for improving lignocellulose enzymolysis and saccharification efficiency, which comprises the following steps: mixing sheared lignocellulose material, ethanol, sulfuric acid and water, and heating in a high-temperature and high-pressure resisting sealed reactor to carry out pretreatment reaction to obtain a mixture; neutralizing the obtained mixture by using an alkali, separating solid from liquid, and distilling the liquid, wherein the component distilled out is ethanol, and the liquid left in a distiller is a solution rich in pentose; drying the solid, adding cellulase and water, and adjusting the pH value, and performing enzymolysis, wherein the liquid re-separated from the solid is the solution rich in the glucose. The method has the advantages that the pretreatment temperature is lower than the pretreatment temperature of the common diluted acid, the content of hemicellulose and lignin in the solid obtained through pretreatment is low, the conversion rate of glucose is high due to enzymolysis, the used ethanol can be recycled, and the fermentation inhibitor in sugar liquid is less pretreated than the common diluted acid.